suchandra chatterjee - Academia.edu (original) (raw)
Papers by suchandra chatterjee
barc.ernet.in
Minimally processed convenience foods like ready to cook (RTC) and ready to eat (RTE) products ha... more Minimally processed convenience foods like ready to cook (RTC) and ready to eat (RTE) products have gained prominence in recent years due to busy lifestyle of consumers resulting in demand for foods that can be readily cooked and served. Hurdle technology ...
The feasibility of using gamma irradiation to reduce microbial load and enhance shelf life of sal... more The feasibility of using gamma irradiation to reduce microbial load and enhance shelf life of salacia reticulata was investigated. The irradiated and non-irradiated products were stored at room temperature (25-32 °C and 50-85% R.H) for 2 years. Acceptability of the irradiated product was assessed based on sensory, microbial and antioxidant status (estimating reducing power, lipid peroxidation inhibitory activity and scavenging activities of DPPH, NO and H2O2 radicals). A dose of 10 kGy was sufficient to maintain microbial quality within acceptable limit up to 2 years of storage. No significant differences in sensory properties and antioxidant activities were observed between the non-irradiated and irradiated samples.
International Forestry Review, 2008
India has been identified as a source country for the illegal international trade in endangered p... more India has been identified as a source country for the illegal international trade in endangered pangolins, "scaly mammalian anteaters", widely considered as the "world's most trafficked mammal". In this study, we investigated the involvement of hunters belonging principally to three locally prominent tribes (Biate, Dimasa and Karbi) in Assam State, Northeast India. Based on the results of interviews with 141 individuals, we conclude that all three tribal groups engaged in pangolin hunting between 2011 and 2016. Although pangolin meat is used locally, we found that hunters largely targeted pangolins for their scales and that substantial commercial gain via urban middlemen has now supplanted low-level traditional use as the primary driver for this activity. On average, each hunter captured one pangolin per year with the potential to earn 9,000 INR (135 USD) for a single animal (equating to approximately four months average income). The majority of hunters (89%) stated that pangolins were less abundant than they were five years ago, which suggests off-take is unsustainable. All hunters interviewed appeared to hunt pangolins occasionally, regardless of tribe, demography or income, which suggests that any mitigation strategy should focus on rural hunters. Whilst interventions to reduce poverty are no doubt required, we argue that such interventions alone are unlikely to be effective in reducing pangolin hunting. Rather, there is a need for coordinated packages of mutually reinforcing interventions to address this pangolin hunting in a more comprehensive manner. In particular, implementing a demand reduction strategy targeting urban consumers is urgently required.
Journal of Agricultural and Food Chemistry, 2008
Cashew nut samples were irradiated at γ-radiation doses of 0.25, 0.5, 0.75, and 1 kGy, the permis... more Cashew nut samples were irradiated at γ-radiation doses of 0.25, 0.5, 0.75, and 1 kGy, the permissible dose range for insect disinfestation of food commodities. A weak and short-lived triplet (g) 2.004 and hfcc) 30 G) along with an anisotropic signal (g ⊥) 2.0069 and g |) 2.000) were produced immediately after irradiation. These signals were assigned to that of cellulose and CO 2 radicals. However, the irradiated samples showed a dose-dependent increase of the central line (g) 2.0045 (0.0002). The nature of the free radicals formed during conventional processing such as thermal treatment was investigated and showed an increase in intensity of the central line (g) 2.0045) similar to that of irradiation. Characteristics of the free radicals were studied by their relaxation and thermal behaviors. The present work explores the possibility to identify irradiated cashew nuts from nonirradiated ones by the thermal behaviors of the radicals beyond the period, when the characteristic electron paramagnetic resonance spectral lines of the cellulose free radicals have essentially disappeared. In addition, this study for the first time reports that relaxation behavior of the radicals could be a useful tool to distinguish between roasted and irradiated cashew nuts.
Food Chemistry, 2007
... Preparation of plasmid DNA 2.9.1. Testing of radio sensitivity of plasmid DNA 2.10. Data anal... more ... Preparation of plasmid DNA 2.9.1. Testing of radio sensitivity of plasmid DNA 2.10. Data analysis 3. Results and discussion 3.1. DPPH radical scavenging activity 3.2. ... 2.10. Data analysis. Data collected are an average of three independent determinations. ...
Food Chemistry, 2009
... subjected to steam distillation using simultaneous distillationextraction technique accordin... more ... subjected to steam distillation using simultaneous distillationextraction technique according to the procedure described earlier (Variyar, Ahmad, Bhat, Niyas, & Sharma ... The operating conditions were: column temperature programmed from 60 to 200 °C at the rate of 4 °C min − ...
MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis ... more MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis (3ethylbenzothiazoline6sulfonate) ABTS, 2, 4, 62thiobarbituric acid (TBA), 1, 1, 3, 3tetramethoxypropane (TMP), vitexin, isovitexin standards (HPLC grade) were purchased from Sigma Chemical Co., U.S.A. HPLC grade acetonitrile, methanol and trifluoroacetic acid (TFA) and Hydrogen peroxide were purchased from Merck (Germany). Dulbecco's modified Eagle's medium (DMEM), foetal bovine serum (FBS), penicillin and streptomycin were purchased from GIBCO life technologies. All other chemicals used in this study were of analytical grade and were procured from local suppliers. Biologicals Male or female Wistar rats weighing 250 ± 20 g were used to isolate liver mitochondria and were locally purchased from Institute of Vetenary and Biological Sciences, Pune. They were housed in polypropylene cages
Food Chemistry, 2014
Effect of radiation processing (0.5-2 kGy) and storage on the volatile oil constituents and gluco... more Effect of radiation processing (0.5-2 kGy) and storage on the volatile oil constituents and glucosinolate profile of cabbage was investigated. Among the volatile oil constituents, an enhancement in trans-hex-2-enal was noted on irradiation that was attributed to the increased liberation of precursor linolenic acid mainly from monogalactosyl diacyl glycerol (MGDG). Irradiation also enhanced sinigrin, the major glucosinolate of cabbage that accounted for the enhanced allyl isothiocyanate (AITC) in the volatile oils of the irradiated vegetable. During storage the content of trans-hex-2-enal increased immediately after irradiation and then returned to the basal value within 24h while the content of sinigrin and AITC increased post irradiation and thereafter remained constant during storage. Our findings on the enhancement in potentially important health promoting compounds such as sinigrin and AITC demonstrates that besides extending shelf life and safety, radiation processing can have an additional advantage in improving the nutritional quality of cabbage.
Journal of Agriculture and Food Research
Current Physical Chemistry
Aims: The aim is to search for newer and better antioxidants through kinetic spectroscopic studie... more Aims: The aim is to search for newer and better antioxidants through kinetic spectroscopic studies in combination with product analysis and computation. Background: Antioxidant effect of caffeic acid, its derivative, and analogues have been well reported. The antioxidative efficiencies are related to their molecular structure, and two reaction pathways are well accepted, H-atom transfer (HAT) or single electron transfer. 1-hydroxy ethyl radical (1-HER) being an ethanol-derived free radical might be causing the onset of liver injury detected after alcohol administration. 1-HER has also been reported to react with fatty acids and endogenous antioxidants such as glutathione, ascorbic acid, and alpha-tocopherol Objective: The present study is an attempt to understand the reaction mechanism of 1-HER with caffeic acid, its derivative, and analogues in detail. Method: Pulse radiolysis with kinetic absorption spectroscopy has been employed to follow the reaction pathway and identify the int...
Waste and Biomass Valorization
Substantial waste is generated from fish processing industries causing pollution and health hazar... more Substantial waste is generated from fish processing industries causing pollution and health hazard. Hence, synthesizing biodegradable film from myofibrillar protein dispersion of fish waste was attempted which may serve as “Wealth from Waste”- an eco-friendly initiative. Film dispersions were gamma-irradiated at a dose of 10 (D10) and 25 kGy (D25) before casting and their physical properties were tested where film from non-irradiated dispersion served as control. The results showed control (D0) had minimum tensile strength and maximum elongation at break whereas D10 and D25 had comparable values. Opacity with yellowness increased proportionally with dose. Water solubility was found to be similar for D0 and D25 whereas D10 had the lowest value. Water vapour permeability was highest in D25 as compared to D0 and D10 and free sulfhydryl content was lowest in D10 as compared to D0 and D25. Corroborating all data, D10 was found to be better as compared to D0 and D25.
RSC Advances
The noncovalent host-guest interaction of sanguinarine (SGR) with a nontoxic, water soluble sulfo... more The noncovalent host-guest interaction of sanguinarine (SGR) with a nontoxic, water soluble sulfobutylether-beta-cyclodextrin macrocyclic host modulates the photophysical properties, improves the photostability and antibacterial activity of SGR.
Chemical Communications
The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentratio... more The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentration (MIC) of sanguinarine (SGR) drug have been demonstrated through the uptake of SGR by p-sulfonatocalix[6]arene-functionalized silver nanoparticles. The...
Current genetics, Jan 25, 2018
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyses the sixth step of glycolysis, and is a... more Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyses the sixth step of glycolysis, and is also known to perform other (moonlighting) activities in animal cells. We have earlier identified an additional GAPDH gene in Trichoderma virens genome. This gene is consistently associated with the vir cluster responsible for biosynthesis of a range of volatile sesquiterpenes in Trichoderma virens. This gene is also associated with an orthologous gene cluster in Aspergillus spp. Both glycolytic GAPDH and the vir cluster-associated GAPDH show more than 80% similarity with essentially conserved NAD cofactor- and substrate-binding sites. However, a conserved indel is consistently present only in GAPDH associated with the vir cluster, both in T. virens and Aspergillus spp. Using gene knockout, we demonstrate here that the vir cluster-associated GAPDH is involved in biosynthesis of volatile sesquiterpenes in T. virens. We thus, for the first time, elucidate the non-glycolytic role of a GAPDH ...
The Natural Products Journal
Free Radicals and Antioxidants, 2016
MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis ... more MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis (3ethylbenzothiazoline6sulfonate) ABTS, 2, 4, 62thiobarbituric acid (TBA), 1, 1, 3, 3tetramethoxypropane (TMP), vitexin, isovitexin standards (HPLC grade) were purchased from Sigma Chemical Co., U.S.A. HPLC grade acetonitrile, methanol and trifluoroacetic acid (TFA) and Hydrogen peroxide were purchased from Merck (Germany). Dulbecco's modified Eagle's medium (DMEM), foetal bovine serum (FBS), penicillin and streptomycin were purchased from GIBCO life technologies. All other chemicals used in this study were of analytical grade and were procured from local suppliers. Biologicals Male or female Wistar rats weighing 250 ± 20 g were used to isolate liver mitochondria and were locally purchased from Institute of Vetenary and Biological Sciences, Pune. They were housed in polypropylene cages
Journal of Food Science, 2012
Frontiers in Chemistry
Porphyrins, especially the 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin (TMPyP), are well-acc... more Porphyrins, especially the 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin (TMPyP), are well-accepted as photosensitizers due to strong absorption from visible to near-infrared region, good singlet oxygen quantum yields as well as chemical versatility, all of which can be further modulated through planned supramolecular strategies. In this study, we report the construction of supramolecular nanorods of TMPyP dye/drug with captisol [sulfobutylether-β-cyclodextrin (SBE 7 βCD)] macrocycle through host-guest interaction. The availability of four cationic N-methylpyridyl groups favors multiple binding interaction with the captisol host, building an extended supramolecular assembly of captisol and TMPyP. In addition to the spectroscopic characterizations for the assembly formation, the same has been pictured in SEM and FM images as nanorods of ∼10 µm in length or more. Complexation of TMPyP has brought out beneficial features over the uncomplexed TMPyP dye; enhanced singlet oxygen yield, improved photostability, and better photosensitizing effect, all supportive of efficient photodynamic therapy activity. The Captisol:TMPyP complex displayed enhanced antibacterial activity toward E. coli under white light irradiation as compared to TMPyP alone. Cell viability studies performed in lung carcinoma A549 cells with light irradiation documented increased cytotoxicity of the complex toward the cancer cells whereas reduced dark toxicity is observed toward normal CHO cells. All these synergistic effects of supramolecular nanorods of Captisol-TMPyP complex make the system an effective photosensitizer and a superior antibacterial and antitumor agent.
barc.ernet.in
Minimally processed convenience foods like ready to cook (RTC) and ready to eat (RTE) products ha... more Minimally processed convenience foods like ready to cook (RTC) and ready to eat (RTE) products have gained prominence in recent years due to busy lifestyle of consumers resulting in demand for foods that can be readily cooked and served. Hurdle technology ...
The feasibility of using gamma irradiation to reduce microbial load and enhance shelf life of sal... more The feasibility of using gamma irradiation to reduce microbial load and enhance shelf life of salacia reticulata was investigated. The irradiated and non-irradiated products were stored at room temperature (25-32 °C and 50-85% R.H) for 2 years. Acceptability of the irradiated product was assessed based on sensory, microbial and antioxidant status (estimating reducing power, lipid peroxidation inhibitory activity and scavenging activities of DPPH, NO and H2O2 radicals). A dose of 10 kGy was sufficient to maintain microbial quality within acceptable limit up to 2 years of storage. No significant differences in sensory properties and antioxidant activities were observed between the non-irradiated and irradiated samples.
International Forestry Review, 2008
India has been identified as a source country for the illegal international trade in endangered p... more India has been identified as a source country for the illegal international trade in endangered pangolins, "scaly mammalian anteaters", widely considered as the "world's most trafficked mammal". In this study, we investigated the involvement of hunters belonging principally to three locally prominent tribes (Biate, Dimasa and Karbi) in Assam State, Northeast India. Based on the results of interviews with 141 individuals, we conclude that all three tribal groups engaged in pangolin hunting between 2011 and 2016. Although pangolin meat is used locally, we found that hunters largely targeted pangolins for their scales and that substantial commercial gain via urban middlemen has now supplanted low-level traditional use as the primary driver for this activity. On average, each hunter captured one pangolin per year with the potential to earn 9,000 INR (135 USD) for a single animal (equating to approximately four months average income). The majority of hunters (89%) stated that pangolins were less abundant than they were five years ago, which suggests off-take is unsustainable. All hunters interviewed appeared to hunt pangolins occasionally, regardless of tribe, demography or income, which suggests that any mitigation strategy should focus on rural hunters. Whilst interventions to reduce poverty are no doubt required, we argue that such interventions alone are unlikely to be effective in reducing pangolin hunting. Rather, there is a need for coordinated packages of mutually reinforcing interventions to address this pangolin hunting in a more comprehensive manner. In particular, implementing a demand reduction strategy targeting urban consumers is urgently required.
Journal of Agricultural and Food Chemistry, 2008
Cashew nut samples were irradiated at γ-radiation doses of 0.25, 0.5, 0.75, and 1 kGy, the permis... more Cashew nut samples were irradiated at γ-radiation doses of 0.25, 0.5, 0.75, and 1 kGy, the permissible dose range for insect disinfestation of food commodities. A weak and short-lived triplet (g) 2.004 and hfcc) 30 G) along with an anisotropic signal (g ⊥) 2.0069 and g |) 2.000) were produced immediately after irradiation. These signals were assigned to that of cellulose and CO 2 radicals. However, the irradiated samples showed a dose-dependent increase of the central line (g) 2.0045 (0.0002). The nature of the free radicals formed during conventional processing such as thermal treatment was investigated and showed an increase in intensity of the central line (g) 2.0045) similar to that of irradiation. Characteristics of the free radicals were studied by their relaxation and thermal behaviors. The present work explores the possibility to identify irradiated cashew nuts from nonirradiated ones by the thermal behaviors of the radicals beyond the period, when the characteristic electron paramagnetic resonance spectral lines of the cellulose free radicals have essentially disappeared. In addition, this study for the first time reports that relaxation behavior of the radicals could be a useful tool to distinguish between roasted and irradiated cashew nuts.
Food Chemistry, 2007
... Preparation of plasmid DNA 2.9.1. Testing of radio sensitivity of plasmid DNA 2.10. Data anal... more ... Preparation of plasmid DNA 2.9.1. Testing of radio sensitivity of plasmid DNA 2.10. Data analysis 3. Results and discussion 3.1. DPPH radical scavenging activity 3.2. ... 2.10. Data analysis. Data collected are an average of three independent determinations. ...
Food Chemistry, 2009
... subjected to steam distillation using simultaneous distillationextraction technique accordin... more ... subjected to steam distillation using simultaneous distillationextraction technique according to the procedure described earlier (Variyar, Ahmad, Bhat, Niyas, & Sharma ... The operating conditions were: column temperature programmed from 60 to 200 °C at the rate of 4 °C min − ...
MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis ... more MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis (3ethylbenzothiazoline6sulfonate) ABTS, 2, 4, 62thiobarbituric acid (TBA), 1, 1, 3, 3tetramethoxypropane (TMP), vitexin, isovitexin standards (HPLC grade) were purchased from Sigma Chemical Co., U.S.A. HPLC grade acetonitrile, methanol and trifluoroacetic acid (TFA) and Hydrogen peroxide were purchased from Merck (Germany). Dulbecco's modified Eagle's medium (DMEM), foetal bovine serum (FBS), penicillin and streptomycin were purchased from GIBCO life technologies. All other chemicals used in this study were of analytical grade and were procured from local suppliers. Biologicals Male or female Wistar rats weighing 250 ± 20 g were used to isolate liver mitochondria and were locally purchased from Institute of Vetenary and Biological Sciences, Pune. They were housed in polypropylene cages
Food Chemistry, 2014
Effect of radiation processing (0.5-2 kGy) and storage on the volatile oil constituents and gluco... more Effect of radiation processing (0.5-2 kGy) and storage on the volatile oil constituents and glucosinolate profile of cabbage was investigated. Among the volatile oil constituents, an enhancement in trans-hex-2-enal was noted on irradiation that was attributed to the increased liberation of precursor linolenic acid mainly from monogalactosyl diacyl glycerol (MGDG). Irradiation also enhanced sinigrin, the major glucosinolate of cabbage that accounted for the enhanced allyl isothiocyanate (AITC) in the volatile oils of the irradiated vegetable. During storage the content of trans-hex-2-enal increased immediately after irradiation and then returned to the basal value within 24h while the content of sinigrin and AITC increased post irradiation and thereafter remained constant during storage. Our findings on the enhancement in potentially important health promoting compounds such as sinigrin and AITC demonstrates that besides extending shelf life and safety, radiation processing can have an additional advantage in improving the nutritional quality of cabbage.
Journal of Agriculture and Food Research
Current Physical Chemistry
Aims: The aim is to search for newer and better antioxidants through kinetic spectroscopic studie... more Aims: The aim is to search for newer and better antioxidants through kinetic spectroscopic studies in combination with product analysis and computation. Background: Antioxidant effect of caffeic acid, its derivative, and analogues have been well reported. The antioxidative efficiencies are related to their molecular structure, and two reaction pathways are well accepted, H-atom transfer (HAT) or single electron transfer. 1-hydroxy ethyl radical (1-HER) being an ethanol-derived free radical might be causing the onset of liver injury detected after alcohol administration. 1-HER has also been reported to react with fatty acids and endogenous antioxidants such as glutathione, ascorbic acid, and alpha-tocopherol Objective: The present study is an attempt to understand the reaction mechanism of 1-HER with caffeic acid, its derivative, and analogues in detail. Method: Pulse radiolysis with kinetic absorption spectroscopy has been employed to follow the reaction pathway and identify the int...
Waste and Biomass Valorization
Substantial waste is generated from fish processing industries causing pollution and health hazar... more Substantial waste is generated from fish processing industries causing pollution and health hazard. Hence, synthesizing biodegradable film from myofibrillar protein dispersion of fish waste was attempted which may serve as “Wealth from Waste”- an eco-friendly initiative. Film dispersions were gamma-irradiated at a dose of 10 (D10) and 25 kGy (D25) before casting and their physical properties were tested where film from non-irradiated dispersion served as control. The results showed control (D0) had minimum tensile strength and maximum elongation at break whereas D10 and D25 had comparable values. Opacity with yellowness increased proportionally with dose. Water solubility was found to be similar for D0 and D25 whereas D10 had the lowest value. Water vapour permeability was highest in D25 as compared to D0 and D10 and free sulfhydryl content was lowest in D10 as compared to D0 and D25. Corroborating all data, D10 was found to be better as compared to D0 and D25.
RSC Advances
The noncovalent host-guest interaction of sanguinarine (SGR) with a nontoxic, water soluble sulfo... more The noncovalent host-guest interaction of sanguinarine (SGR) with a nontoxic, water soluble sulfobutylether-beta-cyclodextrin macrocyclic host modulates the photophysical properties, improves the photostability and antibacterial activity of SGR.
Chemical Communications
The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentratio... more The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentration (MIC) of sanguinarine (SGR) drug have been demonstrated through the uptake of SGR by p-sulfonatocalix[6]arene-functionalized silver nanoparticles. The...
Current genetics, Jan 25, 2018
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyses the sixth step of glycolysis, and is a... more Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyses the sixth step of glycolysis, and is also known to perform other (moonlighting) activities in animal cells. We have earlier identified an additional GAPDH gene in Trichoderma virens genome. This gene is consistently associated with the vir cluster responsible for biosynthesis of a range of volatile sesquiterpenes in Trichoderma virens. This gene is also associated with an orthologous gene cluster in Aspergillus spp. Both glycolytic GAPDH and the vir cluster-associated GAPDH show more than 80% similarity with essentially conserved NAD cofactor- and substrate-binding sites. However, a conserved indel is consistently present only in GAPDH associated with the vir cluster, both in T. virens and Aspergillus spp. Using gene knockout, we demonstrate here that the vir cluster-associated GAPDH is involved in biosynthesis of volatile sesquiterpenes in T. virens. We thus, for the first time, elucidate the non-glycolytic role of a GAPDH ...
The Natural Products Journal
Free Radicals and Antioxidants, 2016
MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis ... more MATERIAL AND METHODS Chemicals 2, 2Diphenyl 1picrylhydrazyl (DPPH), LAscorbic acid, 2, 2azinobis (3ethylbenzothiazoline6sulfonate) ABTS, 2, 4, 62thiobarbituric acid (TBA), 1, 1, 3, 3tetramethoxypropane (TMP), vitexin, isovitexin standards (HPLC grade) were purchased from Sigma Chemical Co., U.S.A. HPLC grade acetonitrile, methanol and trifluoroacetic acid (TFA) and Hydrogen peroxide were purchased from Merck (Germany). Dulbecco's modified Eagle's medium (DMEM), foetal bovine serum (FBS), penicillin and streptomycin were purchased from GIBCO life technologies. All other chemicals used in this study were of analytical grade and were procured from local suppliers. Biologicals Male or female Wistar rats weighing 250 ± 20 g were used to isolate liver mitochondria and were locally purchased from Institute of Vetenary and Biological Sciences, Pune. They were housed in polypropylene cages
Journal of Food Science, 2012
Frontiers in Chemistry
Porphyrins, especially the 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin (TMPyP), are well-acc... more Porphyrins, especially the 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin (TMPyP), are well-accepted as photosensitizers due to strong absorption from visible to near-infrared region, good singlet oxygen quantum yields as well as chemical versatility, all of which can be further modulated through planned supramolecular strategies. In this study, we report the construction of supramolecular nanorods of TMPyP dye/drug with captisol [sulfobutylether-β-cyclodextrin (SBE 7 βCD)] macrocycle through host-guest interaction. The availability of four cationic N-methylpyridyl groups favors multiple binding interaction with the captisol host, building an extended supramolecular assembly of captisol and TMPyP. In addition to the spectroscopic characterizations for the assembly formation, the same has been pictured in SEM and FM images as nanorods of ∼10 µm in length or more. Complexation of TMPyP has brought out beneficial features over the uncomplexed TMPyP dye; enhanced singlet oxygen yield, improved photostability, and better photosensitizing effect, all supportive of efficient photodynamic therapy activity. The Captisol:TMPyP complex displayed enhanced antibacterial activity toward E. coli under white light irradiation as compared to TMPyP alone. Cell viability studies performed in lung carcinoma A549 cells with light irradiation documented increased cytotoxicity of the complex toward the cancer cells whereas reduced dark toxicity is observed toward normal CHO cells. All these synergistic effects of supramolecular nanorods of Captisol-TMPyP complex make the system an effective photosensitizer and a superior antibacterial and antitumor agent.