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Papers by amir imani

Faṣlnāmah-i Pizhūhish/hā-yi Rāhburdī-i Siyāsat, 2017

One of the the most important issues in middle east and contemporary turkey is the study of stabi... more One of the the most important issues in middle east and contemporary turkey is the study of stability and threat factors of democracy. Among the other countries of middle east, turkey has long-term experience in democracy. A glance to the country show turkey s democracy has fluctuating matter. In the other words, democracy in turkey as a form of government and a kind of relations between society and the government have face threat and stability factors simultaneously. The main goal of the article is evaluating causes of the issue. the article argues some variables such as turkey s constitution amendments, party system and trying to accession to EU (stability variables) and ethnic threats, religious minorities challenges and the military interventions (threat stability) have influenced turkey s democracy. to evaluate the hypothesis, the article has some sections such as theoretical framework with emphasis on stability and threat factors, historical approach to democracy trends in tur...

International Journal of Psychology, 2020

Mindfulness-based stress reduction (MBSR) is an effective program for improving well-being. A gro... more Mindfulness-based stress reduction (MBSR) is an effective program for improving well-being. A growing body of studies is exploring the mechanisms mediating its beneficial effects. Integrative self-knowledge (ISK) is the construct of focus in this study. The primary goal of the current study was to investigate the mediating role of ISK in the relationship between improved mindful observing (MO), non-judging inner experience (NJ), and well-being following an MBSR program with an Iranian sample. Participants (n = 118) enrolled in MBSR and completed depression, anxiety, stress (DASS), Bartone Symptoms Checklist (BSC), Five-Facet Mindfulness Questionnaire, and ISK scale before and after the program. Results showed significant reductions in BSC, DASS, and improvements in MO, NJ, and ISK at the end of the program. Mediation analyses revealed that changes in ISK significantly mediated the relationship between changes in MO and NJ and symptoms (MO indirect effect on DASS: β = 0.11, confidence interval [CI] [0.003, 0.29]; NJ indirect effect on DASS: β = 0.12, CI [-0.16, 0.45]; MO indirect effect on BSC: β = 0.08, CI [0.001, 0.27]; NJ indirect effect on BSC: β = 0.09, CI [0.01, 0.22]). Improvements in MO and NJ may provide a pathway to cultivating ISK in MBSR, which may lead to enhanced well-being.

Atherosclerosis, 2020

BACKGROUND AND AIMS DNA damage and repair have been shown to be associated with carotid artery re... more BACKGROUND AND AIMS DNA damage and repair have been shown to be associated with carotid artery restenosis and atherosclerosis. The proliferation and migration of vascular smooth muscle cells (VSMCs) is the main cause of artery stenosis. This study aims to define the relationship between DNA damage and VSMCs proliferation. METHODS A rat carotid artery injury model was established, and human and rat VSMCs cultured in vitro. H2O2 was used to induce DNA damage in vitro. The selected CHK1 inhibitor, LY2603618, was used to inhibit CHK1 phosphorylation both in vivo and in vitro. γH2AX, αSMA and phosphorylated CHK1 were detected both in rat carotid artery and cultured VSMCs from different groups. Hyperplasia ratio of rat carotid artery intimal was measured. RESULTS DNA double-strand breaks occur in the rat carotid artery after injury. DNA damage induces CHK1 phosphorylation and down-regulates αSMA expression in VSMCs both in vitro and in vivo. The inhibition of CHK1 phosphorylation rescues ...

Crescent Journal of Medical and Biological Sciences, 2014

Objective: Fluoxetine is widely used in the treatment of neurological disorders. Hence, consideri... more Objective: Fluoxetine is widely used in the treatment of neurological disorders. Hence, considering the adverse effects of this drug on the endocrine axes of the body is very important. Fluoxetine has been shown to cause significant changes in testicular tissue structure and sex hormones in rats. It seems that antioxidant compounds such as vitamin E can reduce free radicals and inhibit these changes. Therefore, the aim of this study is to investigate the therapeutic effects of vitamin E on testicular tissue damage caused by fluoxetine use. Materials and Methods: In the present study, 40 Wistar rats (weight = 250 ± 10 gr) were randomly divided into 4 groups; control group that received normal saline (with intraperitoneal (IP) method), fluoxetine group (n = 10) that received 10 mg/kg of fluoxetine (IP), vitamin E group (n = 10 that received 100 mg/kg of vitamin E (IP), and the treatment group that received both vitamin E (100 mg/kg) and fluoxetine (10 mg/kg) for 28 days. On the 28 th ...

ArXiv, 2020

Online learning policy makes visual trackers more robust against different distortions through le... more Online learning policy makes visual trackers more robust against different distortions through learning domain-specific cues. However, the trackers adopting this policy fail to fully leverage the discriminative context of the background areas. Moreover, owing to the lack of sufficient data at each time step, the online learning approach can also make the trackers prone to over-fitting to the background regions. In this paper, we propose a domain adaptation approach to strengthen the contributions of the semantic background context. The domain adaptation approach is backboned with only an off-the-shelf deep model. The strength of the proposed approach comes from its discriminative ability to handle severe occlusion and background clutter challenges. We further introduce a cost-sensitive loss alleviating the dominance of non-semantic background candidates over the semantic candidates, thereby dealing with the data imbalance issue. Experimental results demonstrate that our tracker achi...

Phytotherapy Research, 2020

Because of the extensive biological functions of natural substances such as bioflavonoids, and th... more Because of the extensive biological functions of natural substances such as bioflavonoids, and their high safety and low costs, they could have high priority application in the health care system. The antioxidant properties of rutin, a polyphenolic bioflavonoid, have been well documented and demonstrated a wide range of pharmacological applications in cancer research. Since chemotherapeutic drugs have a wide range of side effects and rutin is a safe anticancer agent with minor side effects so recent investigations are performed for study of mechanisms of its anticancer effect. Both in‐vivo and in‐vitro examinations on anticancer mechanisms of this natural agent have been widely carried out. Regulation of different cellular signaling pathways such as Wnt/β‐catenin, p53‐independent pathway, PI3K/Akt, JAK/STAT, MAPK, p53, apoptosis as well as NF‐ĸB signaling pathways helps to mediate the anticancer impacts of this agent. This study tried to review the molecular mechanisms of rutin anticancer effect on various types of cancer. Deep exploration of these anticancer mechanisms can facilitate the development of this beneficial compound for its application in the treatment of different cancers.

Scientia Iranica, 2020

In recent years, the construction of high-rise buildings as an urban development strategy has bee... more In recent years, the construction of high-rise buildings as an urban development strategy has been accepted in many megacities. High-rise buildings have positive as well as negative impacts on urban environments. Therefore, the environmental impact assessment of high-rise buildings for establishing strategies to ensure sustainable and resilient urban development is essential. In this study, the environmental impact of high-rise buildings with a resilient development mindset was assessed. Resilience mindset provides an approach for including the uncertainties and interdependence of systems and processes for planning new sustainable developments and assessment methods. The corresponding environmental impact assessment was performed by monitoring the structural changes and their impacts on the function of ecosystem and environmental services. Here, the positive and negative impacts of high-rise buildings were evaluated. Protection of impervious surfaces as a positive impact and changing the natural pattern of urban wind ow as a negative impact were considered. The transparency of the results and the reduction of uncertainty are the advantages of using the resilience mindset in the environmental impact assessment. The results of this study suggest that the resilient development mindset can improve the environmental assessment through the adoption of appropriate indicators on multiple scales and di erentiating between the primary and secondary e ects.

International Journal of Clinical Cardiology, 2020

The novel coronavirus causes severe acute respiratory syndrome 2, and can infect any population. ... more The novel coronavirus causes severe acute respiratory syndrome 2, and can infect any population. With the currently available information on the behavior of the pandemic, we conclude that the virus has come to stay. It is clear that the most aggressive behavior and worst outcome of the infection occurs in already established risk groups, such as those with cardiovascular disease. Those with congenital heart disease make up a special risk group. Due to this group's high heterogeneity and the paucity of published cases related to coronavirus infection, its ultimate behavior cannot yet be known. Based on the anatomical and hemodynamic abnormalities with systemic repercussions which accompany congenital heart disease, this review was carried out with the aim of describing and analyzing this population's risk factors and potentially increased vulnerability to coronavirus infection. Systemic hematological abnormalities, along with the prothrombotic state, proinflammatory state, and altered immune response in cyanotic congenital heart disease are highlighted; along with the arrhythmias, pulmonary hypertension, underlying heart failure and target organ damage, among others, present in unrepaired congenital heart disease. This review searched for articles in PubMed, Science Direct, SciELO, MD Consult and Google Scholar using the MeSH terms "coronavirus disease 2019", "COVID-19", "SARS-CoV-2 pandemic", "coronavirus and cardiovascular system", "congenital heart diseases", "hematologic disorders in congenital heart disease", and "pro-inflammatory mediators". Finally, a brief description of the collateral effects of the pandemic on the care of this population is provided.

Transactions on Emerging Telecommunications Technologies, 2020

Silicon, 2018

The main purpose of this study is to calculate the Young's modulus of carbonic (c-graphene), sili... more The main purpose of this study is to calculate the Young's modulus of carbonic (c-graphene), silicon-carbide (SiC) and silicene graphene-like structures using density functional theory (DFT). Our results show that an increase in the number of layers did not noticeably change the Young's modulus of carbonic and silicon-carbide graphene, while the Young's modulus of silicene sheets decreased. Moreover, we found that carbonic graphene had the highest Young's modulus among the abovementioned graphene sheets due to having the shortest distance between its elements. In contrast, silicene graphenes had the lowest mechanical properties and highest equilibrium Si-Si distance. We also investigated the existing van der Waals interfacial interaction between the layers of the multilayer graphene structure using the Lennard-Jones potential. We used the Lennard-Jones parameters (ε and σ) to model the van der Waals interaction as a classical linear spring. Finally, the densities of states (DOS) were calculated to better understand the electronic properties of these systems.

International Journal of Women's Health and Reproduction Sciences, 2013

Annals of Neurology, 2011

Cellular therapy is an investigational approach for stroke. Mononuclear cells (MNCs) from the bon... more Cellular therapy is an investigational approach for stroke. Mononuclear cells (MNCs) from the bone marrow reduce neurological deficits in animal stroke models. We determined if autologous MNC infusion was feasible and safe in patients with ischemic stroke. We conducted an open-label prospective study of a bone marrow harvest followed by readministration of autologous MNCs in 10 patients, 18 to 80 years old, with acute middle cerebral artery ischemic stroke. Bone marrow was aspirated from the iliac crest, and MNCs were separated at a Good Manufacturing Practices facility and administered intravenously up to a maximum of 10 million cells/kg. The harvest and infusion had to occur between 24 and 72 hours after stroke. Patients were monitored for 6 months. Bone marrow aspiration was successfully completed in all patients. Eight received 10 million cells/kg, and 2 received ≥7 million cells/kg. There were no significant adverse events related to harvest or infusion. Two patients had infarct expansion between enrollment and harvest and underwent hemicraniectomy after cell infusion. One patient died at 40 days due to a pulmonary embolism related to the stroke. There were no study-related severe adverse events. Median National Institutes of Health Stroke Scale score was 13 before harvest, 8 at 7 days, and 3 at 6 months. At 6 months, all surviving patients had shifted down by at least 1 point on the modified Rankin Scale compared to day 7. Seven of 10 patients achieved a Barthel Index ≥90. This study suggests that a bone marrow harvest and reinfusion of autologous MNCs were safe and feasible in acute stroke patients.

International Journal of Electrical Power & Energy Systems, 2022

Artificial Intelligence Applications in Electrical Transmission and Distribution Systems Protection, 2021

2019 24th Electrical Power Distribution Conference (EPDC), 2019

In this paper, a comprehensive control strategy of hybrid power source is presented to provide re... more In this paper, a comprehensive control strategy of hybrid power source is presented to provide required electricity for a standalone DC power system in rural residential area. This hybrid system consists of Proton Exchange Membrane Fuel cell (PEMFC), a photovoltaic (PV) system and a supercapacitor (SC). The main aim of this paper is establishing a kind of hybrid power management for ensuring electricity production without interruption regarding to the PEMFC and PV uncertainties and limitations. The reason of utilizing the SC is covering the low dynamic of PEMFC against the fast load variation because of high power density of SC. Maximum Power Point Tracker (MPPT) controller is implemented for PV system by means of a new DC-DC converter topology. This proposed topology let us to control DC bus voltage at the same time. In addition, the Fuzzy logic controller is applied in different parts of the system such as PV MPPT and PEMFC voltage regulation. Ultimately, the simulation result are...

Case Description- A 25-year-old Arab mare, presented to the department of surgery of veterinary h... more Case Description- A 25-year-old Arab mare, presented to the department of surgery of veterinary hospital of Shahid Chamran university of Ahvaz with the signs of breathing disorder, snoring,and localizedinfections ofthe nosein the right nostril. Clinical Findings- Physical examination revealed a mass in the nasal vestibule which attached to the septum and caused partial obstruction ofthenasal canal. Treatment and Outcome- Surgical removal of the mass applied under general anesthesia. Well differentiated SCC was diagnosed based on the results of histopathological examination. Clinical Relevance- Squamous cell carcinoma (SCC), a malignant, locally invasive neoplasia of squamous epithelial cells, is the second most common tumor in horses.This report describes the SCC in the nasal septum of a horse, as a very rare location for neoplasm.