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Papers by dipasri bhattacharya

Research paper thumbnail of Cortisol Lowering Action and Cardiovascular Stability of Etomidate: A Comparison with Propofol in Controlled Hypertensives

Journal of evolution of medical and dental sciences, Sep 15, 2015

Research paper thumbnail of Stellate Ganglion Block- an Effective Mode of Pain Re- Lief in a Patient of Pancoast Tumour of Lung—A Case Report

Research paper thumbnail of The Indian Society for Study of Pain, Cancer Pain Special Interest Group guidelines on pharmacological management of cancer pain (Part II)

Indian Journal of Pain (Indpain), 2019

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group (SIG) guidelines ... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group (SIG) guidelines on pharmacological management of cancer pain in adults provide a structured, stepwise approach, which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire, based on the key elements of each subdraft addressing certain inconclusive areas where evidence was lacking, was made available on the ISSP website and circulated by e-mail to all the ISSP and Indian Association of Palliative Care members. We recommend that analgesics for cancer pain management should follow the World Health Organization 3-step analgesic ladder appropriate for the severity of pain. The use of paracetamol and nonsteroidal anti-inflammatory drugs alone or in combination with opioids for mild-to-moderate pain should be used. For mild-to-moderate pain, weak opioids such as tramadol, tapentadol, and codeine can be given in combination with nonopioid analgesics. We recommend morphine as the opioid of the first choice for moderate-to-severe cancer pain. Sustained-release formulations can be started 12 hourly, once the effective 24 h dose with immediate-release morphine is established. Opioid switch or rotation should be considered if there is inadequate analgesia or intolerable side effects. For opioid-induced respiratory depression, μ receptor antagonists (e.g., naloxone) must be used promptly. Antidepressants and/or anticonvulsants should be used to treat neuropathic cancer pain, and the dose should be titrated according to the clinical response and side effects. External beam radiotherapy should be offered to all patients with painful metastatic bone pain. There is evidence on use of ketamine in cancer neuropathic pain, but with no beneficial effect, thus, it is not recommended.

Research paper thumbnail of Left ventricular noncompaction in primary systemic carnitine deficiency: A rare association

Annals of Pediatric Cardiology, 2021

Left ventricular noncompaction (LVNC) is a rare phenotype of dilated cardiomyopathy. We report a ... more Left ventricular noncompaction (LVNC) is a rare phenotype of dilated cardiomyopathy. We report a child with primary systemic carnitine deficiency having associated LVNC.

Research paper thumbnail of Indian society for study of pain, cancer pain special interest group guidelines on pharmacological management of cancer pain (Part III)

Indian Journal of Palliative Care, 2020

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on pal... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on palliative care aspects in cancer pain in adults provide a structured, stepwise approach which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire based on the key elements of each sub draft addressing certain inconclusive areas where evidence was lacking was made available on the ISSP website and circulated by E-mail to all the ISSP and Indian Association of Palliative Care (IAPC) members. In a cancer care setting, approaches toward managing pain vary between ambulatory setting, home care setting, acute inpatient setting, and end-of-life care in hospice setting. We aim to expound the cancer pain management approaches in these settings. In an ambulatory palliative care setting, the WHO analgesic step ladder is used for cancer pain management. The patients with cancer pain require admission for acute inpatient palliative care unit for poorly controlled pain in ambulatory and home care settings, rapid opioid titration, titration of difficult drugs such as methadone, acute pain crisis, pain neuromodulation, and pain interventions. In a palliative home care setting, the cancer pain is usually assessed and managed by nurses and primary physicians with a limited input from the specialist physicians. In patients with cancer at the end of life, the pain should be assessed at least once a day. Moreover, physicians should be trained in assessing patients with pain who are unable to verbalize or have cognitive impairment.

Research paper thumbnail of Diagnostic Gynaecological Laparoscopy, Post-Operative Nausea and Vomiting, Intravenous Crystalloids, Antiemetics

Research paper thumbnail of Indian society for study of pain, cancer pain special interest group guidelines on pharmacological management of cancer pain (Part I)

Indian Journal of Palliative Care, 2020

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on pal... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on palliative care aspects in cancer pain in adults provide a structured, stepwise approach which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire based on the key elements of each sub draft addressing certain inconclusive areas where evidence was lacking was made available on the ISSP website and circulated by E-mail to all the ISSP and Indian Association of Palliative Care (IAPC) members. In a cancer care setting, approaches toward managing pain vary between ambulatory setting, home care setting, acute inpatient setting, and end-of-life care in hospice setting. We aim to expound the cancer pain management approaches in these settings. In an ambulatory palliative care setting, the WHO analgesic step ladder is used for cancer pain management. The patients with cancer pain require admission for acute inpatient palliative care unit for poorly controlled pain in ambulatory and home care settings, rapid opioid titration, titration of difficult drugs such as methadone, acute pain crisis, pain neuromodulation, and pain interventions. In a palliative home care setting, the cancer pain is usually assessed and managed by nurses and primary physicians with a limited input from the specialist physicians. In patients with cancer at the end of life, the pain should be assessed at least once a day. Moreover, physicians should be trained in assessing patients with pain who are unable to verbalize or have cognitive impairment.

Research paper thumbnail of Indian society for study of pain, cancer pain special interest group guidelines, for the diagnosis and assessment of cancer pain

Indian Journal of Palliative Care, 2020

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on pal... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on palliative care aspects in cancer pain in adults provide a structured, stepwise approach which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire based on the key elements of each sub draft addressing certain inconclusive areas where evidence was lacking was made available on the ISSP website and circulated by E-mail to all the ISSP and Indian Association of Palliative Care (IAPC) members. In a cancer care setting, approaches toward managing pain vary between ambulatory setting, home care setting, acute inpatient setting, and end-of-life care in hospice setting. We aim to expound the cancer pain management approaches in these settings. In an ambulatory palliative care setting, the WHO analgesic step ladder is used for cancer pain management. The patients with cancer pain require admission for acute inpatient palliative care unit for poorly controlled pain in ambulatory and home care settings, rapid opioid titration, titration of difficult drugs such as methadone, acute pain crisis, pain neuromodulation, and pain interventions. In a palliative home care setting, the cancer pain is usually assessed and managed by nurses and primary physicians with a limited input from the specialist physicians. In patients with cancer at the end of life, the pain should be assessed at least once a day. Moreover, physicians should be trained in assessing patients with pain who are unable to verbalize or have cognitive impairment.

Research paper thumbnail of Incidence of perioperative respiratory complications in patients undergoing elective open upper abdominal surgery under general anaesthesia: Smokers versus non-smokers - An observational study

Asian Journal of Medical Sciences, Mar 1, 2022

recommendations to stop smoking before elective surgery are rarely followed. Smoking impairs mucu... more recommendations to stop smoking before elective surgery are rarely followed. Smoking impairs mucus transport, pulmonary macrophage function, increases bronchial reactivity, reduces the closing capacity of the lung and increases arterial carbon monoxide

Research paper thumbnail of Clinical performance of cuffed versus uncuffed preformed endotracheal tube in pediatric patients undergoing cleft palate surgery

Saudi Journal of Anaesthesia, 2016

Background: Uncuffed endotracheal tubes are commonly used in children but due to several decade p... more Background: Uncuffed endotracheal tubes are commonly used in children but due to several decade preferred in paediatric oral surgery. Due to lack of conclusive evidences in this regard, we have conducted this study to compare post-operative morbidity following use of cuffed and uncuffed endotracheal tubes in paediatric patients undergoing cleft lip-palate surgery. Methods: This randomised controlled trial was conducted on children aged 2 to 12 years.110 patients were allocated in two parallel groups using computer generated list of random numbers. Post operative extubation stridor, sore throat, time to first oral intake and regaining of normal voice were compared between two groups. Results: The incidence of sore throat was significantly more (P value > 0.005) in patients of uncuffed group compared to cuffed group. The time to first oral intake and time to regain normal voice were significantly earlier in cuffed group compared to the other. Conclusion: With standard care, preformed cuffed ET tube has shown reduced incidence of post operative sore throat. Cuffed group has earlier oral intake and normal voice regain compared to uncuffed group.

Research paper thumbnail of Comparative Study of Post-injection Pain in Superolateral vs. Inferolateral Approach in Platelet-rich Plasma Injection for Osteoarthritis of Knee: A Retrospective Study

Journal on Recent Advances in Pain, 2018

Background: Injection site pain is not uncommon after interventional procedures particularly afte... more Background: Injection site pain is not uncommon after interventional procedures particularly after platelet-rich plasma (PRP) injection. This retrospective study aims to find out the incidence of post-injection pain after injection and any relation of post-injection pain with injection site in PRP injection for osteoarthritis of the knee. Methods: Patients of osteoarthritis of the knee who received PRP injection were grouped into two. Group A received PRP injection at the superolateral approach and group B received PRP injection at the inferolateral approach. Pre-procedure pain score on verbal rating score and post-procedure injection pain were compared in both the group and post-procedure injection pain were compared between the two groups. Results: The sample size was calculated accepting alpha error as 0.05 and power of study 80%. The inferolateral approach was thought to be more painful because of narrowing of injection space and mean pain score was presumed as 6/10 ± 1 on the verbal rating scale (VRS). The superolateral approach was considered as less painful and anticipated pain score on VRS was 5/10. The calculated sample size was 16 in each group. However, in our study sample size were 35 in group A and in group B, it was 34. Demographic profiles were compared using students t-test and Chi-square test and the two groups were found similar in age and sex ratio. Pain score of two groups was compared using the Mann-Whitney U test and was found comparable (6.31 ± 1.1 in group A and 5.76 ± 1.46 in group B). Post-injection pain at 7 days was compared between groups and was also found similar (4.62 ± 1.7 in group A and 4.74 ± 1.4 in group B) without any statistically significant difference between two groups. Pre-procedure pain (6.04 ± 1.31) in both groups compared with post-injection pain (4.68 ±1.55) of both groups and were found less than pre-injection pain and was found statistically significant (p < 0.00001). Discussion: Post-injection pain after 7 days after PRP injection were found to be less than pre-procedure injection and there is no relation pain with the injection site.

Research paper thumbnail of Effect of NIV on Postextubation Brain-Injured Patients: Looking for Evidence?

American Journal of Respiratory and Critical Care Medicine

Research paper thumbnail of Comparing helmet with mask CPAP following major abdominal surgery

Journal of Clinical Monitoring and Computing

Research paper thumbnail of A study on oral clonidine vis a vis intravenous lignocaine for attenuation of hemodynamic response to laryngoscopy and endotracheal intubation

Asian Journal of Medical Sciences, 2021

Submission: 13-10-2020 Revision: 28-01-2021 Publication: 01-03-2021 Address for Correspondence: D... more Submission: 13-10-2020 Revision: 28-01-2021 Publication: 01-03-2021 Address for Correspondence: Dr. Arunava Biswas, Associate Professor, Department of Pharmacology, Coochbehar Government Medical College & Hospital, Coochbehar -736101, West Bengal, India. Mobile No: +91-9674328329, E-mail: drabiswas@gmail.com Background: Hemodynamic change takes place during procedures like laryngoscopy and endotracheal intubation due to reflex sympathetic discharge caused by epipharyngeal and laryngopharyngeal stimulation before a surgery under general anesthesia. Aims and Objectives: The aim of the study was to compare the effectiveness of oral clonidine and intravenous lignocaine as premedicant to obtund the stress response due to such mandatory maneuvers. Materials and Methods: A prospective, randomized, double-blind, double dummy-controlled study was undertaken for 11 months at a tertiary care hospital in the eastern part of India. A total (n=100) patient aged 30 to 50 years of either sex with A...

Research paper thumbnail of Diaphragm and Lung Ultrasound Indices in Prediction of Outcome of Weaning from Mechanical Ventilation in Pediatric Intensive Care Unit

The Indian Journal of Pediatrics, 2020

Objective To predict the added value of diaphragmatic and lung ultrasound indices (US) in anticip... more Objective To predict the added value of diaphragmatic and lung ultrasound indices (US) in anticipation of the outcome of mechanical ventilation of pediatric patients in the intensive care unit. Methods This prospective study was conducted in Zagazig University, Pediatric Hospitals, PICU; Egypt. One hundred six mechanically ventilated children aged between 1 mo to 170 mo were included in the study. All patients were candidates for weaning and have been given a chance for spontaneous breathing trial (SBT), during which diaphragmatic and lung US was performed for them. The diaphragm thickening fraction (DTF), the diaphragmatic excursion and the lung US score (LUS), that included 4 US aeration forms, were assessed. Results There were statistically significant differences between patients with failed weaning and those with successful weaning regarding DTF, diaphragmatic excursion and LUS (p < 0.001). The best cutoff value of DTF, diaphragmatic excursion, and LUS for predicting weaning failure was ≥23.175%, ≥ 6.2 mm, and ≥ 12 with an AUC (area under curve) of 0.932, 0.876, and 0.934, respectively. Conclusions Diaphragmatic and lung US add a quick, accurate and non-invasive indices to the weaning readiness parameters compared to the other standard parameters alone. So, it is recommended to be added to the predictive parameters of weaning outcome.

Research paper thumbnail of Letter to the editor: “Clinical characteristics, physiological features, and outcomes associated with hypercapnia in patients with acute hypoxemic respiratory failure due to COVID-19---insights from the PRoVENT-COVID study”

Journal of Critical Care, Oct 1, 2022

Research paper thumbnail of Managing patients with multiple rib fractures outside the ICU: Can high flow nasal cannula be a game changer?

Research paper thumbnail of Non-invasive Ventilation Delivered by Helmet vs Face Mask in Patients with COVID-19 Infection: Additional Measures to Reap Further Benefits

Indian Journal of Critical Care Medicine

Research paper thumbnail of Postoperative pulmonary complications after minimally invasive esophagectomy: some practical issues

General Thoracic and Cardiovascular Surgery

Research paper thumbnail of Comparison of Ultrasonogaphy Vs Fluoroscopy Guided Coeliac Plexus Block for Relief of Pain in Chronic Pancreatitis–An Observational Study

Archives of Anesthesiology, 2019

Inroduction: This study was done to compare between Ultrasonography Vs. Fluoroscopy Guided Coelia... more Inroduction: This study was done to compare between Ultrasonography Vs. Fluoroscopy Guided Coeliac plexus block for relief of pain in chronic pancreatitis. The patients were undergoingtreatment at medicine/ gastroenterology/surgery departments of R.G.Kar Medical College(Kolkata) for more than 6 months, not responding to conservative treatment and were referred to pain OPD for subsequent pain management.

Research paper thumbnail of Cortisol Lowering Action and Cardiovascular Stability of Etomidate: A Comparison with Propofol in Controlled Hypertensives

Journal of evolution of medical and dental sciences, Sep 15, 2015

Research paper thumbnail of Stellate Ganglion Block- an Effective Mode of Pain Re- Lief in a Patient of Pancoast Tumour of Lung—A Case Report

Research paper thumbnail of The Indian Society for Study of Pain, Cancer Pain Special Interest Group guidelines on pharmacological management of cancer pain (Part II)

Indian Journal of Pain (Indpain), 2019

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group (SIG) guidelines ... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group (SIG) guidelines on pharmacological management of cancer pain in adults provide a structured, stepwise approach, which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire, based on the key elements of each subdraft addressing certain inconclusive areas where evidence was lacking, was made available on the ISSP website and circulated by e-mail to all the ISSP and Indian Association of Palliative Care members. We recommend that analgesics for cancer pain management should follow the World Health Organization 3-step analgesic ladder appropriate for the severity of pain. The use of paracetamol and nonsteroidal anti-inflammatory drugs alone or in combination with opioids for mild-to-moderate pain should be used. For mild-to-moderate pain, weak opioids such as tramadol, tapentadol, and codeine can be given in combination with nonopioid analgesics. We recommend morphine as the opioid of the first choice for moderate-to-severe cancer pain. Sustained-release formulations can be started 12 hourly, once the effective 24 h dose with immediate-release morphine is established. Opioid switch or rotation should be considered if there is inadequate analgesia or intolerable side effects. For opioid-induced respiratory depression, μ receptor antagonists (e.g., naloxone) must be used promptly. Antidepressants and/or anticonvulsants should be used to treat neuropathic cancer pain, and the dose should be titrated according to the clinical response and side effects. External beam radiotherapy should be offered to all patients with painful metastatic bone pain. There is evidence on use of ketamine in cancer neuropathic pain, but with no beneficial effect, thus, it is not recommended.

Research paper thumbnail of Left ventricular noncompaction in primary systemic carnitine deficiency: A rare association

Annals of Pediatric Cardiology, 2021

Left ventricular noncompaction (LVNC) is a rare phenotype of dilated cardiomyopathy. We report a ... more Left ventricular noncompaction (LVNC) is a rare phenotype of dilated cardiomyopathy. We report a child with primary systemic carnitine deficiency having associated LVNC.

Research paper thumbnail of Indian society for study of pain, cancer pain special interest group guidelines on pharmacological management of cancer pain (Part III)

Indian Journal of Palliative Care, 2020

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on pal... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on palliative care aspects in cancer pain in adults provide a structured, stepwise approach which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire based on the key elements of each sub draft addressing certain inconclusive areas where evidence was lacking was made available on the ISSP website and circulated by E-mail to all the ISSP and Indian Association of Palliative Care (IAPC) members. In a cancer care setting, approaches toward managing pain vary between ambulatory setting, home care setting, acute inpatient setting, and end-of-life care in hospice setting. We aim to expound the cancer pain management approaches in these settings. In an ambulatory palliative care setting, the WHO analgesic step ladder is used for cancer pain management. The patients with cancer pain require admission for acute inpatient palliative care unit for poorly controlled pain in ambulatory and home care settings, rapid opioid titration, titration of difficult drugs such as methadone, acute pain crisis, pain neuromodulation, and pain interventions. In a palliative home care setting, the cancer pain is usually assessed and managed by nurses and primary physicians with a limited input from the specialist physicians. In patients with cancer at the end of life, the pain should be assessed at least once a day. Moreover, physicians should be trained in assessing patients with pain who are unable to verbalize or have cognitive impairment.

Research paper thumbnail of Diagnostic Gynaecological Laparoscopy, Post-Operative Nausea and Vomiting, Intravenous Crystalloids, Antiemetics

Research paper thumbnail of Indian society for study of pain, cancer pain special interest group guidelines on pharmacological management of cancer pain (Part I)

Indian Journal of Palliative Care, 2020

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on pal... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on palliative care aspects in cancer pain in adults provide a structured, stepwise approach which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire based on the key elements of each sub draft addressing certain inconclusive areas where evidence was lacking was made available on the ISSP website and circulated by E-mail to all the ISSP and Indian Association of Palliative Care (IAPC) members. In a cancer care setting, approaches toward managing pain vary between ambulatory setting, home care setting, acute inpatient setting, and end-of-life care in hospice setting. We aim to expound the cancer pain management approaches in these settings. In an ambulatory palliative care setting, the WHO analgesic step ladder is used for cancer pain management. The patients with cancer pain require admission for acute inpatient palliative care unit for poorly controlled pain in ambulatory and home care settings, rapid opioid titration, titration of difficult drugs such as methadone, acute pain crisis, pain neuromodulation, and pain interventions. In a palliative home care setting, the cancer pain is usually assessed and managed by nurses and primary physicians with a limited input from the specialist physicians. In patients with cancer at the end of life, the pain should be assessed at least once a day. Moreover, physicians should be trained in assessing patients with pain who are unable to verbalize or have cognitive impairment.

Research paper thumbnail of Indian society for study of pain, cancer pain special interest group guidelines, for the diagnosis and assessment of cancer pain

Indian Journal of Palliative Care, 2020

The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on pal... more The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group guidelines on palliative care aspects in cancer pain in adults provide a structured, stepwise approach which will help to improve the management of cancer pain and to provide the patients with a minimally acceptable quality of life. The guidelines have been developed based on the available literature and evidence, to suit the needs, patient population, and situations in India. A questionnaire based on the key elements of each sub draft addressing certain inconclusive areas where evidence was lacking was made available on the ISSP website and circulated by E-mail to all the ISSP and Indian Association of Palliative Care (IAPC) members. In a cancer care setting, approaches toward managing pain vary between ambulatory setting, home care setting, acute inpatient setting, and end-of-life care in hospice setting. We aim to expound the cancer pain management approaches in these settings. In an ambulatory palliative care setting, the WHO analgesic step ladder is used for cancer pain management. The patients with cancer pain require admission for acute inpatient palliative care unit for poorly controlled pain in ambulatory and home care settings, rapid opioid titration, titration of difficult drugs such as methadone, acute pain crisis, pain neuromodulation, and pain interventions. In a palliative home care setting, the cancer pain is usually assessed and managed by nurses and primary physicians with a limited input from the specialist physicians. In patients with cancer at the end of life, the pain should be assessed at least once a day. Moreover, physicians should be trained in assessing patients with pain who are unable to verbalize or have cognitive impairment.

Research paper thumbnail of Incidence of perioperative respiratory complications in patients undergoing elective open upper abdominal surgery under general anaesthesia: Smokers versus non-smokers - An observational study

Asian Journal of Medical Sciences, Mar 1, 2022

recommendations to stop smoking before elective surgery are rarely followed. Smoking impairs mucu... more recommendations to stop smoking before elective surgery are rarely followed. Smoking impairs mucus transport, pulmonary macrophage function, increases bronchial reactivity, reduces the closing capacity of the lung and increases arterial carbon monoxide

Research paper thumbnail of Clinical performance of cuffed versus uncuffed preformed endotracheal tube in pediatric patients undergoing cleft palate surgery

Saudi Journal of Anaesthesia, 2016

Background: Uncuffed endotracheal tubes are commonly used in children but due to several decade p... more Background: Uncuffed endotracheal tubes are commonly used in children but due to several decade preferred in paediatric oral surgery. Due to lack of conclusive evidences in this regard, we have conducted this study to compare post-operative morbidity following use of cuffed and uncuffed endotracheal tubes in paediatric patients undergoing cleft lip-palate surgery. Methods: This randomised controlled trial was conducted on children aged 2 to 12 years.110 patients were allocated in two parallel groups using computer generated list of random numbers. Post operative extubation stridor, sore throat, time to first oral intake and regaining of normal voice were compared between two groups. Results: The incidence of sore throat was significantly more (P value > 0.005) in patients of uncuffed group compared to cuffed group. The time to first oral intake and time to regain normal voice were significantly earlier in cuffed group compared to the other. Conclusion: With standard care, preformed cuffed ET tube has shown reduced incidence of post operative sore throat. Cuffed group has earlier oral intake and normal voice regain compared to uncuffed group.

Research paper thumbnail of Comparative Study of Post-injection Pain in Superolateral vs. Inferolateral Approach in Platelet-rich Plasma Injection for Osteoarthritis of Knee: A Retrospective Study

Journal on Recent Advances in Pain, 2018

Background: Injection site pain is not uncommon after interventional procedures particularly afte... more Background: Injection site pain is not uncommon after interventional procedures particularly after platelet-rich plasma (PRP) injection. This retrospective study aims to find out the incidence of post-injection pain after injection and any relation of post-injection pain with injection site in PRP injection for osteoarthritis of the knee. Methods: Patients of osteoarthritis of the knee who received PRP injection were grouped into two. Group A received PRP injection at the superolateral approach and group B received PRP injection at the inferolateral approach. Pre-procedure pain score on verbal rating score and post-procedure injection pain were compared in both the group and post-procedure injection pain were compared between the two groups. Results: The sample size was calculated accepting alpha error as 0.05 and power of study 80%. The inferolateral approach was thought to be more painful because of narrowing of injection space and mean pain score was presumed as 6/10 ± 1 on the verbal rating scale (VRS). The superolateral approach was considered as less painful and anticipated pain score on VRS was 5/10. The calculated sample size was 16 in each group. However, in our study sample size were 35 in group A and in group B, it was 34. Demographic profiles were compared using students t-test and Chi-square test and the two groups were found similar in age and sex ratio. Pain score of two groups was compared using the Mann-Whitney U test and was found comparable (6.31 ± 1.1 in group A and 5.76 ± 1.46 in group B). Post-injection pain at 7 days was compared between groups and was also found similar (4.62 ± 1.7 in group A and 4.74 ± 1.4 in group B) without any statistically significant difference between two groups. Pre-procedure pain (6.04 ± 1.31) in both groups compared with post-injection pain (4.68 ±1.55) of both groups and were found less than pre-injection pain and was found statistically significant (p < 0.00001). Discussion: Post-injection pain after 7 days after PRP injection were found to be less than pre-procedure injection and there is no relation pain with the injection site.

Research paper thumbnail of Effect of NIV on Postextubation Brain-Injured Patients: Looking for Evidence?

American Journal of Respiratory and Critical Care Medicine

Research paper thumbnail of Comparing helmet with mask CPAP following major abdominal surgery

Journal of Clinical Monitoring and Computing

Research paper thumbnail of A study on oral clonidine vis a vis intravenous lignocaine for attenuation of hemodynamic response to laryngoscopy and endotracheal intubation

Asian Journal of Medical Sciences, 2021

Submission: 13-10-2020 Revision: 28-01-2021 Publication: 01-03-2021 Address for Correspondence: D... more Submission: 13-10-2020 Revision: 28-01-2021 Publication: 01-03-2021 Address for Correspondence: Dr. Arunava Biswas, Associate Professor, Department of Pharmacology, Coochbehar Government Medical College & Hospital, Coochbehar -736101, West Bengal, India. Mobile No: +91-9674328329, E-mail: drabiswas@gmail.com Background: Hemodynamic change takes place during procedures like laryngoscopy and endotracheal intubation due to reflex sympathetic discharge caused by epipharyngeal and laryngopharyngeal stimulation before a surgery under general anesthesia. Aims and Objectives: The aim of the study was to compare the effectiveness of oral clonidine and intravenous lignocaine as premedicant to obtund the stress response due to such mandatory maneuvers. Materials and Methods: A prospective, randomized, double-blind, double dummy-controlled study was undertaken for 11 months at a tertiary care hospital in the eastern part of India. A total (n=100) patient aged 30 to 50 years of either sex with A...

Research paper thumbnail of Diaphragm and Lung Ultrasound Indices in Prediction of Outcome of Weaning from Mechanical Ventilation in Pediatric Intensive Care Unit

The Indian Journal of Pediatrics, 2020

Objective To predict the added value of diaphragmatic and lung ultrasound indices (US) in anticip... more Objective To predict the added value of diaphragmatic and lung ultrasound indices (US) in anticipation of the outcome of mechanical ventilation of pediatric patients in the intensive care unit. Methods This prospective study was conducted in Zagazig University, Pediatric Hospitals, PICU; Egypt. One hundred six mechanically ventilated children aged between 1 mo to 170 mo were included in the study. All patients were candidates for weaning and have been given a chance for spontaneous breathing trial (SBT), during which diaphragmatic and lung US was performed for them. The diaphragm thickening fraction (DTF), the diaphragmatic excursion and the lung US score (LUS), that included 4 US aeration forms, were assessed. Results There were statistically significant differences between patients with failed weaning and those with successful weaning regarding DTF, diaphragmatic excursion and LUS (p < 0.001). The best cutoff value of DTF, diaphragmatic excursion, and LUS for predicting weaning failure was ≥23.175%, ≥ 6.2 mm, and ≥ 12 with an AUC (area under curve) of 0.932, 0.876, and 0.934, respectively. Conclusions Diaphragmatic and lung US add a quick, accurate and non-invasive indices to the weaning readiness parameters compared to the other standard parameters alone. So, it is recommended to be added to the predictive parameters of weaning outcome.

Research paper thumbnail of Letter to the editor: “Clinical characteristics, physiological features, and outcomes associated with hypercapnia in patients with acute hypoxemic respiratory failure due to COVID-19---insights from the PRoVENT-COVID study”

Journal of Critical Care, Oct 1, 2022

Research paper thumbnail of Managing patients with multiple rib fractures outside the ICU: Can high flow nasal cannula be a game changer?

Research paper thumbnail of Non-invasive Ventilation Delivered by Helmet vs Face Mask in Patients with COVID-19 Infection: Additional Measures to Reap Further Benefits

Indian Journal of Critical Care Medicine

Research paper thumbnail of Postoperative pulmonary complications after minimally invasive esophagectomy: some practical issues

General Thoracic and Cardiovascular Surgery

Research paper thumbnail of Comparison of Ultrasonogaphy Vs Fluoroscopy Guided Coeliac Plexus Block for Relief of Pain in Chronic Pancreatitis–An Observational Study

Archives of Anesthesiology, 2019

Inroduction: This study was done to compare between Ultrasonography Vs. Fluoroscopy Guided Coelia... more Inroduction: This study was done to compare between Ultrasonography Vs. Fluoroscopy Guided Coeliac plexus block for relief of pain in chronic pancreatitis. The patients were undergoingtreatment at medicine/ gastroenterology/surgery departments of R.G.Kar Medical College(Kolkata) for more than 6 months, not responding to conservative treatment and were referred to pain OPD for subsequent pain management.