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Papers by alia halim

International journal of health sciences

Aim: The goal of this study is the comparison of the mean reduction in serum bilirubin after inte... more Aim: The goal of this study is the comparison of the mean reduction in serum bilirubin after intermittent and continuous phototherapy for neonatal jaundice treatment. Study Design: A randomized controlled study. Place and Duration: In the Pediatric department of Mardan Medical Complex (MMC), Mardan for one-year duration from July 2021 to June 2022. Methodology: Total 200 children were registered after meeting the exclusion and inclusion criteria to compare the reduction in serum bilirubin following intermittent/ continuous phototherapy for neonatal jaundice treatment. There were 100 children in both Group A and B. The continuous phototherapy was given in Group A children while intermittent phototherapy was given in group B. The children in Group A were given continuous phototherapy (2 hrs with 20 mints break), and intermittent phototherapy was given in group B children (1 hr therapy and 30 Mints break).

Pakistan Journal of Medical and Health Sciences

Neonatal sepsis is the significant reason of neonatal mortality and morbidity and mostly results ... more Neonatal sepsis is the significant reason of neonatal mortality and morbidity and mostly results in extended hospitalization of infants in the neonatal intensive care unit. The sepsis was confirmed by a positive blood culture and a condition is considered clinical sepsis when the blood culture is negative. It is practically not possible to clinically differentiate sepsis from neonatal meningitis. However, a positive CSF for pathogenic bacteria indicates meningitis. Aim: The purpose of this study was to evaluate the frequency of late-onset sepsis in neonates with meningitis and to determine whether CSF analysis and lumbar puncture is mandatory in all cases of late-onset sepsis. Methods: This study was conducted in the Paediatrics department of CMH Abbottabad, and Sharif Medical City Hospital Lahore, and Pathology department of Women Medical and Dental College, Abbottabad for the duration from January 2022 to June 2022 among neonates with late neonatal sepsis. All neonates underwent c...

Rawal Medical Journal, 2017

Objective: To determine validity of pyuria in detecting urinary tract infection (UTI) as a quick ... more Objective: To determine validity of pyuria in detecting urinary tract infection (UTI) as a quick reliable, first hand diagnostic tool in our population, where cost effectiveness is involved and facilities of culture are not available. Methodology: This prospective cross-sectional study was conducted in KRL hospital, Islamabad, Pakistan over a period of 2 years. Urine samples of all the febrile children with suspected UTI were collected via midstream clean catch technique (in children >3 years) or suprapubic aspiration (in ≤3 years). They were examined microscopically after centrifugation for pus cells. Simultaneously cultures were performed. Specificity, sensitivity, negative and positive predictive values were calculated. Results: Total number of patients was 226. 45.58% were male and 54.42% were females. Mean age was 5.019±3.274 years. Mean weight was 19.575±8.339kg. Pyuria had sensitivity of 68.69%, specificity of 74.80%, PPV of 68% and NPV of 75.40% in detecting UTI. Conclusi...

Journal of Shifa Tameer-e-Millat University, 2021

Background: Malnutrition in under five children is prevalent in our country. It makes them prone... more Background: Malnutrition in under five children is prevalent in our country. It makes them prone to infections and increases child mortality. This can be controlled by identifying and modifying the predisposing factors. Objective: To assess nutritional status and to analyze the influence of various demographic factors on nutritional status of under five children. Methodology: This cross-sectional study was conducted in Shifa Falahi and Community Health center in Islamabad. Children under five years of age were included. Information was collected from mothers on a self-designed questionnaire. Weight and height of children was recorded and classified according to WHO Z score. Data was evaluated on SPSS 20. Univariate analysis was done to determine independent effect of each predictor on outcome. Results: Total of 280 patients were enrolled. 162 (57. 9%) of them were malnourished. Stunting was seen in 24.6% cases, while 26.1% were underweight. Wasting was seen in 19.6% cases. More mal...

Pakistan Armed Forces Medical Journal

Objective: To compare procalcitonin and C-reactive protein in the detection of neonatal sepsis ke... more Objective: To compare procalcitonin and C-reactive protein in the detection of neonatal sepsis keeping blood culture as gold standard. Study Design: Cross sectional study. Place and Duration of Study: Neonatal Intensive Care Unit, Children Hospital, Pakistan Institute of Medical Sciences, Islamabad, from Jul to Dec 2018. Methodology: Neonates up to 28 days of age with the suspicion of sepsis were selected. All the patients with congenital malformation were excluded. Two bed-sided tests i.e., procalcitonin and C-reactive protein was performed using standardized laboratory methods. The diagnostic strength of both tests was compared. Results: A total of 154 neonates were enrolled in this study. Male neonates were dominant in this study 95 (61.7%). The mean age of patients was 6.1 ± 3.8 days. C reactive protein had a sensitivity and specificity of 50.9% and 28.7% respectively. While procalcitonin was found to have a comparatively high sensitivity and specificity 73.6% and 38.6% respecti...

Journal of the College of Physicians and Surgeons Pakistan

Objective: To compare the need of mechanical ventilation between LISA (less invasive surfactant a... more Objective: To compare the need of mechanical ventilation between LISA (less invasive surfactant administration) method and conventional INSURE method (INtubation SURfactant administration and Extubation) in spontaneously breathing preterm infants with respiratory distress syndrome (RDS).

JPMA. The Journal of the Pakistan Medical Association, 2018

Bartter syndrome is an autosomal recessive disorder caused by gene mutations that involve hypokal... more Bartter syndrome is an autosomal recessive disorder caused by gene mutations that involve hypokalaemia, hypochloraemia and metabolic alkalosis along with raised serum renin, hyperaldosteronism and normal blood pressure. We report two cases of neonatal Bartter syndrome. Case 1 was a product of non-consanguineous marriage and mother had unexplained polyhydramnios in pregnancy while case 2 was a product of consanguineous marriage. Both cases were diagnosed based on hypokalaemia, hypochloraemia and metabolic alkalosis along with elevated serum renin and aldosterone levels. Case 1 positively responded to indomethacin while case 2 had Protein C and S deficiency and sepsis as coexisting diseases and thus could not be given indomethacin and expired. Regular antenatal visits can help in diagnosis of the syndrome particularly if unexplained poly hydramniosis investigated .

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018

McKusick-Kaufman Syndrome (MKKS) is one of rare syndromes which presents as polydactyly, hydromet... more McKusick-Kaufman Syndrome (MKKS) is one of rare syndromes which presents as polydactyly, hydrometrocolpos (HMC) and cardiac anomalies. This autosomal recessive disorder occurs due to mutations in MKKS gene. It is characterised predominantly by genitourinary and digit abnormalities. The diagnosis can be made on clinical findings; however, it is important to rule out Bardet-Biedl syndrome before making the definitive diagnosis. Treatment of MKKS revolves around treatment of its manifestations and complications. We hereby report a case of neonate with features of MKKS.