bharat bhushan - Academia.edu (original) (raw)

Papers by bharat bhushan

Research paper thumbnail of Nanotribological characterization of perfluoroalkylphosphonate self-assembled monolayers deposited on aluminum-coated silicon substrates

Microsystem Technologies, 2006

Abstract Aluminum-coated silicon substrates are commonly used for various micro/nanooptoelectrome... more Abstract Aluminum-coated silicon substrates are commonly used for various micro/nanooptoelectromechanical systems (MOEMS/NOEMS) including Digital Micromirror Devices (DMD®). For efficient and failure proof operation of these devices, ultra-thin ...

Research paper thumbnail of Nanomechanical characterization of polymer beam structures for BioMEMS applications

Sensors and Actuators A: …, 2007

Polymer microstructures are incorporated in biomicroelectromechanical system (BioMEMS) devices wi... more Polymer microstructures are incorporated in biomicroelectromechanical system (BioMEMS) devices with applications ranging from drug screening to defense applications. Nanomechanical characterization of the polymer components must be carried out in order to design reliable devices. This paper presents the nanoindentation characterization of polymer beams fabricated through soft lithography-based techniques for BioMEMS applications. Poly(propyl methacrylate) (PPMA), poly(methyl methacrylate) (PMMA), polystyrene (PS) and a nanocomposite of polystyrene and clay (PS/Clay) were investigated in this study. The hardness, elastic modulus and creep behavior of microbeams made from these materials were measured using continuous stiffness measurement (CSM) nanoindentation, and the scratch resistance of thin films was measured using a nanoscratch technique. Yield and breaking strengths were determined by normal beam bending at elevated loads, in which the presence of the nanoclay filler in the composite modified the deformation behavior relative to the unfilled polystyrene. Lateral bending of PS and PS/Clay cantilever beams is demonstrated for the first time. The mechanical response of beams after soaking in deionized water or heating to human body temperature was examined.

Research paper thumbnail of Emerging applications of nanoparticles for lung cancer diagnosis and therapy

International Nano Letters, 2013

Lung cancer is by far the leading cause of cancer-related mortality worldwide, most of them being... more Lung cancer is by far the leading cause of cancer-related mortality worldwide, most of them being active tobacco smokers. Non small cell lung cancer accounts for around 85% to 90% of deaths, whereas the rest is contributed by small cell lung cancer. The extreme lethality of lung cancer arises due to lack of suitable diagnostic procedures for early detection of lung cancer and ineffective conventional therapeutic strategies. In course with desperate attempts to address these issues independently, a multifunctional nanotherapeutic or diagnostic system is being sought as a favorable solution. The manifestation of physiochemical properties of such nanoscale systems is tuned favorably to come up with a versatile cancer cell targeted diagnostic and therapeutic system. Apart from this, the aspect of being at nanoscale by itself confers the system with an advantage of passive accumulation at the site of tumor. This review provides a broad perspective of three major subclasses of such nanosc...

Research paper thumbnail of Genetic variability, heritability and genetic advance relating to physico-chemical properties of apricot (Prunus armeniaca L.) genotypes in Kashmir valley

HARYANA …, 2006

An experiment on evaluation in 36 genotypes of french bean was conducted at department of vegetab... more An experiment on evaluation in 36 genotypes of french bean was conducted at department of vegetable science, college of Horticulture, Bagalkot during rabi season of the year 2015-2016. The analysis of variance was significant (p=0.01) for all characters indicated higher magnitude of variability. Moderate GCV and PCV were observed for the traits plant height, number of primary branches, pod length, pod width, pod flesh thickness, number of pods / cluster, number of pods/ plant, weight of ten pods, number of root nodules/ plant, drymatter content of pods and roots. High heritability coupled with high genetic advance was recorded for the plant height, pod width, number of pods/plant, weight of ten pods, yield /plant, number of root nodules /plant, drymatter content of pods, roots and protein content. It indicated the presence of additive gene effects. Thus, there is an ample scope for improving yield and quality characters in french bean through direct selection.

Research paper thumbnail of Nanotribological characterization of perfluoroalkylphosphonate self-assembled monolayers deposited on aluminum-coated silicon substrates

Microsystem Technologies, 2006

Abstract Aluminum-coated silicon substrates are commonly used for various micro/nanooptoelectrome... more Abstract Aluminum-coated silicon substrates are commonly used for various micro/nanooptoelectromechanical systems (MOEMS/NOEMS) including Digital Micromirror Devices (DMD®). For efficient and failure proof operation of these devices, ultra-thin ...

Research paper thumbnail of Nanomechanical characterization of polymer beam structures for BioMEMS applications

Sensors and Actuators A: …, 2007

Polymer microstructures are incorporated in biomicroelectromechanical system (BioMEMS) devices wi... more Polymer microstructures are incorporated in biomicroelectromechanical system (BioMEMS) devices with applications ranging from drug screening to defense applications. Nanomechanical characterization of the polymer components must be carried out in order to design reliable devices. This paper presents the nanoindentation characterization of polymer beams fabricated through soft lithography-based techniques for BioMEMS applications. Poly(propyl methacrylate) (PPMA), poly(methyl methacrylate) (PMMA), polystyrene (PS) and a nanocomposite of polystyrene and clay (PS/Clay) were investigated in this study. The hardness, elastic modulus and creep behavior of microbeams made from these materials were measured using continuous stiffness measurement (CSM) nanoindentation, and the scratch resistance of thin films was measured using a nanoscratch technique. Yield and breaking strengths were determined by normal beam bending at elevated loads, in which the presence of the nanoclay filler in the composite modified the deformation behavior relative to the unfilled polystyrene. Lateral bending of PS and PS/Clay cantilever beams is demonstrated for the first time. The mechanical response of beams after soaking in deionized water or heating to human body temperature was examined.

Research paper thumbnail of Emerging applications of nanoparticles for lung cancer diagnosis and therapy

International Nano Letters, 2013

Lung cancer is by far the leading cause of cancer-related mortality worldwide, most of them being... more Lung cancer is by far the leading cause of cancer-related mortality worldwide, most of them being active tobacco smokers. Non small cell lung cancer accounts for around 85% to 90% of deaths, whereas the rest is contributed by small cell lung cancer. The extreme lethality of lung cancer arises due to lack of suitable diagnostic procedures for early detection of lung cancer and ineffective conventional therapeutic strategies. In course with desperate attempts to address these issues independently, a multifunctional nanotherapeutic or diagnostic system is being sought as a favorable solution. The manifestation of physiochemical properties of such nanoscale systems is tuned favorably to come up with a versatile cancer cell targeted diagnostic and therapeutic system. Apart from this, the aspect of being at nanoscale by itself confers the system with an advantage of passive accumulation at the site of tumor. This review provides a broad perspective of three major subclasses of such nanosc...

Research paper thumbnail of Genetic variability, heritability and genetic advance relating to physico-chemical properties of apricot (Prunus armeniaca L.) genotypes in Kashmir valley

HARYANA …, 2006

An experiment on evaluation in 36 genotypes of french bean was conducted at department of vegetab... more An experiment on evaluation in 36 genotypes of french bean was conducted at department of vegetable science, college of Horticulture, Bagalkot during rabi season of the year 2015-2016. The analysis of variance was significant (p=0.01) for all characters indicated higher magnitude of variability. Moderate GCV and PCV were observed for the traits plant height, number of primary branches, pod length, pod width, pod flesh thickness, number of pods / cluster, number of pods/ plant, weight of ten pods, number of root nodules/ plant, drymatter content of pods and roots. High heritability coupled with high genetic advance was recorded for the plant height, pod width, number of pods/plant, weight of ten pods, yield /plant, number of root nodules /plant, drymatter content of pods, roots and protein content. It indicated the presence of additive gene effects. Thus, there is an ample scope for improving yield and quality characters in french bean through direct selection.