akmal jamal - Academia.edu (original) (raw)

Papers by akmal jamal

Research paper thumbnail of General Surgery an Experience with Total Stripping of Great Saphenous Vein in the Management of Varicose Veins

OBJECTIVE: To determine the efficacy of complete GSV stripping in terms of morbidity, nerve injur... more OBJECTIVE: To determine the efficacy of complete GSV stripping in terms of morbidity, nerve injury and recurrence rates. METHODS: 42 patients with uncomplicated unilateral and/or bilateral varicosities involving the great saphenous system were included in this study. Patients with primary and/or recurrent varicose veins associated with active or healed ulcers, patients with bleeding diathesis and those who failed to sign the proforma for regular follow-ups were excluded from this study. Complete stripping of great saphenous vein up to the ankle, together with multiple phlebectomies was performed in all patients. Postoperatively, limbs were examined for complications like bruising, edema, wound site infections and sensory abnormalities. All the patients were followed up for the period of one year for recurrence and improvement in sensory abnormalities. RESULTS: All the patients belonged to CEAP class 2 or greater. The mean age of patients in this series was 33 years (range 20-48 year...

Research paper thumbnail of Tetanus Situation in Pakistan

The Professional Medical Journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight var... more Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight various management strategies as well as the outcome of the tetanus patients.Background: Tetanus, a preventable disease still found in high frequency in developing world.Globally one million cases are recorded annually. This disease found more frequently in patientswho are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made onclinical grounds with no definitive investigation available to confirm the diagnosis. Mortality ofTetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptiveobservational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period:1st Nov 2008 to 31st Oct 2015. Materials & methods: It includes patients of either sex abovethe age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected forvariables related to demography, incubation period, site of injury, hist...

Research paper thumbnail of Tetanus Situation in Pakistan; Comparison of Medical Versus Surgical Management

The professional medical journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight va... more Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight various management strategies as well as the outcome of the tetanus patients. Background: Tetanus, a preventable disease still found in high frequency in developing world. Globally one million cases are recorded annually. This disease found more frequently in patients who are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made on clinical grounds with no definitive investigation available to confirm the diagnosis. Mortality of Tetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptive observational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period: 1st Nov 2008 to 31 st Oct 2015. Materials & methods: It includes patients of either sex above the age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected for variables related to demography, incubation period, site of i...

Research paper thumbnail of Tetanus Situation in Pakistan

The Professional Medical Journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight var... more Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight various management strategies as well as the outcome of the tetanus patients.Background: Tetanus, a preventable disease still found in high frequency in developing world.Globally one million cases are recorded annually. This disease found more frequently in patientswho are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made onclinical grounds with no definitive investigation available to confirm the diagnosis. Mortality ofTetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptiveobservational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period:1st Nov 2008 to 31st Oct 2015. Materials & methods: It includes patients of either sex abovethe age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected forvariables related to demography, incubation period, site of injury, hist...

Research paper thumbnail of Analysis of 200 Cases of Tube Thoracostomies Performed by General Surgeons

OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: ... more OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: Prospective, descriptive study. PLACE &DURATION OF STUDY: Public and private sector hospitals of Nawabshah and Hyderabad from 1st Jan 2005 to Dec 2008. METHODOLOGY: All patients of either sex above the age of 13 years having pathology related to chest cavity and underwent chest intubation were included in the study. Patients below the age of 13 years, having serious co morbid illness like Ischemic heart disease (ASA-3), severe chronic obstructive airway disease requiring ventilator support, and complicated chronic liver disease & patients who lost to follow-up were excluded. Data was collected for age, sex, indications of chest intubations, cause of the disease, procedural and post procedural complications & hospital stay. Descriptive analysis was performed using SPSS version 10 for continuous and frequency variables. RESULTS: Total 200 patients of different pathologies related to chest ...

Research paper thumbnail of Tetanus Situation in Pakistan; Comparison of Medical Versus Surgical Management

The professional medical journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight va... more Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight various management strategies as well as the outcome of the tetanus patients. Background: Tetanus, a preventable disease still found in high frequency in developing world. Globally one million cases are recorded annually. This disease found more frequently in patients who are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made on clinical grounds with no definitive investigation available to confirm the diagnosis. Mortality of Tetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptive observational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period: 1st Nov 2008 to 31 st Oct 2015. Materials & methods: It includes patients of either sex above the age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected for variables related to demography, incubation period, site of i...

Research paper thumbnail of Analysis of 200 Cases of Tube Thoracostomies Performed by General Surgeons

OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: ... more OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: Prospective, descriptive study. PLACE &DURATION OF STUDY: Public and private sector hospitals of Nawabshah and Hyderabad from 1st Jan 2005 to Dec 2008. METHODOLOGY: All patients of either sex above the age of 13 years having pathology related to chest cavity and underwent chest intubation were included in the study. Patients below the age of 13 years, having serious co morbid illness like Ischemic heart disease (ASA-3), severe chronic obstructive airway disease requiring ventilator support, and complicated chronic liver disease & patients who lost to follow-up were excluded. Data was collected for age, sex, indications of chest intubations, cause of the disease, procedural and post procedural complications & hospital stay. Descriptive analysis was performed using SPSS version 10 for continuous and frequency variables. RESULTS: Total 200 patients of different pathologies related to chest ...

Research paper thumbnail of Deep Venous Thrombosis

The Professional Medical Journal, 2016

Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-... more Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-Dimmer and Doppler sonography. Study Design: Case control study.Place and Duration: Department of Surgery, Liaquat University of Medical and Health SciencesJamshoro/Hyderabad from May 2013 to April 2014. Subjects and Methods: A sampleof 106 subjects; 50 controls and 53 diagnosed patients of DVT were studied. DVT patientswere included according to inclusion and exclusion criteria and after results of Sonographyand D-Dimer were available. The Blood samples were collected in bottles containing sodiumcitrate as anticoagulant. MPV was generated by Sysmex KX 21 hematology analyzer. Informedconsent was sought from the volunteer subjects. The Data was analyzed using SPSS version21.0. Statistically significance was defined at p-value of ≤0.05. Results: Mean plateletvolume was elevated in deep venous thrombosis patients which were confirmed by clinicalexamination, sonography and D-Dimer. MPV was e...

Research paper thumbnail of Deep Venous Thrombosis

The Professional Medical Journal, 2016

Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-... more Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-Dimmer and Doppler sonography. Study Design: Case control study.Place and Duration: Department of Surgery, Liaquat University of Medical and Health SciencesJamshoro/Hyderabad from May 2013 to April 2014. Subjects and Methods: A sampleof 106 subjects; 50 controls and 53 diagnosed patients of DVT were studied. DVT patientswere included according to inclusion and exclusion criteria and after results of Sonographyand D-Dimer were available. The Blood samples were collected in bottles containing sodiumcitrate as anticoagulant. MPV was generated by Sysmex KX 21 hematology analyzer. Informedconsent was sought from the volunteer subjects. The Data was analyzed using SPSS version21.0. Statistically significance was defined at p-value of ≤0.05. Results: Mean plateletvolume was elevated in deep venous thrombosis patients which were confirmed by clinicalexamination, sonography and D-Dimer. MPV was e...

Research paper thumbnail of Frequency of Hodgkin's Lymphoma in Patient with Cervical Lymphadenopathy Presenting in a Public Sector Hospital in Pakistan

Journal of Liaquat University of Medical & Health Sciences, 2008

and to see its pathological variants. STUDY DESIGN: Case series. STUDY SETTING: Surgical departme... more and to see its pathological variants. STUDY DESIGN: Case series. STUDY SETTING: Surgical departments of Liaquat University Hospital. STUDY DURATION: Five years from January 2000 to December 2004. SAMPLING: Non-probable purposive. INCLUSION CRITERIA: All patients of cervical lymph node enlargement of more than four weeks duration irrespective of age and sex. EXCLUSION CRITERIA: Cervical lymph node less than 1cm. STUDY VARIABLES: Study variables used were age, sex, symptom, clinical finding, stage and histopathology. DATA ANALYSIS: Data analysis was done by using SPSS version 10. RESULTS: A total of 500 patients with enlarged cervical lymph nodes were studied, amongst them 40 (8%) patients were diagnosed with Hodgkin's lymphoma (32 males and 8 females). Mean age of 40 patients was 23 years (range 9-44 years). Out of these 40 patients, in 8 (20%) patients it was difficult to differentiate lymphoma clinically from tuberculosis on clinical examination. Cervical swelling was the commonest symptom (100%) while fever, night sweats and weight-loss were present in 45% patients, 55% of patients were in stage III & IV (advance disease). Mixed cellularity was the commonest histological variant. All 40 patients after diagnosis and staging were referred to Nuclear Institute of Medical Radiotherapy for further management. CONCLUSION: Although tuberculous cervical lymph node enlargement is very common, but Hodgkin's lymphoma has a definite possibility of occurrence (8% in our study). Therefore all patients with enlarged cervical lymph node should not be treated with anti-tuberculosis therapy on empirical basis. Diagnosis should be confirmed by biopsy, otherwise patients may land up with advanced stage of Hodgkin's lymphoma with poor prognosis.

Research paper thumbnail of Randomized, Clinical Trial on Diathermy and Scalpel Incisions in Elective General Surgery

Iranian Red Crescent Medical Journal, 2015

Research paper thumbnail of Surface selection, adhesion, and retention behavior of marine bacteria on synthetic organic surfaces using self-assembled monolayers and atomic force microscopy

Ocean Dynamics, 2009

Um breve olhar na história da humanidade mostra que, mesmo que primitivo, em tempos remotos já ex... more Um breve olhar na história da humanidade mostra que, mesmo que primitivo, em tempos remotos já existia um certo sistema regulador de ações, exercido geralmente pela comunidade. Através da história, passando pelo poder da Igreja, dos reis e imperadores, o poder de punir (corrigir) é delegado, hoje, no Brasil ao Estado. Não obstante ao elevado grau de atualidade da legislação brasileira com relação ao meio ambiente, muitas são as dúvidas que os operadores da lei têm encontrado ao analisar os casos nessa área. De fato, a complexidade desse assunto passa, também, pela questão social e econômica indo desembocar, em muitos casos, na produção agrícola ou nas profundezas de um lençol freático, por exemplo. Entretanto, não é o próprio meio ambiente o destino final daquilo que denominamos de contaminação, senão o próprio homem. Se de um lado o ciclo de um contaminante parece claro, o próprio homem não pode ser considerado somente como um ser biológico, mas, sem dúvida é um ser social e psicológico. Não bastará à lei manter o homem biologicamente vivo, se este não tiver vida social e psicológica. É necessário, portanto, que a legislação ambiental ao ser aplicada, seja trabalhada na sua complexidade, ou seja, realmente envolvendo lei e meio ambiente, sendo o meio ambiente o homem na sua plenitude, e não somente o homem ou o meio ambiente. Na atual organização social brasileira, o interesse coletivo tem se expandido sobre os interesses individuais, em uma relação de responsabilidade e sanção. Com esta preocupação, o

Research paper thumbnail of Microfabrication of Patterns of Adherent Marine Bacterium Phaeobacter inhibens Using Soft Lithography and Scanning Probe Lithography

Langmuir, 2010

Two lithographic approaches have been explored for the microfabrication of cellular patterns base... more Two lithographic approaches have been explored for the microfabrication of cellular patterns based on the attachment of marine bacterium Phaeobacter inhibens strain T5. Strain T5 produces a new antibiotic that makes this bacterium potentially interesting for the pharmaceutical market and as a probiotic organism in aquacultures and in controlling biofouling. The microcontact printing (microCP) method is based on the micropatterning of self-assembled monolayers (SAMs) terminated with adhesive end groups such as CH(3) and COOH and nonadhesive groups (e.g., short oligomers of ethylene glycol (OEG)) to form micropatterned substrates for the adhesion of strain T5. The scanning probe lithographic method is based on the surface modification of OEG SAM by using a microelectrode, the probe of a scanning electrochemical microscope (SECM). Oxidizing agents (e.g., Br(2)) were electrogenerated in situ at the microelectrodes from Br(-) in aqueous solution to remove OEG SAMs locally, which allows the subsequent adsorption of bacteria. Various micropatterns of bacteria could be formed in situ on the substrate without a prefabricated template. The fabricated cellular patterns may be applied to a variety of marine biological studies that require the analysis of biofilm formation, cell-cell and cell-surface interactions, and cell-based biosensors and bioelectronics.

Research paper thumbnail of Inkjet-Printed Thiol Self-Assembled Monolayer Structures on Gold: Quality Control and Microarray Electrode Fabrication

Langmuir, 2008

Laterally structured, self-assembled monolayers (SAMs) of different thiols (HS-R-X, R = (CH 2) 3-... more Laterally structured, self-assembled monolayers (SAMs) of different thiols (HS-R-X, R = (CH 2) 3-16, X = -CH 3, -COOH, -NH 2) on gold have been prepared by inkjet printing. The printer is a modified, low-cost desktop printer (Epson Stylus Photo R200), the ink is a 1 mM solution of the thiol in ethanol/glycerol (6:1). The quality of inkjet-printed large area SAMs obtained in this study is between that of a layer self-assembled from a thiol solution and that obtained by soft lithography, according to cyclic voltammetry, electrochemical impedance spectroscopy, scanning electrochemical microscopy (SECM), and polarization-modulated Fourier transform infrared reflection-absorption spectroscopy (PM IRRAS). For the first time, simultaneous printing of two different thiols in a single print job as an alternative to sequential printing and backfilling is demonstrated. The smallest structures consisting of conductive disks of 40 microm diameter were analyzed as single spots by SECM and as random array electrodes with different average disk-disk distance. Conductive band electrodes with variable bandwidth (300 microm to 1 cm) are presented, as well as a pH switchable band structure. As compared to stamping, inkjet printing allows for simultaneous multiple thiol printing in a single print job with the resolution limited only by the droplet size and the precision of the translation stage.

Research paper thumbnail of Pilonidal Sinus: Excision with Primary Midline Closure versus Open Method

JLUMHS, 2010

... Tech Coloproctol 2002;6(3):165-9. 11. Mohamed HA, Kadry I, Adly S. Comparison be-tween three ... more ... Tech Coloproctol 2002;6(3):165-9. 11. Mohamed HA, Kadry I, Adly S. Comparison be-tween three therapeutic modalities for non compli-cated pilonidal sinus disease. ... 11 Shahida Khatoon, Afzal Junejo, Munir Memon, Muhammad Arif, Akmal Jamal, Noshad Ahmed Shaikh ...

Research paper thumbnail of Digital Simulation of Scanning Electrochemical Microscopy Approach Curves to Enzyme Films with Michaelis−Menten Kinetics

Analytical Chemistry, 2009

Research paper thumbnail of Open excision with secondary healing versus rhomboid excision with Limberg transposition flap in the management of sacrococcygeal pilonidal disease

JOURNAL OF PAKISTAN MEDICAL ASSOCIATION, 2009

To compare the outcome of Open excision and secondary healing with rhomboid excision and Limberg ... more To compare the outcome of Open excision and secondary healing with rhomboid excision and Limberg flap in the management of sacrococcygeal pilonidal sinus disease (SPD). A prospective, analytical, comparative study using randomized controlled trial (RCT) was conducted at Liaquat University Hospital (Jamshoro) & Fatima Hospital-Baqai Medical University (Karachi), from June 2004 to July 2007. In total 49 patients, who either underwent open excision and secondary healing (group A: 25 patients) or rhomboid excision and Limberg flap (group B: 24 patients), were enrolled in the study. Duration of operation, postoperative pain, duration of hospital stay, postoperative complications, and time to recurrence were noted. The inclusion criteria were all patients with primary or recurrent SPD. The exclusion criteria were: cases with incomplete data and those lost to follow-up. Duration of operation was longer in group B patients (p = 0.004) but pain perception was markedly reduced in this group (...

Research paper thumbnail of General Surgery an Experience with Total Stripping of Great Saphenous Vein in the Management of Varicose Veins

OBJECTIVE: To determine the efficacy of complete GSV stripping in terms of morbidity, nerve injur... more OBJECTIVE: To determine the efficacy of complete GSV stripping in terms of morbidity, nerve injury and recurrence rates. METHODS: 42 patients with uncomplicated unilateral and/or bilateral varicosities involving the great saphenous system were included in this study. Patients with primary and/or recurrent varicose veins associated with active or healed ulcers, patients with bleeding diathesis and those who failed to sign the proforma for regular follow-ups were excluded from this study. Complete stripping of great saphenous vein up to the ankle, together with multiple phlebectomies was performed in all patients. Postoperatively, limbs were examined for complications like bruising, edema, wound site infections and sensory abnormalities. All the patients were followed up for the period of one year for recurrence and improvement in sensory abnormalities. RESULTS: All the patients belonged to CEAP class 2 or greater. The mean age of patients in this series was 33 years (range 20-48 year...

Research paper thumbnail of Tetanus Situation in Pakistan

The Professional Medical Journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight var... more Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight various management strategies as well as the outcome of the tetanus patients.Background: Tetanus, a preventable disease still found in high frequency in developing world.Globally one million cases are recorded annually. This disease found more frequently in patientswho are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made onclinical grounds with no definitive investigation available to confirm the diagnosis. Mortality ofTetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptiveobservational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period:1st Nov 2008 to 31st Oct 2015. Materials & methods: It includes patients of either sex abovethe age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected forvariables related to demography, incubation period, site of injury, hist...

Research paper thumbnail of Tetanus Situation in Pakistan; Comparison of Medical Versus Surgical Management

The professional medical journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight va... more Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight various management strategies as well as the outcome of the tetanus patients. Background: Tetanus, a preventable disease still found in high frequency in developing world. Globally one million cases are recorded annually. This disease found more frequently in patients who are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made on clinical grounds with no definitive investigation available to confirm the diagnosis. Mortality of Tetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptive observational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period: 1st Nov 2008 to 31 st Oct 2015. Materials & methods: It includes patients of either sex above the age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected for variables related to demography, incubation period, site of i...

Research paper thumbnail of Tetanus Situation in Pakistan

The Professional Medical Journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight var... more Objectives: To determine demographic and clinical profile of Tetanus patientsand to highlight various management strategies as well as the outcome of the tetanus patients.Background: Tetanus, a preventable disease still found in high frequency in developing world.Globally one million cases are recorded annually. This disease found more frequently in patientswho are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made onclinical grounds with no definitive investigation available to confirm the diagnosis. Mortality ofTetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptiveobservational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period:1st Nov 2008 to 31st Oct 2015. Materials & methods: It includes patients of either sex abovethe age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected forvariables related to demography, incubation period, site of injury, hist...

Research paper thumbnail of Analysis of 200 Cases of Tube Thoracostomies Performed by General Surgeons

OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: ... more OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: Prospective, descriptive study. PLACE &DURATION OF STUDY: Public and private sector hospitals of Nawabshah and Hyderabad from 1st Jan 2005 to Dec 2008. METHODOLOGY: All patients of either sex above the age of 13 years having pathology related to chest cavity and underwent chest intubation were included in the study. Patients below the age of 13 years, having serious co morbid illness like Ischemic heart disease (ASA-3), severe chronic obstructive airway disease requiring ventilator support, and complicated chronic liver disease & patients who lost to follow-up were excluded. Data was collected for age, sex, indications of chest intubations, cause of the disease, procedural and post procedural complications & hospital stay. Descriptive analysis was performed using SPSS version 10 for continuous and frequency variables. RESULTS: Total 200 patients of different pathologies related to chest ...

Research paper thumbnail of Tetanus Situation in Pakistan; Comparison of Medical Versus Surgical Management

The professional medical journal, 2016

Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight va... more Objectives: To determine demographic and clinical profile of Tetanus patients and to highlight various management strategies as well as the outcome of the tetanus patients. Background: Tetanus, a preventable disease still found in high frequency in developing world. Globally one million cases are recorded annually. This disease found more frequently in patients who are either non vaccinated or partially immunized. Diagnosis of Tetanus is solely made on clinical grounds with no definitive investigation available to confirm the diagnosis. Mortality of Tetanus is directly related to the grade of tetanus at presentation. Study Design: Descriptive observational study. Setting: Public and private sector hospitals of Hyderabad, Pakistan. Period: 1st Nov 2008 to 31 st Oct 2015. Materials & methods: It includes patients of either sex above the age of 13 years who were clinically diagnosed as case of Tetanus. Data was collected for variables related to demography, incubation period, site of i...

Research paper thumbnail of Analysis of 200 Cases of Tube Thoracostomies Performed by General Surgeons

OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: ... more OBJECTIVE OF STUDY: To observe various indications & complications of tube Thoracostomy. DESIGN: Prospective, descriptive study. PLACE &DURATION OF STUDY: Public and private sector hospitals of Nawabshah and Hyderabad from 1st Jan 2005 to Dec 2008. METHODOLOGY: All patients of either sex above the age of 13 years having pathology related to chest cavity and underwent chest intubation were included in the study. Patients below the age of 13 years, having serious co morbid illness like Ischemic heart disease (ASA-3), severe chronic obstructive airway disease requiring ventilator support, and complicated chronic liver disease & patients who lost to follow-up were excluded. Data was collected for age, sex, indications of chest intubations, cause of the disease, procedural and post procedural complications & hospital stay. Descriptive analysis was performed using SPSS version 10 for continuous and frequency variables. RESULTS: Total 200 patients of different pathologies related to chest ...

Research paper thumbnail of Deep Venous Thrombosis

The Professional Medical Journal, 2016

Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-... more Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-Dimmer and Doppler sonography. Study Design: Case control study.Place and Duration: Department of Surgery, Liaquat University of Medical and Health SciencesJamshoro/Hyderabad from May 2013 to April 2014. Subjects and Methods: A sampleof 106 subjects; 50 controls and 53 diagnosed patients of DVT were studied. DVT patientswere included according to inclusion and exclusion criteria and after results of Sonographyand D-Dimer were available. The Blood samples were collected in bottles containing sodiumcitrate as anticoagulant. MPV was generated by Sysmex KX 21 hematology analyzer. Informedconsent was sought from the volunteer subjects. The Data was analyzed using SPSS version21.0. Statistically significance was defined at p-value of ≤0.05. Results: Mean plateletvolume was elevated in deep venous thrombosis patients which were confirmed by clinicalexamination, sonography and D-Dimer. MPV was e...

Research paper thumbnail of Deep Venous Thrombosis

The Professional Medical Journal, 2016

Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-... more Objectives: To study mean platelet volume (MPV) in deep venous thrombosis(DVT) as evaluated by D-Dimmer and Doppler sonography. Study Design: Case control study.Place and Duration: Department of Surgery, Liaquat University of Medical and Health SciencesJamshoro/Hyderabad from May 2013 to April 2014. Subjects and Methods: A sampleof 106 subjects; 50 controls and 53 diagnosed patients of DVT were studied. DVT patientswere included according to inclusion and exclusion criteria and after results of Sonographyand D-Dimer were available. The Blood samples were collected in bottles containing sodiumcitrate as anticoagulant. MPV was generated by Sysmex KX 21 hematology analyzer. Informedconsent was sought from the volunteer subjects. The Data was analyzed using SPSS version21.0. Statistically significance was defined at p-value of ≤0.05. Results: Mean plateletvolume was elevated in deep venous thrombosis patients which were confirmed by clinicalexamination, sonography and D-Dimer. MPV was e...

Research paper thumbnail of Frequency of Hodgkin's Lymphoma in Patient with Cervical Lymphadenopathy Presenting in a Public Sector Hospital in Pakistan

Journal of Liaquat University of Medical & Health Sciences, 2008

and to see its pathological variants. STUDY DESIGN: Case series. STUDY SETTING: Surgical departme... more and to see its pathological variants. STUDY DESIGN: Case series. STUDY SETTING: Surgical departments of Liaquat University Hospital. STUDY DURATION: Five years from January 2000 to December 2004. SAMPLING: Non-probable purposive. INCLUSION CRITERIA: All patients of cervical lymph node enlargement of more than four weeks duration irrespective of age and sex. EXCLUSION CRITERIA: Cervical lymph node less than 1cm. STUDY VARIABLES: Study variables used were age, sex, symptom, clinical finding, stage and histopathology. DATA ANALYSIS: Data analysis was done by using SPSS version 10. RESULTS: A total of 500 patients with enlarged cervical lymph nodes were studied, amongst them 40 (8%) patients were diagnosed with Hodgkin's lymphoma (32 males and 8 females). Mean age of 40 patients was 23 years (range 9-44 years). Out of these 40 patients, in 8 (20%) patients it was difficult to differentiate lymphoma clinically from tuberculosis on clinical examination. Cervical swelling was the commonest symptom (100%) while fever, night sweats and weight-loss were present in 45% patients, 55% of patients were in stage III & IV (advance disease). Mixed cellularity was the commonest histological variant. All 40 patients after diagnosis and staging were referred to Nuclear Institute of Medical Radiotherapy for further management. CONCLUSION: Although tuberculous cervical lymph node enlargement is very common, but Hodgkin's lymphoma has a definite possibility of occurrence (8% in our study). Therefore all patients with enlarged cervical lymph node should not be treated with anti-tuberculosis therapy on empirical basis. Diagnosis should be confirmed by biopsy, otherwise patients may land up with advanced stage of Hodgkin's lymphoma with poor prognosis.

Research paper thumbnail of Randomized, Clinical Trial on Diathermy and Scalpel Incisions in Elective General Surgery

Iranian Red Crescent Medical Journal, 2015

Research paper thumbnail of Surface selection, adhesion, and retention behavior of marine bacteria on synthetic organic surfaces using self-assembled monolayers and atomic force microscopy

Ocean Dynamics, 2009

Um breve olhar na história da humanidade mostra que, mesmo que primitivo, em tempos remotos já ex... more Um breve olhar na história da humanidade mostra que, mesmo que primitivo, em tempos remotos já existia um certo sistema regulador de ações, exercido geralmente pela comunidade. Através da história, passando pelo poder da Igreja, dos reis e imperadores, o poder de punir (corrigir) é delegado, hoje, no Brasil ao Estado. Não obstante ao elevado grau de atualidade da legislação brasileira com relação ao meio ambiente, muitas são as dúvidas que os operadores da lei têm encontrado ao analisar os casos nessa área. De fato, a complexidade desse assunto passa, também, pela questão social e econômica indo desembocar, em muitos casos, na produção agrícola ou nas profundezas de um lençol freático, por exemplo. Entretanto, não é o próprio meio ambiente o destino final daquilo que denominamos de contaminação, senão o próprio homem. Se de um lado o ciclo de um contaminante parece claro, o próprio homem não pode ser considerado somente como um ser biológico, mas, sem dúvida é um ser social e psicológico. Não bastará à lei manter o homem biologicamente vivo, se este não tiver vida social e psicológica. É necessário, portanto, que a legislação ambiental ao ser aplicada, seja trabalhada na sua complexidade, ou seja, realmente envolvendo lei e meio ambiente, sendo o meio ambiente o homem na sua plenitude, e não somente o homem ou o meio ambiente. Na atual organização social brasileira, o interesse coletivo tem se expandido sobre os interesses individuais, em uma relação de responsabilidade e sanção. Com esta preocupação, o

Research paper thumbnail of Microfabrication of Patterns of Adherent Marine Bacterium Phaeobacter inhibens Using Soft Lithography and Scanning Probe Lithography

Langmuir, 2010

Two lithographic approaches have been explored for the microfabrication of cellular patterns base... more Two lithographic approaches have been explored for the microfabrication of cellular patterns based on the attachment of marine bacterium Phaeobacter inhibens strain T5. Strain T5 produces a new antibiotic that makes this bacterium potentially interesting for the pharmaceutical market and as a probiotic organism in aquacultures and in controlling biofouling. The microcontact printing (microCP) method is based on the micropatterning of self-assembled monolayers (SAMs) terminated with adhesive end groups such as CH(3) and COOH and nonadhesive groups (e.g., short oligomers of ethylene glycol (OEG)) to form micropatterned substrates for the adhesion of strain T5. The scanning probe lithographic method is based on the surface modification of OEG SAM by using a microelectrode, the probe of a scanning electrochemical microscope (SECM). Oxidizing agents (e.g., Br(2)) were electrogenerated in situ at the microelectrodes from Br(-) in aqueous solution to remove OEG SAMs locally, which allows the subsequent adsorption of bacteria. Various micropatterns of bacteria could be formed in situ on the substrate without a prefabricated template. The fabricated cellular patterns may be applied to a variety of marine biological studies that require the analysis of biofilm formation, cell-cell and cell-surface interactions, and cell-based biosensors and bioelectronics.

Research paper thumbnail of Inkjet-Printed Thiol Self-Assembled Monolayer Structures on Gold: Quality Control and Microarray Electrode Fabrication

Langmuir, 2008

Laterally structured, self-assembled monolayers (SAMs) of different thiols (HS-R-X, R = (CH 2) 3-... more Laterally structured, self-assembled monolayers (SAMs) of different thiols (HS-R-X, R = (CH 2) 3-16, X = -CH 3, -COOH, -NH 2) on gold have been prepared by inkjet printing. The printer is a modified, low-cost desktop printer (Epson Stylus Photo R200), the ink is a 1 mM solution of the thiol in ethanol/glycerol (6:1). The quality of inkjet-printed large area SAMs obtained in this study is between that of a layer self-assembled from a thiol solution and that obtained by soft lithography, according to cyclic voltammetry, electrochemical impedance spectroscopy, scanning electrochemical microscopy (SECM), and polarization-modulated Fourier transform infrared reflection-absorption spectroscopy (PM IRRAS). For the first time, simultaneous printing of two different thiols in a single print job as an alternative to sequential printing and backfilling is demonstrated. The smallest structures consisting of conductive disks of 40 microm diameter were analyzed as single spots by SECM and as random array electrodes with different average disk-disk distance. Conductive band electrodes with variable bandwidth (300 microm to 1 cm) are presented, as well as a pH switchable band structure. As compared to stamping, inkjet printing allows for simultaneous multiple thiol printing in a single print job with the resolution limited only by the droplet size and the precision of the translation stage.

Research paper thumbnail of Pilonidal Sinus: Excision with Primary Midline Closure versus Open Method

JLUMHS, 2010

... Tech Coloproctol 2002;6(3):165-9. 11. Mohamed HA, Kadry I, Adly S. Comparison be-tween three ... more ... Tech Coloproctol 2002;6(3):165-9. 11. Mohamed HA, Kadry I, Adly S. Comparison be-tween three therapeutic modalities for non compli-cated pilonidal sinus disease. ... 11 Shahida Khatoon, Afzal Junejo, Munir Memon, Muhammad Arif, Akmal Jamal, Noshad Ahmed Shaikh ...

Research paper thumbnail of Digital Simulation of Scanning Electrochemical Microscopy Approach Curves to Enzyme Films with Michaelis−Menten Kinetics

Analytical Chemistry, 2009

Research paper thumbnail of Open excision with secondary healing versus rhomboid excision with Limberg transposition flap in the management of sacrococcygeal pilonidal disease

JOURNAL OF PAKISTAN MEDICAL ASSOCIATION, 2009

To compare the outcome of Open excision and secondary healing with rhomboid excision and Limberg ... more To compare the outcome of Open excision and secondary healing with rhomboid excision and Limberg flap in the management of sacrococcygeal pilonidal sinus disease (SPD). A prospective, analytical, comparative study using randomized controlled trial (RCT) was conducted at Liaquat University Hospital (Jamshoro) & Fatima Hospital-Baqai Medical University (Karachi), from June 2004 to July 2007. In total 49 patients, who either underwent open excision and secondary healing (group A: 25 patients) or rhomboid excision and Limberg flap (group B: 24 patients), were enrolled in the study. Duration of operation, postoperative pain, duration of hospital stay, postoperative complications, and time to recurrence were noted. The inclusion criteria were all patients with primary or recurrent SPD. The exclusion criteria were: cases with incomplete data and those lost to follow-up. Duration of operation was longer in group B patients (p = 0.004) but pain perception was markedly reduced in this group (...