hasan havıtçıoğlu - Academia.edu (original) (raw)

Papers by hasan havıtçıoğlu

Research paper thumbnail of Kıkırdak doku mühendisliğinde yenilikler

TOTBİD Dergisi

Kıkırdak sinovyal eklemlerde, omurgada, kaburgalarda, dış kulaklarda, burunda ve solunum yolların... more Kıkırdak sinovyal eklemlerde, omurgada, kaburgalarda, dış kulaklarda, burunda ve solunum yollarında, çocukların ve ergenlerin büyüme plakalarında bulunan avasküler, anöral ve alenfatik bir bağ dokusudur. İnsanlarda hiyalin, fibröz ve elastik kıkırdak dokusu olarak üç ana türde mevcuttur. [1] Her üç kıkırdak türü de, hücre dışı matrisin (extra-cellular matrix, ECM) ana bileşenlerini sentezleyen ve salgılayan düşük bir hücre yoğunluğuna (kondrositler) sahiptir. [2,3]

Research paper thumbnail of Three-Dimensionally-Printed Joint-Preserving Prosthetic Reconstruction of Massive Bone Defects After Malignant Tumor Resection of the Proximal Tibia

Cureus, 2021

Joint-preserving prosthetic reconstruction for massive bone defects has the potential to be a new... more Joint-preserving prosthetic reconstruction for massive bone defects has the potential to be a new and revolutionary treatment option. In this paper, we discuss the case of a 30-year-old female patient who presented with pain and swelling around the knee for three months. The patient underwent this procedure. Postoperative patient satisfaction, pain scores, and range of motion results were found to be promising. We believe that this method has the potential to be the next stage in the quest for better treatment options for this condition.

Research paper thumbnail of Benign Kemik Tümörleri

Turkiye Klinikleri Journal of Surgical Medical Sciences, 2006

Research paper thumbnail of Periferik Sinir Dokusunun Biyomekanik Özellikleri

Acta Orthopaedica Et Traumatologica Turcica, Oct 23, 2007

Research paper thumbnail of Mechanical Comparison of Headless Screw Fixation and Locking Plate Fixation for Talar Neck Fractures

The Journal of Foot and Ankle Surgery, 2015

Research paper thumbnail of Acta-İbrahi̇m Mutlu (2)

Research paper thumbnail of Osteoblast hücre kültürlerinin ses dalgaları ile mekanik uyarımı

acta orthopaedica et traumatologica turcica

Research paper thumbnail of Rigid fixation of the lumbar spine alters the motion and mechanical stability at the adjacent segment level

Joint Diseases and Related Surgery, 2014

Bu çalışmada lomber omurganın rijit tespitinden sonra komşu segmentin hareket genişliği ve stabil... more Bu çalışmada lomber omurganın rijit tespitinden sonra komşu segmentin hareket genişliği ve stabilitesi araştırıldı. Gereç ve yöntemler: Bu çalışmada 17 taze donmuş kuzu lomber omurgası (sakrum T 12 'yi içeren) kullanıldı. Biyomekanik test aksiyel kompresyon test cihazı ile yapıldı. Aksiyel kompresyon tüm numunelere 5 mm/dk. yükleme hızı ile uygulandı. Özel dizayn edilmiş fikstür ile 8400 Nmm tork oluşturuldu. Fikstür aksiyel yönde fleksiyon, ekstansiyon, sağ ve sola eğilme pozisyonlarında yüklenme uygulanacak şekilde numuneler ayarlandı. Tüm numuneler sağlam omurga, pedikül vida ve rod fiksasyonu sonrasında teste tabi tutuldu. Test esnasında komşu seviye L5-S1 arasındaki ayrılma değerleri süreğen bir şekilde ekstansometre ile kaydedildi. Bulgular: Komşu segmentte (L5-S1), aksiyel yüklenme ve üst-alt ayrılma değerleri, ön-arka ayrılma değerlerinden düşük bulundu. İstatistiksel analizde sağlam omurga ile komşu segment arasında aksiyel kompresyon ve ekstansiyon pozisyonunda sayısal anlamlı değişiklikler tespit edildi (p<0.027). Bunun yanında ekstansiyon pozisyonunda komşu segmentte sağlam omurgaya göre daha yüksek çıktı (p<0.015). Sonuç: Lomber omurganın rijit fiksasyonu komşu segment seviyesinde hareket genişliğini değiştirmektedir. Bundan dolayı, komşu segmentte anormal stres ve spinal instabiliteye neden olur; bu durum, faset eklem dejenerasyonuna ve bel ağrılarına yol açabilir. Anahtar sözcükler: Komşu segment instabilitesi; faset eklem; omurlar arası disk; lomber omurga. Objectives: This study aims to examine the motion and stability of the adjacent segment following rigid fixation of the lumbar spine. Materials and methods: The study included 17 fresh-frozen lamb lumbar spines (including the sacrum to T 12). Biomechanical testing was performed using an axial compression testing machine. Axial compression was applied to all the specimens using a loading speed of 5 mm min-1. A specifically designed fixture was used to generate torque ≤8400 Nmm. The fixture was used with each specimen to achieve flexion and extension, axial neutral compression, and right and left bending. All specimens were tested intact, and again after implantation using posterior pedicle screws and rod fixation. During testing intervertebral displacement at the adjacent level (L5-S1) was recorded continuously via extensometry. Results: Axial compression and superior-inferior displacement were lower in the adjacent segment (L5-S1) than anterior-posterior displacement following rigid fixation. Statistical analysis showed that there was a numerical difference and a significant change between the intact spine and the adjacent segment in the axial compression and extension positions (p<0.027). The intact spines demonstrated the maximum displacement and the difference in extension positions were significant (p<0.015). Conclusion: Rigid fixation of the lumbar spine altered the range of motion at the adjacent segment level. As such, abnormal stress on the adjacent segment causes spinal instability, which may subsequently cause facet joint degeneration and low back pain.

Research paper thumbnail of Newly diagnosed diabetic patient presenting with crural infection

Endocrine Abstracts, 2013

Research paper thumbnail of Predictors of amputation in diabetics with foot ulcer: Single center experience in a large Turkish cohort

HORMONES, 2009

OBJECTIVE: Prediction of diabetic foot ulcer outcome may be helpful for clinicians in optimizing ... more OBJECTIVE: Prediction of diabetic foot ulcer outcome may be helpful for clinicians in optimizing and individualizing management strategy. The aim of the present study was to examine the possibility of predicting the outcome of patients with diabetic foot ulcers by using easily assessed clinical and laboratory parameters at baseline. DESIGN: In this observational study, data were collected prospectively in 670 consecutive diabetic foot ulcer episodes in 510 patients examined between January 1999 and June 2008 and were used to evaluate potential predictors of amputation retrospectively. After exclusion of patients who did not come to the hospital for follow-up for a minimum of six months, data of 574 foot ulcer episodes were evaluated. RESULTS: Limb ischemia, osteomyelitis and presence of gangrene and ulcer depth, determined by the Wagner classification system, were the major independent predictors of overall and major amputations. Older age, presence of coronary artery disease, smoking and ulcer size were found to be associated with either overall or major amputations. Baseline levels of acute phase reactants (white blood cell count, polymorphonuclear leukocyte count, platelet count, erythrocyte sedimentation rate (ESR), serum C-reactive protein (CRP) and albumin) and decreased hemoglobin levels were associated with amputation risk. Multivariate analysis showed that one standard deviation increase in baseline CRP and ESR levels were independent predictors of overall and major amputations, respectively. CONCLUSIONS: The presence of limb ischemia, osteomyelitis, local and diffuse gangrene and ulcer depth were independent predictors of amputation. Baseline levels of ESR and CRP appeared to be helpful for clinicians in predicting amputation.

Research paper thumbnail of Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma: characterization of five cases

Skeletal Radiology, 2013

Aim: Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma is a rare local aggressive va... more Aim: Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma is a rare local aggressive vascular tumor. Herein we present a 54-year-old male patient with a tumor on his index finger. Case: The patient presented with a 1-year history of pain and swelling that progressively exacerbated. Bone invasion was observed on the middle phalanx via direct radiography. Histopathological examination findings were compatible with epithelioid sarcoma-like hemangioendothelioma. Conclusion: To the best of our knowledge is the first case report of epithelioid sarcoma-like hemangioendothelioma with bone invasion.

Research paper thumbnail of Bilateral congenital subluxation of the proximal tibiofibular joint with magnetic resonance imaging findings: a case report

Knee Surgery, Sports Traumatology, Arthroscopy, 2002

Research paper thumbnail of Strength of Different Krackow Stitch Configurations Using High-strength Suture

The Journal of Foot and Ankle Surgery, 2013

The purpose of the present study concerning high-strength sutures was to determine whether increa... more The purpose of the present study concerning high-strength sutures was to determine whether increasing the number of locking loops with different size sutures or decreasing the suture size with increased suture strands would have any influence on the strength of Achilles tendon repair. A total of 32 fresh bovine Achilles tendon specimens were randomly assigned to 4 groups. For 3 of the groups, 1 suture was used (no. 2 or no. 5 FiberWire™ with 2 or 4 Krackow locking loops). For the fourth group, 2 sutures (2-0 FiberWire™) with 2 locking loops were used. After repair, the study groups underwent cyclic loading (0 to 200 N, 200 cycles) and then underwent tension to failure in a testing machine. Cyclic elongation, peak to peak displacement, ultimate load, stiffness, and failure mode were recorded for each specimen. The tendon width and thickness were measured in all specimens. The mean width, thickness, cyclic displacement, load to failure, and pull-out stiffness showed no differences among the 4 groups. The cyclic peak to peak displacements (0.01 ± 0.01 mm) were smallest with the no. 5 suture with 4 locking loops (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .05), with no failure during cyclic loading, unlike in the other groups. In the group with 2-0 suture with 4 strands and 2 locking loops, 6 failed during cyclic loading. The number of locking loops used might have had an influence on the strength of the Krackow suture configuration using the larger diameter, high-strength sutures. However, decreasing the suture diameter, with a simultaneous increase in the number of strands, failed to improve the initial strength of the repair.

Research paper thumbnail of Comparison between a standard intramedullary nail and self-guided multiple cannulated intramedullary nail

Journal of Biomechanics, 2011

Research paper thumbnail of A new method to measure vertebral rotation from CT scans

European Spine Journal, 1999

Research paper thumbnail of Calcium Pyrophosphate Dihydrate Crystal Deposition Disease: Nomenclature and Diagnostic Criteria

Annals of Internal Medicine, 1977

Excerpt The variety of names suggested for the condition associated with deposits of calcium pyro... more Excerpt The variety of names suggested for the condition associated with deposits of calcium pyrophosphate dihydrate crystals is exceeded only by the variations of its clinical presentation. "Artic...

Research paper thumbnail of In vivo investigation of calcium phosphate coatings on Ti6-Al-4V alloy substrates using lactic acid - sodium lactate buffered synthetic body fluid

Acta Orthopaedica et Traumatologica Turcica, 2013

The aim of this study was to evaluate the mode of failure and biomechanical characteristics of Ti... more The aim of this study was to evaluate the mode of failure and biomechanical characteristics of Ti-6Al-4V anchors biomimetically coated with calcium phosphate (CaP) for soft tissue fixation to bone in an animal model. The current study included 14 adult New Zealand white rabbits equally divided into two groups. Calcium phosphate-coated Ti-6Al-4V anchors were used in the test group and non-coated Ti-6Al-4V anchors in the control group. A new approach was applied to synthesize the CaP coatings via the biomimetic growth in the Lac-SBF containing Ca(2+) and PO4(3-) ions, Na-lactate and lactic acid (HL). Titanium anchors were implanted into the right tibia, followed by biomechanical tensile strength tests. Histological studies were carried out after removal of anchors (bone-implant surface). The CaP-coated Ti-6Al-4V anchors had significantly higher tensile strength (p=0.003) and displacement values (p=0.004) than the non-coated anchors. Control group scores were higher than those of the test group (14 and 9, respectively) in tensile strength tests. The new CaP coating can be used in orthopedic surgery as catalyzer to improve bone ingrowth. We believe that our research will form a model for further research on biomimetic coatings on Ti-6Al-4V substrates.

Research paper thumbnail of Aneurysmal bone cyst healing response with intramedullary lengthening nail

Acta Orthopaedica et Traumatologica Turcica, 2017

We report the treatment process of a pediatric patient with deformity and shortening in the arm a... more We report the treatment process of a pediatric patient with deformity and shortening in the arm after a recurrent aggressive aneurysmal bone cyst (ABC) in the proximal humerus. The patient was treated with curettage of the lesion and lengthening on an intramedullary nail following an osteotomy just distal to the ABC. The period of lengthening was approximately 50 days. At the end of the treatment the lengthening goal was achieved without any neurovascular complication. There was a minimal loss in shoulder hyperabduction due to the deformity of the humeral head.

Research paper thumbnail of Scapular spine base fracture with long outside-in superior or posterior screws with reverse shoulder arthroplasty

Clinics in Shoulder and Elbow

Background: The purpose of the present study was to determine how long superior screws alone or i... more Background: The purpose of the present study was to determine how long superior screws alone or in combination with posterior placement of metaglene screws protruding and penetrating into the scapular spine in reverse total shoulder arthroplasty affect the strength of the scapular spine in a fresh cadaveric scapular model.Methods: Seven fresh cadaver scapulas were allocated to the control group (short posterior and superior screws) and seven scapulas to the study group (spine base fixation with a 4-inch-long superior screw, three with both long superior and long posterior screws).Results: The failure load was lower in the spine fixation group (long screw [869 N] vs. short screw [1,123 N]); however, this difference did not reach statistical significance (p>0.05). All outside-in long superior or superior plus posterior screws failed due to scapular spine base fracture; failures in the short screw group were due to acromion fracture. An additional posterior outside-in screw failed t...

Research paper thumbnail of A review of current developments in three-dimensional scaffolds for medical applications

Turkish Journal of Plastic Surgery, 2021

Humans require treatment due to the loss of tissues after trauma and diseases. Tissue engineering... more Humans require treatment due to the loss of tissues after trauma and diseases. Tissue engineering is a growing field of engineering and medical science to restore, maintain, or improve function of damaged or diseased tissues. The use of three-dimension (3D) scaffolds in particular offers a potential option for patients with tissue deficiency. Polylactic acid (PLA), poly-caprolactone (PCL), polyether-ether-ketone (PEEK), and thermoplastic polyurethane (TPU) are biomaterials that are commonly used in tissue engineering. Their applications of pure material or composite and supportive materials are of great importance for clinical practices. This review provides information on biomaterials and major areas of application and discusses their advantages and disadvantages against each other. The literature search from the database PubMed was done for the key words 3D PLA, PCL, PEEK, and TPU separately and 2029 articles were identified. These articles were limited according to clinical, in vivo and observational studies published in English and 140 articles were evaluated for this review. We selected the main articles according to the current data of 3D scaffolds and identical articles were removed. Fifty articles were included in the review. Many studies have reported the advantages of 3D scaffolds with composite or supplement materials over pure materials in the medical treatment. The advances in the development of new 3D scaffolds hold great promise for the prospective applications in the medical treatment.

Research paper thumbnail of Kıkırdak doku mühendisliğinde yenilikler

TOTBİD Dergisi

Kıkırdak sinovyal eklemlerde, omurgada, kaburgalarda, dış kulaklarda, burunda ve solunum yolların... more Kıkırdak sinovyal eklemlerde, omurgada, kaburgalarda, dış kulaklarda, burunda ve solunum yollarında, çocukların ve ergenlerin büyüme plakalarında bulunan avasküler, anöral ve alenfatik bir bağ dokusudur. İnsanlarda hiyalin, fibröz ve elastik kıkırdak dokusu olarak üç ana türde mevcuttur. [1] Her üç kıkırdak türü de, hücre dışı matrisin (extra-cellular matrix, ECM) ana bileşenlerini sentezleyen ve salgılayan düşük bir hücre yoğunluğuna (kondrositler) sahiptir. [2,3]

Research paper thumbnail of Three-Dimensionally-Printed Joint-Preserving Prosthetic Reconstruction of Massive Bone Defects After Malignant Tumor Resection of the Proximal Tibia

Cureus, 2021

Joint-preserving prosthetic reconstruction for massive bone defects has the potential to be a new... more Joint-preserving prosthetic reconstruction for massive bone defects has the potential to be a new and revolutionary treatment option. In this paper, we discuss the case of a 30-year-old female patient who presented with pain and swelling around the knee for three months. The patient underwent this procedure. Postoperative patient satisfaction, pain scores, and range of motion results were found to be promising. We believe that this method has the potential to be the next stage in the quest for better treatment options for this condition.

Research paper thumbnail of Benign Kemik Tümörleri

Turkiye Klinikleri Journal of Surgical Medical Sciences, 2006

Research paper thumbnail of Periferik Sinir Dokusunun Biyomekanik Özellikleri

Acta Orthopaedica Et Traumatologica Turcica, Oct 23, 2007

Research paper thumbnail of Mechanical Comparison of Headless Screw Fixation and Locking Plate Fixation for Talar Neck Fractures

The Journal of Foot and Ankle Surgery, 2015

Research paper thumbnail of Acta-İbrahi̇m Mutlu (2)

Research paper thumbnail of Osteoblast hücre kültürlerinin ses dalgaları ile mekanik uyarımı

acta orthopaedica et traumatologica turcica

Research paper thumbnail of Rigid fixation of the lumbar spine alters the motion and mechanical stability at the adjacent segment level

Joint Diseases and Related Surgery, 2014

Bu çalışmada lomber omurganın rijit tespitinden sonra komşu segmentin hareket genişliği ve stabil... more Bu çalışmada lomber omurganın rijit tespitinden sonra komşu segmentin hareket genişliği ve stabilitesi araştırıldı. Gereç ve yöntemler: Bu çalışmada 17 taze donmuş kuzu lomber omurgası (sakrum T 12 'yi içeren) kullanıldı. Biyomekanik test aksiyel kompresyon test cihazı ile yapıldı. Aksiyel kompresyon tüm numunelere 5 mm/dk. yükleme hızı ile uygulandı. Özel dizayn edilmiş fikstür ile 8400 Nmm tork oluşturuldu. Fikstür aksiyel yönde fleksiyon, ekstansiyon, sağ ve sola eğilme pozisyonlarında yüklenme uygulanacak şekilde numuneler ayarlandı. Tüm numuneler sağlam omurga, pedikül vida ve rod fiksasyonu sonrasında teste tabi tutuldu. Test esnasında komşu seviye L5-S1 arasındaki ayrılma değerleri süreğen bir şekilde ekstansometre ile kaydedildi. Bulgular: Komşu segmentte (L5-S1), aksiyel yüklenme ve üst-alt ayrılma değerleri, ön-arka ayrılma değerlerinden düşük bulundu. İstatistiksel analizde sağlam omurga ile komşu segment arasında aksiyel kompresyon ve ekstansiyon pozisyonunda sayısal anlamlı değişiklikler tespit edildi (p<0.027). Bunun yanında ekstansiyon pozisyonunda komşu segmentte sağlam omurgaya göre daha yüksek çıktı (p<0.015). Sonuç: Lomber omurganın rijit fiksasyonu komşu segment seviyesinde hareket genişliğini değiştirmektedir. Bundan dolayı, komşu segmentte anormal stres ve spinal instabiliteye neden olur; bu durum, faset eklem dejenerasyonuna ve bel ağrılarına yol açabilir. Anahtar sözcükler: Komşu segment instabilitesi; faset eklem; omurlar arası disk; lomber omurga. Objectives: This study aims to examine the motion and stability of the adjacent segment following rigid fixation of the lumbar spine. Materials and methods: The study included 17 fresh-frozen lamb lumbar spines (including the sacrum to T 12). Biomechanical testing was performed using an axial compression testing machine. Axial compression was applied to all the specimens using a loading speed of 5 mm min-1. A specifically designed fixture was used to generate torque ≤8400 Nmm. The fixture was used with each specimen to achieve flexion and extension, axial neutral compression, and right and left bending. All specimens were tested intact, and again after implantation using posterior pedicle screws and rod fixation. During testing intervertebral displacement at the adjacent level (L5-S1) was recorded continuously via extensometry. Results: Axial compression and superior-inferior displacement were lower in the adjacent segment (L5-S1) than anterior-posterior displacement following rigid fixation. Statistical analysis showed that there was a numerical difference and a significant change between the intact spine and the adjacent segment in the axial compression and extension positions (p<0.027). The intact spines demonstrated the maximum displacement and the difference in extension positions were significant (p<0.015). Conclusion: Rigid fixation of the lumbar spine altered the range of motion at the adjacent segment level. As such, abnormal stress on the adjacent segment causes spinal instability, which may subsequently cause facet joint degeneration and low back pain.

Research paper thumbnail of Newly diagnosed diabetic patient presenting with crural infection

Endocrine Abstracts, 2013

Research paper thumbnail of Predictors of amputation in diabetics with foot ulcer: Single center experience in a large Turkish cohort

HORMONES, 2009

OBJECTIVE: Prediction of diabetic foot ulcer outcome may be helpful for clinicians in optimizing ... more OBJECTIVE: Prediction of diabetic foot ulcer outcome may be helpful for clinicians in optimizing and individualizing management strategy. The aim of the present study was to examine the possibility of predicting the outcome of patients with diabetic foot ulcers by using easily assessed clinical and laboratory parameters at baseline. DESIGN: In this observational study, data were collected prospectively in 670 consecutive diabetic foot ulcer episodes in 510 patients examined between January 1999 and June 2008 and were used to evaluate potential predictors of amputation retrospectively. After exclusion of patients who did not come to the hospital for follow-up for a minimum of six months, data of 574 foot ulcer episodes were evaluated. RESULTS: Limb ischemia, osteomyelitis and presence of gangrene and ulcer depth, determined by the Wagner classification system, were the major independent predictors of overall and major amputations. Older age, presence of coronary artery disease, smoking and ulcer size were found to be associated with either overall or major amputations. Baseline levels of acute phase reactants (white blood cell count, polymorphonuclear leukocyte count, platelet count, erythrocyte sedimentation rate (ESR), serum C-reactive protein (CRP) and albumin) and decreased hemoglobin levels were associated with amputation risk. Multivariate analysis showed that one standard deviation increase in baseline CRP and ESR levels were independent predictors of overall and major amputations, respectively. CONCLUSIONS: The presence of limb ischemia, osteomyelitis, local and diffuse gangrene and ulcer depth were independent predictors of amputation. Baseline levels of ESR and CRP appeared to be helpful for clinicians in predicting amputation.

Research paper thumbnail of Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma: characterization of five cases

Skeletal Radiology, 2013

Aim: Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma is a rare local aggressive va... more Aim: Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma is a rare local aggressive vascular tumor. Herein we present a 54-year-old male patient with a tumor on his index finger. Case: The patient presented with a 1-year history of pain and swelling that progressively exacerbated. Bone invasion was observed on the middle phalanx via direct radiography. Histopathological examination findings were compatible with epithelioid sarcoma-like hemangioendothelioma. Conclusion: To the best of our knowledge is the first case report of epithelioid sarcoma-like hemangioendothelioma with bone invasion.

Research paper thumbnail of Bilateral congenital subluxation of the proximal tibiofibular joint with magnetic resonance imaging findings: a case report

Knee Surgery, Sports Traumatology, Arthroscopy, 2002

Research paper thumbnail of Strength of Different Krackow Stitch Configurations Using High-strength Suture

The Journal of Foot and Ankle Surgery, 2013

The purpose of the present study concerning high-strength sutures was to determine whether increa... more The purpose of the present study concerning high-strength sutures was to determine whether increasing the number of locking loops with different size sutures or decreasing the suture size with increased suture strands would have any influence on the strength of Achilles tendon repair. A total of 32 fresh bovine Achilles tendon specimens were randomly assigned to 4 groups. For 3 of the groups, 1 suture was used (no. 2 or no. 5 FiberWire™ with 2 or 4 Krackow locking loops). For the fourth group, 2 sutures (2-0 FiberWire™) with 2 locking loops were used. After repair, the study groups underwent cyclic loading (0 to 200 N, 200 cycles) and then underwent tension to failure in a testing machine. Cyclic elongation, peak to peak displacement, ultimate load, stiffness, and failure mode were recorded for each specimen. The tendon width and thickness were measured in all specimens. The mean width, thickness, cyclic displacement, load to failure, and pull-out stiffness showed no differences among the 4 groups. The cyclic peak to peak displacements (0.01 ± 0.01 mm) were smallest with the no. 5 suture with 4 locking loops (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .05), with no failure during cyclic loading, unlike in the other groups. In the group with 2-0 suture with 4 strands and 2 locking loops, 6 failed during cyclic loading. The number of locking loops used might have had an influence on the strength of the Krackow suture configuration using the larger diameter, high-strength sutures. However, decreasing the suture diameter, with a simultaneous increase in the number of strands, failed to improve the initial strength of the repair.

Research paper thumbnail of Comparison between a standard intramedullary nail and self-guided multiple cannulated intramedullary nail

Journal of Biomechanics, 2011

Research paper thumbnail of A new method to measure vertebral rotation from CT scans

European Spine Journal, 1999

Research paper thumbnail of Calcium Pyrophosphate Dihydrate Crystal Deposition Disease: Nomenclature and Diagnostic Criteria

Annals of Internal Medicine, 1977

Excerpt The variety of names suggested for the condition associated with deposits of calcium pyro... more Excerpt The variety of names suggested for the condition associated with deposits of calcium pyrophosphate dihydrate crystals is exceeded only by the variations of its clinical presentation. "Artic...

Research paper thumbnail of In vivo investigation of calcium phosphate coatings on Ti6-Al-4V alloy substrates using lactic acid - sodium lactate buffered synthetic body fluid

Acta Orthopaedica et Traumatologica Turcica, 2013

The aim of this study was to evaluate the mode of failure and biomechanical characteristics of Ti... more The aim of this study was to evaluate the mode of failure and biomechanical characteristics of Ti-6Al-4V anchors biomimetically coated with calcium phosphate (CaP) for soft tissue fixation to bone in an animal model. The current study included 14 adult New Zealand white rabbits equally divided into two groups. Calcium phosphate-coated Ti-6Al-4V anchors were used in the test group and non-coated Ti-6Al-4V anchors in the control group. A new approach was applied to synthesize the CaP coatings via the biomimetic growth in the Lac-SBF containing Ca(2+) and PO4(3-) ions, Na-lactate and lactic acid (HL). Titanium anchors were implanted into the right tibia, followed by biomechanical tensile strength tests. Histological studies were carried out after removal of anchors (bone-implant surface). The CaP-coated Ti-6Al-4V anchors had significantly higher tensile strength (p=0.003) and displacement values (p=0.004) than the non-coated anchors. Control group scores were higher than those of the test group (14 and 9, respectively) in tensile strength tests. The new CaP coating can be used in orthopedic surgery as catalyzer to improve bone ingrowth. We believe that our research will form a model for further research on biomimetic coatings on Ti-6Al-4V substrates.

Research paper thumbnail of Aneurysmal bone cyst healing response with intramedullary lengthening nail

Acta Orthopaedica et Traumatologica Turcica, 2017

We report the treatment process of a pediatric patient with deformity and shortening in the arm a... more We report the treatment process of a pediatric patient with deformity and shortening in the arm after a recurrent aggressive aneurysmal bone cyst (ABC) in the proximal humerus. The patient was treated with curettage of the lesion and lengthening on an intramedullary nail following an osteotomy just distal to the ABC. The period of lengthening was approximately 50 days. At the end of the treatment the lengthening goal was achieved without any neurovascular complication. There was a minimal loss in shoulder hyperabduction due to the deformity of the humeral head.

Research paper thumbnail of Scapular spine base fracture with long outside-in superior or posterior screws with reverse shoulder arthroplasty

Clinics in Shoulder and Elbow

Background: The purpose of the present study was to determine how long superior screws alone or i... more Background: The purpose of the present study was to determine how long superior screws alone or in combination with posterior placement of metaglene screws protruding and penetrating into the scapular spine in reverse total shoulder arthroplasty affect the strength of the scapular spine in a fresh cadaveric scapular model.Methods: Seven fresh cadaver scapulas were allocated to the control group (short posterior and superior screws) and seven scapulas to the study group (spine base fixation with a 4-inch-long superior screw, three with both long superior and long posterior screws).Results: The failure load was lower in the spine fixation group (long screw [869 N] vs. short screw [1,123 N]); however, this difference did not reach statistical significance (p>0.05). All outside-in long superior or superior plus posterior screws failed due to scapular spine base fracture; failures in the short screw group were due to acromion fracture. An additional posterior outside-in screw failed t...

Research paper thumbnail of A review of current developments in three-dimensional scaffolds for medical applications

Turkish Journal of Plastic Surgery, 2021

Humans require treatment due to the loss of tissues after trauma and diseases. Tissue engineering... more Humans require treatment due to the loss of tissues after trauma and diseases. Tissue engineering is a growing field of engineering and medical science to restore, maintain, or improve function of damaged or diseased tissues. The use of three-dimension (3D) scaffolds in particular offers a potential option for patients with tissue deficiency. Polylactic acid (PLA), poly-caprolactone (PCL), polyether-ether-ketone (PEEK), and thermoplastic polyurethane (TPU) are biomaterials that are commonly used in tissue engineering. Their applications of pure material or composite and supportive materials are of great importance for clinical practices. This review provides information on biomaterials and major areas of application and discusses their advantages and disadvantages against each other. The literature search from the database PubMed was done for the key words 3D PLA, PCL, PEEK, and TPU separately and 2029 articles were identified. These articles were limited according to clinical, in vivo and observational studies published in English and 140 articles were evaluated for this review. We selected the main articles according to the current data of 3D scaffolds and identical articles were removed. Fifty articles were included in the review. Many studies have reported the advantages of 3D scaffolds with composite or supplement materials over pure materials in the medical treatment. The advances in the development of new 3D scaffolds hold great promise for the prospective applications in the medical treatment.