gautam kumar - Academia.edu (original) (raw)
Books by gautam kumar
Here the research is about the power system engineering .How the power demand is being utelised b... more Here the research is about the power system engineering .How the power demand is being utelised by the public.So at the peak utilization of the power the elctricity bill increses after the fixed price ...And also the customer is penalised.So the all the techniques are in this paper to know thw power demand and the regulations.
Papers by gautam kumar
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017
To evaluate the safety and efficacy of catheter-directed thrombolysis (CDT) in the treatment of a... more To evaluate the safety and efficacy of catheter-directed thrombolysis (CDT) in the treatment of acute pulmonary embolism (PE). The use of CDT for the treatment of acute submassive and massive PE is increasing in frequency. However, its safety and efficacy have not been well elucidated. This study is made of two parts: one is a two-center registry of acute PE patients treated with CDT. The safety outcome evaluated was any major complication including fatal, intracranial (ICH), intraocular, or retroperitoneal hemorrhage or any overt bleeding requiring transfusion or surgical repair. The efficacy outcome was acute change in invasive pulmonary artery systolic pressure (PASP). The second part is a meta-analysis of all contemporary studies that used CDT for PE. Reported outcomes are the same as in the registry, with the addition of right ventricular to left ventricular (RV/LV) ratio change. In the registry, 137 patients were included (age 59 ± 15, 50% male, 88% submassive PE). ICH occurre...
Journal of the American College of Cardiology, 2016
Journal of the American College of Cardiology, 2016
Journal of the American College of Cardiology, 2016
Proceedings of the Acm Sigcomm 2012 Conference on Applications Technologies Architectures and Protocols For Computer Communication, Aug 13, 2012
ABSTRACT The network is a crucial resource in cloud computing, but in contrast to other resources... more ABSTRACT The network is a crucial resource in cloud computing, but in contrast to other resources such as CPU or memory, the network is currently shared in a best effort manner. However, sharing the network in a datacenter is more challenging than sharing the other ...
Aids, May 23, 2015
Of 6648 female sex workers (FSW) in 13 districts of Andhra Pradesh state in India, only 7.9% repo... more Of 6648 female sex workers (FSW) in 13 districts of Andhra Pradesh state in India, only 7.9% reported having undergone HIV testing, and three-quarters of the rest were unwilling to undergo HIV testing in the future. The risk of HIV infection as a result of the non-use of condoms was higher among FSW who reported not having been tested and were also unwilling to get tested, and they also held significantly more negative beliefs about HIV/AIDS.
International Journal of Cardiology, Oct 29, 2010
Circulation, Oct 31, 2007
Study of Infectious and Non Infectious Problems in Adolescents of Urban City, Jul 31, 2014
Annals of Emergency Medicine, Mar 1, 2007
Http Dx Doi Org 10 4161 Psb 4 5 8298, May 1, 2009
Response of plants towards salinity is multigenic in nature with its various components playing d... more Response of plants towards salinity is multigenic in nature with its various components playing diverse roles in stress perception, relay or response. For the purpose of dissecting the genetic determinants of salinity response in crops, the family Brassicaceae presents an excellent model since significant interand intra-specific variations have been reported for salinity tolerance. Using these intraspecific variations of Brassica, we show that one of the possible mechanism by which a genotype is able to exhibit tolerance better than another is by keeping the basal levels of stress responsive transcripts higher than the sensitive genotype. This is quite reflected when we analyze members of a specific pathway such as SOS pathway or even when we extend the analysis to a range of molecules including those playing important role in stress perception, signal transduction or stress response. However, these investigations need to be extended to genome level transcript analysis to further validate the hypothesis of "well preparedness" in tolerant genotypes and we propose the suitability of Brassica genotypes for this endevours.
In this paper, we propose a novelty-based metric for quantitative characterization of the control... more In this paper, we propose a novelty-based metric for quantitative characterization of the controllability of complex networks. This inherently bounded metric describes the average angular separation of an input with respect to the past input history. We use this metric to find the minimally novel input that drives a linear network to a desired state using unit average energy. Specifically, the minimally novel input is defined as the solution of a continuous time, non-convex optimal control problem based on the introduced metric. We provide conditions for existence and uniqueness, and an explicit, closedform expression for the solution. We support our theoretical results by characterizing the minimally novel inputs for an example of a recurrent neuronal network.
The Journal of Heart Valve Disease, 2015
Transcatheter aortic valve replacements (TAVRs) are performed using fluoroscopic guidance, which ... more Transcatheter aortic valve replacements (TAVRs) are performed using fluoroscopic guidance, which makes precise positioning challenging. The aim of the present study was to investigate the effect of TAV positioning on flow characteristics in the ascending aorta and sinuses. A commonly used TAV design with a supra-annular support section was investigated using particle image velocimetry (PIV) under physiological flow and pressure conditions. A bioprosthetic valve served as a control and mimicked the native aortic valve. The valve assembly was mounted in a custom-designed chamber with an axisymmetric sinus, the design of which was based on anatomic dimensions. The TAV was deployed in the supra-annular (high) and sub- annular (low) implantation positions and studied at two cardiac outputs (5.0 and 2.5 l/min). The TAV showed good systolic flow characteristics with wide forward flow jets in the ascending aorta (V = 1.5 m/s at 5.0 1/min; V = 1.0 m/s at 2.5 1/min). In the high implantation, the physical spacing between the leaflet free edge and sinotubular junction was reduced (< 10 mm), causing a weaker sinus vortex and a lower washout. A larger region of low velocity (< 0.1 m/s) in the sinus was observed at high implantation at all time points, particularly at a cardiac output of 2.5 l/min. In the low implantation, good sinus washout was observed. For optimal sinus washout, sub- annular TAV deployment is recommended, particularly for patients with smaller sinuses. An impaired cardiac output may also require sub- annular deployment for adequate sinus washout. The study results confirmed the need for precise TAV deployment tailored to patient-specific annular and sinus dimensions, as sub-optimal positioning may inhibit coronary perfusion and cause potential regions of stasis near the aortic annulus.
Proceedings of the 2010 American Control Conference, 2010
We propose to use the Izhikevich single neuron model to represent a motor cortex neuron for study... more We propose to use the Izhikevich single neuron model to represent a motor cortex neuron for studying a control-theoretic perspective of a neuroprosthetic system. The problem of estimating model parameters is addressed when the only available data from intracortical recordings of a neuron are the Inter-Spike Intervals (ISIs). Non-linear constrained and unconstrained optimization problems are formulated to estimate model parameters as well as synaptic inputs using ISIs data. The primal-dual interior-point method is implemented to solve the constrained optimization problem. Reasonable model parameters are estimated by solving these optimization problems which may serve as a template for studying and developing a model of ensemble cortical neurons for neuroprosthesis applications.
The American Journal of Cardiology, 2015
Warm temperatures induce peripheral vasodilation, decrease afterload, and may concurrently increa... more Warm temperatures induce peripheral vasodilation, decrease afterload, and may concurrently increase the left ventricular outflow tract (LVOT) gradient. We aimed to assess the impact of subjective ambient temperature on hypertrophic cardiomyopathy (HC) symptoms and determine whether they were associated with LVOT gradient, patient quality of life (QOL), and risk of sudden cardiac death (SCD). We identified consecutive patients with HC presenting to a tertiary referral center. Of the 173 patients in the study, 143 (83%) had HC symptoms, with ambient temperature change worsening symptoms for 72 patients (50%). Symptom exacerbation occurred only with heat for 57 (79%), whereas symptoms were exacerbated with cold only or with cold and heat equally for 15 (21%). Patients affected by any temperature exacerbation more commonly were women (p = 0.009), had a lower QOL (p = 0.04), had a family history of HC (p = 0.007), or underwent myectomy (p = 0.01). A greater proportion of patients with heat-only exacerbation had a family history of HC (p = 0.005) and SCD (p = 0.05). The presence of an LVOT gradient either at rest or with provocation was similar in all groups. In conclusion, although no appreciable difference in LVOT gradients were observed between patient groups, approximately half of the patients with HC reporting symptoms at baseline noted worsening of symptoms with temperature changes, with >75% describing heat-induced symptom exacerbation. Furthermore, affected patients more frequently were women, underwent surgical intervention and device implantation, and had an overall lower QOL.
Annals of Emergency Medicine, 2007
Here the research is about the power system engineering .How the power demand is being utelised b... more Here the research is about the power system engineering .How the power demand is being utelised by the public.So at the peak utilization of the power the elctricity bill increses after the fixed price ...And also the customer is penalised.So the all the techniques are in this paper to know thw power demand and the regulations.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017
To evaluate the safety and efficacy of catheter-directed thrombolysis (CDT) in the treatment of a... more To evaluate the safety and efficacy of catheter-directed thrombolysis (CDT) in the treatment of acute pulmonary embolism (PE). The use of CDT for the treatment of acute submassive and massive PE is increasing in frequency. However, its safety and efficacy have not been well elucidated. This study is made of two parts: one is a two-center registry of acute PE patients treated with CDT. The safety outcome evaluated was any major complication including fatal, intracranial (ICH), intraocular, or retroperitoneal hemorrhage or any overt bleeding requiring transfusion or surgical repair. The efficacy outcome was acute change in invasive pulmonary artery systolic pressure (PASP). The second part is a meta-analysis of all contemporary studies that used CDT for PE. Reported outcomes are the same as in the registry, with the addition of right ventricular to left ventricular (RV/LV) ratio change. In the registry, 137 patients were included (age 59 ± 15, 50% male, 88% submassive PE). ICH occurre...
Journal of the American College of Cardiology, 2016
Journal of the American College of Cardiology, 2016
Journal of the American College of Cardiology, 2016
Proceedings of the Acm Sigcomm 2012 Conference on Applications Technologies Architectures and Protocols For Computer Communication, Aug 13, 2012
ABSTRACT The network is a crucial resource in cloud computing, but in contrast to other resources... more ABSTRACT The network is a crucial resource in cloud computing, but in contrast to other resources such as CPU or memory, the network is currently shared in a best effort manner. However, sharing the network in a datacenter is more challenging than sharing the other ...
Aids, May 23, 2015
Of 6648 female sex workers (FSW) in 13 districts of Andhra Pradesh state in India, only 7.9% repo... more Of 6648 female sex workers (FSW) in 13 districts of Andhra Pradesh state in India, only 7.9% reported having undergone HIV testing, and three-quarters of the rest were unwilling to undergo HIV testing in the future. The risk of HIV infection as a result of the non-use of condoms was higher among FSW who reported not having been tested and were also unwilling to get tested, and they also held significantly more negative beliefs about HIV/AIDS.
International Journal of Cardiology, Oct 29, 2010
Circulation, Oct 31, 2007
Study of Infectious and Non Infectious Problems in Adolescents of Urban City, Jul 31, 2014
Annals of Emergency Medicine, Mar 1, 2007
Http Dx Doi Org 10 4161 Psb 4 5 8298, May 1, 2009
Response of plants towards salinity is multigenic in nature with its various components playing d... more Response of plants towards salinity is multigenic in nature with its various components playing diverse roles in stress perception, relay or response. For the purpose of dissecting the genetic determinants of salinity response in crops, the family Brassicaceae presents an excellent model since significant interand intra-specific variations have been reported for salinity tolerance. Using these intraspecific variations of Brassica, we show that one of the possible mechanism by which a genotype is able to exhibit tolerance better than another is by keeping the basal levels of stress responsive transcripts higher than the sensitive genotype. This is quite reflected when we analyze members of a specific pathway such as SOS pathway or even when we extend the analysis to a range of molecules including those playing important role in stress perception, signal transduction or stress response. However, these investigations need to be extended to genome level transcript analysis to further validate the hypothesis of "well preparedness" in tolerant genotypes and we propose the suitability of Brassica genotypes for this endevours.
In this paper, we propose a novelty-based metric for quantitative characterization of the control... more In this paper, we propose a novelty-based metric for quantitative characterization of the controllability of complex networks. This inherently bounded metric describes the average angular separation of an input with respect to the past input history. We use this metric to find the minimally novel input that drives a linear network to a desired state using unit average energy. Specifically, the minimally novel input is defined as the solution of a continuous time, non-convex optimal control problem based on the introduced metric. We provide conditions for existence and uniqueness, and an explicit, closedform expression for the solution. We support our theoretical results by characterizing the minimally novel inputs for an example of a recurrent neuronal network.
The Journal of Heart Valve Disease, 2015
Transcatheter aortic valve replacements (TAVRs) are performed using fluoroscopic guidance, which ... more Transcatheter aortic valve replacements (TAVRs) are performed using fluoroscopic guidance, which makes precise positioning challenging. The aim of the present study was to investigate the effect of TAV positioning on flow characteristics in the ascending aorta and sinuses. A commonly used TAV design with a supra-annular support section was investigated using particle image velocimetry (PIV) under physiological flow and pressure conditions. A bioprosthetic valve served as a control and mimicked the native aortic valve. The valve assembly was mounted in a custom-designed chamber with an axisymmetric sinus, the design of which was based on anatomic dimensions. The TAV was deployed in the supra-annular (high) and sub- annular (low) implantation positions and studied at two cardiac outputs (5.0 and 2.5 l/min). The TAV showed good systolic flow characteristics with wide forward flow jets in the ascending aorta (V = 1.5 m/s at 5.0 1/min; V = 1.0 m/s at 2.5 1/min). In the high implantation, the physical spacing between the leaflet free edge and sinotubular junction was reduced (< 10 mm), causing a weaker sinus vortex and a lower washout. A larger region of low velocity (< 0.1 m/s) in the sinus was observed at high implantation at all time points, particularly at a cardiac output of 2.5 l/min. In the low implantation, good sinus washout was observed. For optimal sinus washout, sub- annular TAV deployment is recommended, particularly for patients with smaller sinuses. An impaired cardiac output may also require sub- annular deployment for adequate sinus washout. The study results confirmed the need for precise TAV deployment tailored to patient-specific annular and sinus dimensions, as sub-optimal positioning may inhibit coronary perfusion and cause potential regions of stasis near the aortic annulus.
Proceedings of the 2010 American Control Conference, 2010
We propose to use the Izhikevich single neuron model to represent a motor cortex neuron for study... more We propose to use the Izhikevich single neuron model to represent a motor cortex neuron for studying a control-theoretic perspective of a neuroprosthetic system. The problem of estimating model parameters is addressed when the only available data from intracortical recordings of a neuron are the Inter-Spike Intervals (ISIs). Non-linear constrained and unconstrained optimization problems are formulated to estimate model parameters as well as synaptic inputs using ISIs data. The primal-dual interior-point method is implemented to solve the constrained optimization problem. Reasonable model parameters are estimated by solving these optimization problems which may serve as a template for studying and developing a model of ensemble cortical neurons for neuroprosthesis applications.
The American Journal of Cardiology, 2015
Warm temperatures induce peripheral vasodilation, decrease afterload, and may concurrently increa... more Warm temperatures induce peripheral vasodilation, decrease afterload, and may concurrently increase the left ventricular outflow tract (LVOT) gradient. We aimed to assess the impact of subjective ambient temperature on hypertrophic cardiomyopathy (HC) symptoms and determine whether they were associated with LVOT gradient, patient quality of life (QOL), and risk of sudden cardiac death (SCD). We identified consecutive patients with HC presenting to a tertiary referral center. Of the 173 patients in the study, 143 (83%) had HC symptoms, with ambient temperature change worsening symptoms for 72 patients (50%). Symptom exacerbation occurred only with heat for 57 (79%), whereas symptoms were exacerbated with cold only or with cold and heat equally for 15 (21%). Patients affected by any temperature exacerbation more commonly were women (p = 0.009), had a lower QOL (p = 0.04), had a family history of HC (p = 0.007), or underwent myectomy (p = 0.01). A greater proportion of patients with heat-only exacerbation had a family history of HC (p = 0.005) and SCD (p = 0.05). The presence of an LVOT gradient either at rest or with provocation was similar in all groups. In conclusion, although no appreciable difference in LVOT gradients were observed between patient groups, approximately half of the patients with HC reporting symptoms at baseline noted worsening of symptoms with temperature changes, with >75% describing heat-induced symptom exacerbation. Furthermore, affected patients more frequently were women, underwent surgical intervention and device implantation, and had an overall lower QOL.
Annals of Emergency Medicine, 2007
Mayo Clinic Proceedings, Nov 1, 2010
A 51-year-old man presented to the internal medicine clinic for a Department of Transportation me... more A 51-year-old man presented to the internal medicine clinic for a Department of Transportation medical examination to renew his commercial motor vehicle license. He denied any symptoms at the time of his visit. On detailed questioning, however, the patient reported progressive dyspnea on exertion of several months' duration. These symptoms were not particularly worrisome to the patient because he attributed them to deconditioning.