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Papers by nova dian lestari

Journal of Medical Science, Feb 16, 2023

Epilepsi adalah salah satu penyakit saraf yang paling umum terjadi, dapat mengenai setiap orang d... more Epilepsi adalah salah satu penyakit saraf yang paling umum terjadi, dapat mengenai setiap orang dari segala usia, ras, kelas sosial, dan lokasi geografis. Epilepsi disebabkan oleh pelepasan abnormal neuron pada otak yang ditandai dengan kejang. Data World Health Organization menunjukkan epilepsi menyerang hampir 50 juta orang di seluruh dunia. Tatalaksana epilepsi bertujuan mengontrol kejang dan meningkatkan kualitas hidup pasien. Namun, efek samping obat antiepilepsi (OAE) dapat secara signifikan mengganggu kualitas hidup. Penelitian ini bertujuan mengetahui hubungan antara lama pengobatan dan jenis OAE dengan efek samping obat pada pasien epilepsi, menggunakan desain studi analitik observasional dengan rancangan cross sectional. Sampel penelitian adalah pasien epilepsi di Poliklinik Neurologi RSUDZA berjumalh 42 orang yang memenuhi kriteria inklusi dan eksklusi. Pengambilan sampel dilakukan sejak Mei−September 2022 dengan teknik consecutive sampling dan pengisian kuesioner Liverpool Adverse Effect Profile (LAEP). Data ditabulasi dan dianalisis menggunakan analisis univariat untuk menyajikan frekuensi dan persentase, uji statistik Spearman's correlation digunakan untuk menguji hubungan antar variabel. Hasil penelitian menunjukkan pasien terdiri dari 17 pria (40,5%) dan 25 wanita (59,5%), rata-rata lama pengobatan yang telah dijalani adalah 52 bulan, dan seluruhnya mengalami efek samping OAE. Uji statistik Spearman's correlation memperlihatkan tidak terdapat hubungan antara lama pengobatan dan jenis OAE dengan efek samping obat pada pasien yang didiagnosa epilepsi di Poliklinik Neurologi RSUDZA.

International Journal of Research Publications

Epilepsy is a neurological disease which is able to affect people of all ages, races, social clas... more Epilepsy is a neurological disease which is able to affect people of all ages, races, social classes, as well as regions. It is caused by abnormal release of neurons in the brain characterized with seizures. In addition, epilepsy is often surrounded by prejudices and myths caused with a lack of society knowledge. It is associated with negative attitude and belief as a stigma toward epil epsy patient and therefore it could to influence psychological leading to decreasing the quality of life of the patients. The stud y aimed to assess the associations or correlations between demographic characteristics and knowledge of epilepsy in community members in Banda Aceh, Indonesia. A cross sectional with observational analytic design was conducted in nine districts from June 9 to July 14, 2021. The samples were those who fit with inclusion and exclusion criteria. Data collection was conducted using onli ne questionnaire employed a Google form platform. Spearman correlation, Mann-Whitney, and Kruskal-Wallis were used to analysis the data. A total of 312 respondents were included in final analysis. There were 43.9%, 48.7%, and 7.4% of the respondents had the level of knowledge what was classified as high, average and low, respectively. The results of this study indicated that the level of knowledge was influenced by gender, ethnicity, and occupation. In addition, there was a relationship between the level of education and the level of knowledge about epilepsy (p<0.01). There was no significant relationship between age and family history with knowledge about epilepsy in the community.

Jurnal Kedokteran Syiah Kuala

Pendahuluan: Praktik Interprofessional Collaboration (IPC) merupakan bentuk kerjasama antar tenag... more Pendahuluan: Praktik Interprofessional Collaboration (IPC) merupakan bentuk kerjasama antar tenaga kesehatan yang dilakukan secara kolaboratif untuk memastikan asuhan pasien berjalan secara optimal dan berkesinambungan. Profesional Pemberi Asuhan (PPA) dengan profesi dan keilmuan yang berbeda dituntut untuk bisa berkontribusi secara individu maupun dalam tim. Penelitian ini bertujuan untuk mengetahui gambaran praktik tim dan kerjasama tim antar PPA dalam implementasi Interprofessional Collaboration di RSUD Meuraxa Kota Banda Aceh.Metode: Penelitian ini merupakan penelitian kualitatif dengan pendekatan fenomenologi menggunakan metode in-depth interview dan Focus Group Discussion (FGD). Data direkam, ditranskripsi kemudian dianalisis menggunakan analisis tematik. Informan penelitian ini sebanyak 12 orang PPA yang terdiri dari Dokter Penanggung Jawab Pasien (DPJP), perawat, apoteker, dan dietisien. Penelitian dilakukan di RSUD Meuraxa Kota Banda Aceh selama bulan Juni-Juli tahun 2020.H...

Jurnal Administrasi Kesehatan Indonesia, 2021

Background: Interprofessional collaboration for patient care is integrated cooperation between he... more Background: Interprofessional collaboration for patient care is integrated cooperation between health workers in ensuring optimally consecutive patient care. Interprofessional decisions should be made in two ways between professional caregivers.Aims: This study aimed to analyze communication between professional caregivers in establishing interprofessional collaboration at Meuraxa District General Hospital in Banda Aceh.Method: This study was qualitative research and used a phenomenological approach. In-depth interviews and FGD were conducted with professional caregivers consisting of doctors in charge, nurses, pharmacists, and dietitians. All of the in-depth interviews and FGD were recorded and transcribed. Data obtained were analyzed thematically.Results: Communication between professional caregivers in establishing interprofessional collaboration at the hospital had not been well-performed. Overall, they had not optimally utilized integrated patient progress records as they focus...

Bali Medical Journal, 2021

Background: Depression is the most common comorbid in people with epilepsy (PWE). Detection of de... more Background: Depression is the most common comorbid in people with epilepsy (PWE). Detection of depression in PWE is not a routine examination at a neurology clinic because it takes a long time. The education of Acehnese people regarding epilepsy is still limited, leading to discrimination and stigma in society. It is not easy to carry out examinations, and the diagnosis is often overlooked. The objective of this study was to screen and to describe the characteristics of depression in PWE in Aceh. Method: This study was a descriptive observational study with the total respondents involved 41 PWEs. Detection of depression in PWE was conducted using the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E), a valid, reliable, shorter and more straightforward instrument test. The sample was determinate using the probability sampling method with a simple random sampling technique. Results: Our results found that 39% of respondents experienced depression, with the most NDDI-E scores ranged between 11-15, with a percentage of 41.5%. Out of total, 57.1% of the depression occurred in women and those who aged between 18-25 years old were more frequent to experience depression. Depression was more frequent among those who had no formal education (66.7%). Conclusion: Depression in PWE in Aceh tends to occur in women, those with no education and those who worked as labor or farmer.

Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia, 2020

HEMICHOREA/HEMIBALLISM ASSOCIATED WITH NONKETOTIC HYPERGLYCEMIC ON ACUTE ISCHEMIC STROKEABSTRACTH... more HEMICHOREA/HEMIBALLISM ASSOCIATED WITH NONKETOTIC HYPERGLYCEMIC ON ACUTE ISCHEMIC STROKEABSTRACTHemichorea/hemiballism (HCHB) associated with nonketotic hyperglycemia in acute ischemic stroke is a well-recognized syndrome characterized by the sudden occurrence of hemichorea or more severe expression like hemiballism. The hyperkinetic movements involve the face, arm, or leg. HCHB in acute ischemic stroke is a movement disorder that is rarely reported with hyperkinetic movement. This case report aimed to describe patient with HCHB associated with hyperglycemia as prior sign of stroke ischemic and propose a possible pathophysiology. We report three patients who had HCHB accompanied by hemiparesis, facial and hypoglossus nerve palsy. Laboratory results showed increased serum glucose levels and negative urine ketones. Imaging findings of head CT scan found an infarction in the basal ganglia. Patients are treated with antiplatelet and or anticoagulant therapy and correction of hyperglycem...

The government health financing system paid for hospital using the INA-CBG’s method. Stroke is th... more The government health financing system paid for hospital using the INA-CBG’s method. Stroke is the third most common cause of death after heart disease and cancer and stroke rank first as a cause of disability. Thus, the treatment of strokes due to disability and recurrent strokes requires a fairly high maintenance cost. Results: The total cost of ischemic stroke in 345 hospitalized cases with a total real cost was IDR 2.800.210.362 and a total cost of INA-CBG's of IDR 2.830.254.600.This has a significant difference, as well as severity levels and comorbidities. There is a difference between the real hospital rates and INA-CBG’s rates with a value of P = 0,000. The cost of caring for ischemic stroke patients the most cost was accommodation (22%). Conclusion: There is a difference between the real hospital costs and the INA-CBG’s rates for ischemic stroke patients at X Hospital, this is because there is still a negative difference associated with severity level, type of comorbid,...

Mutation of sodium voltage-gated channel alpha subunit 1 (SCN1A) gene is an important cause of ge... more Mutation of sodium voltage-gated channel alpha subunit 1 (SCN1A) gene is an important cause of genetic epilepsy and familial hemiplegic migraine. However, data related genetic variation of SCN1A in Indonesia is limited. This study aimed to identify SCN1A gene variation in idiopathic epilepsy and common migraine patients in Aceh province, Indonesia. A case-control study was conducted at Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia from March 1 st to August 30 th 2015. Gene variation analysis of exon 26 of SCN1A gene was conducted in 33 patients with idiopathic epilepsy, 33 with common migraine and 30 controls using polymerase chain reaction (PCR) and direct sequencing. DNA extraction was carried out at the School of Medicine, Syiah Kuala University, Banda Aceh, Indonesia. Amplification and sequencing of exon 26 of the SCN1A gene were conducted at the Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia and 1st BASE Pte. Ltd. Laboratory, Singapore, respectively. S...

Abstrak . Penyakit infeksi merupakan penyebab utama kematian di dunia terutama di daerah tropis, ... more Abstrak . Penyakit infeksi merupakan penyebab utama kematian di dunia terutama di daerah tropis, seperti Indonesia. Salah satu penyebab penyakit infeksi adalah bakteri Streptococcus pyogenes . Pengobatan penyakit akibat infeksi bakteri menggunakan antibiotik banyak menimbulkan resistensi dan efek samping, sehingga saat ini dikembangkan fitofarmaka yang memiliki potensi tinggi sebagai antibiotik. Salah satu tanaman yang secara empiris banyak digunakan untuk pengobatan adalah Rosella (Hibiscus sabdariffa L .) . Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antibakteri ekstrak etanol kelopak bunga Rosella terhadap Streptococcus pyogenes . Kelopak bunga Rosella diekstraksi dengan menggunakan pelarut etanol 96% dengan metode maserasi. Penelitian ini menggunakan Rancangan Acak Lengkap yang terdiri dari 6 kelompok perlakuan yaitu konsentrasi ekstrak 5%, 10%, 20% ,30%, kontrol positif (Ampisilin 10 µg) dan kontrol negatif (akuades steril), dengan 4 kali pengulangan uji aktivi...

Chronic low back pain (LBP) remains the immense problem faced by doctors nowadays. Lumbar facet j... more Chronic low back pain (LBP) remains the immense problem faced by doctors nowadays. Lumbar facet joint has been shown as the source of chronic pain in 21% to 41% of low back pain patients.

Epilepsy is still stigmatizing medical condition worldwide. Stigma affects the output deteriorati... more Epilepsy is still stigmatizing medical condition worldwide. Stigma affects the output deterioration such as social isolation, unemployment, lack of opportunity to marry and becomes a barrier for seekingtreatment. There has not been any scientific data on the perceived level of internal stigma of epilepsy patients in Indonesia. An accurate and simple instrument in Indonesian version is necessary to detect the level of perception of internal stigma in epilepsy patients.

Britain International of Exact Sciences (BIoEx) Journal

Stroke accounts for 10% of the world's deaths and causes severe long-term disabilities. Twen... more Stroke accounts for 10% of the world's deaths and causes severe long-term disabilities. Twenty-six million people world wide experience a stroke each year. Two-thirds represents cerebral ischemia. Age, a history of stroke or transient ischemic attack, hypertension, diabetes and heart failure characterize a stroke. Early detection with a proper treatment could improve clinical outcomes in such cases.

Polish Annals of Medicine