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Papers by sonal bhatnagar

World Journal of Microbiology and Biotechnology

CRC Press eBooks, Nov 21, 2022

Current Nutrition Food Science, Aug 1, 2014

Sugarcane draws heavily from soil and requires corresponding replenishment of nutrients. With the... more Sugarcane draws heavily from soil and requires corresponding replenishment of nutrients. With the increasingly crop residue and farm waste, finding alternative uses for supplementing the soil has become more acute. Long-term use of inorganic fertilizers and pesticides to enhance the productivity of sugarcane results in deterioration of soil quality and the decline in productivity. It also contributes to the accumulation of heavy metals in soil and raising concern about crop production and potential impact on human health. Stubble decline, characterized by progressive reductions of yield in successive crops, is a major constraint on productivity and profitability of the sugarcane industry due to poor soil aeration, drainage, weed competition and Pythium root rot. To facilitate sugarcane cultivation on a sustainable basis, and at the same time obtain product more acceptable in international market, it is advisable to apply biofertilizers and promote organic farming. Application of different biofertilizers such as Azotobacter, Pseudomonas, Azospirillum, Trichoderma, Gliocladium sp. AM fungi (Glomus fasciculatum, Glomus intraradices and Gigaspora albida) and Seaweeds (Caulerpa racemosa, Ulva lactuca, Sargassum wightii, Gelidiella acerosa and Gracilaria edulis), has shown significant improvement in sugarcane yield. Biofertilizers improve soil physical properties, such as porosity, aeration and water infiltration by forming and stabilizing soil aggregates. Composted organic materials have been utilized with varying success for suppression of root rot in sugarcane that would result in increased production and productivity. Studies have also indicated that it is feasible to make a comparable yield of sugarcane by meeting the nutrient demand entirely through organics. The farm produce will not contain traces of hazardous substances and will be accepted across the globe as a premium organic product.

Journal of Pharmacy Research, 2013

Bioremediation is considered as one of the safer, cleaner, cost effective and environmental frien... more Bioremediation is considered as one of the safer, cleaner, cost effective and environmental friendly technology for decontaminating sites which are contaminated with wide range of pollutants. Various industrial and anthropogenic activities resulted in increased contaminated sites due to unawareness regarding production, use and disposal of hazardous substances. The process of bioremediation uses various agents such as bacteria, yeast, fungi, algae and higher plants as major tools in treating oil spills and heavy metals present in the environment. A continuous search for the new biological forms is required to regulate increasing pollution and environmental problems faced by man residing in an area. As microorganism shows wide range of mechanisms, there are still few mechanisms which are not known, therefore bioremediation is still considered as a developing technology. Thus, there is an urgent need to for us to review and modify the available options for environmental clean up. The ...

Rauvolfia serpentina is an important medicinal plant in the pharmaceutical world due to the prese... more Rauvolfia serpentina is an important medicinal plant in the pharmaceutical world due to the presence of its immense therapeutic properties. The plant is known for curing various disorders because of the presence of alkaloids, carbohydrates, flavonoids, glycosides, phlobatannins, phenols, resins, saponins sterols, tannins and terpenes. The plant parts, root and rhizome have been used since centuries in Ayurvedic medicines for curing a large number of diseases such as high blood pressure, mental agitation, epilepsy, traumas, anxiety, excitement, schizophrenia, sedative insomnia and insanity. The plant contains more than 50 different alkaloids which belong to the monoterpenoid indole alkaloid family. The major alkaloids are ajmaline, ajmalicine, ajmalimine, deserpidine, indobine, indobinine, reserpine, reserpiline, rescinnamine, rescinnamidine, serpentine, serpentinine and yohimbine. R. serpentina is also known for its antimicrobial, antifungal, anti-inflammatory, antiproliferative, an...

The global population is expanding day by day, the increase in food demand by the growing populat... more The global population is expanding day by day, the increase in food demand by the growing population poses serious environmental challenges. To satisfy the increasing food supply, a shift in conventional agriculture was observed that lead to expanded agricultural land uses with reduced wildlife and biodiversity. Deterioration of agricultural land has caused overexploitation of forest land by converting natural habitats into managed systems. Life has originated billions of years ago. Since then, there is a continual extinction of over 90% of the species due to various factors such as increased human population, unsustainable resource consumption, habitat fragmentation, habitat degradation, alien species invasion, pollution, monoculture practices, climate change, loss of forest cover etc. Food, fodder, fuel, medicines, wood, crop plants are some of the natural resources received from the environment. Biodiversity also provides an ecosystem, social, and spiritual services to mankind. W...

Journal of Integrated Science and Technology, Jan 10, 2014

β-Secretase or BACE-1 is a popular target for the treatment of Alzheimer disease (AD) and respons... more β-Secretase or BACE-1 is a popular target for the treatment of Alzheimer disease (AD) and responsible for the formation of amyloid-β peptide. In recent years BACE-1 has emerged as one of the best characterized targets for Alzheimer therapy. The inhibition of BACE-1 activity is a crucial step for the treatment of AD. This mini-review summarizes some popular BACE-1 inhibitors possessing hydroxyethylamine and peptide scaffolds.

Current Nutrition & Food Science, 2014

Advanced Science, Engineering and Medicine, 2014

American Journal of Plant Sciences, 2013

Ozone (O 3) is a stratospheric layer that plays important role in providing support to humans for... more Ozone (O 3) is a stratospheric layer that plays important role in providing support to humans for their survival. It is an essential factor for many global, biological and environmental phenomena. The ultraviolet (UV) rays emitted from sun are captured by ozone and thereby provide a stable ontological structure in the biosphere. Various anthropogenic activities such as emissions of CFCs, HCFCs and other organo-halogens lead to the depletion of ozone. The ozone depletion resulted in secondary production of an ozone layer near the ground (terrestrial ozone layer), which is responsible for adverse effects on plants, humans and environment with increased number of bronchial diseases in humans. The mutations caused by UV rays result in variation in morphogenic traits of plants which ultimately decreases crop productivity. However, UV radiation is required in optimum intensity for both plants and animals. This review takes into an account the wide ranging effects of ozone depletion with a majority of them being detrimental to the plant system.