Zita Bertasiene - Academia.edu (original) (raw)
Papers by Zita Bertasiene
Medicina (Kaunas, Lithuania), 2008
Exercise cardiography still remains the cornerstone of noninvasive evaluation of functional statu... more Exercise cardiography still remains the cornerstone of noninvasive evaluation of functional status of cardiovascular system and is almost uniformly performed after myocardial infarction. The patients after myocardial infarction can be divided into relative high- and low-risk groups for subsequent cardiac events if all information available on the exercise test is used. The aim of this study was to evaluate the prognostic significance of the shape of heart rate and systolic blood pressure curves (their dynamic characteristics) during the early exercise testing and after it and to design the prognostic system capable to recognize patients with a high risk of coronary death during 2 years after myocardial infarction. The submaximal exercise testing within 3 weeks of acute myocardial infarction was performed on 894 patients. Cases of noncardiac deaths or patients subjected to coronary bypass surgery were excluded from the further analysis. At the end of 2 years after myocardial infarcti...
Medicina (Kaunas, Lithuania), 2004
The aim of the study was to evaluate changes of ventricular repolarization variables during the e... more The aim of the study was to evaluate changes of ventricular repolarization variables during the exercise test in women with coronary heart disease, to determine variables, which can best predict significant coronary artery stenoses, and to improve noninvasive diagnostics of coronary heart disease. Ninety women with unstable angina pectoris undergone coronary artery angiography and exercise test on 4th-6th day of hospitalization at Kaunas University of Medicine Hospital. There was no difference in ventricular repolarization variables (JT interval, JT dispersion, JT and ST product) in women without coronary artery stenoses and those with one or two coronary artery stenoses. Sensitivity (87%), specificity (60%), positive predictive (43%), negative predictive (93%) and diagnostic value (67%) of stress test variable, which had no correlation with heart rate -ST and JT product- was greater comparing with ST depression greater than 0.1 mV (values respectively 61%, 49%, 29%, 79%, 52%). JT d...
Medicina (Kaunas, Lithuania), 2014
Beat-to-beat alteration in ventricles repolarization reflected by alternans of amplitude and/or s... more Beat-to-beat alteration in ventricles repolarization reflected by alternans of amplitude and/or shape of ECG S-T,T segment (TWA) is known as phenomena related with risk of severe arrhythmias leading to sudden cardiac death. Technical difficulties have caused limited its usage in clinical diagnostics. Possibilities to register and analyze multimodal signals reflecting heart activity inspired search for new technical solutions. First objective of this study was to test whether thoracic impedance signal and beat-to-beat heart rate reflect repolarization alternans detected as TWA. The second objective was revelation of multimodal signal features more comprehensively representing the phenomena and increasing its prognostic usefulness. ECG, and thoracic impedance signal recordings made during 24h follow-up of the patients hospitalized in acute phase of myocardial infarction were used for investigation. Signal morphology variations reflecting estimates were obtained by the principal compon...
International Journal of Cardiology, 2007
Methods: 135 coronary heart disease patients (pts), complicated by heart failure (HF) III-IY func... more Methods: 135 coronary heart disease patients (pts), complicated by heart failure (HF) III-IY functional class (FC) and pulmonary hypertension (PH) were surveyed. EchoCG, bicycle test, flow mediated dilation (FMD) of the brachial artery and circulating markers of endothelial function (EF) were collected. The 1st group was treated with nebivolol, the 2nd groupbisoprolol, and the 3rd groupeprosartan and bisoprolol during 6 months. Results: Systolic and diastolic function of LV, tolerance to physical exercise and life quality improved in the 1st group. Pulmonary artery systolic pressure (PASP) decreases in the moderate PH subgroup from 42.17 ± 5.1 to 31.7± 8.4 (p = 0.002) during 6 months. EF improvement was noted according to FMD and biochemical indices. Improvements in intracardiac haemodynamics and EF were noted in the 2nd group. PASP decreased in pts with moderate PH (from 40.4 ± 3.1 to 28.5 ± 8.5 mm Hg) (p =0.000); in the subgroup with expressed increase in PASP only the tendency to decrease in PH was noted. In the 3rd groupinitially 78% pts had expressed PH 48 ± 7.7 mm Hg. PASP decreased in pts with moderate PH (from 41.4 ± 2.1 mm Hg up to 29.7 ± 8.5 mm Hg (p = 0.032)) and in pts with expressed increase in PASP (from 52.4 ± 3.1 mm Hg to 37.6 ± 4.5 mm Hg (p = 0.04). Conclusions: If ACE inhibitors and BAB for treatment of HF with PH are used without effect, eprosartan can be used for decrease in PASP as part of a comprehensive therapy for HF. The important circumstance is that comprehensive therapy with bisoprolol and eprosartan is effective in pts with HF III-IY FC and with moderate and, what is particularly essential, with expressed pulmonary hypertension.
Medicina (Kaunas, Lithuania), 2008
Exercise cardiography still remains the cornerstone of noninvasive evaluation of functional statu... more Exercise cardiography still remains the cornerstone of noninvasive evaluation of functional status of cardiovascular system and is almost uniformly performed after myocardial infarction. The patients after myocardial infarction can be divided into relative high- and low-risk groups for subsequent cardiac events if all information available on the exercise test is used. The aim of this study was to evaluate the prognostic significance of the shape of heart rate and systolic blood pressure curves (their dynamic characteristics) during the early exercise testing and after it and to design the prognostic system capable to recognize patients with a high risk of coronary death during 2 years after myocardial infarction. The submaximal exercise testing within 3 weeks of acute myocardial infarction was performed on 894 patients. Cases of noncardiac deaths or patients subjected to coronary bypass surgery were excluded from the further analysis. At the end of 2 years after myocardial infarcti...
Medicina (Kaunas, Lithuania), 2004
The aim of the study was to evaluate changes of ventricular repolarization variables during the e... more The aim of the study was to evaluate changes of ventricular repolarization variables during the exercise test in women with coronary heart disease, to determine variables, which can best predict significant coronary artery stenoses, and to improve noninvasive diagnostics of coronary heart disease. Ninety women with unstable angina pectoris undergone coronary artery angiography and exercise test on 4th-6th day of hospitalization at Kaunas University of Medicine Hospital. There was no difference in ventricular repolarization variables (JT interval, JT dispersion, JT and ST product) in women without coronary artery stenoses and those with one or two coronary artery stenoses. Sensitivity (87%), specificity (60%), positive predictive (43%), negative predictive (93%) and diagnostic value (67%) of stress test variable, which had no correlation with heart rate -ST and JT product- was greater comparing with ST depression greater than 0.1 mV (values respectively 61%, 49%, 29%, 79%, 52%). JT d...
Medicina (Kaunas, Lithuania), 2014
Beat-to-beat alteration in ventricles repolarization reflected by alternans of amplitude and/or s... more Beat-to-beat alteration in ventricles repolarization reflected by alternans of amplitude and/or shape of ECG S-T,T segment (TWA) is known as phenomena related with risk of severe arrhythmias leading to sudden cardiac death. Technical difficulties have caused limited its usage in clinical diagnostics. Possibilities to register and analyze multimodal signals reflecting heart activity inspired search for new technical solutions. First objective of this study was to test whether thoracic impedance signal and beat-to-beat heart rate reflect repolarization alternans detected as TWA. The second objective was revelation of multimodal signal features more comprehensively representing the phenomena and increasing its prognostic usefulness. ECG, and thoracic impedance signal recordings made during 24h follow-up of the patients hospitalized in acute phase of myocardial infarction were used for investigation. Signal morphology variations reflecting estimates were obtained by the principal compon...
International Journal of Cardiology, 2007
Methods: 135 coronary heart disease patients (pts), complicated by heart failure (HF) III-IY func... more Methods: 135 coronary heart disease patients (pts), complicated by heart failure (HF) III-IY functional class (FC) and pulmonary hypertension (PH) were surveyed. EchoCG, bicycle test, flow mediated dilation (FMD) of the brachial artery and circulating markers of endothelial function (EF) were collected. The 1st group was treated with nebivolol, the 2nd groupbisoprolol, and the 3rd groupeprosartan and bisoprolol during 6 months. Results: Systolic and diastolic function of LV, tolerance to physical exercise and life quality improved in the 1st group. Pulmonary artery systolic pressure (PASP) decreases in the moderate PH subgroup from 42.17 ± 5.1 to 31.7± 8.4 (p = 0.002) during 6 months. EF improvement was noted according to FMD and biochemical indices. Improvements in intracardiac haemodynamics and EF were noted in the 2nd group. PASP decreased in pts with moderate PH (from 40.4 ± 3.1 to 28.5 ± 8.5 mm Hg) (p =0.000); in the subgroup with expressed increase in PASP only the tendency to decrease in PH was noted. In the 3rd groupinitially 78% pts had expressed PH 48 ± 7.7 mm Hg. PASP decreased in pts with moderate PH (from 41.4 ± 2.1 mm Hg up to 29.7 ± 8.5 mm Hg (p = 0.032)) and in pts with expressed increase in PASP (from 52.4 ± 3.1 mm Hg to 37.6 ± 4.5 mm Hg (p = 0.04). Conclusions: If ACE inhibitors and BAB for treatment of HF with PH are used without effect, eprosartan can be used for decrease in PASP as part of a comprehensive therapy for HF. The important circumstance is that comprehensive therapy with bisoprolol and eprosartan is effective in pts with HF III-IY FC and with moderate and, what is particularly essential, with expressed pulmonary hypertension.