ayush pal Bansal - Academia.edu (original) (raw)
Papers by ayush pal Bansal
Biomedical and Pharmacology Journal, 2020
Caesarean section is most commonly performed under spinal anaesthesia these days. One of the most... more Caesarean section is most commonly performed under spinal anaesthesia these days. One of the most common complication of spinal anaesthesia is post spina shivering occurring at the rate of as high as 85% in caesarian section. The present study aims at studying the effect of intrathecal tramadol in prevention of post spinal shivering. Methods: Sixty patients of American Society of Anaesthesiologist Class I and II were randomly divided into two groups and were given either normal saline (Group C) as control group or Tramadol (group T) as study group intrathecally as adjuvant along with Bupivacaine (hyperbaric) for spinal anaesthesia. The patients were monitored for intensity and incidence of shivering. Result: Statistically significant difference was found in the incidence as well as intensity of shivering among the two groups. The tramadol requirement was significantly reduced in the study group and there was no significant difference between the adverse effects seen in both the groups. Conclusion: We found that when tramadol was given intrathecally along with hyperbaric bupivacaine it was found to be effective in countering the side effect of shivering in parturient after spinal anaesthesia. Also, there was no significant difference in side effects like nausea, vomiting and pruritis due to use of tramadol in both the groups.
Journal of Evolution of Medical and Dental Sciences, Jul 20, 2020
BACKGROUND Saddle block is the most commonly used anaesthetic technique for perianal surgeries in... more BACKGROUND Saddle block is the most commonly used anaesthetic technique for perianal surgeries in adults. Perianal surgeries under saddle block are considered as day care surgeries. Major disadvantage is that the low volume of spinally given drug won't prolong duration of postoperative analgesia. Inj. Dexmedetomidine (α2-Adrenoceptor agonist) and Inj. Nalbuphine (opioid agonist-antagonist) were studied as an adjuvant as to whether they increase the duration of post-operative analgesia. Secondary objectives of this study were to compare hemodynamic stability and side effects among Inj. Dexmedetomidine and Inj. Nalbuphine. METHODS A total of 60 patients with American Society of Anaesthesiologist physical Status I and II scheduled for elective perianal surgeries were randomly allocated into two equal groups in this randomized prospective comparative study. Group D received 0.5% hyperbaric bupivacaine 0.8 mL + 5 mcg dexmedetomidine and group N received 0.5% hyperbaric bupivacaine 0.8 mL + 0.6 mg nalbuphine. Onset and duration of sensory and motor blockade, and duration of analgesia were recorded. Post-operative analgesic consumption and side effects were studied for 24 hours. Statistical analysis was done by using descriptive and inferential statistics using Chi-square test and Student's t-test. RESULTS Demographic characteristics, duration of surgery, onset of sensory and motor block were comparable. Duration of analgesia was 320.26 ± 89.52 min for dexmedetomidine (D) whereas it was 222.23 ± 25.43 min for nalbuphine (N) with a P value of <0.05. No side effects were noted. CONCLUSION A dose of 5 mcg dexmedetomidine as an adjuvant seems to be optimal for providing postoperative analgesia with better hemodynamic stability.
Generating paraphrases, that is, different variations of a sentence conveying the same meaning, i... more Generating paraphrases, that is, different variations of a sentence conveying the same meaning, is an important yet challenging task in NLP. Automatically generating paraphrases has its utility in many NLP tasks like question answering, information retrieval, conversational systems to name a few. In this paper, we introduce iterative refinement of generated paraphrases within VAE based generation framework. Current sequence generation models lack the capability to (1) make improvements once the sentence is generated; (2) rectify errors made while decoding. We propose a technique to iteratively refine the output using multiple decoders, each one attending on the output sentence generated by the previous decoder. We improve current state of the art results significantly - with over 9% and 28% absolute increase in METEOR scores on Quora question pairs and MSCOCO datasets respectively. We also show qualitatively through examples that our re-decoding approach generates better paraphrases...
Biomedical and Pharmacology Journal, 2020
Caesarean section is most commonly performed under spinal anaesthesia these days. One of the most... more Caesarean section is most commonly performed under spinal anaesthesia these days. One of the most common complication of spinal anaesthesia is post spina shivering occurring at the rate of as high as 85% in caesarian section. The present study aims at studying the effect of intrathecal tramadol in prevention of post spinal shivering. Methods: Sixty patients of American Society of Anaesthesiologist Class I and II were randomly divided into two groups and were given either normal saline (Group C) as control group or Tramadol (group T) as study group intrathecally as adjuvant along with Bupivacaine (hyperbaric) for spinal anaesthesia. The patients were monitored for intensity and incidence of shivering. Result: Statistically significant difference was found in the incidence as well as intensity of shivering among the two groups. The tramadol requirement was significantly reduced in the study group and there was no significant difference between the adverse effects seen in both the groups. Conclusion: We found that when tramadol was given intrathecally along with hyperbaric bupivacaine it was found to be effective in countering the side effect of shivering in parturient after spinal anaesthesia. Also, there was no significant difference in side effects like nausea, vomiting and pruritis due to use of tramadol in both the groups.
Journal of Evolution of Medical and Dental Sciences, Jul 20, 2020
BACKGROUND Saddle block is the most commonly used anaesthetic technique for perianal surgeries in... more BACKGROUND Saddle block is the most commonly used anaesthetic technique for perianal surgeries in adults. Perianal surgeries under saddle block are considered as day care surgeries. Major disadvantage is that the low volume of spinally given drug won't prolong duration of postoperative analgesia. Inj. Dexmedetomidine (α2-Adrenoceptor agonist) and Inj. Nalbuphine (opioid agonist-antagonist) were studied as an adjuvant as to whether they increase the duration of post-operative analgesia. Secondary objectives of this study were to compare hemodynamic stability and side effects among Inj. Dexmedetomidine and Inj. Nalbuphine. METHODS A total of 60 patients with American Society of Anaesthesiologist physical Status I and II scheduled for elective perianal surgeries were randomly allocated into two equal groups in this randomized prospective comparative study. Group D received 0.5% hyperbaric bupivacaine 0.8 mL + 5 mcg dexmedetomidine and group N received 0.5% hyperbaric bupivacaine 0.8 mL + 0.6 mg nalbuphine. Onset and duration of sensory and motor blockade, and duration of analgesia were recorded. Post-operative analgesic consumption and side effects were studied for 24 hours. Statistical analysis was done by using descriptive and inferential statistics using Chi-square test and Student's t-test. RESULTS Demographic characteristics, duration of surgery, onset of sensory and motor block were comparable. Duration of analgesia was 320.26 ± 89.52 min for dexmedetomidine (D) whereas it was 222.23 ± 25.43 min for nalbuphine (N) with a P value of <0.05. No side effects were noted. CONCLUSION A dose of 5 mcg dexmedetomidine as an adjuvant seems to be optimal for providing postoperative analgesia with better hemodynamic stability.
Generating paraphrases, that is, different variations of a sentence conveying the same meaning, i... more Generating paraphrases, that is, different variations of a sentence conveying the same meaning, is an important yet challenging task in NLP. Automatically generating paraphrases has its utility in many NLP tasks like question answering, information retrieval, conversational systems to name a few. In this paper, we introduce iterative refinement of generated paraphrases within VAE based generation framework. Current sequence generation models lack the capability to (1) make improvements once the sentence is generated; (2) rectify errors made while decoding. We propose a technique to iteratively refine the output using multiple decoders, each one attending on the output sentence generated by the previous decoder. We improve current state of the art results significantly - with over 9% and 28% absolute increase in METEOR scores on Quora question pairs and MSCOCO datasets respectively. We also show qualitatively through examples that our re-decoding approach generates better paraphrases...