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Papers by az wey

We summarize our work on devising protective barrier coats for use against airborne contamination... more We summarize our work on devising protective barrier coats for use against airborne contamination when using tert-butoxycarbonylmethyl (BOCME) capped fluoroalcohol resist resins as part of our strategy to develop a 157 nm resist platform. We will describe how a barrier coat (AZ EXP FX Coating 145) consisting of a fluoro-cyclopolymer formulation, soluble in aqueous developer, can improve the post-exposure delay (PED) latitude of 157 nm resist resists exposed under conditions or airborne contamination. Specifically, a 20 nm thick coating of AZ EXP FX Coating 145 gives a PED latitude for L/S features of at least 10 min under condition of airborne amine contamination (10 ppb amine contamination). The barrier coat, AZ EXP FX coating 145 is formulated in a solvent which is compatible with resist film coated from typical 193 nm resist spin casting solvents. Moreover, it can be easily removed as part of the normal aqueous base development scheme, no extra post-apply bake or stripping step is required.

In this study, we compared the texture features of mammographic parenchymal patterns (MPPs) of no... more In this study, we compared the texture features of mammographic parenchymal patterns (MPPs) of normal subjects and breast cancer patients and evaluated whether a texture classifier can differentiate their MPPs. The breast image was first segmented from the surrounding image background by boundary detection. Regions of interest (ROIs) were extracted from the segmented breast area in the retroareolar region on the cranio-caudal (CC) view mammograms. A mass set (MS) of ROIs was extracted from the mammograms with cancer, but ROIs overlapping with the mass were excluded. A contralateral set (CS) of ROIs was extracted from the contralateral mammograms. A normal set (NS) of ROIs was extracted from one CC view mammogram of the normal subjects. Each data set was randomly separated into two independent subsets for 2-fold cross-validation training and testing. Texture features from run-length statistics (RLS) and newly developed region-size statistics (RSS) were extracted to characterize the MPP of the breast. Linear discriminant analysis (LDA) was performed to compare the MPP difference in each of the three pairs: MS-vs-NS, CS-vs-NS, and MS-vs-CS. The Az values for the three pairs were 0.79, 0.73, and 0.56, respectively. These results indicate that the MPPs of the contralateral breast of breast cancer patients exhibit textures comparable to that of the affected breast and that the MPPs of cancer patients are different from those of normal subjects.

Journal of Experimental & Clinical Cancer Research, 2009

Background Epstein-Barr virus (EBV) has been shown to be associated with gastric cancer. However,... more Background Epstein-Barr virus (EBV) has been shown to be associated with gastric cancer. However, inconsistent findings have been reported regarding the distribution of EBV infected cells (in normal gastric epithelium vs. intestinal metaplastic cells vs. in neoplastic cells) and the characteristics of EBV-associated gastric cancer. Lymph node positive EBV-associated gastric cancer has not been systematically studied. The aims of this study were to evaluate EBV-associated gastric cancer, to assess the distribution of EBV infected cells including all positive lymph nodes, and to define the characteristics of EBV-associated gastric cancer. Design The study included primary gastric cancer patients who underwent surgical resection with no preoperative treatment at M.D. Anderson Cancer Center between 1987 and 2006. Formalin-fixed paraffin-embedded tissue from these resection specimens were assessed for EBV by in situ hybridization, the gold standard for EBV detection in tissue. EBV status was analyzed along with clinicopathologic parameters including age, gender, tumor type, lymph node status, and pathologic stage of the tumor. Results Among 235 patients, 12 had intranuclear expression of EBV. EBV staining was seen only in tumor cells and no detectable EBV was observed in normal gastric mucosa, intestinal metaplasia or stromal cells. Eight of 12 patients with EBV-associated gastric cancer had regional lymph node metastasis. Of note, metastatic tumor cells in all of the involved lymph nodes of these 8 cases contained EBV. The epidemiologic data showed 11 of the 12 patients with EBV-associated gastric cancer were men, ranging in age from 54 to 78 years (mean age, 60 years; median age, 62.1 years). The age distribution for non-EBV associated gastric cancer patients ranged from 21 to 93 years (mean age, 67 years; median age, 66.4 years). Conclusion Our study demonstrated that EBV is present exclusively in gastric cancer cells. The detection of EBV in tumor cells in all of the lymph nodes involved with metastatic gastric carcinoma suggests simultaneous replication of EBV and tumor cells. The predominantly male gender and relatively younger age observed for the EBV-infected gastric cancer cases suggest an association between this disease and other factors, such as life style.

We are developing new techniques to improve the performance of our computer-aided detection (CAD)... more We are developing new techniques to improve the performance of our computer-aided detection (CAD) system for clustered microcalcifications on full-field digital mammograms (FFDMs). In this study, we designed an information fusion scheme by using joint two-view information on craniocaudal (CC) and mediolateral-oblique (MLO) views. After cluster candidates were detected using a single-view detection technique, candidates on CC and MLO views were paired using their geometrical information. Candidate pairs were classified as true and false pairs with a similarity classifier that used the joint information from both views. Each cluster candidate was also characterized by its single-view features. The outputs of the similarity classifier and the single-view classifier were fused and the cluster candidate was classified as a true microcalcification cluster or a false-positive (FP) using the fused two-view information. A data set of 192 FFDM images was collected from 96 patients at the University of Michigan. All patients had two mammographic views. This data set contained 96 microcalcification clusters, of which 28 clusters were proven by biopsy to be malignant and 68 were proven to be benign. For training and testing the classifiers, the data set was partitioned into two independent subsets with the malignant cases equally distributed to the two subsets. One subset was used for training and the other subset was used for testing. We compared three computerized methods for geometrically pairing cluster candidates on two mammographic views. The areas under the fitted ROC curves were 0.75+/-0.01, 0.74+/-0.01, and 0.76+/-0.01 for the three methods, respectively. The difference between any two methods measured by the area under the fitted ROC curve, Az, was not statistically significant (p > 0.05). We also evaluated a new hybrid pairing scheme that used two different sensitivity levels for defining cluster pairs based on the single-view scores. The single-view CAD system achieved cluster-based sensitivities of 75%, 80%, and 85% at 0.48, 0.86, and 1.05 FPs/image, respectively. The joint two-view CAD system achieved the same sensitivity levels at 0.29, 0.46, and 0.89 FPs/image. When the hybrid pairing was used in the joint two-view CAD system, the same cluster-based sensitivities were achieved at 0.26, 0.37, and 0.88 FPs/image. Our results indicate that correspondence of cluster candidates on two different views provides valuable additional information for distinguishing FPs from true microcalcification clusters.

1.0 Nama Pengkaji : Zamzulaila binti Abdul Mutalib 2.0 Tajuk Penyelidikan : Bentuk Mata Keris Jaw... more 1.0 Nama Pengkaji : Zamzulaila binti Abdul Mutalib 2.0 Tajuk Penyelidikan : Bentuk Mata Keris Jawa di Johor 3.0 Pengenalan : Pada zaman dahulu kala mengikut daripada sumber yang diperolehi keris jawa ini terwujud dalam kerajaan majapahit kerana keris ini banyak dibuat dan digunakan oleh panglima-panglima dan masyarakat majapahit. keris jawa di buat di Jawa iaitu di Jawa Timur dan Jawa selatan. Keris jawa merupakan keris utama masyakat jawa pada zaman itu dan keris jawa melambangkan keberaniaan seseorang individu tersebut dan lambang kepada kejantanan seseorang lelaki tersebut. Tarikh Wujudnya keris tersebut tidak dapat saya pastikan tetapi melalui sumber yang saya perolehi keris jawa wujud semenjak tertubuhnya empayar Majapahit iaitu 1293 masihi. Pada zaman itu dikatakan keris jawa telah ada dalam masyarakat jawa dan menjadi adat sebahgian hiduo masyarakat Jawa. Kepercayaan masyarakat Jawa kepada keris jawa dari segi mistik, lagenda, teknik, dan hingga ke tata pembuatan juga menjadikan masyarat jawa pada masa itu menjadikan keris jawa sebahagian daripada peraturan dalam hidup mereka Keris merupakan salah satu senjata warisan masyarakat Nusantara. Keris sering digunakan dalam masyarakat dinusantara dalam kehidupan seperti keperluan..Hasil kajian masa kini yang dilakukan mendapati senjata yang berupa Keris hanya ada terdapat diNusantara dan tidak didapati dikawasan lain dalam dunia ini. Keris dicipta bukan sekadar untuk peperangan dan mempertahankan diri,ia juga merupakan pelbagai

Ultrasound in Medicine and Biology, 2009

Journal of Experimental & Clinical Cancer Research, 2009

Ultrasound in Medicine and Biology, 2009