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Phytochemistry Reviews
Flavonoids are a class of phenolic natural products, well-identified in traditional and modern me... more Flavonoids are a class of phenolic natural products, well-identified in traditional and modern medicines in the treatment of several diseases including viral infection. Flavonoids showed potential inhibitory activity against coronaviruses including the current pandemic outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and designated as COVID-19. Here, we have collected all data related to the potential inhibitory mechanisms of flavonoids against SARS-CoV-2 infection and their significant immunomodulatory activities. The data were mapped and compared to elect major flavonoids with a promising role in the current pandemic. Further, we have linked the global existence of flavonoids in medicinal plants and their role in protection against COVID-19. Computational analysis predicted that flavonoids can exhibit potential inhibitory activity against SARS-CoV-2 by binding to essential viral targets required in virus entry and/ or replication. Flavonoids also showed excellent immunomodulatory and anti-inflammatory activities including the inhibition of various inflammatory cytokines. Further, flavonoids showed significant ability to reduce the exacerbation of COVID-19 in the case of obesity via promoting lipids metabolism. Moreover, flavonoids exhibit a high safety profile,
Ipomoea eriocarpa R.Br. belongs to family Convolvulaceae often called morning glories, are summer... more Ipomoea eriocarpa R.Br. belongs to family Convolvulaceae often called morning glories, are summer annual or perennial broadleaf plants. They are slender twining herb. It is occasionally consumed as an edible leafy vegetable or mixed with other food. An oil extract of Ipomoea eriocarpa is used for external application in headache, rheumatism, leprosy, ulcers and fevers. By reviewing the current literature, no botanical studies were done on Ipomoea eriocarpa R.Br., so this study aims to characterization and identification of this plant in both powdered and entire forms.
Phytochemistry Reviews
Flavonoids are a class of phenolic natural products, well-identified in traditional and modern me... more Flavonoids are a class of phenolic natural products, well-identified in traditional and modern medicines in the treatment of several diseases including viral infection. Flavonoids showed potential inhibitory activity against coronaviruses including the current pandemic outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and designated as COVID-19. Here, we have collected all data related to the potential inhibitory mechanisms of flavonoids against SARS-CoV-2 infection and their significant immunomodulatory activities. The data were mapped and compared to elect major flavonoids with a promising role in the current pandemic. Further, we have linked the global existence of flavonoids in medicinal plants and their role in protection against COVID-19. Computational analysis predicted that flavonoids can exhibit potential inhibitory activity against SARS-CoV-2 by binding to essential viral targets required in virus entry and/ or replication. Flavonoids also showed excellent immunomodulatory and anti-inflammatory activities including the inhibition of various inflammatory cytokines. Further, flavonoids showed significant ability to reduce the exacerbation of COVID-19 in the case of obesity via promoting lipids metabolism. Moreover, flavonoids exhibit a high safety profile,
Ipomoea eriocarpa R.Br. belongs to family Convolvulaceae often called morning glories, are summer... more Ipomoea eriocarpa R.Br. belongs to family Convolvulaceae often called morning glories, are summer annual or perennial broadleaf plants. They are slender twining herb. It is occasionally consumed as an edible leafy vegetable or mixed with other food. An oil extract of Ipomoea eriocarpa is used for external application in headache, rheumatism, leprosy, ulcers and fevers. By reviewing the current literature, no botanical studies were done on Ipomoea eriocarpa R.Br., so this study aims to characterization and identification of this plant in both powdered and entire forms.