i Behzad - Academia.edu (original) (raw)
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International Research Journal of Engineering and Technology(IRJET0
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Antibiotics are the most widely prescribed misused and overused drugs especially in intensive car... more Antibiotics are the most widely prescribed misused and overused drugs especially in intensive care unit. The primary objective was to evaluate the current usage of antibiotics and investigate how the current patterns challenging with patient safety in a General Intensive Care Unit (GICU) retrospectively. Case Sheets of patients admitted to GICU of tertiary care hospital during 20st March 2012to 21st September 2012 were obtained from the Medical Record Department. The class, dose and total number of antibiotics were noted. Descriptive analysis was used to present the results. The mean age of patients was 50.55 years (SD =23.69). The average ICU stay was 18.05 days(SD=38.71). The main reasons for admission in GICU was multiple trauma (27.62%), cerebrovascular accidents (18.1%) and malignancy complications (15.24%).Mortality rate was significantly higher especially in patients that received antibiotics empirically. The most frequently prescribed antibiotics were Third-generation cephalosporins, Glycopeptides, Carbapenems and Quinolones. 58.09% of patients were given 1-3antibiotics, 31.43% of them were given greater than 4 antibiotics and10.43% did not received any antibiotic. Prescription of antibiotics was inappropriate for dosage and intervals of administration, adjustment for renal and hepatic current function and overlapping of antibiotics's spectrum. Average number of drugs and antibiotics per encountered was 6.98 and 2.84 respectively.Inappropriate and ineffective use of antibiotics is common in ICUs. These problems challenging with patient safety and can complicate therapeutic programs. Thus there is a rational reason to change the current prescribing practices for example, collaboration of clinical pharmacologists with therapeutic staff as a consultant and attendance of them in physician rounds in ICUs as a full member of the patient care team.
Antibiotics are the most widely prescribed misused and overused drugs especially in intensive car... more Antibiotics are the most widely prescribed misused and overused drugs especially in intensive care unit. The primary objective was to evaluate the current usage of antibiotics and investigate how the current patterns challenging with patient safety in a General Intensive Care Unit (GICU) retrospectively. Case Sheets of patients admitted to GICU of tertiary care hospital during 20st March 2012to 21st September 2012 were obtained from the Medical Record Department. The class, dose and total number of antibiotics were noted. Descriptive analysis was used to present the results. The mean age of patients was 50.55 years (SD =23.69). The average ICU stay was 18.05 days(SD=38.71). The main reasons for admission in GICU was multiple trauma (27.62%), cerebrovascular accidents (18.1%) and malignancy complications (15.24%).Mortality rate was significantly higher especially in patients that received antibiotics empirically. The most frequently prescribed antibiotics were Third-generation cephalosporins, Glycopeptides, Carbapenems and Quinolones. 58.09% of patients were given 1-3antibiotics, 31.43% of them were given greater than 4 antibiotics and10.43% did not received any antibiotic. Prescription of antibiotics was inappropriate for dosage and intervals of administration, adjustment for renal and hepatic current function and overlapping of antibiotics's spectrum. Average number of drugs and antibiotics per encountered was 6.98 and 2.84 respectively.Inappropriate and ineffective use of antibiotics is common in ICUs. These problems challenging with patient safety and can complicate therapeutic programs. Thus there is a rational reason to change the current prescribing practices for example, collaboration of clinical pharmacologists with therapeutic staff as a consultant and attendance of them in physician rounds in ICUs as a full member of the patient care team.