denise manieu - Academia.edu (original) (raw)

Papers by denise manieu

Revista chilena de infectología, 2002

Histoplasma capsulatum is a dysmorphic fungus that dwells on earth in specific geographic locatio... more Histoplasma capsulatum is a dysmorphic fungus that dwells on earth in specific geographic locations. Its presence is favored by the droppings of bird and bats. The human infection is caused by the inhalation of a high quantity of spores. We describe the clinical course of a forty three year old immunocompetent male , geologist, who acquired the infection while visiting underground mines in Central America and Peru. Ninety (90%) percent of the Histoplasma spp infection are asymptomatic. The rest of the cases are manifested by pulmonary or non focalized infection. Its diagnosis is based on cutaneous reaction tests, the detection of antigens in blood or urine and also by direct visual identification of the agent in clinical samples or culture. These patients must be treated with itraconazole or amphotericin-B in accordance to its clinical seriousness.

Rev Chil Salud Publica, 2003

Resumo: La luxación congénita de cadera es la malformación ortopédica más frecuente en el hombre.... more Resumo: La luxación congénita de cadera es la malformación ortopédica más frecuente en el hombre. En Chile estudios muestran que la LCC tiene una incidencia de 7 por 10.000 nacidos vivos, y la displasia alrededor del 4 por ciento en lactantes de 3 meses de edad. ...

Arch Chil Oftalmol, 2010

... Autor: Manieu M., Denise; López G., Juan P; Villaseca D., Eduardo; Roizen B., Alejandra; Gonz... more ... Autor: Manieu M., Denise; López G., Juan P; Villaseca D., Eduardo; Roizen B., Alejandra; González N., Militza. ... El tipo, frecuencia y promedio de ángulo de desviación preoperatorio fueron respectivamente: XT, n=14 (48 por ciento), -29; XHT, n=7 (24 por ciento), -29, I/D=20; ET ...

Revista chilena de pediatría, 1988

Revista chilena de enfermedades respiratorias, 2003

RESUMEN La mujer embarazada presenta cambios fisiológicos respiratorios como son la hiperventilac... more RESUMEN La mujer embarazada presenta cambios fisiológicos respiratorios como son la hiperventilación y disnea. Algunas complicaciones pulmonares pueden pasar inadvertidas si los signos y sintomas de enfermedad son sutiles y se confunden con los cambios ...

Revista chilena de pediatría, 1986

Revista chilena de infectología, 2002

... PULMONARY HISTOPLASMOSIS. HERNÁN CABELLO A. 3 , DENISE MANIEU M. 2 , L. MIGUEL NORIEGA R. 3 ,... more ... PULMONARY HISTOPLASMOSIS. HERNÁN CABELLO A. 3 , DENISE MANIEU M. 2 , L. MIGUEL NORIEGA R. 3 , MANUEL MENESES C. 4 , MARCIAL PERALTA M. 5 y CONSTANZA LARRAGUIBEL H. 2. ... 4 Servicio de Anatomía Patológica Hospital Del Salvador, Santiago. ...

Revista chilena de infectología, 2011

Intraocular invasion by Toxocara canis is one of the most commonly recognized etiologies of uveit... more Intraocular invasion by Toxocara canis is one of the most commonly recognized etiologies of uveitis and blindness in children. In order to estimate the prevalence of ocular lesions caused by toxocariasis in a pediatric referral hospital, we conducted a retrospective analysis of clinical charts of all children seropositive to Toxocara canis, who also had an eye exam between the years 2005 and 2009 at the Calvo Mackenna Children´s Hospital in Santiago, Chile. We identifi ed 175 children [mean age 6 years (range 0.66-15)] seropositive to Toxocara canis, who had dilated eye exam. Only one child [(0.57%); 95% CI,-0.55-1.69] had ophthalmoscopic fi ndings compatible with Toxocara canis infection. The patient also suffered from decreased vision of the affected eye. The information gained from this study may be of useful for the implementation of algorithms for the ophthalmological examination of children seropositive to Toxocara canis in public hospitals in Chile.

Revista chilena de pediatría, 2008

Retinoblastoma in children, experience at a pediatric hospital Methods: Retrospective analysis of... more Retinoblastoma in children, experience at a pediatric hospital Methods: Retrospective analysis of clinical charts of 41 children (59 eyes) diagnosed with retinoblastoma and treated by a multidisciplinary team at Hospital Luis Calvo Mackenna in Santiago-Chile, between 1999 and 2007. The information included gender, laterality, diagnosis age, presenting signs, tumor spread, treatment modality and survival rate. Results: A total of 23 cases (56%) were unilateral and 18 cases (44%) were bilateral. The mean age at diagnosis was 21.6 months (range 2-84) and 27 children (65.9%) were male. The most common presenting signs were leucokoria (51.2%), strabismus (24.4%) and proptosis (4.9%). Enucleation was performed in 48 eyes (81.3%), being the only required treatment in 17 children (41.5%). The remaining 24 patients received systemic and/or local therapy with chemotherapy, focal therapy and external beam radiation. 5 children died during the follow-up study period, due to extraocular extension to the orbit, central nervous system and bone marrow. Conclusion: In spite of high enucleation rate as initial therapy for retinoblastoma, the survival rate with this current treatment protocol is similar to those from developed countries.

Revista chilena de infectología, 2002

Histoplasma capsulatum is a dysmorphic fungus that dwells on earth in specific geographic locatio... more Histoplasma capsulatum is a dysmorphic fungus that dwells on earth in specific geographic locations. Its presence is favored by the droppings of bird and bats. The human infection is caused by the inhalation of a high quantity of spores. We describe the clinical course of a forty three year old immunocompetent male , geologist, who acquired the infection while visiting underground mines in Central America and Peru. Ninety (90%) percent of the Histoplasma spp infection are asymptomatic. The rest of the cases are manifested by pulmonary or non focalized infection. Its diagnosis is based on cutaneous reaction tests, the detection of antigens in blood or urine and also by direct visual identification of the agent in clinical samples or culture. These patients must be treated with itraconazole or amphotericin-B in accordance to its clinical seriousness.

Rev Chil Salud Publica, 2003

Resumo: La luxación congénita de cadera es la malformación ortopédica más frecuente en el hombre.... more Resumo: La luxación congénita de cadera es la malformación ortopédica más frecuente en el hombre. En Chile estudios muestran que la LCC tiene una incidencia de 7 por 10.000 nacidos vivos, y la displasia alrededor del 4 por ciento en lactantes de 3 meses de edad. ...

Arch Chil Oftalmol, 2010

... Autor: Manieu M., Denise; López G., Juan P; Villaseca D., Eduardo; Roizen B., Alejandra; Gonz... more ... Autor: Manieu M., Denise; López G., Juan P; Villaseca D., Eduardo; Roizen B., Alejandra; González N., Militza. ... El tipo, frecuencia y promedio de ángulo de desviación preoperatorio fueron respectivamente: XT, n=14 (48 por ciento), -29; XHT, n=7 (24 por ciento), -29, I/D=20; ET ...

Revista chilena de pediatría, 1988

Revista chilena de enfermedades respiratorias, 2003

RESUMEN La mujer embarazada presenta cambios fisiológicos respiratorios como son la hiperventilac... more RESUMEN La mujer embarazada presenta cambios fisiológicos respiratorios como son la hiperventilación y disnea. Algunas complicaciones pulmonares pueden pasar inadvertidas si los signos y sintomas de enfermedad son sutiles y se confunden con los cambios ...

Revista chilena de pediatría, 1986

Revista chilena de infectología, 2002

... PULMONARY HISTOPLASMOSIS. HERNÁN CABELLO A. 3 , DENISE MANIEU M. 2 , L. MIGUEL NORIEGA R. 3 ,... more ... PULMONARY HISTOPLASMOSIS. HERNÁN CABELLO A. 3 , DENISE MANIEU M. 2 , L. MIGUEL NORIEGA R. 3 , MANUEL MENESES C. 4 , MARCIAL PERALTA M. 5 y CONSTANZA LARRAGUIBEL H. 2. ... 4 Servicio de Anatomía Patológica Hospital Del Salvador, Santiago. ...

Revista chilena de infectología, 2011

Intraocular invasion by Toxocara canis is one of the most commonly recognized etiologies of uveit... more Intraocular invasion by Toxocara canis is one of the most commonly recognized etiologies of uveitis and blindness in children. In order to estimate the prevalence of ocular lesions caused by toxocariasis in a pediatric referral hospital, we conducted a retrospective analysis of clinical charts of all children seropositive to Toxocara canis, who also had an eye exam between the years 2005 and 2009 at the Calvo Mackenna Children´s Hospital in Santiago, Chile. We identifi ed 175 children [mean age 6 years (range 0.66-15)] seropositive to Toxocara canis, who had dilated eye exam. Only one child [(0.57%); 95% CI,-0.55-1.69] had ophthalmoscopic fi ndings compatible with Toxocara canis infection. The patient also suffered from decreased vision of the affected eye. The information gained from this study may be of useful for the implementation of algorithms for the ophthalmological examination of children seropositive to Toxocara canis in public hospitals in Chile.

Revista chilena de pediatría, 2008

Retinoblastoma in children, experience at a pediatric hospital Methods: Retrospective analysis of... more Retinoblastoma in children, experience at a pediatric hospital Methods: Retrospective analysis of clinical charts of 41 children (59 eyes) diagnosed with retinoblastoma and treated by a multidisciplinary team at Hospital Luis Calvo Mackenna in Santiago-Chile, between 1999 and 2007. The information included gender, laterality, diagnosis age, presenting signs, tumor spread, treatment modality and survival rate. Results: A total of 23 cases (56%) were unilateral and 18 cases (44%) were bilateral. The mean age at diagnosis was 21.6 months (range 2-84) and 27 children (65.9%) were male. The most common presenting signs were leucokoria (51.2%), strabismus (24.4%) and proptosis (4.9%). Enucleation was performed in 48 eyes (81.3%), being the only required treatment in 17 children (41.5%). The remaining 24 patients received systemic and/or local therapy with chemotherapy, focal therapy and external beam radiation. 5 children died during the follow-up study period, due to extraocular extension to the orbit, central nervous system and bone marrow. Conclusion: In spite of high enucleation rate as initial therapy for retinoblastoma, the survival rate with this current treatment protocol is similar to those from developed countries.