bin han - Academia.edu (original) (raw)
Papers by bin han
Annals of Translational Medicine
Background: Esophageal cancer is a malignant tumor that seriously endangers human health. Compare... more Background: Esophageal cancer is a malignant tumor that seriously endangers human health. Compared with surgery alone, enhanced recovery after surgery (ERAS) has been widely used in clinical practice because it can improve perioperative care, minimize complications, and accelerate the recovery of esophageal cancer patients. However, there is a lack of data supporting the cost-effectiveness of ERAS. Methods: This retrospective cohort study included 968 esophageal cancer patients according to the predetermined inclusion and exclusion criteria. Based on the Chinese expert consensus and guidelines, we improved the ERAS protocols consisting of 17 core measures. Subjects receiving >60% of the ERAS optimization measures were classified as the ERAS group, while those receiving <60% were classified as the pre-ERAS group. The demographic information, clinical and cost data of these patients were collected from the medical records. Based on the data distribution, the clinical effects and costs between the two groups were examined using the independent-sample t-test, the rank sum test, or the chi-square test. The effect of cost-effectiveness ratio calculation was measured by the disease cure rate obtained from the discharge report. Results: A total of 374 and 594 patients were included in the ERAS and pre-ERAS groups, respectively, and there were no significant differences in gender, American Society of Anesthesiologists (ASA) grade, tumor location, tumor stage, and other basic conditions between the two groups. The intraoperative blood loss, hospital stays, postoperative rehabilitation time, postoperative complications, and the number of secondary admissions within 30 days postoperatively of the ERAS group were lower than those of the pre-ERAS group (P<0.05). Compared with the pre-ERAS group, participants in the ERAS group had lower direct medical cost, direct non-medical cost, and indirect cost (P<0.05). Moreover, the cost-effectiveness ratio of the ERAS group (118,439.0 Yuan) was lower than that of the pre-ERAS group (143,369.0 Yuan) with respect to the cure rate. Conclusions: The study demonstrated that compared with pre-ERAS, the application of ERAS in esophageal cancer patients may accelerate postoperative rehabilitation, reduce the length of hospital stays and postoperative complications, and have better cost-effectiveness, highlighting the potential of ERAS to improve the quality of medical care.
Annals of Translational Medicine, Mar 1, 2022
Background: The imbalanced allocation of medical resources leads to the occurrence of cross-regio... more Background: The imbalanced allocation of medical resources leads to the occurrence of cross-regional healthcare-seeking in China. Due to the low cure rate, advanced colorectal cancer (CRC) patients may seek cross-regional healthcare for high-level medical facilities. Investigating status of cross-regional healthcareseeking and its associated factors among advanced CRC patients is important for policymakers to understand access to health services and improve the quality of oncology services. Methods: From March 2020 to March 2021, a cross-sectional, nationwide , hospital-based, multi-center survey was conducted. Nineteen hospitals in seven regions were selected by multi-stage stratified sampling. Results: A total of 4,589 individuals with advanced CRC were included. The average age of the patients was 60.1±11.6 years, and 59.5% were males. About 37.5% of the patients suffered from metastatic CRC at first diagnosis. Approximately 36.5% of the patients had sought cross-regional health care previously, and among them, 31.9% had encountered problems. The most common problems included complicated procedures (95.3%), unreimbursed expenses of outpatient service (71.0%), and reimbursement delay (59.4%). Logistic regression analysis showed that patients who completed undergraduate or above [odds ratio (OR) =1.40, 95% confidence interval (CI): 1.13-1.73], had an annual household income of more than 100,000 Chinse Yuan (CNY) (OR =1.46, 95% CI: 1.21-1.78), and had metastasis at diagnosis (OR =1.33, 95% CI: 1.18-1.51) were more likely to seek cross-regional health care. Conclusions: About one third of advanced CRC patients seek cross-regional health care, and 31.9% had encountered problems. There is a need to simplify procedures of reimbursement, optimize direct settlement system and referral mechanisms in order to improve the equality of health services.
Chinese Journal of Laboratory Medicine, 2008
Objective To investigate the clinical value of tissue polypeptide specific antigen(TPS),neuron-sp... more Objective To investigate the clinical value of tissue polypeptide specific antigen(TPS),neuron-specific enolase(NSE),carcinoembryonie antigen(CEA)and CA125 in serum of small cell lung cancer(SCLC)patients and its significance in diagnosis and disease monitoring.Methods Serum leveh of TPS was detected using ELISA and serum levels of NSE,CA125 and CEA was detected using ECLin 27 1 SCLC patients.80 pulmonary benign disease patients and 224 normal healthy people.Diagnostic values of these tumor markers were analyzed by receiver operative characteristic(ROC)curve.Results The levels of TPS,NSE,CA125 and CEA iu the serum of SCLC group were signifieanfly higher than those in pulmonary benign disease and healthy group(Z＞1.90,P＜0.01).The levels of TPS and NSE in the serum of extensive stage small cell lung cancer(ESCLC)patients were significantly higher than those in limited stage small cell lung cancer(LSCLC)(Z=2.69,2.27,P=0.009,0.02 respectively).,The level of TPS and NSE showed statistical...
Chinese Journal of Laboratory Medicine, 2018
Objective To investigate the clinical significance of HCV antibody S/CO values in active HCV infe... more Objective To investigate the clinical significance of HCV antibody S/CO values in active HCV infection diagnosis in cancer patients. Methods 390 cancer patients were enrolled from Cancer Hospital Chinese Academy of Medical Sciences between January 2013 and April 2015. All of the cancer patients had pathological diagnosis, including 240 males and 150 females, aged from 25 to 83 years old. HCV antibody and HCV RNA levels were detected using the Abbott i2000 immunity analyzer and Roche LC480 real-time fluorescent quantitative PCR machine, respectively. The relationship between HCV antibody S/CO value and RNA level was analyzed in the group of HCC and non-HCC patients. Results There were obvious statistical differences in age (P=0.004), gender (P<0.001) and HCV antibody levels (P<0.001) between the group of HCC and non-HCC patients. There was no statistical difference in distribution of RNA positive rate between the two groups (P=0.528). Using ROC curve analysis, the best cut-off ...
Chinese Journal of Laboratory Medicine, 2011
Objective To evaluate the clinical significance of serum levels of ProGRP, TPS and NSE in diagnos... more Objective To evaluate the clinical significance of serum levels of ProGRP, TPS and NSE in diagnosis and therapy monitoring in small cell lung cancer patients. Methods The levels of serum ProGRP, TPS and NSE in 51 SCLC patients (SCLC group), 60 benign pulmonary disease patients (benign disease group ) and 60 healthy people (healthy group ) were determined using chemiluminescent immunoassay, ELISA and electrochemiluminescent immunoassay respectively. Blood samples were collected and detected prior to therapy, before the second course of chemotherapy and the third course of chemotherapy consecutively in all the 51 SCLC patients. Results The serum ProGRP, TPS and NSE concentrations prior to chemotherapy in limited stage SCLC (LSCLC) were 136. 9(22.8-631.7)ng/L, 78. 2(56.4-114.6) U/L and 28.1(20.9-46.1)μg/L, respectively; And in extensive stage SCLC patients (ESCLC) were 1 106.6(41.2-2161.1) ng/L, 230. 9( 143.5-259.0) U/L and 81.1 (34.3-140.0)μg/L, respectively. The serum concentrations ...
Chinese Journal of Laboratory Medicine, 2010
Objective To explore the expression of serum S100BB protein in brain metastases from lung cancer.... more Objective To explore the expression of serum S100BB protein in brain metastases from lung cancer.Methods The levels of serum S100BB protein were measured in 43 brain metastases from lung cancer patients(tumor less than 1 cm:12 cases,1-2 cm:9 cases,greater than 2 cm:17 cases and unknown size:5 cases),44 lung cancer patients and 45 pneumonia patients as well as control subjects using enzyme-linked immunosorbent assay.The association of serum S100BB protein with brain metastases from lung cancer patients was analyzed.Results The median value of semm S100BB protein,which was higher in the lung cancer patients with brain metastases[42.8(38.56-121.70)ng/L]than that in lung cancer patients[34.09(27.38-43.89)ng/L],in pneumonia patients[31.11(26.79-37.15)ng/L]and in control subjects[30.97(7.27-35.84)ng/L,U=422.5,325.5 and 237.5,respectively,P 0.05).Conclusions The serum S100BB protein is valuable in auxiliary diagnosis of brain metastases in Lung cancer patients.However,the size of brain met...
Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011
OBJECTIVE To investigate the clinical value of combination of human epididymis protein 4 (HE4), C... more OBJECTIVE To investigate the clinical value of combination of human epididymis protein 4 (HE4), CA125 and the Risk of Ovarian Malignancy Algorithm (ROMA) in diagnosis of ovarian carcinoma. METHODS To detect the serum concentration of HE4 using ELISA and CA125 using ECL in patients of ovarian carcinoma group (n = 119), borderline ovarian tumor group (n = 36), benign ovarian neoplasm group (n = 96) and female healthy control group (n = 53). The ROMA based on the serum level of CA125, HE4 and a woman's menopausal status was used to calculate the predicted probability (PP) and diagnostic results of ovarian cancers. RESULTS The receiver operating characteristic (ROC) analysis showed the cut-off value was 67.3 pmol/L (the AUC was 0.906, the sensitivity was 80.7% and specificity was 94.6%). The serum levels of HE4 and CA125 in the ovarian carcinoma group were significantly higher than that in the borderline ovarian tumor group, benign ovarian neoplasm group and female healthy control g...
Mechanical Systems and Signal Processing, 2018
Six axis force/torque sensors with characteristics of high precision, high reliability, and high ... more Six axis force/torque sensors with characteristics of high precision, high reliability, and high dynamic, have become one of the major bottlenecks restricting the development of the robot. Aiming at the existing decoupling problem of piezoelectric six axis force/torque sensor with four point support structure, this paper presents the research and application on static decoupling method. Firstly, initial experimental data for decoupling of piezoelectric six axis force/torque sensor is obtained by making a calibration experiment. And then, experimental data are analyzed according to evaluate indicator. The linear decoupling algorithm based on the least square (LS) method is performed. Fusion decoupling algorithm based on Least Square Support Vector Machine Regression (LSSVR) is adopted to optimize multi-dimensional nonlinear characteristics of sensor output. The mapping relation between input and output of the sensor is identified. After LSSVM fusion algorithm decoupling, the maximum nonlinear error and cross coupling error are 0.89%, and 0.1%, respectively. The results show that the decoupling of LSSVR fusion algorithm can reduce the nonlinear error and cross coupling error of the fabricated piezoelectric six axis force/torque sensor. It has important significance to improve the measurement accuracy of robot force feedback with piezoelectric six axis force/torque sensors.
5th IET International Conference on Renewable Power Generation (RPG) 2016, 2016
2013 IEEE Wireless Communications and Networking Conference (WCNC), 2013
ABSTRACT In this paper, a network coding broadcast (NC-BC) scheme is proposed to improve the spec... more ABSTRACT In this paper, a network coding broadcast (NC-BC) scheme is proposed to improve the spectral efficiency for multipleinput and multiple-output (MIMO) transmissions. Particularly by network coding the base station broadcast message with each user message respectively, NC-BC can save the radio resource allocated for base station broadcasting, which is necessary in conventional time division-based scheme. Moreover, the iterative precoding design for NC-BC is studied for approaching the optimal performance, and the sub-optimal precoding design with low complexity is also provided. The simulation results show that the proposed NC-BC scheme with precoding optimization can further improve the system transmission performance.
Journal of Separation Science, 2009
Microchip free flow IEF (lFFIEF) with monolithic IPG was proposed for protein prefractionation. T... more Microchip free flow IEF (lFFIEF) with monolithic IPG was proposed for protein prefractionation. The monolithic materials were first prepared by UV irradiation in a microchamber of 43 mm length, 23 mm width, and 38 lm depth. Carrier ampholytes (CAs) were further immobilized on the monolith by chemical bonding, to form a stable pH gradient. By such a technique, the continuous introduction of CAs in traditional lFFIEF could be avoided, not only to decrease the operation cost, but also to avoid the interference of CAs for the further protein identification by MS/MS. With a fluorescence microscope as the detector, under the optimal conditions, the separation of FITC labeled b-lactoglobulin and carbonic anhydrase, with 0.9 unit difference on pI, was achieved with good reproducibility. The experimental results demonstrated that under the experimental conditions we applied, the separation mechanism of lFFIEF with M-IPG materials might be the cooperative effects of IEF and CZE, and the former one plays a predominant role.
International Journal of Communication Systems, 2012
In this paper, we propose an N th best relay selection (N th-RS) scheme for analog network coding... more In this paper, we propose an N th best relay selection (N th-RS) scheme for analog network coding in twoway relay systems. In traditional two-way single-relay selection schemes, only the best one is selected to forward network-coded signals. However, in practical applications, the best relay may be unavailable because of the scheduling or overload constraints. In this case, we investigate a more general scheme, where the N th best but available relay is selected. To evaluate the transmission of reliability, the expression of outage probability in exponential-integral form and its asymptotic expression in closed form are presented. Moreover, the upper bound and lower bound of outage probability are also derived. The analysis reveals that the diversity order of N th-RS equals to (M N C 1), where M is the number of relay nodes, and the results are verified by simulations. In order to improve system performance, transmit power between sources and relay is optimally allocated to minimize the upper bound of outage probability under total power constraint. Simulation results show that N th-RS scheme with proposed power allocation can achieve substantial improvement over equal power allocation scheme.
Analytica Chimica Acta, 2009
A novel and sensitive electrochemical DNA biosensor has been developed for the detection of DNA h... more A novel and sensitive electrochemical DNA biosensor has been developed for the detection of DNA hybridization. The biosensor was proposed by using copper(II) complex of Luteolin C 30 H 18 CuO 12 (CuL 2) as an electroactive indicator based on silver nanoparticles and multi-walled carbon nanotubes (Ag/MWCNTs) modified glassy carbon electrode (GCE). In this method, the 4-aminobenzoic acid (4-ABA) and Ag nanoparticles were covalently grafted on MWCNTs to form Ag/4-ABA/MWCNTs. The proposed method dramatically increased DNA attachment quantity and complementary ssDNA detection sensitivity for its large surface area and good charge-transport characteristics. DNA hybridization detection was performed using CuL 2 as an electroactive indicator. The CuL 2 was synthesized and characterized using elemental analysis (EA) and IR spectroscopy. Cyclic voltammetry (CV) and fluorescence spectroscopy were used to investigate the interaction between CuL 2 and ds-oligonucleotides (dsDNA). It was revealed that CuL 2 presented high electrochemical activity on GCE, and it could be intercalated into the double helices of dsDNA. The target ssDNA of the human hepatitis B virus (HBV) was quantified in a linear range from 3.23 × 10 −12 to 5.31 × 10 −9 M (r = 0.9983). A detection limit of 6.46 × 10 −13 M (3 , n = 11) was achieved.
Annals of Translational Medicine
Background: Esophageal cancer is a malignant tumor that seriously endangers human health. Compare... more Background: Esophageal cancer is a malignant tumor that seriously endangers human health. Compared with surgery alone, enhanced recovery after surgery (ERAS) has been widely used in clinical practice because it can improve perioperative care, minimize complications, and accelerate the recovery of esophageal cancer patients. However, there is a lack of data supporting the cost-effectiveness of ERAS. Methods: This retrospective cohort study included 968 esophageal cancer patients according to the predetermined inclusion and exclusion criteria. Based on the Chinese expert consensus and guidelines, we improved the ERAS protocols consisting of 17 core measures. Subjects receiving >60% of the ERAS optimization measures were classified as the ERAS group, while those receiving <60% were classified as the pre-ERAS group. The demographic information, clinical and cost data of these patients were collected from the medical records. Based on the data distribution, the clinical effects and costs between the two groups were examined using the independent-sample t-test, the rank sum test, or the chi-square test. The effect of cost-effectiveness ratio calculation was measured by the disease cure rate obtained from the discharge report. Results: A total of 374 and 594 patients were included in the ERAS and pre-ERAS groups, respectively, and there were no significant differences in gender, American Society of Anesthesiologists (ASA) grade, tumor location, tumor stage, and other basic conditions between the two groups. The intraoperative blood loss, hospital stays, postoperative rehabilitation time, postoperative complications, and the number of secondary admissions within 30 days postoperatively of the ERAS group were lower than those of the pre-ERAS group (P<0.05). Compared with the pre-ERAS group, participants in the ERAS group had lower direct medical cost, direct non-medical cost, and indirect cost (P<0.05). Moreover, the cost-effectiveness ratio of the ERAS group (118,439.0 Yuan) was lower than that of the pre-ERAS group (143,369.0 Yuan) with respect to the cure rate. Conclusions: The study demonstrated that compared with pre-ERAS, the application of ERAS in esophageal cancer patients may accelerate postoperative rehabilitation, reduce the length of hospital stays and postoperative complications, and have better cost-effectiveness, highlighting the potential of ERAS to improve the quality of medical care.
Annals of Translational Medicine, Mar 1, 2022
Background: The imbalanced allocation of medical resources leads to the occurrence of cross-regio... more Background: The imbalanced allocation of medical resources leads to the occurrence of cross-regional healthcare-seeking in China. Due to the low cure rate, advanced colorectal cancer (CRC) patients may seek cross-regional healthcare for high-level medical facilities. Investigating status of cross-regional healthcareseeking and its associated factors among advanced CRC patients is important for policymakers to understand access to health services and improve the quality of oncology services. Methods: From March 2020 to March 2021, a cross-sectional, nationwide , hospital-based, multi-center survey was conducted. Nineteen hospitals in seven regions were selected by multi-stage stratified sampling. Results: A total of 4,589 individuals with advanced CRC were included. The average age of the patients was 60.1±11.6 years, and 59.5% were males. About 37.5% of the patients suffered from metastatic CRC at first diagnosis. Approximately 36.5% of the patients had sought cross-regional health care previously, and among them, 31.9% had encountered problems. The most common problems included complicated procedures (95.3%), unreimbursed expenses of outpatient service (71.0%), and reimbursement delay (59.4%). Logistic regression analysis showed that patients who completed undergraduate or above [odds ratio (OR) =1.40, 95% confidence interval (CI): 1.13-1.73], had an annual household income of more than 100,000 Chinse Yuan (CNY) (OR =1.46, 95% CI: 1.21-1.78), and had metastasis at diagnosis (OR =1.33, 95% CI: 1.18-1.51) were more likely to seek cross-regional health care. Conclusions: About one third of advanced CRC patients seek cross-regional health care, and 31.9% had encountered problems. There is a need to simplify procedures of reimbursement, optimize direct settlement system and referral mechanisms in order to improve the equality of health services.
Chinese Journal of Laboratory Medicine, 2008
Objective To investigate the clinical value of tissue polypeptide specific antigen(TPS),neuron-sp... more Objective To investigate the clinical value of tissue polypeptide specific antigen(TPS),neuron-specific enolase(NSE),carcinoembryonie antigen(CEA)and CA125 in serum of small cell lung cancer(SCLC)patients and its significance in diagnosis and disease monitoring.Methods Serum leveh of TPS was detected using ELISA and serum levels of NSE,CA125 and CEA was detected using ECLin 27 1 SCLC patients.80 pulmonary benign disease patients and 224 normal healthy people.Diagnostic values of these tumor markers were analyzed by receiver operative characteristic(ROC)curve.Results The levels of TPS,NSE,CA125 and CEA iu the serum of SCLC group were signifieanfly higher than those in pulmonary benign disease and healthy group(Z＞1.90,P＜0.01).The levels of TPS and NSE in the serum of extensive stage small cell lung cancer(ESCLC)patients were significantly higher than those in limited stage small cell lung cancer(LSCLC)(Z=2.69,2.27,P=0.009,0.02 respectively).,The level of TPS and NSE showed statistical...
Chinese Journal of Laboratory Medicine, 2018
Objective To investigate the clinical significance of HCV antibody S/CO values in active HCV infe... more Objective To investigate the clinical significance of HCV antibody S/CO values in active HCV infection diagnosis in cancer patients. Methods 390 cancer patients were enrolled from Cancer Hospital Chinese Academy of Medical Sciences between January 2013 and April 2015. All of the cancer patients had pathological diagnosis, including 240 males and 150 females, aged from 25 to 83 years old. HCV antibody and HCV RNA levels were detected using the Abbott i2000 immunity analyzer and Roche LC480 real-time fluorescent quantitative PCR machine, respectively. The relationship between HCV antibody S/CO value and RNA level was analyzed in the group of HCC and non-HCC patients. Results There were obvious statistical differences in age (P=0.004), gender (P<0.001) and HCV antibody levels (P<0.001) between the group of HCC and non-HCC patients. There was no statistical difference in distribution of RNA positive rate between the two groups (P=0.528). Using ROC curve analysis, the best cut-off ...
Chinese Journal of Laboratory Medicine, 2011
Objective To evaluate the clinical significance of serum levels of ProGRP, TPS and NSE in diagnos... more Objective To evaluate the clinical significance of serum levels of ProGRP, TPS and NSE in diagnosis and therapy monitoring in small cell lung cancer patients. Methods The levels of serum ProGRP, TPS and NSE in 51 SCLC patients (SCLC group), 60 benign pulmonary disease patients (benign disease group ) and 60 healthy people (healthy group ) were determined using chemiluminescent immunoassay, ELISA and electrochemiluminescent immunoassay respectively. Blood samples were collected and detected prior to therapy, before the second course of chemotherapy and the third course of chemotherapy consecutively in all the 51 SCLC patients. Results The serum ProGRP, TPS and NSE concentrations prior to chemotherapy in limited stage SCLC (LSCLC) were 136. 9(22.8-631.7)ng/L, 78. 2(56.4-114.6) U/L and 28.1(20.9-46.1)μg/L, respectively; And in extensive stage SCLC patients (ESCLC) were 1 106.6(41.2-2161.1) ng/L, 230. 9( 143.5-259.0) U/L and 81.1 (34.3-140.0)μg/L, respectively. The serum concentrations ...
Chinese Journal of Laboratory Medicine, 2010
Objective To explore the expression of serum S100BB protein in brain metastases from lung cancer.... more Objective To explore the expression of serum S100BB protein in brain metastases from lung cancer.Methods The levels of serum S100BB protein were measured in 43 brain metastases from lung cancer patients(tumor less than 1 cm:12 cases,1-2 cm:9 cases,greater than 2 cm:17 cases and unknown size:5 cases),44 lung cancer patients and 45 pneumonia patients as well as control subjects using enzyme-linked immunosorbent assay.The association of serum S100BB protein with brain metastases from lung cancer patients was analyzed.Results The median value of semm S100BB protein,which was higher in the lung cancer patients with brain metastases[42.8(38.56-121.70)ng/L]than that in lung cancer patients[34.09(27.38-43.89)ng/L],in pneumonia patients[31.11(26.79-37.15)ng/L]and in control subjects[30.97(7.27-35.84)ng/L,U=422.5,325.5 and 237.5,respectively,P 0.05).Conclusions The serum S100BB protein is valuable in auxiliary diagnosis of brain metastases in Lung cancer patients.However,the size of brain met...
Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011
OBJECTIVE To investigate the clinical value of combination of human epididymis protein 4 (HE4), C... more OBJECTIVE To investigate the clinical value of combination of human epididymis protein 4 (HE4), CA125 and the Risk of Ovarian Malignancy Algorithm (ROMA) in diagnosis of ovarian carcinoma. METHODS To detect the serum concentration of HE4 using ELISA and CA125 using ECL in patients of ovarian carcinoma group (n = 119), borderline ovarian tumor group (n = 36), benign ovarian neoplasm group (n = 96) and female healthy control group (n = 53). The ROMA based on the serum level of CA125, HE4 and a woman's menopausal status was used to calculate the predicted probability (PP) and diagnostic results of ovarian cancers. RESULTS The receiver operating characteristic (ROC) analysis showed the cut-off value was 67.3 pmol/L (the AUC was 0.906, the sensitivity was 80.7% and specificity was 94.6%). The serum levels of HE4 and CA125 in the ovarian carcinoma group were significantly higher than that in the borderline ovarian tumor group, benign ovarian neoplasm group and female healthy control g...
Mechanical Systems and Signal Processing, 2018
Six axis force/torque sensors with characteristics of high precision, high reliability, and high ... more Six axis force/torque sensors with characteristics of high precision, high reliability, and high dynamic, have become one of the major bottlenecks restricting the development of the robot. Aiming at the existing decoupling problem of piezoelectric six axis force/torque sensor with four point support structure, this paper presents the research and application on static decoupling method. Firstly, initial experimental data for decoupling of piezoelectric six axis force/torque sensor is obtained by making a calibration experiment. And then, experimental data are analyzed according to evaluate indicator. The linear decoupling algorithm based on the least square (LS) method is performed. Fusion decoupling algorithm based on Least Square Support Vector Machine Regression (LSSVR) is adopted to optimize multi-dimensional nonlinear characteristics of sensor output. The mapping relation between input and output of the sensor is identified. After LSSVM fusion algorithm decoupling, the maximum nonlinear error and cross coupling error are 0.89%, and 0.1%, respectively. The results show that the decoupling of LSSVR fusion algorithm can reduce the nonlinear error and cross coupling error of the fabricated piezoelectric six axis force/torque sensor. It has important significance to improve the measurement accuracy of robot force feedback with piezoelectric six axis force/torque sensors.
5th IET International Conference on Renewable Power Generation (RPG) 2016, 2016
2013 IEEE Wireless Communications and Networking Conference (WCNC), 2013
ABSTRACT In this paper, a network coding broadcast (NC-BC) scheme is proposed to improve the spec... more ABSTRACT In this paper, a network coding broadcast (NC-BC) scheme is proposed to improve the spectral efficiency for multipleinput and multiple-output (MIMO) transmissions. Particularly by network coding the base station broadcast message with each user message respectively, NC-BC can save the radio resource allocated for base station broadcasting, which is necessary in conventional time division-based scheme. Moreover, the iterative precoding design for NC-BC is studied for approaching the optimal performance, and the sub-optimal precoding design with low complexity is also provided. The simulation results show that the proposed NC-BC scheme with precoding optimization can further improve the system transmission performance.
Journal of Separation Science, 2009
Microchip free flow IEF (lFFIEF) with monolithic IPG was proposed for protein prefractionation. T... more Microchip free flow IEF (lFFIEF) with monolithic IPG was proposed for protein prefractionation. The monolithic materials were first prepared by UV irradiation in a microchamber of 43 mm length, 23 mm width, and 38 lm depth. Carrier ampholytes (CAs) were further immobilized on the monolith by chemical bonding, to form a stable pH gradient. By such a technique, the continuous introduction of CAs in traditional lFFIEF could be avoided, not only to decrease the operation cost, but also to avoid the interference of CAs for the further protein identification by MS/MS. With a fluorescence microscope as the detector, under the optimal conditions, the separation of FITC labeled b-lactoglobulin and carbonic anhydrase, with 0.9 unit difference on pI, was achieved with good reproducibility. The experimental results demonstrated that under the experimental conditions we applied, the separation mechanism of lFFIEF with M-IPG materials might be the cooperative effects of IEF and CZE, and the former one plays a predominant role.
International Journal of Communication Systems, 2012
In this paper, we propose an N th best relay selection (N th-RS) scheme for analog network coding... more In this paper, we propose an N th best relay selection (N th-RS) scheme for analog network coding in twoway relay systems. In traditional two-way single-relay selection schemes, only the best one is selected to forward network-coded signals. However, in practical applications, the best relay may be unavailable because of the scheduling or overload constraints. In this case, we investigate a more general scheme, where the N th best but available relay is selected. To evaluate the transmission of reliability, the expression of outage probability in exponential-integral form and its asymptotic expression in closed form are presented. Moreover, the upper bound and lower bound of outage probability are also derived. The analysis reveals that the diversity order of N th-RS equals to (M N C 1), where M is the number of relay nodes, and the results are verified by simulations. In order to improve system performance, transmit power between sources and relay is optimally allocated to minimize the upper bound of outage probability under total power constraint. Simulation results show that N th-RS scheme with proposed power allocation can achieve substantial improvement over equal power allocation scheme.
Analytica Chimica Acta, 2009
A novel and sensitive electrochemical DNA biosensor has been developed for the detection of DNA h... more A novel and sensitive electrochemical DNA biosensor has been developed for the detection of DNA hybridization. The biosensor was proposed by using copper(II) complex of Luteolin C 30 H 18 CuO 12 (CuL 2) as an electroactive indicator based on silver nanoparticles and multi-walled carbon nanotubes (Ag/MWCNTs) modified glassy carbon electrode (GCE). In this method, the 4-aminobenzoic acid (4-ABA) and Ag nanoparticles were covalently grafted on MWCNTs to form Ag/4-ABA/MWCNTs. The proposed method dramatically increased DNA attachment quantity and complementary ssDNA detection sensitivity for its large surface area and good charge-transport characteristics. DNA hybridization detection was performed using CuL 2 as an electroactive indicator. The CuL 2 was synthesized and characterized using elemental analysis (EA) and IR spectroscopy. Cyclic voltammetry (CV) and fluorescence spectroscopy were used to investigate the interaction between CuL 2 and ds-oligonucleotides (dsDNA). It was revealed that CuL 2 presented high electrochemical activity on GCE, and it could be intercalated into the double helices of dsDNA. The target ssDNA of the human hepatitis B virus (HBV) was quantified in a linear range from 3.23 × 10 −12 to 5.31 × 10 −9 M (r = 0.9983). A detection limit of 6.46 × 10 −13 M (3 , n = 11) was achieved.