behzad nazemroaya - Academia.edu (original) (raw)
Papers by behzad nazemroaya
Pakistan journal of ophthalmology, Jun 30, 2023
Purpose: To compare the hemodynamic effects of low-dose ketamine combined with dexmedetomidine v... more Purpose: To compare the hemodynamic effects of low-dose ketamine combined with dexmedetomidine versus propofol in phacoemulsification under local anesthesia. Place and Duration of Study: School of Medicine, Isfahan University of Medical Sciences during 2020-2021. Methods: Sixty patients admitted for cataract surgery were included. Those with history of systemic diseases, insufficient pupil dilation, sensitivity to drugs and uncooperative patients were excluded. Participants were randomly allocated to two groups; group which was administered ketamine with dexmedetomidine (Ketodex) and group which was given ketamine with propofol (Ketofel). Effect on blood pressure, pulse and sedation was recorded. Results: Mean age was 65 ± 9.9 years. Sixty-five were females. Ketodex increased the risk of hemodynamic disorders compared to Ketofel (P = 0.04). The risk of nausea and vomiting was higher in the Ketodex group although not significant. The effect of drug course on heart rate, blood pressure and sedation was significant in both groups (P < 0.05). Neither at baseline, nor in the 1st and 5th minutes of surgery, was the mean arterial pressure (MAP) was significantly different between the two groups. From 10th minute of surgery until the end of surgery and from the beginning of recovery until the 30th minute of recovery, the MAP and pulse rate were higher in Ketofol group. Sedation effect during surgery was higher in the Ketodex group compared to the Ketofol group, and the difference was statistically significant at minutes 10, 20 and 30 of surgery. Conclusion: There is higher effect of sedation and fewer side effects of ketamine-dexmedetomidine combination compared to the ketamine-propofol combination.
DOAJ (DOAJ: Directory of Open Access Journals), Aug 1, 2022
DOAJ (DOAJ: Directory of Open Access Journals), Aug 1, 2021
Journal of Cardiovascular and Thoracic Research
Introduction: Providing a stable hemodynamic in extubation is important. We aimed to compare the ... more Introduction: Providing a stable hemodynamic in extubation is important. We aimed to compare the effect of two different doses of intravenous labetalol on the cardiovascular response to endotracheal extubation. Methods: This double-blind randomized trial was performed in 2019-2020 in Isfahan on 72 patients under general anesthesia. Patients using Random Allocation software were divided into three groups and received 0.1 mg/ kg or 0.2 mg/kg labetalol and normal saline intravenously 10 min before extubation. Hemodynamic variables including heart rate (HR), Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and peripheral blood oxygen saturation(SPO2) was measured for each patient before induction of anesthesia and 1, 3, 5 and 10 minutes after extubation. Results: SBP changes were significantly different between the three groups at 1, 3, 5 minutes after extubation (P=0.036, P=0.009, P=0.005 respectively) unlike the other two groups, patients wh...
Journal of Emergency Practice and Trauma
Objective: In general, spinal fusion surgery causes heavy bleeding. The purpose of this study was... more Objective: In general, spinal fusion surgery causes heavy bleeding. The purpose of this study was to evaluate the use of two different doses of magnesium sulfate to control the bleeding in lumbar fusion surgery. Methods: This study was carried out as a randomized double-blinded clinical trial in 2020 in Al-Zahra hospital in Isfahan. The participants were 60 patients selected using inclusion and exclusion criteria and were randomly allocated into three groups. In the first group, 50 mg/kg and in the second group, 40 mg/kg magnesium sulfate was infused. The third group received normal saline. From the beginning of anesthesia, heart rate, diastolic and systolic blood pressure, respiratory rate and blood oxygen saturation percentage were monitored and logged every 30 minutes during the operation and recovery. The volume of bleeding during the operation was calculated by counting the number of gauzes used and the amount of suctioned blood during the operation. Other required information ...
DOAJ (DOAJ: Directory of Open Access Journals), Nov 1, 2022
Advanced Biomedical Research
Advanced Biomedical Research
BMC Nutrition
Background COVID-19 is a very harmful pandemic, and its recovery process is highly influenced by ... more Background COVID-19 is a very harmful pandemic, and its recovery process is highly influenced by nutritional status; however, an appropriate nutritional scale has not yet been proposed for these patients. Therefore, the purpose of this study was to evaluate the effectiveness of the modified Nutrition Risk in the Critically ill (mNUTRIC) score in critically ill patients affected by COVID-19 admitted to the intensive care unit (ICU). Material and methods This was a cross-sectional study performed on 204 critically ill patients affected by COVID-19 admitted to the ICU wards. Evaluated indicators include the mNUTRIC Score as well as demographic, and biochemical indicators. Results A high percentage of COVID-19 patients (67.2%) had severe disease. Hospital and ICU stay (p > 0.001) and PH (p > 0.001) values were significantly lower in non-survivors than in survivors. mNUTRIC score (p > 0.001), PCO2 (p = 0.003), and CRP levels (p = 0.021) were significantly higher in non-survivors...
Journal of Iranian Medical Council
Background: The lack of any definitive treatment of COVID-19 has caused a great deal of stress in... more Background: The lack of any definitive treatment of COVID-19 has caused a great deal of stress in communities, especially for those fighting in the front line. In the present study, job stress of medical staff working in Intensive Care Units (ICUs) of patients with COVID-19 was evaluated and compared with staff working in non-COVID-19 ICUs. Methods: This study was performed in Iran with a study population of 80 staff members including nurses, paramedics, supervisors and other medical staff working in ICUs of COVID-19 and non-COVID-19 patients. The Osipow questionnaire was used to assess the job stress level. Results: The mean age of medical staff was 29.72±7.58 years old. The stress score of the male medical staff of ICUs of patients with COVID19 was significantly higher than the female staff and the average stress of employees in night shifts (190.60) was significantly higher than those in the morning and afternoon shifts. In the dimension of responsibility for COVID-19 ICU employe...
Advanced Biomedical Research, 2022
DOAJ: Directory of Open Access Journals - DOAJ, Aug 1, 2020
Background Pneumothorax (PTX), pneumomediastinum (PM), and emphysema (EM) are complications of SA... more Background Pneumothorax (PTX), pneumomediastinum (PM), and emphysema (EM) are complications of SARS-CoV-2 infections. Studying these situations' risk factors, complications, and prognosis is essential for early diagnosis during a pandemic. Methods We performed a case-control study of patients diagnosed with coronavirus pneumonia complicated with PTX, PM, and EM compared with patients without these complications to evaluate the risk factors for the incidence and prognosis of patients with pulmonary complications of COVID-19. We used parametric, non-parametric, and regression tests to analyze the data. Results We enrolled 162 patients (81 complicated, 81 uncomplicated). A past medical history of diabetes mellitus (DM), hyperlipidemia (HLP), lung disease, and ischemic heart disease (IHD) was not associated with PTX, PM, and EM in COVID 19 pneumonia (p-value > 0.05). The mortality rate was higher in the case group (69% vs. 15%). Among ventilator modes, 46.2% of intubated patients...
International journal of physiology, pathophysiology and pharmacology, 2022
Archives of Anesthesia and Critical Care
Background: Arterial Blood Gas (ABG) analysis is a commonly ordered test to investigate respirato... more Background: Arterial Blood Gas (ABG) analysis is a commonly ordered test to investigate respiratory, circulatory, and metabolic status in traumatic patients with inappropriate perfusion and ventilation situations. Difficult sampling, hemorrhage risk of arterial puncture, and other vascular complications lead us to use saliva sampling as a safer non-invasive approach to evaluate PaO2, PaCO2, pH, and HCO3 values. This study was aimed to evaluate the correlation of PaO2, PaCO2, pH, and HCO3 values between ABG and saliva gas in traumatic patients under mechanical ventilation. Methods: This was a retrospective cross-sectional study of 18-85-year-old traumatic patients under mechanical ventilation conducted in an academic medical hospital. They were investigated based on age, sex, and ABG values as well their saliva gases values. The Paired t-test, Pearson χ2, and Pearson correlation were used to evaluate the correlation between the gases values in ABG and saliva. Data were analyzed using...
Anesthesiology and Pain Medicine, Apr 30, 2022
Background: Despite all of the benefits provided by laparoscopic cholecystectomy, such as rapid r... more Background: Despite all of the benefits provided by laparoscopic cholecystectomy, such as rapid recovery and shorter hospital stay for patients, the incidence of postoperative nausea and vomiting (PONV) and postoperative pain (POP) still remains high. Objectives: This study was designed to compare the effects of intraperitoneal (IP) and intravenous (IV) dexamethasone on the reduction of PONV and POP. Methods: This prospective, randomized, double-blind clinical trial was conducted on a study population of 86 adult patients who were scheduled for laparoscopic cholecystectomy with the American Society of Anesthesiologists class I-II. The patients were randomized into three groups, namely IP dexamethasone (n = 29), IV dexamethasone (n = 29), and control (n = 28) groups. The patients were followed for clinical outcomes, including PONV, POP, and consumption of antiemetics, and their hemodynamic status during the first 24 hours after the surgery. Results: In the first 24 hours after the operation, no significant differences were observed in nausea (P = 0.41) and vomiting (P = 0.38) between the IP and IV dexamethasone groups. However, there was a lower severity of nausea in the IP group (P = 0.001). Additionally, the visual analog scale score representing POP was significantly reduced in the IP group (P = 0.02). No significant differences in the hemodynamic status were observed after the operation between all the three groups. Conclusions: The administration of 8 mg IP dexamethasone was associated with significantly reduced pain and severity of nausea, but not PONV, after laparoscopic cholecystectomy.
Tehran University Medical Journal TUMS Publications, Aug 10, 2021
<jats:p>Background: One of the complications of ECT treatment is headache. There is a need ... more <jats:p>Background: One of the complications of ECT treatment is headache. There is a need to use sedation during ECT. As a result, midazolam has been used to address a safe and effective strategy in this regard.
 Methods: This study is a double-blind clinical trial that has been performed in three groups: group A, which receives midazolam based on the usual regimen, group B, which receives midazolam after shock, and group C, which is the control group. Patients were asked about headache, nausea, and muscle aches during the recovery time, seizure duration and after becoming fully conscious. Data were analyzed in the PASW version18 software using analysis of variance and repeated measurement tests, ANOVA, independed t and χ2 tests.
 Results: Analysis showed that the frequency of muscle pain after full consciousness in group C was significantly higher than group B, with group B being higher than group A. χ2 test showed that the frequency of headache, cough and nausea in group C was significantly higher than the two groups A and B.
 Conclusion: The result of this research showed that midazolam prodrug plays an effective role in preventing post-ECT complications in children. The effect of midazolam before and after ECT on headache, muscle pain and nausea was investigated and compared with the control group. Also, due to its anterograde amnesia, midazolam can reduce the patient's stress in the next visits, and this issue is even more important when the patient is a child.</jats:p>
JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), Mar 1, 2005
Background: Perioperative pain is prevalent and poorly treated. Apart from that it makes the reco... more Background: Perioperative pain is prevalent and poorly treated. Apart from that it makes the recovery from surgery unpleasent, pain often remains as a residual side effect of surgery, even though the tissue healing is complete. An essential observation is that tissue injury and the resulting nociceptor barrage initiates a cascade of events that can indelibly alter pain perception. Preemptive analgesia is the concept of initiating analgesic therapy before the onset of the noxious stimulus so as to prevent the nociceptor barrage and its ...
Anesthesiology and Pain Medicine, 2021
Objectives: The purpose of this study is a comparison of Valsalva, lidocaine, and Valsalva with a... more Objectives: The purpose of this study is a comparison of Valsalva, lidocaine, and Valsalva with administration of lidocaine to reduce the pain associated with administration of etomidate. Methods: The present study is a clinical trial study. The number of samples in each group was 30 and a total of 90 people were selected. This study was a clinical trial and the subjects were randomly divided into three groups: Group 1: Valsalva, 2: Lidocaine, 3: Valsalva and Lidocaine. Pain due to etomidate was rated on a VAS from 1 (painless) to 3 (worst imaginable pain) and their information was recorded. The collected information was entered into SPSS 22 and analyzed with appropriate statistical tests. Results: A total of 90 subjects participated in the present study and were divided into 3 groups: Valsalva, lidocaine, and Valsalva with lidocaine. No significant difference was observed between demographic variables in the study groups. There was a significant relationship between severity of pai...
Pakistan journal of ophthalmology, Jun 30, 2023
Purpose: To compare the hemodynamic effects of low-dose ketamine combined with dexmedetomidine v... more Purpose: To compare the hemodynamic effects of low-dose ketamine combined with dexmedetomidine versus propofol in phacoemulsification under local anesthesia. Place and Duration of Study: School of Medicine, Isfahan University of Medical Sciences during 2020-2021. Methods: Sixty patients admitted for cataract surgery were included. Those with history of systemic diseases, insufficient pupil dilation, sensitivity to drugs and uncooperative patients were excluded. Participants were randomly allocated to two groups; group which was administered ketamine with dexmedetomidine (Ketodex) and group which was given ketamine with propofol (Ketofel). Effect on blood pressure, pulse and sedation was recorded. Results: Mean age was 65 ± 9.9 years. Sixty-five were females. Ketodex increased the risk of hemodynamic disorders compared to Ketofel (P = 0.04). The risk of nausea and vomiting was higher in the Ketodex group although not significant. The effect of drug course on heart rate, blood pressure and sedation was significant in both groups (P < 0.05). Neither at baseline, nor in the 1st and 5th minutes of surgery, was the mean arterial pressure (MAP) was significantly different between the two groups. From 10th minute of surgery until the end of surgery and from the beginning of recovery until the 30th minute of recovery, the MAP and pulse rate were higher in Ketofol group. Sedation effect during surgery was higher in the Ketodex group compared to the Ketofol group, and the difference was statistically significant at minutes 10, 20 and 30 of surgery. Conclusion: There is higher effect of sedation and fewer side effects of ketamine-dexmedetomidine combination compared to the ketamine-propofol combination.
DOAJ (DOAJ: Directory of Open Access Journals), Aug 1, 2022
DOAJ (DOAJ: Directory of Open Access Journals), Aug 1, 2021
Journal of Cardiovascular and Thoracic Research
Introduction: Providing a stable hemodynamic in extubation is important. We aimed to compare the ... more Introduction: Providing a stable hemodynamic in extubation is important. We aimed to compare the effect of two different doses of intravenous labetalol on the cardiovascular response to endotracheal extubation. Methods: This double-blind randomized trial was performed in 2019-2020 in Isfahan on 72 patients under general anesthesia. Patients using Random Allocation software were divided into three groups and received 0.1 mg/ kg or 0.2 mg/kg labetalol and normal saline intravenously 10 min before extubation. Hemodynamic variables including heart rate (HR), Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and peripheral blood oxygen saturation(SPO2) was measured for each patient before induction of anesthesia and 1, 3, 5 and 10 minutes after extubation. Results: SBP changes were significantly different between the three groups at 1, 3, 5 minutes after extubation (P=0.036, P=0.009, P=0.005 respectively) unlike the other two groups, patients wh...
Journal of Emergency Practice and Trauma
Objective: In general, spinal fusion surgery causes heavy bleeding. The purpose of this study was... more Objective: In general, spinal fusion surgery causes heavy bleeding. The purpose of this study was to evaluate the use of two different doses of magnesium sulfate to control the bleeding in lumbar fusion surgery. Methods: This study was carried out as a randomized double-blinded clinical trial in 2020 in Al-Zahra hospital in Isfahan. The participants were 60 patients selected using inclusion and exclusion criteria and were randomly allocated into three groups. In the first group, 50 mg/kg and in the second group, 40 mg/kg magnesium sulfate was infused. The third group received normal saline. From the beginning of anesthesia, heart rate, diastolic and systolic blood pressure, respiratory rate and blood oxygen saturation percentage were monitored and logged every 30 minutes during the operation and recovery. The volume of bleeding during the operation was calculated by counting the number of gauzes used and the amount of suctioned blood during the operation. Other required information ...
DOAJ (DOAJ: Directory of Open Access Journals), Nov 1, 2022
Advanced Biomedical Research
Advanced Biomedical Research
BMC Nutrition
Background COVID-19 is a very harmful pandemic, and its recovery process is highly influenced by ... more Background COVID-19 is a very harmful pandemic, and its recovery process is highly influenced by nutritional status; however, an appropriate nutritional scale has not yet been proposed for these patients. Therefore, the purpose of this study was to evaluate the effectiveness of the modified Nutrition Risk in the Critically ill (mNUTRIC) score in critically ill patients affected by COVID-19 admitted to the intensive care unit (ICU). Material and methods This was a cross-sectional study performed on 204 critically ill patients affected by COVID-19 admitted to the ICU wards. Evaluated indicators include the mNUTRIC Score as well as demographic, and biochemical indicators. Results A high percentage of COVID-19 patients (67.2%) had severe disease. Hospital and ICU stay (p > 0.001) and PH (p > 0.001) values were significantly lower in non-survivors than in survivors. mNUTRIC score (p > 0.001), PCO2 (p = 0.003), and CRP levels (p = 0.021) were significantly higher in non-survivors...
Journal of Iranian Medical Council
Background: The lack of any definitive treatment of COVID-19 has caused a great deal of stress in... more Background: The lack of any definitive treatment of COVID-19 has caused a great deal of stress in communities, especially for those fighting in the front line. In the present study, job stress of medical staff working in Intensive Care Units (ICUs) of patients with COVID-19 was evaluated and compared with staff working in non-COVID-19 ICUs. Methods: This study was performed in Iran with a study population of 80 staff members including nurses, paramedics, supervisors and other medical staff working in ICUs of COVID-19 and non-COVID-19 patients. The Osipow questionnaire was used to assess the job stress level. Results: The mean age of medical staff was 29.72±7.58 years old. The stress score of the male medical staff of ICUs of patients with COVID19 was significantly higher than the female staff and the average stress of employees in night shifts (190.60) was significantly higher than those in the morning and afternoon shifts. In the dimension of responsibility for COVID-19 ICU employe...
Advanced Biomedical Research, 2022
DOAJ: Directory of Open Access Journals - DOAJ, Aug 1, 2020
Background Pneumothorax (PTX), pneumomediastinum (PM), and emphysema (EM) are complications of SA... more Background Pneumothorax (PTX), pneumomediastinum (PM), and emphysema (EM) are complications of SARS-CoV-2 infections. Studying these situations' risk factors, complications, and prognosis is essential for early diagnosis during a pandemic. Methods We performed a case-control study of patients diagnosed with coronavirus pneumonia complicated with PTX, PM, and EM compared with patients without these complications to evaluate the risk factors for the incidence and prognosis of patients with pulmonary complications of COVID-19. We used parametric, non-parametric, and regression tests to analyze the data. Results We enrolled 162 patients (81 complicated, 81 uncomplicated). A past medical history of diabetes mellitus (DM), hyperlipidemia (HLP), lung disease, and ischemic heart disease (IHD) was not associated with PTX, PM, and EM in COVID 19 pneumonia (p-value > 0.05). The mortality rate was higher in the case group (69% vs. 15%). Among ventilator modes, 46.2% of intubated patients...
International journal of physiology, pathophysiology and pharmacology, 2022
Archives of Anesthesia and Critical Care
Background: Arterial Blood Gas (ABG) analysis is a commonly ordered test to investigate respirato... more Background: Arterial Blood Gas (ABG) analysis is a commonly ordered test to investigate respiratory, circulatory, and metabolic status in traumatic patients with inappropriate perfusion and ventilation situations. Difficult sampling, hemorrhage risk of arterial puncture, and other vascular complications lead us to use saliva sampling as a safer non-invasive approach to evaluate PaO2, PaCO2, pH, and HCO3 values. This study was aimed to evaluate the correlation of PaO2, PaCO2, pH, and HCO3 values between ABG and saliva gas in traumatic patients under mechanical ventilation. Methods: This was a retrospective cross-sectional study of 18-85-year-old traumatic patients under mechanical ventilation conducted in an academic medical hospital. They were investigated based on age, sex, and ABG values as well their saliva gases values. The Paired t-test, Pearson χ2, and Pearson correlation were used to evaluate the correlation between the gases values in ABG and saliva. Data were analyzed using...
Anesthesiology and Pain Medicine, Apr 30, 2022
Background: Despite all of the benefits provided by laparoscopic cholecystectomy, such as rapid r... more Background: Despite all of the benefits provided by laparoscopic cholecystectomy, such as rapid recovery and shorter hospital stay for patients, the incidence of postoperative nausea and vomiting (PONV) and postoperative pain (POP) still remains high. Objectives: This study was designed to compare the effects of intraperitoneal (IP) and intravenous (IV) dexamethasone on the reduction of PONV and POP. Methods: This prospective, randomized, double-blind clinical trial was conducted on a study population of 86 adult patients who were scheduled for laparoscopic cholecystectomy with the American Society of Anesthesiologists class I-II. The patients were randomized into three groups, namely IP dexamethasone (n = 29), IV dexamethasone (n = 29), and control (n = 28) groups. The patients were followed for clinical outcomes, including PONV, POP, and consumption of antiemetics, and their hemodynamic status during the first 24 hours after the surgery. Results: In the first 24 hours after the operation, no significant differences were observed in nausea (P = 0.41) and vomiting (P = 0.38) between the IP and IV dexamethasone groups. However, there was a lower severity of nausea in the IP group (P = 0.001). Additionally, the visual analog scale score representing POP was significantly reduced in the IP group (P = 0.02). No significant differences in the hemodynamic status were observed after the operation between all the three groups. Conclusions: The administration of 8 mg IP dexamethasone was associated with significantly reduced pain and severity of nausea, but not PONV, after laparoscopic cholecystectomy.
Tehran University Medical Journal TUMS Publications, Aug 10, 2021
<jats:p>Background: One of the complications of ECT treatment is headache. There is a need ... more <jats:p>Background: One of the complications of ECT treatment is headache. There is a need to use sedation during ECT. As a result, midazolam has been used to address a safe and effective strategy in this regard.
 Methods: This study is a double-blind clinical trial that has been performed in three groups: group A, which receives midazolam based on the usual regimen, group B, which receives midazolam after shock, and group C, which is the control group. Patients were asked about headache, nausea, and muscle aches during the recovery time, seizure duration and after becoming fully conscious. Data were analyzed in the PASW version18 software using analysis of variance and repeated measurement tests, ANOVA, independed t and χ2 tests.
 Results: Analysis showed that the frequency of muscle pain after full consciousness in group C was significantly higher than group B, with group B being higher than group A. χ2 test showed that the frequency of headache, cough and nausea in group C was significantly higher than the two groups A and B.
 Conclusion: The result of this research showed that midazolam prodrug plays an effective role in preventing post-ECT complications in children. The effect of midazolam before and after ECT on headache, muscle pain and nausea was investigated and compared with the control group. Also, due to its anterograde amnesia, midazolam can reduce the patient's stress in the next visits, and this issue is even more important when the patient is a child.</jats:p>
JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), Mar 1, 2005
Background: Perioperative pain is prevalent and poorly treated. Apart from that it makes the reco... more Background: Perioperative pain is prevalent and poorly treated. Apart from that it makes the recovery from surgery unpleasent, pain often remains as a residual side effect of surgery, even though the tissue healing is complete. An essential observation is that tissue injury and the resulting nociceptor barrage initiates a cascade of events that can indelibly alter pain perception. Preemptive analgesia is the concept of initiating analgesic therapy before the onset of the noxious stimulus so as to prevent the nociceptor barrage and its ...
Anesthesiology and Pain Medicine, 2021
Objectives: The purpose of this study is a comparison of Valsalva, lidocaine, and Valsalva with a... more Objectives: The purpose of this study is a comparison of Valsalva, lidocaine, and Valsalva with administration of lidocaine to reduce the pain associated with administration of etomidate. Methods: The present study is a clinical trial study. The number of samples in each group was 30 and a total of 90 people were selected. This study was a clinical trial and the subjects were randomly divided into three groups: Group 1: Valsalva, 2: Lidocaine, 3: Valsalva and Lidocaine. Pain due to etomidate was rated on a VAS from 1 (painless) to 3 (worst imaginable pain) and their information was recorded. The collected information was entered into SPSS 22 and analyzed with appropriate statistical tests. Results: A total of 90 subjects participated in the present study and were divided into 3 groups: Valsalva, lidocaine, and Valsalva with lidocaine. No significant difference was observed between demographic variables in the study groups. There was a significant relationship between severity of pai...