akshay dhobley - Academia.edu (original) (raw)

Papers by akshay dhobley

Journal of Optics, Dec 21, 2023

Journal of Maxillofacial and Oral Surgery

Journal of Oral and Maxillofacial Pathology, 2011

Odontoameloblastoma (OA) is an extremely rare mixed odontogenic tumor with both epithelial and me... more Odontoameloblastoma (OA) is an extremely rare mixed odontogenic tumor with both epithelial and mesenchymal components. OA develops from proliferating odontogenic epithelium and mesenchymal tissue. Till date, around 20 cases have fulfilled the histologic criteria of the current World Health Organization (WHO) histologic classification of odontogenic tumors. It affects predominantly young patients with a median age of 20.12 years, and has a predilection for males and occurs in posterior segments of either jaw with slight inclination for mandible. Review of literature shows only three reported cases in the anterior mandible. Here, we report a case of OA in the anterior mandible.

IJID regions, Dec 1, 2022

Journal of Oral and Maxillofacial Pathology, 2013

Granular cell tumor (GCT) is a benign lesion characterized by the accumulation of plump cells wit... more Granular cell tumor (GCT) is a benign lesion characterized by the accumulation of plump cells with abundant granular cytoplasm. The formation of a granular cell tumor is a neoplastic process and the lesions formed are of neural derivation, as supported by immunophenotypic and ultra structural evidence. This type of tumor has been found to be both benign and malignant although malignancy is rare and comprises only 2% of all granular cell tumors. Here we report a case of GCT in a 40 year old male patient on the posterolateral border of tongue.

Journal of Dental and Allied Sciences, 2012

The exploration of new methods and techniques for the diagnosis of malignant tumours has always a... more The exploration of new methods and techniques for the diagnosis of malignant tumours has always attracted the attention of scientists. The development of adjunct tools to facilitate the non invasive screening of high risk lesions in real time has the potential to significantly improve our ability to reduce the dismal morbidity and mortality of oral cancer. Despite easy accessibility of the oral cavity to examination, there is no satisfactory method to adequately screen and detect precancers non-invasively. The current method of oral cancer diagnosis clinically relies heavily on visual examination of the oral cavity. However, discerning potentially malignant and early malignant lesions from common benign inflammatory conditions can be difficult at times. There is a need for an objective method that could provide real-time results and be routinely applied to a large population. Though science is yet to present such a perfect technique, Optical Biopsy Systems developed using knowledge of light and tissue interaction, can provide a plausible option.

Oral and Maxillofacial Surgery, Jul 31, 2012

Neoplasms of peripheral nerve in the head and neck region are of common occurrence, but origin in... more Neoplasms of peripheral nerve in the head and neck region are of common occurrence, but origin in the oral and para-oral tissues is uncommon and they rarely occur centrally within the jaws. Schwannoma is a benign neoplasm originating from the neural sheath of peripheral soft tissues, but its occurrence within the jaw bones is most unusual. Plexiform schwannoma is a unique variant of Schwann cell tumours having plexiform pattern. Literature revealed only one case of plexiform schwannoma of the jaw bones, i.e. involving the mandible. In this report, we present the first documented case of intraosseous plexiform schwannoma of the maxilla, an extremely rare benign neurogenic tumour treated surgically. Schwannoma is a benign neoplasm originating from the neural sheath of peripheral soft tissues, but to occur within the jaw bones is exceptional. Plexiform schwannoma is a rare variant of Schwann cell tumour having plexiform pattern of intraneural growth with multinodularity. Plexiform schwannoma is a benign neoplasm with no malignant potential, but recurrences are evident if excised incompletely. Plexiform schwannoma has similar clinical and histopathological features as that of plexiform neurofibroma which has high malignant potential; hence, it is imperative to correctly diagnose and differentiate this lesion as treatment modality of these two lesions differs.

Journal of Medicine, Radiology, Pathology and Surgery, 2016

Pharmaceutical Development and Technology

Journal of Precision Oncology

International journal of pharma and bio sciences, 2015

The cruciferae, Brassicaceae family, are characterized by the presence of a group of secondary me... more The cruciferae, Brassicaceae family, are characterized by the presence of a group of secondary metabolites called glucosinolates. More than 30 glucosinolates are present in the Brassica species. They are hydrolyzed by the enzyme myrosinase. Their breakdown products are chemically very reactive, and for a long time been known for their bioactive characteristics, such as anticarcinogenic, fungicidal or bactericidal properties. However, there is little information available about its toxicity profile. The present study was undertaken to investigate the potential toxic effects of methanolic extracts of Brassica oleracea L.var capitata (cabbage) in vivo. The toxic effects of extracts of Brassica oleracea were evaluated at different doses of hot soxhlet and cold macerated extracts. Alteration in SGOT, SGPT and ALP levels in a dose and concentration dependent manner was observed there by portraying its therapeutic and toxic concentrations.

Cureus

SARS coronavirus2 is the primary cause of new Coronavirus illness (COVID-19) (SARS-COV-2). Today,... more SARS coronavirus2 is the primary cause of new Coronavirus illness (COVID-19) (SARS-COV-2). Today, COVID-19 is a global epidemic. Coronavirus illness may be diagnosed using a variety of approaches. The gold standard is RT-PCR, which is used in all of these assays. Swabs from the nose, pharynx, or mouth are the most often used sampling methods for coronavirus detection. For COVID-19 testing, saliva may be utilized as an alternate sample. When compared to a nasopharyngeal swab, saliva samples have a number of advantages and disadvantages. Saliva has also been reviewed as a non-invasive diagnostic tool for the detection of COVID-19. The affordability of the salivary diagnostic process makes it an effective process for detecting the COVID-19 viruses. The researchers have found that salivary diagnostic processes have greater chances of success than other processes of Coronavirus detection. However, healthcare professionals need to make positive changes to their working processes to ensure the sustainability of the salivary diagnosis processes.

Annals of the Romanian Society for Cell Biology, Apr 12, 2021

American Journal of Public Health, 1999

OBJECTIVES: This study investigated dentists refusal to treat patients who have HIV. METHODS: A s... more OBJECTIVES: This study investigated dentists refusal to treat patients who have HIV. METHODS: A survey was mailed to a random sample of all licensed dentists in Canada, with 3 follow-up attempts (n = 6444). Data were weighted to allow for probability of selection and nonresponse and analyzed with Pearson's chi 2 and multiple logistic regression. RESULTS: The response rate was 66%. Of the respondents, 32% had knowingly treated HIV-infected patients in the last year; 16% would refuse to treat HIV-infected patients. Respondents reported willingness to treat HIV-infected patients (81%), injection drug users (86%), hepatitis B virus-infected patients (87%), homosexual and bisexual persons (94%), individuals with sexually transmitted disease(s) (94%), and recipients of blood and blood products (97%). The best predictors of refusal to treat patients with HIV were lack of ethical responsibility (odds ratio = 9.0) and items related to fear of cross-infection or lack of knowledge of HIV. ...

Juvenile Nasopharyngeal Angiofibroma (JNA) is a rare, benign, locally invasive, vascular neoplasm... more Juvenile Nasopharyngeal Angiofibroma (JNA) is a rare, benign, locally invasive, vascular neoplasm that accounts for less than 0.5% of all head and neck tumors. Other terms used for this tumor are nasopharyngeal angiofibro ma, bleeding fib ro ma of adolescence, fibroangioma. In this paper, we present a rare case of Juvenile Nasopharyngeal Angiofibro ma in a 19 years old male patient.