Stacey Zhou - Academia.edu (original) (raw)

Papers by Stacey Zhou

Chinese Optics Letters, 2011

Nonlinear Analysis: Real World Applications, 2009

财经与管理, 2020

金融科技最基本的思路就是通过运用科学技术来促进金融行业有更大的创新突破，以此来提高金融机构自身的竞争实力。根据研究可知，大数据平台以及智慧城市是可以最大限度推动金融改革与发展的有力保障。论文针对... more 金融科技最基本的思路就是通过运用科学技术来促进金融行业有更大的创新突破，以此来提高金融机构自身的竞争实力。根据研究可知，大数据平台以及智慧城市是可以最大限度推动金融改革与发展的有力保障。论文针对城市大数据平台和金融科技在金融改革和发展中的问题、应用方向进行详细分析地。论文以中国某市为例，介绍了其应用大数据设计信息平台为人们提供更加科学、准确、便捷的服务。

Journal of Physics: Conference Series, 2021

The TiCN coatings were successfully prepared by means of reactive plasma with spraying self-made ... more The TiCN coatings were successfully prepared by means of reactive plasma with spraying self-made composite powder prepared from 150°C to 350°C in the paper. Sucrose was used as a carbon source, using the means of Precursor body carbon, sucrose and titanium powder mixing at high temperature after the heat treatment furnace for carbonization. Finally, the titanium powder was wrapped by the carbon, so the composite powder was mixed more uniform and could react more fully. TiCN coatings could not be synthesized with the composite powder prepared the temperatures of 150°C and 250°C, because the sucrose was not carbonized totally and could not carbonize to synthesize TiCN with Ti and N2 in the process of spraying. TiCN coatings were prepared by spraying the composite powder under heat treatment at 350°C and which composed of Ti and C at a ratio of 1:3. The phase compositions, the morphologies, the hardness and the microstructures were analyzed. The results showed that TiCN coating was con...

Archives of Biochemistry and Biophysics, 1998

completely prevented by coincubation of cells with ferricyanide or Tempol. The data in this study... more completely prevented by coincubation of cells with ferricyanide or Tempol. The data in this study suggest In addition to the broad repertoire of regulatory that nitroxyl may contribute to the cytotoxicity associfunctions nitric oxide (NO) serves in mammalian physated with an enhanced expression of the L-arginine:NO iology, the L-arginine:NO pathway is also involved in pathway under different biological conditions. ᭧ 1998 numerous pathophysiological mechanisms. While NO Academic Press itself may actually protect cells from the toxicity of reactive oxygen radicals in some cases, it has been suggested that reactive nitrogen oxide species formed from nitric oxide synthase (NOS) can be cytotoxic. In Nitric oxide (NO) has been postulated as a causative addition to NO, the one electron reduction product agent in a variety of pathophysiological states. How-NO 0 has been proposed to be formed from NOS. We ever, effects ascribed to NO are often mutually contrainvestigated the potential cytotoxic role of nitroxyl dictory and have therefore been a source of some confu-(NO 0), using the nitroxyl donor Angelis's salt, (AS; sosion (1). For instance, NO, in the presence of oxygen dium trioxodinitrate, Na 2 N 2 O 3) as the source of NO 0. or superoxide, can generate reactive nitrogen oxide spe-AS was found to be cytotoxic to Chinese hamster V79 cies (RNOS) 2 , which can oxidize nitrate, or nitrosate, lung fibroblast cells over a concentration range of 2-4 mM. The presence of equimolar ferricyanide (Fe(III)-other biomolecules (2, 3). RNOS are proposed to medi-(CN 6) 30), which converts NO 0 to NO, afforded dramatic ate various toxic and cytotoxic mechanisms. In conprotection against AS-mediated cytotoxicity. Treattrast, NO can protect cells from damage caused by reacment of V79 cells with L-buthionine sulfoximine to retive oxygen species (ROS) (4-6), as a result of different duce intracellular glutathione markedly enhanced AS chemical reactions than those involving RNOS (7-10). cytotoxicity, which suggests that GSH is critical for NO participates in chemical reactions associated cellular protection against the toxicity of NO 0. Furwith both oxidative and nitrosative stress which can ther experiments showed that low molecular weight have deleterious consequences in vivo. Studies suggest transition metal complexes associated with the formathat there exists a balance between NO and two of tion of reactive oxygen species are not involved in ASthe major reactive nitrogen oxide species, dinitrogen mediated cytotoxicity since metal chelators had no eftrioxide (N 2 O 3) and peroxynitrite (ONOO 0) (11-13) fect. However, under aerobic conditions, AS was more that can determine the toxicological outcome under toxic than under hypoxic conditions, suggesting that oxygen dramatically enhanced AS-mediated cytotoxicity. At a molecular level, AS exposure resulted in DNA

Journal of Physics: Conference Series, 2020

Combination of the load-bearing conditions, the tower shape and service time, and the geological ... more Combination of the load-bearing conditions, the tower shape and service time, and the geological and basic conditions of the service environment of the tower, various factors that influence the stability of the towering tower near goaf were classified by using fuzzy comprehensive evaluation method and AHP, and the influence factor model was established. The impact factors were evaluated from low to high, the influence of the geological and basic conditions of the service environment is maximal, and determined the approximate rock roadway is stable and no measures need to take to improve the stability of the tower.

Journal of Biological Chemistry, 1997

The Journal of organic chemistry, Jan 7, 2014

This paper describes the synthesis and systematic study of substituted acenes that have differenc... more This paper describes the synthesis and systematic study of substituted acenes that have differences in conjugation both along their long axes (by the number of fused benzene or thiophene rings) and along their short axes (by the number of arylethynyl substituents). These acenes include what we believe to be the first reported examples of five new subclasses of substituted acenes. Systematic analyses of data obtained using absorbance and fluorescence spectroscopies, cyclic voltammetry, and DFT calculations reveal clear correlations between these common structural perturbations to acene structure and the key parameters, such as HOMO-LUMO gap, frontier molecular orbital energies, and reactivity with singlet oxygen.

Journal of Film and Video, 2005

A JAZZ MUSICIAN, FRED MADISON (BILL PULL MAN), catches on to the fact that his wife, Renee (Patri... more A JAZZ MUSICIAN, FRED MADISON (BILL PULL MAN), catches on to the fact that his wife, Renee (Patricia Arquette), is having an affair. Fred is anxiety-ridden and cannot sleep; he's heading for a psychotic breakdown, which fi nally happens at a party when the Mystery Man ...

High penetration of renewable energy source makes microgrid (MGs) be environment friendly. Howeve... more High penetration of renewable energy source makes microgrid (MGs) be environment friendly. However, the stochastic input from renewable energy resource brings difficulty in balancing the energy supply and demand. Purchasing extra energy from macrogrid to deal with energy shortage will increase MG energy cost. To mitigate intermittent nature of renewable energy, energy trading and energy storage which can exploit diversity of renewable energy generation across space and time are efficient and cost-effective methods. But a storage with large capacity will incur additional cost. In addition, due to MG participating energy trading as prosumer, it calls for an efficient trading mechanism. Therefore, this paper focuses on the problem of MG energy management and trading. Energy trading problem is formulated as a stochastic optimization one with both individual profit and social welfare maximization. Firstly a Lyapunov optimization based algorithm is developed to solve the stochastic problem. Secondly the double-auction based mechanism is provided to attract MGs' truthful bidding for buying and selling energy. Through theoretical analysis, we demonstrate that individual MG can achieve a time average energy cost close to offline optimum with tradeoff between storage capacity and energy trading cost. Meanwhile the social welfare is also asymptotically maximized under double auction. Simulation results based on real world data show the effectiveness of our algorithm.

2018 International Conference on Power System Technology (POWERCON), 2018

Along with the development of UHV technology, an extra-large-scaled AC / DC hybrid power grid has... more Along with the development of UHV technology, an extra-large-scaled AC / DC hybrid power grid has been accomplished in China, the characteristics of the power system is facing profound changes, the techs of simulations are needed to be improved as well to meet the new requirements. The electromagnetic transient simulation is often used to model DC system to obtain more accurate dynamic characteristics. However, the operation status adjustment and initialization process of the EMT model of DC systems seriously affect the efficiency in simulation of AC/DC power grids. In this paper, a method of auto-initializing the electromagnetic model of DC transmission is proposed. Using the AC/DC large-scale network power flow as the boundary condition, the internal power flow solution of the DC electromagnetic model is quickly calculated, and the initial on-valves, the position of converter transformer’s tap, the AC filters’ switching scheme, and the control instructions are accurately determined. This solution enables the automatic initialization of the UHVDC electromagnetic model so that it can reach a predetermined steady state during the 0.5 s simulation. The method proposed in this paper realizes the fast and smooth start-up of the electromechanical-electromagnetic transient hybrid simulation with a large number of electromagnetic UHVDC models, and solves the application problems of the electromechanical-electromagnetic transient hybrid simulation in operation mode calculation and online simulation of power grid.

JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, a... more JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact

arXiv (Cornell University), Feb 9, 2017

High penetration of renewable energy source makes microgrid (MGs) be environment friendly. Howeve... more High penetration of renewable energy source makes microgrid (MGs) be environment friendly. However, the stochastic input from renewable energy resource brings difficulty in balancing the energy supply and demand. Purchasing extra energy from macrogrid to deal with energy shortage will increase MG energy cost. To mitigate intermittent nature of renewable energy, energy trading and energy storage which can exploit diversity of renewable energy generation across space and time are efficient and cost-effective methods. But current energy storage control action will impact the future control action which brings challenge to energy management. In addition, due to MG participating energy trading as prosumer, it calls for an efficient trading mechanism. Therefore, this paper focuses on the problem of MG energy management and trading. Energy trading problem is formulated as a stochastic optimization one with both individual profit and social welfare maximization. Firstly a Lyapunov optimization based algorithm is developed to solve the stochastic problem. Secondly the double-auction based mechanism is provided to attract MGs' truthful bidding for buying and selling energy. Through theoretical analysis, we demonstrate that individual MG can achieve a time average energy cost close to offline optimum with tradeoff between storage capacity and energy trading cost. Meanwhile the social welfare is also asymptotically maximized under double auction. Simulation results based on real world data show the effectiveness of our algorithm.

Bacteria come in a variety of shapes. While the peptidoglycan (PG) cell wall serves as an exoskel... more Bacteria come in a variety of shapes. While the peptidoglycan (PG) cell wall serves as an exoskeleton that defines the static cell shape, the internal bacterial cytoskeleton mediates cell shape by recruiting PG synthesis machinery and thus defining the pattern of cell-wall synthesis. While much is known about the chemistry and biology of the cytoskeleton and cell wall, much of their biophysics, including essential aspects of the functionality, dynamics, and organization, remain unknown. This dissertation aims to elucidate the detailed biophysical mechanisms of cytoskeleton guided wall synthesis. First, I find that the bacterial cytoskeleton MreB contributes nearly as much to the rigidity of an Escherichia coli cell as the cell wall. This conclusion implies that the cytoskeletal polymer MreB applies meaningful force to the cell wall, an idea favored by theoretical modeling of wall growth, and suggests an evolutionary origin of cytoskeleton-governed cell rigidity. Second, I observe that MreB rotates around the long axis of E. coli, and the motion depends on wall synthesis. This is the first discovery of a cell-wall assembly driven molecular motor in bacteria. Third, I prove that both cell-wall synthesis and the PG network have chiral ordering, which is established by the spatial pattern of MreB. This work links the molecular structure of the cytoskeleton and of the cell wall with organismal-scale behavior. Finally, I develop a mathematical model of cytoskeleton-cell membrane interactions, which explains the preferential orientation of different cytoskeleton components in bacteria.

Cell Motility and the Cytoskeleton, 1998

Pg is a homologue of beta-catenin and Armadillo, the product of the Drosophila segment polarity g... more Pg is a homologue of beta-catenin and Armadillo, the product of the Drosophila segment polarity gene and has been shown to have both adhesive and signaling functions. It interacts with both classic and desmosomal cadherins. Pg interaction with the desmosomal cadherins is essential for desmosome assembly. Its precise role in the classic cadherin complexes is unclear, although Pg-E-cadherin interaction appears to be necessary for the formation of desmosomes. In addition to cadherins in adhesion complexes, Pg interacts with a number of proteins involved in regulation of cell differentiation and proliferation such as Lef-1/Tcf-1 transcription factors and the tumor suppressor protein APC. In this study, we have introduced Pg cDNA into SCC9 cells, a Pg- and E-cadherin-deficient squamous cell carcinoma line, which also lacks desmosomes. These cells have both alpha-catenin and beta-catenin, display unusual expression of N-cadherin, and have the typical fibroblastic phenotype of transformed cells. Pg-expressing SCC9 cells (SCC9P) formed desmosomes. Desmosome formation coincided with the appearance of an epidermoid phenotype, with increased adhesiveness and a contact-dependent decrease in growth. Biochemical characterization of SCC9P cells showed an increase in the expression and stability of N-cadherin and a decrease in level and stability of beta-catenin, without any apparent effects on alpha-catenin. These results show that, in the absence of E-cadherin, Pg can efficiently use N-cadherin to induce desmosome formation and epidermoid phenotype. They also suggest a role for Pg as one of the regulators of the intracellular beta-catenin levels and underscore the pivotal role of this protein in regulating cell adhesion and differentiation.

Blood, 2002

Platelets undergo a series of actin-dependent morphologic changes when activated by thrombin rece... more Platelets undergo a series of actin-dependent morphologic changes when activated by thrombin receptor activating peptide (TRAP) or when spreading on glass. Polymerization of actin results in the sequential formation of filopodia, lamellipodia, and stress fibers, but the molecular mechanisms regulating this polymerization are unknown. The Arp2/3 complex nucleates actin polymerization in vitro and could perform this function inside cells as well. To test whether Arp2/3 regulated platelet actin polymerization, we used recombinant Arp2 protein (rArp2) to generate Arp2-specific antibodies (αArp2). Intact and Fab fragments of αArp2 inhibited TRAP-stimulated actin-polymerizing activity in platelet extracts as measured by the pyrene assay. Inhibition was reversed by the addition of rArp2 protein. To test the effect of Arp2/3 inhibition on the formation of specific actin structures, we designed a new method to permeabilize resting platelets while preserving their ability to adhere and to for...

Nature Communications, 2012

The recent discovery of high-temperature superconductivity in iron-based compounds has attracted ... more The recent discovery of high-temperature superconductivity in iron-based compounds has attracted much attention. How to further increase the superconducting transition temperature (T c) and how to understand the superconductivity mechanism are two prominent issues facing the current study of iron-based superconductors. The latest report of high-T c superconductivity in a single-layer FeSe is therefore both surprising and signifi cant. Here we present investigations of the electronic structure and superconducting gap of the single-layer FeSe superconductor. Its Fermi surface is distinct from other iron-based superconductors, consisting only of electron-like pockets near the zone corner without indication of any Fermi surface around the zone centre. Nearly isotropic superconducting gap is observed in this strictly two-dimensional system. The temperature dependence of the superconducting gap gives a transition temperature T c ~ 55 K. These results have established a clear case that such a simple electronic structure is compatible with high-T c superconductivity in iron-based superconductors.

财经与管理 =, Jun 22, 2020

The most basic idea of nancial technology is to use science and technology to promote greater inn... more The most basic idea of nancial technology is to use science and technology to promote greater innovation and breakthroughs in the nancial industry, in order to improve the competitiveness of nancial institutions themselves. According to the research, big data plat forms and smart cities are powerful guarantees that can maximize nancial reform and development. The paper analyzes the problems and application directions of urban big data platforms and nancial technology in nancial reform and development in detail. Taking a city in China as an example, the paper introduces its application of big data design information platform to provide people with more scienti c, accurate and convenient services.

Chinese Optics Letters, 2011

Nonlinear Analysis: Real World Applications, 2009

财经与管理, 2020

金融科技最基本的思路就是通过运用科学技术来促进金融行业有更大的创新突破，以此来提高金融机构自身的竞争实力。根据研究可知，大数据平台以及智慧城市是可以最大限度推动金融改革与发展的有力保障。论文针对... more 金融科技最基本的思路就是通过运用科学技术来促进金融行业有更大的创新突破，以此来提高金融机构自身的竞争实力。根据研究可知，大数据平台以及智慧城市是可以最大限度推动金融改革与发展的有力保障。论文针对城市大数据平台和金融科技在金融改革和发展中的问题、应用方向进行详细分析地。论文以中国某市为例，介绍了其应用大数据设计信息平台为人们提供更加科学、准确、便捷的服务。

Journal of Physics: Conference Series, 2021

The TiCN coatings were successfully prepared by means of reactive plasma with spraying self-made ... more The TiCN coatings were successfully prepared by means of reactive plasma with spraying self-made composite powder prepared from 150°C to 350°C in the paper. Sucrose was used as a carbon source, using the means of Precursor body carbon, sucrose and titanium powder mixing at high temperature after the heat treatment furnace for carbonization. Finally, the titanium powder was wrapped by the carbon, so the composite powder was mixed more uniform and could react more fully. TiCN coatings could not be synthesized with the composite powder prepared the temperatures of 150°C and 250°C, because the sucrose was not carbonized totally and could not carbonize to synthesize TiCN with Ti and N2 in the process of spraying. TiCN coatings were prepared by spraying the composite powder under heat treatment at 350°C and which composed of Ti and C at a ratio of 1:3. The phase compositions, the morphologies, the hardness and the microstructures were analyzed. The results showed that TiCN coating was con...

Archives of Biochemistry and Biophysics, 1998

completely prevented by coincubation of cells with ferricyanide or Tempol. The data in this study... more completely prevented by coincubation of cells with ferricyanide or Tempol. The data in this study suggest In addition to the broad repertoire of regulatory that nitroxyl may contribute to the cytotoxicity associfunctions nitric oxide (NO) serves in mammalian physated with an enhanced expression of the L-arginine:NO iology, the L-arginine:NO pathway is also involved in pathway under different biological conditions. ᭧ 1998 numerous pathophysiological mechanisms. While NO Academic Press itself may actually protect cells from the toxicity of reactive oxygen radicals in some cases, it has been suggested that reactive nitrogen oxide species formed from nitric oxide synthase (NOS) can be cytotoxic. In Nitric oxide (NO) has been postulated as a causative addition to NO, the one electron reduction product agent in a variety of pathophysiological states. How-NO 0 has been proposed to be formed from NOS. We ever, effects ascribed to NO are often mutually contrainvestigated the potential cytotoxic role of nitroxyl dictory and have therefore been a source of some confu-(NO 0), using the nitroxyl donor Angelis's salt, (AS; sosion (1). For instance, NO, in the presence of oxygen dium trioxodinitrate, Na 2 N 2 O 3) as the source of NO 0. or superoxide, can generate reactive nitrogen oxide spe-AS was found to be cytotoxic to Chinese hamster V79 cies (RNOS) 2 , which can oxidize nitrate, or nitrosate, lung fibroblast cells over a concentration range of 2-4 mM. The presence of equimolar ferricyanide (Fe(III)-other biomolecules (2, 3). RNOS are proposed to medi-(CN 6) 30), which converts NO 0 to NO, afforded dramatic ate various toxic and cytotoxic mechanisms. In conprotection against AS-mediated cytotoxicity. Treattrast, NO can protect cells from damage caused by reacment of V79 cells with L-buthionine sulfoximine to retive oxygen species (ROS) (4-6), as a result of different duce intracellular glutathione markedly enhanced AS chemical reactions than those involving RNOS (7-10). cytotoxicity, which suggests that GSH is critical for NO participates in chemical reactions associated cellular protection against the toxicity of NO 0. Furwith both oxidative and nitrosative stress which can ther experiments showed that low molecular weight have deleterious consequences in vivo. Studies suggest transition metal complexes associated with the formathat there exists a balance between NO and two of tion of reactive oxygen species are not involved in ASthe major reactive nitrogen oxide species, dinitrogen mediated cytotoxicity since metal chelators had no eftrioxide (N 2 O 3) and peroxynitrite (ONOO 0) (11-13) fect. However, under aerobic conditions, AS was more that can determine the toxicological outcome under toxic than under hypoxic conditions, suggesting that oxygen dramatically enhanced AS-mediated cytotoxicity. At a molecular level, AS exposure resulted in DNA

Journal of Physics: Conference Series, 2020

Combination of the load-bearing conditions, the tower shape and service time, and the geological ... more Combination of the load-bearing conditions, the tower shape and service time, and the geological and basic conditions of the service environment of the tower, various factors that influence the stability of the towering tower near goaf were classified by using fuzzy comprehensive evaluation method and AHP, and the influence factor model was established. The impact factors were evaluated from low to high, the influence of the geological and basic conditions of the service environment is maximal, and determined the approximate rock roadway is stable and no measures need to take to improve the stability of the tower.

Journal of Biological Chemistry, 1997

The Journal of organic chemistry, Jan 7, 2014

This paper describes the synthesis and systematic study of substituted acenes that have differenc... more This paper describes the synthesis and systematic study of substituted acenes that have differences in conjugation both along their long axes (by the number of fused benzene or thiophene rings) and along their short axes (by the number of arylethynyl substituents). These acenes include what we believe to be the first reported examples of five new subclasses of substituted acenes. Systematic analyses of data obtained using absorbance and fluorescence spectroscopies, cyclic voltammetry, and DFT calculations reveal clear correlations between these common structural perturbations to acene structure and the key parameters, such as HOMO-LUMO gap, frontier molecular orbital energies, and reactivity with singlet oxygen.

Journal of Film and Video, 2005

A JAZZ MUSICIAN, FRED MADISON (BILL PULL MAN), catches on to the fact that his wife, Renee (Patri... more A JAZZ MUSICIAN, FRED MADISON (BILL PULL MAN), catches on to the fact that his wife, Renee (Patricia Arquette), is having an affair. Fred is anxiety-ridden and cannot sleep; he's heading for a psychotic breakdown, which fi nally happens at a party when the Mystery Man ...

High penetration of renewable energy source makes microgrid (MGs) be environment friendly. Howeve... more High penetration of renewable energy source makes microgrid (MGs) be environment friendly. However, the stochastic input from renewable energy resource brings difficulty in balancing the energy supply and demand. Purchasing extra energy from macrogrid to deal with energy shortage will increase MG energy cost. To mitigate intermittent nature of renewable energy, energy trading and energy storage which can exploit diversity of renewable energy generation across space and time are efficient and cost-effective methods. But a storage with large capacity will incur additional cost. In addition, due to MG participating energy trading as prosumer, it calls for an efficient trading mechanism. Therefore, this paper focuses on the problem of MG energy management and trading. Energy trading problem is formulated as a stochastic optimization one with both individual profit and social welfare maximization. Firstly a Lyapunov optimization based algorithm is developed to solve the stochastic problem. Secondly the double-auction based mechanism is provided to attract MGs' truthful bidding for buying and selling energy. Through theoretical analysis, we demonstrate that individual MG can achieve a time average energy cost close to offline optimum with tradeoff between storage capacity and energy trading cost. Meanwhile the social welfare is also asymptotically maximized under double auction. Simulation results based on real world data show the effectiveness of our algorithm.

2018 International Conference on Power System Technology (POWERCON), 2018

Along with the development of UHV technology, an extra-large-scaled AC / DC hybrid power grid has... more Along with the development of UHV technology, an extra-large-scaled AC / DC hybrid power grid has been accomplished in China, the characteristics of the power system is facing profound changes, the techs of simulations are needed to be improved as well to meet the new requirements. The electromagnetic transient simulation is often used to model DC system to obtain more accurate dynamic characteristics. However, the operation status adjustment and initialization process of the EMT model of DC systems seriously affect the efficiency in simulation of AC/DC power grids. In this paper, a method of auto-initializing the electromagnetic model of DC transmission is proposed. Using the AC/DC large-scale network power flow as the boundary condition, the internal power flow solution of the DC electromagnetic model is quickly calculated, and the initial on-valves, the position of converter transformer’s tap, the AC filters’ switching scheme, and the control instructions are accurately determined. This solution enables the automatic initialization of the UHVDC electromagnetic model so that it can reach a predetermined steady state during the 0.5 s simulation. The method proposed in this paper realizes the fast and smooth start-up of the electromechanical-electromagnetic transient hybrid simulation with a large number of electromagnetic UHVDC models, and solves the application problems of the electromechanical-electromagnetic transient hybrid simulation in operation mode calculation and online simulation of power grid.

JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, a... more JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact

arXiv (Cornell University), Feb 9, 2017

High penetration of renewable energy source makes microgrid (MGs) be environment friendly. Howeve... more High penetration of renewable energy source makes microgrid (MGs) be environment friendly. However, the stochastic input from renewable energy resource brings difficulty in balancing the energy supply and demand. Purchasing extra energy from macrogrid to deal with energy shortage will increase MG energy cost. To mitigate intermittent nature of renewable energy, energy trading and energy storage which can exploit diversity of renewable energy generation across space and time are efficient and cost-effective methods. But current energy storage control action will impact the future control action which brings challenge to energy management. In addition, due to MG participating energy trading as prosumer, it calls for an efficient trading mechanism. Therefore, this paper focuses on the problem of MG energy management and trading. Energy trading problem is formulated as a stochastic optimization one with both individual profit and social welfare maximization. Firstly a Lyapunov optimization based algorithm is developed to solve the stochastic problem. Secondly the double-auction based mechanism is provided to attract MGs' truthful bidding for buying and selling energy. Through theoretical analysis, we demonstrate that individual MG can achieve a time average energy cost close to offline optimum with tradeoff between storage capacity and energy trading cost. Meanwhile the social welfare is also asymptotically maximized under double auction. Simulation results based on real world data show the effectiveness of our algorithm.

Bacteria come in a variety of shapes. While the peptidoglycan (PG) cell wall serves as an exoskel... more Bacteria come in a variety of shapes. While the peptidoglycan (PG) cell wall serves as an exoskeleton that defines the static cell shape, the internal bacterial cytoskeleton mediates cell shape by recruiting PG synthesis machinery and thus defining the pattern of cell-wall synthesis. While much is known about the chemistry and biology of the cytoskeleton and cell wall, much of their biophysics, including essential aspects of the functionality, dynamics, and organization, remain unknown. This dissertation aims to elucidate the detailed biophysical mechanisms of cytoskeleton guided wall synthesis. First, I find that the bacterial cytoskeleton MreB contributes nearly as much to the rigidity of an Escherichia coli cell as the cell wall. This conclusion implies that the cytoskeletal polymer MreB applies meaningful force to the cell wall, an idea favored by theoretical modeling of wall growth, and suggests an evolutionary origin of cytoskeleton-governed cell rigidity. Second, I observe that MreB rotates around the long axis of E. coli, and the motion depends on wall synthesis. This is the first discovery of a cell-wall assembly driven molecular motor in bacteria. Third, I prove that both cell-wall synthesis and the PG network have chiral ordering, which is established by the spatial pattern of MreB. This work links the molecular structure of the cytoskeleton and of the cell wall with organismal-scale behavior. Finally, I develop a mathematical model of cytoskeleton-cell membrane interactions, which explains the preferential orientation of different cytoskeleton components in bacteria.

Cell Motility and the Cytoskeleton, 1998

Pg is a homologue of beta-catenin and Armadillo, the product of the Drosophila segment polarity g... more Pg is a homologue of beta-catenin and Armadillo, the product of the Drosophila segment polarity gene and has been shown to have both adhesive and signaling functions. It interacts with both classic and desmosomal cadherins. Pg interaction with the desmosomal cadherins is essential for desmosome assembly. Its precise role in the classic cadherin complexes is unclear, although Pg-E-cadherin interaction appears to be necessary for the formation of desmosomes. In addition to cadherins in adhesion complexes, Pg interacts with a number of proteins involved in regulation of cell differentiation and proliferation such as Lef-1/Tcf-1 transcription factors and the tumor suppressor protein APC. In this study, we have introduced Pg cDNA into SCC9 cells, a Pg- and E-cadherin-deficient squamous cell carcinoma line, which also lacks desmosomes. These cells have both alpha-catenin and beta-catenin, display unusual expression of N-cadherin, and have the typical fibroblastic phenotype of transformed cells. Pg-expressing SCC9 cells (SCC9P) formed desmosomes. Desmosome formation coincided with the appearance of an epidermoid phenotype, with increased adhesiveness and a contact-dependent decrease in growth. Biochemical characterization of SCC9P cells showed an increase in the expression and stability of N-cadherin and a decrease in level and stability of beta-catenin, without any apparent effects on alpha-catenin. These results show that, in the absence of E-cadherin, Pg can efficiently use N-cadherin to induce desmosome formation and epidermoid phenotype. They also suggest a role for Pg as one of the regulators of the intracellular beta-catenin levels and underscore the pivotal role of this protein in regulating cell adhesion and differentiation.

Blood, 2002

Platelets undergo a series of actin-dependent morphologic changes when activated by thrombin rece... more Platelets undergo a series of actin-dependent morphologic changes when activated by thrombin receptor activating peptide (TRAP) or when spreading on glass. Polymerization of actin results in the sequential formation of filopodia, lamellipodia, and stress fibers, but the molecular mechanisms regulating this polymerization are unknown. The Arp2/3 complex nucleates actin polymerization in vitro and could perform this function inside cells as well. To test whether Arp2/3 regulated platelet actin polymerization, we used recombinant Arp2 protein (rArp2) to generate Arp2-specific antibodies (αArp2). Intact and Fab fragments of αArp2 inhibited TRAP-stimulated actin-polymerizing activity in platelet extracts as measured by the pyrene assay. Inhibition was reversed by the addition of rArp2 protein. To test the effect of Arp2/3 inhibition on the formation of specific actin structures, we designed a new method to permeabilize resting platelets while preserving their ability to adhere and to for...

Nature Communications, 2012

The recent discovery of high-temperature superconductivity in iron-based compounds has attracted ... more The recent discovery of high-temperature superconductivity in iron-based compounds has attracted much attention. How to further increase the superconducting transition temperature (T c) and how to understand the superconductivity mechanism are two prominent issues facing the current study of iron-based superconductors. The latest report of high-T c superconductivity in a single-layer FeSe is therefore both surprising and signifi cant. Here we present investigations of the electronic structure and superconducting gap of the single-layer FeSe superconductor. Its Fermi surface is distinct from other iron-based superconductors, consisting only of electron-like pockets near the zone corner without indication of any Fermi surface around the zone centre. Nearly isotropic superconducting gap is observed in this strictly two-dimensional system. The temperature dependence of the superconducting gap gives a transition temperature T c ~ 55 K. These results have established a clear case that such a simple electronic structure is compatible with high-T c superconductivity in iron-based superconductors.

财经与管理 =, Jun 22, 2020

The most basic idea of nancial technology is to use science and technology to promote greater inn... more The most basic idea of nancial technology is to use science and technology to promote greater innovation and breakthroughs in the nancial industry, in order to improve the competitiveness of nancial institutions themselves. According to the research, big data plat forms and smart cities are powerful guarantees that can maximize nancial reform and development. The paper analyzes the problems and application directions of urban big data platforms and nancial technology in nancial reform and development in detail. Taking a city in China as an example, the paper introduces its application of big data design information platform to provide people with more scienti c, accurate and convenient services.