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Research paper thumbnail of Plasmodium falciparum isolate with histidine-rich protein 2 gene deletion from Nyala City, Western Sudan

Scientific Reports, 2020

In remote areas of malaria-endemic countries, rapid diagnostic tests (RDTs) have dramatically imp... more In remote areas of malaria-endemic countries, rapid diagnostic tests (RDTs) have dramatically improved parasitological confirmation of suspected malaria cases, especially when skilled microscopists are not available. This study was designed to determine the frequency of Plasmodium falciparum isolates with histidine-rich protein 2 (pfhrp2) gene deletion as one of the possible factors contributing to the failure of PfHRP2-based RDTs in detecting malaria. A total of 300 blood samples were collected from several health centres in Nyala City, Western Sudan. The performance of PfHRP2-based RDTs in relation to microscopy was examined and the PCR-confirmed samples were investigated for the presence of pfhrp2 gene. A total of 113 out of 300 patients were P. falciparum positive by microscopy. Among them, 93.81% (106 out of 113) were positives by the PfHRP2 RDTs. Seven isolates were identified as false negative on the basis of the RDTs results. Only one isolate (0.9%; 1/113) potentially has pf...

Research paper thumbnail of Emergence of Undetectable Malaria Parasites: A Threat under the Radar amid the COVID-19 Pandemic?

The American Journal of Tropical Medicine and Hygiene, 2020

Research paper thumbnail of Development of a slurry continuous flow reactor for photocatalytic treatment of industrial waste water

Journal of Photochemistry and Photobiology A: Chemistry, 2010

The water treatment capability of a novel photocatalytic slurry reactor was investigated using me... more The water treatment capability of a novel photocatalytic slurry reactor was investigated using methylene blue (MB) as a model pollutant in an aqueous suspension. A pellet TiO 2 catalyst was employed and this freed the system from the need of filtration of catalyst following ...

Research paper thumbnail of Plasmodium falciparum isolate with histidine-rich protein 2 gene deletion from Nyala City, Western Sudan

Scientific Reports, 2020

In remote areas of malaria-endemic countries, rapid diagnostic tests (RDTs) have dramatically imp... more In remote areas of malaria-endemic countries, rapid diagnostic tests (RDTs) have dramatically improved parasitological confirmation of suspected malaria cases, especially when skilled microscopists are not available. This study was designed to determine the frequency of Plasmodium falciparum isolates with histidine-rich protein 2 (pfhrp2) gene deletion as one of the possible factors contributing to the failure of PfHRP2-based RDTs in detecting malaria. A total of 300 blood samples were collected from several health centres in Nyala City, Western Sudan. The performance of PfHRP2-based RDTs in relation to microscopy was examined and the PCR-confirmed samples were investigated for the presence of pfhrp2 gene. A total of 113 out of 300 patients were P. falciparum positive by microscopy. Among them, 93.81% (106 out of 113) were positives by the PfHRP2 RDTs. Seven isolates were identified as false negative on the basis of the RDTs results. Only one isolate (0.9%; 1/113) potentially has pf...

Research paper thumbnail of Emergence of Undetectable Malaria Parasites: A Threat under the Radar amid the COVID-19 Pandemic?

The American Journal of Tropical Medicine and Hygiene, 2020

Research paper thumbnail of Development of a slurry continuous flow reactor for photocatalytic treatment of industrial waste water

Journal of Photochemistry and Photobiology A: Chemistry, 2010

The water treatment capability of a novel photocatalytic slurry reactor was investigated using me... more The water treatment capability of a novel photocatalytic slurry reactor was investigated using methylene blue (MB) as a model pollutant in an aqueous suspension. A pellet TiO 2 catalyst was employed and this freed the system from the need of filtration of catalyst following ...

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