Zung Tran - Academia.edu (original) (raw)

Papers by Zung Tran

Research paper thumbnail of Walking and Non-HDL-C: A Meta-Analysis of Randomized Controlled Trials

Med Sci Sport Exercise, 2004

Research paper thumbnail of Aerobic Exercise And Lipids And Lipoproteins In Women: A Meta-analysis Of Randomized Controlled Trials

Med Sci Sport Exercise, 2005

Background-Cardiovascular disease (CVD) in women is the leading cause of mortality in the United ... more Background-Cardiovascular disease (CVD) in women is the leading cause of mortality in the United States, and less than optimal lipid and lipoprotein levels are major risk factors for CVD. The purpose of this study was to use the meta-analytic approach to examine the effects of aerobic exercise on lipids and lipoproteins in women.

Research paper thumbnail of Estimating Sample Size in Repeated-Measures Analysis of Variance

Measurement in Physical Education and Exercise Science, Nov 18, 2009

Research paper thumbnail of Effects of Exercise Training on Serum Lipid and Lipoprotein Levels in Post-MI Patients: A Meta-analysis

Journal of Cardiopulmonary Rehabilitation, 1989

It has been suggested that regular exercise produces favorable changes in serum lipid and lipopro... more It has been suggested that regular exercise produces favorable changes in serum lipid and lipoprotein-cholesterol concentrations. However, most of the subjects in this area of research have been men. Given the differences in lipid profiles between men and women, we wanted to determine if these same favorable changes took place in women. Of the 145 longitudinal studies available in this area, 27 met the criteria for inclusion in this analysis (i.e., an exercise training study that used women subjects and measured changes in lipid concentrations). Results show that exercise does favorably alter serum lipid profiles in women by reducing total cholesterol (194 to 190 mg.dl-1; P = 0.02), triglyceride (91 to 82 mg.dl-1; P = 0.01), and the ratio of total cholesterol to high-density lipoprotein-cholesterol (3.28 to 3.16; mg.dl-1; P = 0.03). However, a significant increase in high-density lipoprotein-cholesterol or decrease in low-density lipoprotein-cholesterol concentration was not observed. Results also show that changes in body weight during exercise are associated with changes in total cholesterol (r = 0.56; P = 0.01) and triglyceride (r = 0.42; P = 0.06) concentrations, indicating that greater body weight losses resulted in larger decreases in cholesterol and triglyceride concentrations. Further analysis indicates that those women most at risk for heart disease (elevated pre-exercise cholesterol concentrations) responded most favorably to exercise training. These results suggest that exercise training, especially for those at risk for heart diseases is beneficial to the lipid profile of women.

Research paper thumbnail of The Bootstrap: Verifying Mean Changes in Cholesterol from Resistive Exercise 1114

Med Sci Sport Exercise, 1996

Research paper thumbnail of Multivariate Analysis of Exercise and Changes in Serum Lipids and Lipoproteins: A Meta-Analysis

Med Sci Sport Exercise, 1984

Research paper thumbnail of 489 Gender Related Results of an Aerobic Field Test for Selection of Fire Fighters

Med Sci Sport Exercise, 1994

Research paper thumbnail of Injectable Multiple Sclerosis Medications

International Journal of MS Care, 2012

avoidance of sensitive sites were the most frequently used strategies to minimize ISRs. These dat... more avoidance of sensitive sites were the most frequently used strategies to minimize ISRs. These data may help identify patients with characteristics associated with a higher risk for ISRs, allowing health-care professionals to provide anticipatory guidance to patients at risk for decreased adherence or discontinuation. Int J MS Care. 2012;14:46-53.

Research paper thumbnail of Treatment Regimens and Their Effectiveness: A Meta-Analytic Review of the Literature

Research paper thumbnail of Factors Related to Fatigue in Multiple Sclerosis

International Journal of MS Care, 2007

Research paper thumbnail of Retrieval of Individual Patient Data for an Exercise-Related Meta-Analysis

Med Sci Sport Exercise, 2002

Research paper thumbnail of Exercise and bone mineral density in men: a meta-analysis

Journal of Applied Physiology, May 1, 2000

[PDF] [Abstract] , July 1, 2009; 3 (4): 310-319. American Journal of Lifestyle Medicine S. B. Goi... more [PDF] [Abstract] , July 1, 2009; 3 (4): 310-319. American Journal of Lifestyle Medicine S. B. Going and M. Laudermilk Osteoporosis and Strength Training [PDF] [Full Text] [Abstract] , July 1, 2009; 1 (4): 341-346. Bone Health: Part 2, Physical Activity [PDF] [Full Text] [Abstract]

Research paper thumbnail of Aerobic exercise and normotensive adults: a meta-analysis

Medicine Amp Science in Sports Amp Exercise, Oct 1, 1995

Using the meta-analytic approach, the purpose of this study was to examine the effects of aerobic... more Using the meta-analytic approach, the purpose of this study was to examine the effects of aerobic exercise on resting systolic (SYS) and diastolic (DIA) blood pressure in normotensive adults: The results of 35 human clinical training studies published in English-language journals between 1963 and 1992 and representing 1,076 subjects (800 exercise, 276 control) met criteria for inclusion. Across all categories and designs, statistically significant post-exercise reductions were found for both SYS and DIA blood pressure (mean +/- SD, SYS: -4.4 +/- 6.6 mm Hg, 95% CI, -6.2 to -2.6 mm Hg; DIA: -3.2 +/- 3.2 mm Hg, 95% CI, -4.0 to -2.2 mm Hg). When partitioned according to type of study: 1) (randomized controlled trials (RCT), 2) controlled trials (CT), and 3) no controls (NC), the following changes were noted: RCT, SYS: -4.5 +/- 7.2 mm Hg, 95% CI, -7.1 to -1.2 mm Hg; DIA: -3.8 +/- 2.9 mm Hg, 95% CI, -5.0 to -2.6 mm Hg; CT, SYS: -2.8 +/- 6.9 mm Hg, 95% CI, -10.0 to 4.4 mm Hg; DIA: -5.0 +/- 3.7 mm Hg, 95% CI, -8.9 to -1.1 mm Hg; NC, SYS: -4.7 +/- 6.1 mm Hg, 95% CI, -7.5 to 1.9 mm Hg; DIA: -1.7 +/- 3.0 mm Hg, 95% CI, -3.2 to -0.36 mm Hg. We concluded that aerobic exercise results in small reductions in resting SYS and DIA blood pressure among normotensive adults.

Research paper thumbnail of Age-related declines in maximal aerobic capacity in regularly exercising vs. sedentary women: a meta-analysis

Journal of Applied Physiology, Jul 1, 1997

to Exercise? Differently Decline in VO2max More Rapid in Men and Do Older Men and Women Respond G... more to Exercise? Differently Decline in VO2max More Rapid in Men and Do Older Men and Women Respond Gender Differences in Cardiorespiratory Fitness With Advancing Age: Is the Age-Associated [PDF] [Full Text] [Abstract] , August 1, 2009; 15 (15): 4963-4967. Clin. Cancer Res. Adjuvant Trastuzumab Induces Ventricular Remodeling Despite Aerobic Exercise Training [PDF] [Full Text] [Abstract] , August 1, 2009; 587 (15): 3885-3897. arterioles Effects of ageing and exercise training on eNOS uncoupling in skeletal muscle resistance [PDF] [Full Text] , August 1, 2009; 107 (2): 377-378. J Appl Physiol C. R. Woodman Setting the "tone" for aging in the skeletal muscle microcirculation [PDF] [Full Text] [Abstract] , November 1, 2009; 54 (5): 1014-1020. Hypertension

Research paper thumbnail of Effects of Exercise Training on Serum Lipid and Lipoprotein Concentrations in Women: A Meta-Analysis

International Journal of Sports Medicine, 1989

It has been suggested that regular exercise produces favorable changes in serum lipid and lipopro... more It has been suggested that regular exercise produces favorable changes in serum lipid and lipoprotein-cholesterol concentrations. However, most of the subjects in this area of research have been men. Given the differences in lipid profiles between men and women, we wanted to determine if these same favorable changes took place in women. Of the 145 longitudinal studies available in this area, 27 met the criteria for inclusion in this analysis (i.e., an exercise training study that used women subjects and measured changes in lipid concentrations). Results show that exercise does favorably alter serum lipid profiles in women by reducing total cholesterol (194 to 190 mg.dl-1; P = 0.02), triglyceride (91 to 82 mg.dl-1; P = 0.01), and the ratio of total cholesterol to high-density lipoprotein-cholesterol (3.28 to 3.16; mg.dl-1; P = 0.03). However, a significant increase in high-density lipoprotein-cholesterol or decrease in low-density lipoprotein-cholesterol concentration was not observed. Results also show that changes in body weight during exercise are associated with changes in total cholesterol (r = 0.56; P = 0.01) and triglyceride (r = 0.42; P = 0.06) concentrations, indicating that greater body weight losses resulted in larger decreases in cholesterol and triglyceride concentrations. Further analysis indicates that those women most at risk for heart disease (elevated pre-exercise cholesterol concentrations) responded most favorably to exercise training. These results suggest that exercise training, especially for those at risk for heart diseases is beneficial to the lipid profile of women.

Research paper thumbnail of GLUTAMINE'S ATTENUATION OF NF-kB AND MORTALITY FOLLOWING SEPSIS ARE DEPENDENT ON HSP-70 EXPRESSION

Research paper thumbnail of Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials

Preventive Medicine, 2004

Background. The purpose of this study was to use the meta-analytic approach to examine the effect... more Background. The purpose of this study was to use the meta-analytic approach to examine the effects of walking on lipids and lipoproteins in adults.

Research paper thumbnail of Aerobic Exercise and Resting Blood Pressure: A Meta-Analytic Review of Randomized, Controlled Trials

Preventive Cardiology, 2001

In this study the authors used the meta-analytic approach to examine the effects of aerobic exerc... more In this study the authors used the meta-analytic approach to examine the effects of aerobic exercise on resting systolic and diastolic blood pressure in adults. Forty-seven clinical trials representing a total of 72 effect sizes in 2543 subjects (1653 exercise, 890 control) met the criteria for inclusion. Statistically significant exercise-minus-control decreases were found for changes in resting systolic and diastolic blood pressure in both hypertensive (systolic, -6 mm Hg, 95% CI, -8 to -3; diastolic, -5 mm Hg, 95% CI, -7 to -3) and normotensive (systolic, -2 mm Hg, 95% CI, -3 to -1; diastolic, -1 mm Hg, 95% CI, -2 to -1) groups. The differences between groups were statistically significant (systolic, p=0.008; diastolic, p=0.000). Relative decreases were approximately 4% (systolic) and 5% (diastolic) in hypertensives, and 2% (systolic) and 1% (diastolic) in normotensives. It was concluded that aerobic exercise reduces resting systolic and diastolic blood pressure in adults.

Research paper thumbnail of Original Metric vs. Standardized Effect Sizes for Meta-Analysis of Clinical Data

Preventive Cardiology, 2001

WINTER 2001 PREVENTIVE CARDIOLOGY 41

Research paper thumbnail of Walking and Non-HDL-C in Adults: A Meta-Analysis of Randomized Controlled Trials

Preventive Cardiology, 2005

An elevated level of non-high-density lipoprotein cholesterol (non-HDL-C) is a major risk factor ... more An elevated level of non-high-density lipoprotein cholesterol (non-HDL-C) is a major risk factor for cardiovascular disease. The purpose of this study was to use the meta-analytic approach to examine the effects of walking on non-HDL-C in adults. Twenty-two randomized controlled trials representing 30 outcomes from 948 subjects (573 exercise, 375 control) met our inclusion criteria. Across all designs and categories, random effects modeling resulted in a significantly greater decrease in the walking group when compared with the control group of approximately 4% for non-HDL-C (X̄ ± standard error of the mean, −5.6±1.8 mg/dL, 95% confidence interval, −8.8 to −2.4 mg/dL). Meta-regression showed a statistically significant association between changes in non-HDL-C and the year of publication, with greater reductions associated with more recent publication year (R 2 =0.23, p=0.005). The results of this meta-analytic review suggest that walking reduces non-HDL-C in adult humans.

Research paper thumbnail of Walking and Non-HDL-C: A Meta-Analysis of Randomized Controlled Trials

Med Sci Sport Exercise, 2004

Research paper thumbnail of Aerobic Exercise And Lipids And Lipoproteins In Women: A Meta-analysis Of Randomized Controlled Trials

Med Sci Sport Exercise, 2005

Background-Cardiovascular disease (CVD) in women is the leading cause of mortality in the United ... more Background-Cardiovascular disease (CVD) in women is the leading cause of mortality in the United States, and less than optimal lipid and lipoprotein levels are major risk factors for CVD. The purpose of this study was to use the meta-analytic approach to examine the effects of aerobic exercise on lipids and lipoproteins in women.

Research paper thumbnail of Estimating Sample Size in Repeated-Measures Analysis of Variance

Measurement in Physical Education and Exercise Science, Nov 18, 2009

Research paper thumbnail of Effects of Exercise Training on Serum Lipid and Lipoprotein Levels in Post-MI Patients: A Meta-analysis

Journal of Cardiopulmonary Rehabilitation, 1989

It has been suggested that regular exercise produces favorable changes in serum lipid and lipopro... more It has been suggested that regular exercise produces favorable changes in serum lipid and lipoprotein-cholesterol concentrations. However, most of the subjects in this area of research have been men. Given the differences in lipid profiles between men and women, we wanted to determine if these same favorable changes took place in women. Of the 145 longitudinal studies available in this area, 27 met the criteria for inclusion in this analysis (i.e., an exercise training study that used women subjects and measured changes in lipid concentrations). Results show that exercise does favorably alter serum lipid profiles in women by reducing total cholesterol (194 to 190 mg.dl-1; P = 0.02), triglyceride (91 to 82 mg.dl-1; P = 0.01), and the ratio of total cholesterol to high-density lipoprotein-cholesterol (3.28 to 3.16; mg.dl-1; P = 0.03). However, a significant increase in high-density lipoprotein-cholesterol or decrease in low-density lipoprotein-cholesterol concentration was not observed. Results also show that changes in body weight during exercise are associated with changes in total cholesterol (r = 0.56; P = 0.01) and triglyceride (r = 0.42; P = 0.06) concentrations, indicating that greater body weight losses resulted in larger decreases in cholesterol and triglyceride concentrations. Further analysis indicates that those women most at risk for heart disease (elevated pre-exercise cholesterol concentrations) responded most favorably to exercise training. These results suggest that exercise training, especially for those at risk for heart diseases is beneficial to the lipid profile of women.

Research paper thumbnail of The Bootstrap: Verifying Mean Changes in Cholesterol from Resistive Exercise 1114

Med Sci Sport Exercise, 1996

Research paper thumbnail of Multivariate Analysis of Exercise and Changes in Serum Lipids and Lipoproteins: A Meta-Analysis

Med Sci Sport Exercise, 1984

Research paper thumbnail of 489 Gender Related Results of an Aerobic Field Test for Selection of Fire Fighters

Med Sci Sport Exercise, 1994

Research paper thumbnail of Injectable Multiple Sclerosis Medications

International Journal of MS Care, 2012

avoidance of sensitive sites were the most frequently used strategies to minimize ISRs. These dat... more avoidance of sensitive sites were the most frequently used strategies to minimize ISRs. These data may help identify patients with characteristics associated with a higher risk for ISRs, allowing health-care professionals to provide anticipatory guidance to patients at risk for decreased adherence or discontinuation. Int J MS Care. 2012;14:46-53.

Research paper thumbnail of Treatment Regimens and Their Effectiveness: A Meta-Analytic Review of the Literature

Research paper thumbnail of Factors Related to Fatigue in Multiple Sclerosis

International Journal of MS Care, 2007

Research paper thumbnail of Retrieval of Individual Patient Data for an Exercise-Related Meta-Analysis

Med Sci Sport Exercise, 2002

Research paper thumbnail of Exercise and bone mineral density in men: a meta-analysis

Journal of Applied Physiology, May 1, 2000

[PDF] [Abstract] , July 1, 2009; 3 (4): 310-319. American Journal of Lifestyle Medicine S. B. Goi... more [PDF] [Abstract] , July 1, 2009; 3 (4): 310-319. American Journal of Lifestyle Medicine S. B. Going and M. Laudermilk Osteoporosis and Strength Training [PDF] [Full Text] [Abstract] , July 1, 2009; 1 (4): 341-346. Bone Health: Part 2, Physical Activity [PDF] [Full Text] [Abstract]

Research paper thumbnail of Aerobic exercise and normotensive adults: a meta-analysis

Medicine Amp Science in Sports Amp Exercise, Oct 1, 1995

Using the meta-analytic approach, the purpose of this study was to examine the effects of aerobic... more Using the meta-analytic approach, the purpose of this study was to examine the effects of aerobic exercise on resting systolic (SYS) and diastolic (DIA) blood pressure in normotensive adults: The results of 35 human clinical training studies published in English-language journals between 1963 and 1992 and representing 1,076 subjects (800 exercise, 276 control) met criteria for inclusion. Across all categories and designs, statistically significant post-exercise reductions were found for both SYS and DIA blood pressure (mean +/- SD, SYS: -4.4 +/- 6.6 mm Hg, 95% CI, -6.2 to -2.6 mm Hg; DIA: -3.2 +/- 3.2 mm Hg, 95% CI, -4.0 to -2.2 mm Hg). When partitioned according to type of study: 1) (randomized controlled trials (RCT), 2) controlled trials (CT), and 3) no controls (NC), the following changes were noted: RCT, SYS: -4.5 +/- 7.2 mm Hg, 95% CI, -7.1 to -1.2 mm Hg; DIA: -3.8 +/- 2.9 mm Hg, 95% CI, -5.0 to -2.6 mm Hg; CT, SYS: -2.8 +/- 6.9 mm Hg, 95% CI, -10.0 to 4.4 mm Hg; DIA: -5.0 +/- 3.7 mm Hg, 95% CI, -8.9 to -1.1 mm Hg; NC, SYS: -4.7 +/- 6.1 mm Hg, 95% CI, -7.5 to 1.9 mm Hg; DIA: -1.7 +/- 3.0 mm Hg, 95% CI, -3.2 to -0.36 mm Hg. We concluded that aerobic exercise results in small reductions in resting SYS and DIA blood pressure among normotensive adults.

Research paper thumbnail of Age-related declines in maximal aerobic capacity in regularly exercising vs. sedentary women: a meta-analysis

Journal of Applied Physiology, Jul 1, 1997

to Exercise? Differently Decline in VO2max More Rapid in Men and Do Older Men and Women Respond G... more to Exercise? Differently Decline in VO2max More Rapid in Men and Do Older Men and Women Respond Gender Differences in Cardiorespiratory Fitness With Advancing Age: Is the Age-Associated [PDF] [Full Text] [Abstract] , August 1, 2009; 15 (15): 4963-4967. Clin. Cancer Res. Adjuvant Trastuzumab Induces Ventricular Remodeling Despite Aerobic Exercise Training [PDF] [Full Text] [Abstract] , August 1, 2009; 587 (15): 3885-3897. arterioles Effects of ageing and exercise training on eNOS uncoupling in skeletal muscle resistance [PDF] [Full Text] , August 1, 2009; 107 (2): 377-378. J Appl Physiol C. R. Woodman Setting the "tone" for aging in the skeletal muscle microcirculation [PDF] [Full Text] [Abstract] , November 1, 2009; 54 (5): 1014-1020. Hypertension

Research paper thumbnail of Effects of Exercise Training on Serum Lipid and Lipoprotein Concentrations in Women: A Meta-Analysis

International Journal of Sports Medicine, 1989

It has been suggested that regular exercise produces favorable changes in serum lipid and lipopro... more It has been suggested that regular exercise produces favorable changes in serum lipid and lipoprotein-cholesterol concentrations. However, most of the subjects in this area of research have been men. Given the differences in lipid profiles between men and women, we wanted to determine if these same favorable changes took place in women. Of the 145 longitudinal studies available in this area, 27 met the criteria for inclusion in this analysis (i.e., an exercise training study that used women subjects and measured changes in lipid concentrations). Results show that exercise does favorably alter serum lipid profiles in women by reducing total cholesterol (194 to 190 mg.dl-1; P = 0.02), triglyceride (91 to 82 mg.dl-1; P = 0.01), and the ratio of total cholesterol to high-density lipoprotein-cholesterol (3.28 to 3.16; mg.dl-1; P = 0.03). However, a significant increase in high-density lipoprotein-cholesterol or decrease in low-density lipoprotein-cholesterol concentration was not observed. Results also show that changes in body weight during exercise are associated with changes in total cholesterol (r = 0.56; P = 0.01) and triglyceride (r = 0.42; P = 0.06) concentrations, indicating that greater body weight losses resulted in larger decreases in cholesterol and triglyceride concentrations. Further analysis indicates that those women most at risk for heart disease (elevated pre-exercise cholesterol concentrations) responded most favorably to exercise training. These results suggest that exercise training, especially for those at risk for heart diseases is beneficial to the lipid profile of women.

Research paper thumbnail of GLUTAMINE'S ATTENUATION OF NF-kB AND MORTALITY FOLLOWING SEPSIS ARE DEPENDENT ON HSP-70 EXPRESSION

Research paper thumbnail of Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials

Preventive Medicine, 2004

Background. The purpose of this study was to use the meta-analytic approach to examine the effect... more Background. The purpose of this study was to use the meta-analytic approach to examine the effects of walking on lipids and lipoproteins in adults.

Research paper thumbnail of Aerobic Exercise and Resting Blood Pressure: A Meta-Analytic Review of Randomized, Controlled Trials

Preventive Cardiology, 2001

In this study the authors used the meta-analytic approach to examine the effects of aerobic exerc... more In this study the authors used the meta-analytic approach to examine the effects of aerobic exercise on resting systolic and diastolic blood pressure in adults. Forty-seven clinical trials representing a total of 72 effect sizes in 2543 subjects (1653 exercise, 890 control) met the criteria for inclusion. Statistically significant exercise-minus-control decreases were found for changes in resting systolic and diastolic blood pressure in both hypertensive (systolic, -6 mm Hg, 95% CI, -8 to -3; diastolic, -5 mm Hg, 95% CI, -7 to -3) and normotensive (systolic, -2 mm Hg, 95% CI, -3 to -1; diastolic, -1 mm Hg, 95% CI, -2 to -1) groups. The differences between groups were statistically significant (systolic, p=0.008; diastolic, p=0.000). Relative decreases were approximately 4% (systolic) and 5% (diastolic) in hypertensives, and 2% (systolic) and 1% (diastolic) in normotensives. It was concluded that aerobic exercise reduces resting systolic and diastolic blood pressure in adults.

Research paper thumbnail of Original Metric vs. Standardized Effect Sizes for Meta-Analysis of Clinical Data

Preventive Cardiology, 2001

WINTER 2001 PREVENTIVE CARDIOLOGY 41

Research paper thumbnail of Walking and Non-HDL-C in Adults: A Meta-Analysis of Randomized Controlled Trials

Preventive Cardiology, 2005

An elevated level of non-high-density lipoprotein cholesterol (non-HDL-C) is a major risk factor ... more An elevated level of non-high-density lipoprotein cholesterol (non-HDL-C) is a major risk factor for cardiovascular disease. The purpose of this study was to use the meta-analytic approach to examine the effects of walking on non-HDL-C in adults. Twenty-two randomized controlled trials representing 30 outcomes from 948 subjects (573 exercise, 375 control) met our inclusion criteria. Across all designs and categories, random effects modeling resulted in a significantly greater decrease in the walking group when compared with the control group of approximately 4% for non-HDL-C (X̄ ± standard error of the mean, −5.6±1.8 mg/dL, 95% confidence interval, −8.8 to −2.4 mg/dL). Meta-regression showed a statistically significant association between changes in non-HDL-C and the year of publication, with greater reductions associated with more recent publication year (R 2 =0.23, p=0.005). The results of this meta-analytic review suggest that walking reduces non-HDL-C in adult humans.