funmilayo adewumi - Academia.edu (original) (raw)
Papers by funmilayo adewumi
Open Access Macedonian Journal of Medical Sciences
BACKGROUND: The third identified severe respiratory disease in the past two decades and the first... more BACKGROUND: The third identified severe respiratory disease in the past two decades and the first to result in a pandemic is the coronavirus disease 2019 (COVID-19) specifically caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). AIM: The aim of this study was to provide an overview of the basic pathology and diagnostic laboratory features of COVID-19. METHODS: This review involved search of literatures on PubMed, Science alert, Medline, and Advanced Google search using the keywords “SARS-CoV2,” “Coronavirus” along with “pathology of COVID-19” and “diagnosis of COVID-19” with related articles pooled, relevant information extracted, and properly referenced. RESULTS: The recommended method of diagnosis is by nucleic acid testing of the viral ribonucleic acid in which real-time reverse-transcription polymerase chain reaction followed by nucleic acid sequencing when required is performed while some serologic techniques developed include enzyme-linked immunosorben...
Open Access Macedonian Journal of Medical Sciences
BACKGROUND: The third identified severe respiratory disease in the past two decades and the first... more BACKGROUND: The third identified severe respiratory disease in the past two decades and the first to result in a pandemic is the coronavirus disease 2019 (COVID-19) specifically caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). AIM: The aim of this study was to provide an overview of the basic pathology and diagnostic laboratory features of COVID-19. METHODS: This review involved search of literatures on PubMed, Science alert, Medline, and Advanced Google search using the keywords “SARS-CoV2,” “Coronavirus” along with “pathology of COVID-19” and “diagnosis of COVID-19” with related articles pooled, relevant information extracted, and properly referenced. RESULTS: The recommended method of diagnosis is by nucleic acid testing of the viral ribonucleic acid in which real-time reverse-transcription polymerase chain reaction followed by nucleic acid sequencing when required is performed while some serologic techniques developed include enzyme-linked immunosorben...
Production of extended-spectrum í µí»½-lactamases (ESBLs) producing E. coli in animals and differ... more Production of extended-spectrum í µí»½-lactamases (ESBLs) producing E. coli in animals and different methods of identifications from Ado Ekiti, Ekiti State, Nigeria, were investigated. Three hundred and fifty fecal samples, collected from apparently healthy cattle and pigs, were cultured and identified following standard procedures. ESBL phenotypic detection was carried out using combination disc test, double disc synergism test, and ESBL brilliance agar screening. Molecular detection of TEM, SHV, and CTX-M genes was carried out using standard molecular method. One hundred and fourteen E. coli isolates were recovered from the 350 samples processed, out of which 72 (63.2%) isolates were positive for ESBLs with multiple resistance to the antibiotics used. Eighty-one (71%) isolates were positive for ESBL by combination disc test, 90 (78.9%) were positive for double disc synergism test, and 93 (81.6%) were positive for ESBL brilliance agar. TEM and CTX-M genes were detected in 48 (42.1%) and 51 (44.7%) isolates, respectively. SHV gene was not detected in any of the isolates while TEM and CTX-M were detected in 33 (28.9%) isolates. This study showed high resistance of E. coli to antibiotics, particularly to the third generation cephalosporins. Regular monitoring and regulated use of antibiotics in livestock should be encouraged.
Open Access Macedonian Journal of Medical Sciences
BACKGROUND: The third identified severe respiratory disease in the past two decades and the first... more BACKGROUND: The third identified severe respiratory disease in the past two decades and the first to result in a pandemic is the coronavirus disease 2019 (COVID-19) specifically caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). AIM: The aim of this study was to provide an overview of the basic pathology and diagnostic laboratory features of COVID-19. METHODS: This review involved search of literatures on PubMed, Science alert, Medline, and Advanced Google search using the keywords “SARS-CoV2,” “Coronavirus” along with “pathology of COVID-19” and “diagnosis of COVID-19” with related articles pooled, relevant information extracted, and properly referenced. RESULTS: The recommended method of diagnosis is by nucleic acid testing of the viral ribonucleic acid in which real-time reverse-transcription polymerase chain reaction followed by nucleic acid sequencing when required is performed while some serologic techniques developed include enzyme-linked immunosorben...
Open Access Macedonian Journal of Medical Sciences
BACKGROUND: The third identified severe respiratory disease in the past two decades and the first... more BACKGROUND: The third identified severe respiratory disease in the past two decades and the first to result in a pandemic is the coronavirus disease 2019 (COVID-19) specifically caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). AIM: The aim of this study was to provide an overview of the basic pathology and diagnostic laboratory features of COVID-19. METHODS: This review involved search of literatures on PubMed, Science alert, Medline, and Advanced Google search using the keywords “SARS-CoV2,” “Coronavirus” along with “pathology of COVID-19” and “diagnosis of COVID-19” with related articles pooled, relevant information extracted, and properly referenced. RESULTS: The recommended method of diagnosis is by nucleic acid testing of the viral ribonucleic acid in which real-time reverse-transcription polymerase chain reaction followed by nucleic acid sequencing when required is performed while some serologic techniques developed include enzyme-linked immunosorben...
Production of extended-spectrum í µí»½-lactamases (ESBLs) producing E. coli in animals and differ... more Production of extended-spectrum í µí»½-lactamases (ESBLs) producing E. coli in animals and different methods of identifications from Ado Ekiti, Ekiti State, Nigeria, were investigated. Three hundred and fifty fecal samples, collected from apparently healthy cattle and pigs, were cultured and identified following standard procedures. ESBL phenotypic detection was carried out using combination disc test, double disc synergism test, and ESBL brilliance agar screening. Molecular detection of TEM, SHV, and CTX-M genes was carried out using standard molecular method. One hundred and fourteen E. coli isolates were recovered from the 350 samples processed, out of which 72 (63.2%) isolates were positive for ESBLs with multiple resistance to the antibiotics used. Eighty-one (71%) isolates were positive for ESBL by combination disc test, 90 (78.9%) were positive for double disc synergism test, and 93 (81.6%) were positive for ESBL brilliance agar. TEM and CTX-M genes were detected in 48 (42.1%) and 51 (44.7%) isolates, respectively. SHV gene was not detected in any of the isolates while TEM and CTX-M were detected in 33 (28.9%) isolates. This study showed high resistance of E. coli to antibiotics, particularly to the third generation cephalosporins. Regular monitoring and regulated use of antibiotics in livestock should be encouraged.