ayesha Mughal - Academia.edu (original) (raw)

Papers by ayesha Mughal

$Research paper thumbnail of Prevalence of inadequate vitamin D level and its predictors in children presenting with torus fractures$

European Journal of Orthopaedic Surgery & Traumatology

Journal of Pakistan Orthopaedic Association, 2020

International Journal of Clinical Practice, 2020

Objectives: Malnutrition is a crucial health problem predominantly in the developing countries. M... more Objectives: Malnutrition is a crucial health problem predominantly in the developing countries. Malnutrition in children is one of the main risk factors for diseases and mortality. Club foot or congenital talipes equinovarus (CTEV) is the most common form of congenital orthopedic abnormality. Over the past twenty years, the Ponseti method is considered the gold standard for the treatment of clubfoot. Our objective is to determine the prevalence of malnutrition in clubfoot patients, and its effects on the outcome of Ponseti technique in patients presenting to the Orthopedic Clinic of tertiary care Hospital in Karachi, Pakistan. Method: The cross-sectional study was conducted from Jan to Dec 2018.Total 153 clubfoot patients were treated and the World health organization classification of weight-forage index was used to assess the nutritional status of patients and its impact on outcome of Ponseti technique was recorded and analyzed with a P value ≤0.05 as significant. Results: Out of 153 patients, 112(79.7%) were found in good nutritional status and 42(20.6%) were malnourished. The average number of casts per patient and patients requiring 6+ casts in the undernutrition group was higher compared to good nutrition group (45.5% vs. 21.42% respectively). The number of Achilles tenotomy performed in the undernutrition group was also higher (76.4% vs. 51.8%). Conclusion: A significant correlation between patients nutritional status and outcome of the Ponseti technique is found as it influences the number of casts, possible relapse and failure of treatment.

Objective:To report the clinical characteristic of primary tibial synovial sarcoma, in terms of a... more Objective:To report the clinical characteristic of primary tibial synovial sarcoma, in terms of aggressiveness, local spread/ metastasis, surgical procedures and final outcome. Methods:3 case reports conducted and diagnosed in last 10 years were included and examine clinically as well radiologically. and ultimate surgical procedures performed and post operative follow up were studied and recorded. Patients diagnosed and procedures performed at other centre were excluded. All three patients underwent wide surgical excision and reconstruction with non vascularized fibular graft. Clinical and radio graphical follow up of 3 years done to see any recurrence and other complications. Results: three cases of primary tibial synovial sarcoma diagnosed in study period, all of them were female and in teen age, 2 were of 17 years and one 19 years old. One case of 19 years female present with history of 1 year of swelling and pain of leg.Second and third case of 17 years age present with history ...

Results: The total measured blood loss in tranexamic acid group (276 ± 53 mL) when comparing to c... more Results: The total measured blood loss in tranexamic acid group (276 ± 53 mL) when comparing to control group (523 ± 74 mL) was less significantly. The requirement of blood transfusion in comparison was high in the control group and post traumatic hematocrit values were higher with in the tranexamic acid group.After administration of tranexamic acid in traumatic patients there have been no clinically relevant differences within the vital signs and no thromboembolic complications were detected in either group.Conclusion: In traumatic patients, the prophylactic usage of tranexamic acid has effectively decreased blood loss, transfusion needs and hospital stay without any complication or adverse effects of thrombosis. Thus, TXA can be used safely and effectively in trauma subjects. Method: Prospectively conducted randomized doubleblind placebo controlled study carried out. Patients were blindly randomized into two groups to receive either intravenous 1gm tranexamic acid 20 min or similar volume of 0.9% saline as placebo (P).Inclusion criteria was based on pulse rate >110 per min or systolic pressure level <90mmHg, hemorrhage or in danger of serious hemorrhage. Patients' total blood loss was measured, needs of transfusion and hospital stay recorded. The post traumatic hemoglobin, hematocrit values, serum creatinine, activated thromboplastin time, prothombin time, platelets count and pulmonary embolism symptoms were comparatively evaluated. Background: In traumatic patients there is increase loss of blood and requires excessive blood transfusion as compared to other diseases. Clinical efficacy and clinical safety of tranexamic acid in decreasing blood loss assess during this study in post traumatic patients.

International Journal of Research in Orthopaedics, 2020

Background: To determine the prevalence and association of hyperuricemia with genetic factors, di... more Background: To determine the prevalence and association of hyperuricemia with genetic factors, dietary and alcohol consumption, metabolic syndrome, diuretic use and chronic renal disease in patients presenting with joint pain in the outpatient department (OPD) at a tertiary care hospital of Karachi, Pakistan and to establish a significant correlation between concentration of serum creatinine and triglyceride with uric acid concentration statistically.Methods: This study was conducted on 2200 patients. The data included age, gender, occupation, genetic factors (family history), dietary and alcohol consumption, metabolic syndrome, hypertension, obesity, diuretic use and chronic renal disease. Serum uric acid concentration of 2.4-6.0 mg/dl (female) and 3.4-7.0 mg/dl (male) labelled as normal values. All participants’ serum uric acid concentration compared with serum creatinine and triglyceride concentration.Results: Overall prevalence of 30.1% (662 patients) hyperuricemia in patients p...

Abstracts, 2018

Background: The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introd... more Background: The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introduced in Karachi to meet the transportation demand of the growing population. These vehicles have directly or indirectly been implicated in a number of road traffic violations as well as road accidents. This study aims to describe the crash characteristics and injury patterns for Qing-qi rickshaw occupants and other road users hit by Qing-qi rickshaw in Karachi, Pakistan. Methods: An Observational/ Descriptive study was conducted at Accident& Emergency and Orthopaedic Surgery Department, Jinnah Post Graduate Medical Centre, Karachi Pakistan from July 2014 to June 2015.All patients who came with Qing-qi rickshaw accident in Accident& Emergency (A&E) of JPMC were included. Crash characteristics, details of injuries, injury severity parameters and outcome were documented in detailed interviews. Results: Four hundred and eighty-six rickshaw related injuries were noted in road traffic accidents by Qing-gi rickshaw. Age range was 2-85 (43.5±58.68). 350 injured victims were males and 136 were females. By occupation most victims were laborers and daily wage workers (45%) and students (21%). Overloading of vehicle with more than two passengers was found in (28.5%). The most common cause of injury was collision with a moving vehicle (56%), followed by fall from rickshaw. The most common contributing factor was the overloading of rickshaw and roll over on turning (61%). Injury severity on arrival were mild (49%), moderate were (32%), and severe were (19%). Injuries related to head and neck (26%), face (14%), thorax and abdomen (5%), lower extremity and pelvic girdle (31%) and upper extremity (23%) were observed. Conclusion: Qing-qi rickshaw injuries are common and these vehicles are vulnerable to road traffic accidents. Occupants and road users are both at risk of injuries.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018

Hydatid disease is helminthic infection caused by tape worm echinococcus granulosis. It commonly ... more Hydatid disease is helminthic infection caused by tape worm echinococcus granulosis. It commonly involves liver (65-75%) and the lungs (25 to 30%). Involvement of bones and skeletal muscle is very rare, i.e. 3 to 5%. This is the report of a 21-year girl, city resident, presented with mass involving left proximal thigh. The mass was painless and had gradually increased in size over three years. MRI revealed solid cum cystic lesion in vastus medialis muscle. Tru-Cut needle biopsy of the lesion revealed necrotic material. Intraoperative findings were of different sized cystic lesions, typical of hydatid cyst. The cysts were removed intact. No recurrence was seen in 11-month follow-up. Hydatid cyst involving skeletal muscle is very rare entity, but should be considered while making differential diagnosis of soft tissue mass.

$Research paper thumbnail of Level of osteoporosis awareness and its related factors in low density distal radius fractures patients aged 50 years and older in Asian country$

Osteoporosis and Sarcopenia, 2017

Introduction: Osteoporosis is an important health problem not only in terms of morbidity mortalit... more Introduction: Osteoporosis is an important health problem not only in terms of morbidity mortality and negative effects on quality of life but health related cost as well. Because of rapid increase in ageing population in Asia, osteoporosis has become one of the most prevalent and costly health problems. Distal radius fracture which is considered as one of the most frequent fractures seen is now shown to be associated with an increased risk of further fractures. Not much is known about the level of awareness of the condition among these patients of distal radius fracture in Asian country. Awareness and treatment of osteoporosis is significant to prevent further fractures in patients with osteoporosis. The aim of this study was to evaluate the awareness of osteoporosis and related factors in distal radius fracture patients. Materials & methods: Cross sectional study was conducted on low energy distal radius fracture patients aged 50 years and over who presented in Emergency Department of tertiary care hospital Karachi Pakistan from Jan 2016 to Dec 2016. Thequestionnaire designed had three sections: demographic information, knowledge about osteoporosis andthe risk factors for osteoporosis which was applied to all patients after receiving consent.Data was analyzed on SPSS 21 for statistical significance. Results: Total number of patient with distal radius fracture were 480, 352(73.33%) female and 128(26.66%) male.The average age was 72.5 years, with a minimum of 50 and a maximum of 95 SD± 31.81. Only 98(20.41%) had awareness about osteoporosis, and 382(79.58%) did not know what it was. Considering the educational levels 210(43.75%) of patients were not able to read and write or ever went to school, 52.5%, 158(32.91%) didnot get primary education and 112(23.33%) were secondary or high school graduates. Awareness of osteoporosis was directly related to the level of education. With regard to sources of information, 312(65%) of patients reported physicians/doctors as the main source of information, followed by TV (15%), newspaper (10%). Other sources of information included: books (2%), family members (3%), friends (2%), radio (1%), pharmacists (1%) and Internet (1%). Lifestyle practices varied considerably. Nearly 15% reported smoking (observed mainly in male patients), 20% indicated they exercised for at least 30 minutes daily, and 1%reported drinking alcoholic beverages occasionally. 382(79.58%) patients did not know what were the risk factors leading to the development of osteoporosis. More than three quarters of patients could not identify risk factors such as vitamin D deficiency, family history of osteoporosis, poor eating habits, smoking, alcohol consumption, increasing age, some medications and menopause.

Journal of Ayub Medical College, Abbottabad : JAMC

The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introduced in Kara... more The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introduced in Karachi to meet the transportation demand of the growing population. These vehicles have directly or indirectly been implicated in a number of road traffic violations as well as road accidents. This study aims to describe the crash characteristics and injury patterns for Qing-qi rickshaw occupants and other road users hit by Qing-qi rickshaw in Karachi, Pakistan. An Observational/ Descriptive study was conducted at Accident & Emergency and Orthopaedic Surgery Department, Jinnah Post Graduate Medical Centre, Karachi Pakistan from July 2014 to June 2015.All patients who came with Qing-qi rickshaw accident in Accident & Emergency (A&E) of JPMC were included. Crash characteristics, details of injuries, injury severity parameters and outcome were documented in detailed interviews. Four hundred and eighty-six rickshaw related injuries were noted in road traffic accidents by Qing-gi rickshaw. Age r...

JPMA. The Journal of the Pakistan Medical Association, Nov 1, 2016

To assess the frequency, type of injuries and reason behind avoidable injuries due to dupatta ent... more To assess the frequency, type of injuries and reason behind avoidable injuries due to dupatta entrapment in motorcycle wheels among female pillion riders. This observational / descriptive study was conducted at the Jinnah Postgraduate Medical Centre, Karachi, from July 2013 to December 2014, and comprised female patients with dupatta-related motorbike injuries. The patients had injuries around head and neck, face, chest, abdomen, etc. SPSS 11 was used for data analysis. Of the 450 dupatta-related injuries, 49(10.89%) patients were admitted, whereas the remainder with minor injuries on neck and other parts of body were primarily managed in the accident and emergency department, detained for observation and discharged after first aid. The mean age was 31.5±19.09 years (range: 18 to 45 years). Besides, 37(75.51%) patients were admitted to the orthopaedic department, 5(10.2%) to the ear, nose and throat department, 4(8.16%) to the neurosurgery department and 2(4.08%) to the general surg...