fauzul muna - Academia.edu (original) (raw)
Papers by fauzul muna
Jundishapur Journal of Microbiology
Background: In Corynebacterium diphtheriae, the dtxR gene plays a role in regulating diphtheria t... more Background: In Corynebacterium diphtheriae, the dtxR gene plays a role in regulating diphtheria toxin synthesis. The dtxR gene is often used as a marker for identifying C. diphtheriae by the polymerase chain reaction (PCR) method because it is present in all strains of this bacterium. Mutations in the dtxR gene can cause the over-synthesis of diphtheria toxin and reduce PCR assays' sensitivity. Objectives: This study aimed to describe the polymorphisms in the dtxR gene of C. diphtheriae isolated from a diphtheria outbreak in Indonesia. Methods: Forty-eight isolates of C. diphtheriae were obtained from clinical samples (throat/nasopharyngeal swabs) of diphtheria cases and close contacts. The isolates were revived on a Blood Agar Plate (BAP), bacterial colonies were harvested, and deoxyribonucleic acid (DNA) was extracted. The DNA sequencing was carried out using a Whole-genome Sequencing (WGS) approach. The data were converted and analyzed with U-gene software. The dtxR gene anal...
International Conference on Agromedicine and Tropical Diseases, 2020
Brucellosis is a zoonotic disease and caused by the bacterium Brucella sp. This disease is one of... more Brucellosis is a zoonotic disease and caused by the bacterium Brucella sp. This disease is one of the infectious diseases that has spread throughout the world. Brucellosis is still an endemic disease in Indonesia with varying prevalence in various regions. The World Health Organization (WHO) estimates that as many as 500,000 new cases of brucellosis appear every year so that it is considered the most common zoonotic disease in the world. Transmission to humans occurs mainly through direct contact with infected animals, drinking milk from infected animals, and breathing air contaminated by bacteria that cause brucellosis. The data used for the analysis is a report on income and quarantine actions on imported Australian cattle imported through Soekarno Hatta International Airport. Quarantine measures for 200 Frisian Holstein (FH) imported dairy cows were carried out from October 16, 2018, to November 15, 2018. Based on the Certificate of Health to Accompany Animals or Animal Reproduct...
Jundishapur Journal of Microbiology
Background: Corynebacterium diphtheriae, C. ulcerans, and C. pseudotuberculosis are known as diph... more Background: Corynebacterium diphtheriae, C. ulcerans, and C. pseudotuberculosis are known as diphtheria-causing bacteria. Although diphtheria therapy is administered based on the clinical manifestations, some cases are mild and atypical. The immediate and accurate identification of diphtheria-causing bacteria is of paramount importance to prevent the spread of the disease and provide case management as early as possible. Unfortunately, conventional methods as the gold standard are time-consuming. Objectives: This study aimed to develop and implement a multiplex real-time PCR with the dtxR and tox genes as the target to identify three species of diphtheria-causing bacteria and screen their toxigenicity quickly and accurately. Methods: The research sample encompassed seven reference strains, one synthetic DNA, 30 archived isolates, and 924 clinical specimens isolated from 311 diphtheria cases and 613 close contacts. The conventional methods as the gold standard and the established PCR...
PLOS ONE, Apr 20, 2022
Pertussis cases have been reported most frequently in developed countries, but they are predicted... more Pertussis cases have been reported most frequently in developed countries, but they are predicted to be the most prevalent in developing countries. Indonesia, a developing country, routinely conducts case-based surveillance for pertussis. We reviewed the data on pertussis cases and close contacts based on clinical sample documents examined in the National Reference Laboratory for pertussis, Indonesia (2016-2020). Our objective was to analyze the laboratory and epidemiological aspects of pertussis cases and close contacts, particularly to evaluate the implementation of a 5-year case-based surveillance of pertussis in Indonesia. Data were collected from sample documents and annual laboratory reports between January 2016 and December 2020. We analyzed the proportion of pertussis cases and close contacts by geographic region, year, age, and sex. We used the χ 2 test to correlate the laboratory and epidemiological data. In total, 274 clinical cases of pertussis and 491 close contacts were recorded in 15 provinces. The peak number of cases occurred in 2019, with a positivity rate (percentage of laboratory-confirmed cases) of 41.23% (47/114). Clinical cases were dominated by infants aged <1 year (55.5%), and 52.9% of them were aged <6 months. Similarly, 72.3% (68/94) of the laboratory-confirmed cases were infants. Both clinical cases and positivity rates tended to be higher in females (155 cases, 38.1%) than in males (119 cases, 29.4%). No confirmed cases were found in children aged �10 years, although positive results still occurred in close contact. Age-group and laboratory-confirmed cases were correlated (p = 0.00). Clinical and confirmed cases of pertussis occurred mostly in the early age group and may be lower in those aged �10 years, especially in confirmed cases. New policies
SINASIS (Seminar Nasional Sains), Jul 3, 2021
Seminar Nasional Riset Kedokteran, 2020
SINASIS (Seminar Nasional Sains), Jul 3, 2021
Information about the susceptibility pattern of diphtheria-causing bacteria to antibiotics especi... more Information about the susceptibility pattern of diphtheria-causing bacteria to antibiotics especially penicillin as a first-line antibiotic is needed. This study was aimed to obtain recent information on the susceptibility of Corynebacterium diphtheriae to penicillin. A total of 40 C. diphtheriae isolated from several provinces of Indonesia in 2018 were used as samples. Secondary data, including isolate origin, biotype, and toxigenicity obtained from reporting and recording data of diphtheria examination conducted in Research Laboratory for Infectious Diseases Prof. dr. Sri Oemijati. Antibiotic susceptibility test was carried out by using the E-test method. Simple statistical analysis by Chi-Square was used to analyze the correlation between bacterial susceptibility patterns and isolate characteristics. The results showed that the decreased susceptibility to penicillin with intermediate criteria included 9 (22.5%) samples examined. Statistical analysis indicated the correlation betw...
One Health, 2021
The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One ... more The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One Health” approach, known as the Global Surveillance ESBL E. coli Tricycle Project. We describe the implementation of the Tricycle Project (pilot) in Indonesia, focusing on its results, challenges and recommendations. The samples were 116 patients with bloodstream infections caused by ESBL E. coli, 100 rectal swabs collected from pregnant women, 240 cecums of broiler, and 119 environmental samples, using the standardized method according to the guidelines. ESBL-producing E. coli was found in 40 (40%) of the 100 pregnant women, while the proportion of ESBL-producing E. coli was 57.7% among the total E. coli-induced bloodstream infections. ESBL-producing E. coli was isolated from 161 (67.1%) out of 240 broilers. On the other hand, the average concentration of E. coli in the water samples was 2.0 × 108 CFU/100 mL, and the ratio of ESBL-producing E. coli was 12.8% of total E. coli. Unfortunate...
One Health, 2021
The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One ... more The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One Health” approach, known as the Global Surveillance ESBL E. coli Tricycle Project. We describe the implementation of the Tricycle Project (pilot) in Indonesia, focusing on its results, challenges and recommendations. The samples were 116 patients with bloodstream infections caused by ESBL E. coli, 100 rectal swabs collected from pregnant women, 240 cecums of broiler, and 119 environmental samples, using the standardized method according to the guidelines. ESBL-producing E. coli was found in 40 (40%) of the 100 pregnant women, while the proportion of ESBL-producing E. coli was 57.7% among the total E. coli-induced bloodstream infections. ESBL-producing E. coli was isolated from 161 (67.1%) out of 240 broilers. On the other hand, the average concentration of E. coli in the water samples was 2.0 × 108 CFU/100 mL, and the ratio of ESBL-producing E. coli was 12.8% of total E. coli. Unfortunate...
Biotechnology has brought big changes in biology. The development of biotechnology is also widely... more Biotechnology has brought big changes in biology. The development of biotechnology is also widely used in supporting modern medical science. Many biotechnology-based examination methods are currently developing, including methods of diagnosing diseases to detect pathogenic bacteria. This paper discusses the advantages of multiplex polymerase chain reaction (PCR) methods for bacterial detection from library research results and related reports. Identification of bacteria as a source of infection can be done by conventional methods such as microscopic examination, culture, and serology. This method is based on the morphology and characteristics of the bacteria to be identified. The conventional method with culture medium is the gold standard in diagnosing diseases caused by bacterial infections. Life science, especially in the field of molecular biology, has experienced rapid development and accelerated the pace of biotechnology development. Molecular biology is a branch of biology th...
One Health, 2021
The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One ... more The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One Health” approach, known as the Global Surveillance ESBL E. coli Tricycle Project. We describe the implementation of the Tricycle Project (pilot) in Indonesia, focusing on its results, challenges and recommendations. The samples were 116 patients with bloodstream infections caused by ESBL E. coli, 100 rectal swabs collected from pregnant women, 240 cecums of broiler, and 119 environmental samples, using the standardized method according to the guidelines. ESBL-producing E. coli was found in 40 (40%) of the 100 pregnant women, while the proportion of ESBL-producing E. coli was 57.7% among the total E. coli-induced bloodstream infections. ESBL-producing E. coli was isolated from 161 (67.1%) out of 240 broilers. On the other hand, the average concentration of E. coli in the water samples was 2.0 × 108 CFU/100 mL, and the ratio of ESBL-producing E. coli was 12.8% of total E. coli. Unfortunate...
Water is a primary need of the community which is very important, especially to be consumed as dr... more Water is a primary need of the community which is very important, especially to be consumed as drinking water. The amount of drinking water needed by the community continues to increase in line with population growth. The rapidly increasing population is in fact not offset by the availability of enough clean water for drinking. Currently drinking water is used for consumption of various types. Most high economic communities consume Bottled Drinking Water (AMDK) because it is more practical and is considered to be more hygienic. While others choose to consume Refill Drinking Water (AMIU) produced by the Refill Drinking Water Depot (DAMIU) as an alternative because it is more economical. In recent years the development of mineral refill drinking water depots and RO (Reverse Osmosis) businesses has mushroomed. The quality of water that is ready to be offered to the community is sufficiently maintained because the water is supplied directly from mountain springs which depend on the refi...
Kasus foodborne diseases di dunia mencapai sampai 250 kasus yang berbeda dan didominasi oleh peny... more Kasus foodborne diseases di dunia mencapai sampai 250 kasus yang berbeda dan didominasi oleh penyakit infeksi. Foodborne diseases merupakan penyakit yang biasanya bersifat infeksi atau racun yang diakibatkan oleh sumber infeksi yang masuk ke dalam tubuh bersama makanan yang dicerna. Makanan menjadi media penularan penyakit yang baik dalam menghantarkan mikroorganisme patogen sampai ke tempat kolonisasi di dalam tubuh. Foodborne diseases menjadi penyebab morbiditas dan mortalitas yang penting dan mendapat perhatian serius di negara berkembang maupun negara maju. Tulisan ini merupakan studi literatur dengan mengumpulkan data dari hasil penelusuran berbagai sumber seperti jurnal ilmiah, laporan penelitian maupun media online. Gejala foodborne diseases antara lain sakit pada saluran gastrointestinal, neurological, gynaecological, immunological dan gejala lain. Selain itu juga dapat mengakibatkan kegagalan berbagai organ, kanker sampai kematian. Foodborne diseases dibedakan menjadi yaitu...
Prosiding Seminar Nasional Masyarakat Biodiversitas Indonesia, 2019
Abstract. Khariri, Muna F. 2019. The proportion of parasite species that are the cause of malaria... more Abstract. Khariri, Muna F. 2019. The proportion of parasite species that are the cause of malaria infection in Indonesia base on result of Basic Health Research (Riskesdas). Pros Sem Nas Masy Biodiv Indon 5: 38-41. Indonesia has a global Millennium Development Goals (MDGs) commitment to eradicate malaria. Malaria is one of the reemerging diseases in recent years which is marked by an increasing trend in cases in Indonesia. Although Plasmodium has many types, there are only 5 types that can cause Malaria. Malaria laboratory diagnosis can provide information on the type of parasite that causes infection. One of the laboratory examination techniques can be done with Rapid Dianostic Test (RDT). Analysis was carried out on data from the Basic Health Research Results (Riskesdas) 2010 and 2013 in Indonesia. The data obtained were analyzed descriptively. Based on the results of the RDT examination, in Riskesdas 2013 was found that the proportion of the population with positive malaria was 1...
IOP Conference Series: Earth and Environmental Science
Diarrheal diseases are the second cause of the high morbidity and mortality in children under fiv... more Diarrheal diseases are the second cause of the high morbidity and mortality in children under five years old. According to the Basic Health Survey 2018 conducted by the Ministry of Health, the prevalence of diarrheal diseases among children under five years old that were diagnosed by healthcare workers was 11.0%. The aim of this study was to describe the enteric pathogen isolated from children with diarrhea. The study was conducted in five cities in Indonesia: Jakarta, Serang, Denpasar, Makassar, and Mataram. The Inclusion criteria were children aged one month to five years old, with diarrhea that was diagnosed by a healthcare worker. The rectal swabs were sent to the Centre for Research and Development for Biomedical and Basic Health Technology, National Institute of Health Research and Development, Ministry of Health in Jakarta. Virus and Enterotoxigenic Escherichia coli (ETEC) identification by using multiplex PCR from Seegene, meanwhile bacteria identified by conventional method...
Jundishapur Journal of Microbiology
Background: In Corynebacterium diphtheriae, the dtxR gene plays a role in regulating diphtheria t... more Background: In Corynebacterium diphtheriae, the dtxR gene plays a role in regulating diphtheria toxin synthesis. The dtxR gene is often used as a marker for identifying C. diphtheriae by the polymerase chain reaction (PCR) method because it is present in all strains of this bacterium. Mutations in the dtxR gene can cause the over-synthesis of diphtheria toxin and reduce PCR assays' sensitivity. Objectives: This study aimed to describe the polymorphisms in the dtxR gene of C. diphtheriae isolated from a diphtheria outbreak in Indonesia. Methods: Forty-eight isolates of C. diphtheriae were obtained from clinical samples (throat/nasopharyngeal swabs) of diphtheria cases and close contacts. The isolates were revived on a Blood Agar Plate (BAP), bacterial colonies were harvested, and deoxyribonucleic acid (DNA) was extracted. The DNA sequencing was carried out using a Whole-genome Sequencing (WGS) approach. The data were converted and analyzed with U-gene software. The dtxR gene anal...
International Conference on Agromedicine and Tropical Diseases, 2020
Brucellosis is a zoonotic disease and caused by the bacterium Brucella sp. This disease is one of... more Brucellosis is a zoonotic disease and caused by the bacterium Brucella sp. This disease is one of the infectious diseases that has spread throughout the world. Brucellosis is still an endemic disease in Indonesia with varying prevalence in various regions. The World Health Organization (WHO) estimates that as many as 500,000 new cases of brucellosis appear every year so that it is considered the most common zoonotic disease in the world. Transmission to humans occurs mainly through direct contact with infected animals, drinking milk from infected animals, and breathing air contaminated by bacteria that cause brucellosis. The data used for the analysis is a report on income and quarantine actions on imported Australian cattle imported through Soekarno Hatta International Airport. Quarantine measures for 200 Frisian Holstein (FH) imported dairy cows were carried out from October 16, 2018, to November 15, 2018. Based on the Certificate of Health to Accompany Animals or Animal Reproduct...
Jundishapur Journal of Microbiology
Background: Corynebacterium diphtheriae, C. ulcerans, and C. pseudotuberculosis are known as diph... more Background: Corynebacterium diphtheriae, C. ulcerans, and C. pseudotuberculosis are known as diphtheria-causing bacteria. Although diphtheria therapy is administered based on the clinical manifestations, some cases are mild and atypical. The immediate and accurate identification of diphtheria-causing bacteria is of paramount importance to prevent the spread of the disease and provide case management as early as possible. Unfortunately, conventional methods as the gold standard are time-consuming. Objectives: This study aimed to develop and implement a multiplex real-time PCR with the dtxR and tox genes as the target to identify three species of diphtheria-causing bacteria and screen their toxigenicity quickly and accurately. Methods: The research sample encompassed seven reference strains, one synthetic DNA, 30 archived isolates, and 924 clinical specimens isolated from 311 diphtheria cases and 613 close contacts. The conventional methods as the gold standard and the established PCR...
PLOS ONE, Apr 20, 2022
Pertussis cases have been reported most frequently in developed countries, but they are predicted... more Pertussis cases have been reported most frequently in developed countries, but they are predicted to be the most prevalent in developing countries. Indonesia, a developing country, routinely conducts case-based surveillance for pertussis. We reviewed the data on pertussis cases and close contacts based on clinical sample documents examined in the National Reference Laboratory for pertussis, Indonesia (2016-2020). Our objective was to analyze the laboratory and epidemiological aspects of pertussis cases and close contacts, particularly to evaluate the implementation of a 5-year case-based surveillance of pertussis in Indonesia. Data were collected from sample documents and annual laboratory reports between January 2016 and December 2020. We analyzed the proportion of pertussis cases and close contacts by geographic region, year, age, and sex. We used the χ 2 test to correlate the laboratory and epidemiological data. In total, 274 clinical cases of pertussis and 491 close contacts were recorded in 15 provinces. The peak number of cases occurred in 2019, with a positivity rate (percentage of laboratory-confirmed cases) of 41.23% (47/114). Clinical cases were dominated by infants aged <1 year (55.5%), and 52.9% of them were aged <6 months. Similarly, 72.3% (68/94) of the laboratory-confirmed cases were infants. Both clinical cases and positivity rates tended to be higher in females (155 cases, 38.1%) than in males (119 cases, 29.4%). No confirmed cases were found in children aged �10 years, although positive results still occurred in close contact. Age-group and laboratory-confirmed cases were correlated (p = 0.00). Clinical and confirmed cases of pertussis occurred mostly in the early age group and may be lower in those aged �10 years, especially in confirmed cases. New policies
SINASIS (Seminar Nasional Sains), Jul 3, 2021
Seminar Nasional Riset Kedokteran, 2020
SINASIS (Seminar Nasional Sains), Jul 3, 2021
Information about the susceptibility pattern of diphtheria-causing bacteria to antibiotics especi... more Information about the susceptibility pattern of diphtheria-causing bacteria to antibiotics especially penicillin as a first-line antibiotic is needed. This study was aimed to obtain recent information on the susceptibility of Corynebacterium diphtheriae to penicillin. A total of 40 C. diphtheriae isolated from several provinces of Indonesia in 2018 were used as samples. Secondary data, including isolate origin, biotype, and toxigenicity obtained from reporting and recording data of diphtheria examination conducted in Research Laboratory for Infectious Diseases Prof. dr. Sri Oemijati. Antibiotic susceptibility test was carried out by using the E-test method. Simple statistical analysis by Chi-Square was used to analyze the correlation between bacterial susceptibility patterns and isolate characteristics. The results showed that the decreased susceptibility to penicillin with intermediate criteria included 9 (22.5%) samples examined. Statistical analysis indicated the correlation betw...
One Health, 2021
The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One ... more The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One Health” approach, known as the Global Surveillance ESBL E. coli Tricycle Project. We describe the implementation of the Tricycle Project (pilot) in Indonesia, focusing on its results, challenges and recommendations. The samples were 116 patients with bloodstream infections caused by ESBL E. coli, 100 rectal swabs collected from pregnant women, 240 cecums of broiler, and 119 environmental samples, using the standardized method according to the guidelines. ESBL-producing E. coli was found in 40 (40%) of the 100 pregnant women, while the proportion of ESBL-producing E. coli was 57.7% among the total E. coli-induced bloodstream infections. ESBL-producing E. coli was isolated from 161 (67.1%) out of 240 broilers. On the other hand, the average concentration of E. coli in the water samples was 2.0 × 108 CFU/100 mL, and the ratio of ESBL-producing E. coli was 12.8% of total E. coli. Unfortunate...
One Health, 2021
The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One ... more The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One Health” approach, known as the Global Surveillance ESBL E. coli Tricycle Project. We describe the implementation of the Tricycle Project (pilot) in Indonesia, focusing on its results, challenges and recommendations. The samples were 116 patients with bloodstream infections caused by ESBL E. coli, 100 rectal swabs collected from pregnant women, 240 cecums of broiler, and 119 environmental samples, using the standardized method according to the guidelines. ESBL-producing E. coli was found in 40 (40%) of the 100 pregnant women, while the proportion of ESBL-producing E. coli was 57.7% among the total E. coli-induced bloodstream infections. ESBL-producing E. coli was isolated from 161 (67.1%) out of 240 broilers. On the other hand, the average concentration of E. coli in the water samples was 2.0 × 108 CFU/100 mL, and the ratio of ESBL-producing E. coli was 12.8% of total E. coli. Unfortunate...
Biotechnology has brought big changes in biology. The development of biotechnology is also widely... more Biotechnology has brought big changes in biology. The development of biotechnology is also widely used in supporting modern medical science. Many biotechnology-based examination methods are currently developing, including methods of diagnosing diseases to detect pathogenic bacteria. This paper discusses the advantages of multiplex polymerase chain reaction (PCR) methods for bacterial detection from library research results and related reports. Identification of bacteria as a source of infection can be done by conventional methods such as microscopic examination, culture, and serology. This method is based on the morphology and characteristics of the bacteria to be identified. The conventional method with culture medium is the gold standard in diagnosing diseases caused by bacterial infections. Life science, especially in the field of molecular biology, has experienced rapid development and accelerated the pace of biotechnology development. Molecular biology is a branch of biology th...
One Health, 2021
The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One ... more The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One Health” approach, known as the Global Surveillance ESBL E. coli Tricycle Project. We describe the implementation of the Tricycle Project (pilot) in Indonesia, focusing on its results, challenges and recommendations. The samples were 116 patients with bloodstream infections caused by ESBL E. coli, 100 rectal swabs collected from pregnant women, 240 cecums of broiler, and 119 environmental samples, using the standardized method according to the guidelines. ESBL-producing E. coli was found in 40 (40%) of the 100 pregnant women, while the proportion of ESBL-producing E. coli was 57.7% among the total E. coli-induced bloodstream infections. ESBL-producing E. coli was isolated from 161 (67.1%) out of 240 broilers. On the other hand, the average concentration of E. coli in the water samples was 2.0 × 108 CFU/100 mL, and the ratio of ESBL-producing E. coli was 12.8% of total E. coli. Unfortunate...
Water is a primary need of the community which is very important, especially to be consumed as dr... more Water is a primary need of the community which is very important, especially to be consumed as drinking water. The amount of drinking water needed by the community continues to increase in line with population growth. The rapidly increasing population is in fact not offset by the availability of enough clean water for drinking. Currently drinking water is used for consumption of various types. Most high economic communities consume Bottled Drinking Water (AMDK) because it is more practical and is considered to be more hygienic. While others choose to consume Refill Drinking Water (AMIU) produced by the Refill Drinking Water Depot (DAMIU) as an alternative because it is more economical. In recent years the development of mineral refill drinking water depots and RO (Reverse Osmosis) businesses has mushroomed. The quality of water that is ready to be offered to the community is sufficiently maintained because the water is supplied directly from mountain springs which depend on the refi...
Kasus foodborne diseases di dunia mencapai sampai 250 kasus yang berbeda dan didominasi oleh peny... more Kasus foodborne diseases di dunia mencapai sampai 250 kasus yang berbeda dan didominasi oleh penyakit infeksi. Foodborne diseases merupakan penyakit yang biasanya bersifat infeksi atau racun yang diakibatkan oleh sumber infeksi yang masuk ke dalam tubuh bersama makanan yang dicerna. Makanan menjadi media penularan penyakit yang baik dalam menghantarkan mikroorganisme patogen sampai ke tempat kolonisasi di dalam tubuh. Foodborne diseases menjadi penyebab morbiditas dan mortalitas yang penting dan mendapat perhatian serius di negara berkembang maupun negara maju. Tulisan ini merupakan studi literatur dengan mengumpulkan data dari hasil penelusuran berbagai sumber seperti jurnal ilmiah, laporan penelitian maupun media online. Gejala foodborne diseases antara lain sakit pada saluran gastrointestinal, neurological, gynaecological, immunological dan gejala lain. Selain itu juga dapat mengakibatkan kegagalan berbagai organ, kanker sampai kematian. Foodborne diseases dibedakan menjadi yaitu...
Prosiding Seminar Nasional Masyarakat Biodiversitas Indonesia, 2019
Abstract. Khariri, Muna F. 2019. The proportion of parasite species that are the cause of malaria... more Abstract. Khariri, Muna F. 2019. The proportion of parasite species that are the cause of malaria infection in Indonesia base on result of Basic Health Research (Riskesdas). Pros Sem Nas Masy Biodiv Indon 5: 38-41. Indonesia has a global Millennium Development Goals (MDGs) commitment to eradicate malaria. Malaria is one of the reemerging diseases in recent years which is marked by an increasing trend in cases in Indonesia. Although Plasmodium has many types, there are only 5 types that can cause Malaria. Malaria laboratory diagnosis can provide information on the type of parasite that causes infection. One of the laboratory examination techniques can be done with Rapid Dianostic Test (RDT). Analysis was carried out on data from the Basic Health Research Results (Riskesdas) 2010 and 2013 in Indonesia. The data obtained were analyzed descriptively. Based on the results of the RDT examination, in Riskesdas 2013 was found that the proportion of the population with positive malaria was 1...
IOP Conference Series: Earth and Environmental Science
Diarrheal diseases are the second cause of the high morbidity and mortality in children under fiv... more Diarrheal diseases are the second cause of the high morbidity and mortality in children under five years old. According to the Basic Health Survey 2018 conducted by the Ministry of Health, the prevalence of diarrheal diseases among children under five years old that were diagnosed by healthcare workers was 11.0%. The aim of this study was to describe the enteric pathogen isolated from children with diarrhea. The study was conducted in five cities in Indonesia: Jakarta, Serang, Denpasar, Makassar, and Mataram. The Inclusion criteria were children aged one month to five years old, with diarrhea that was diagnosed by a healthcare worker. The rectal swabs were sent to the Centre for Research and Development for Biomedical and Basic Health Technology, National Institute of Health Research and Development, Ministry of Health in Jakarta. Virus and Enterotoxigenic Escherichia coli (ETEC) identification by using multiplex PCR from Seegene, meanwhile bacteria identified by conventional method...