irmadita citrashanty - Academia.edu (original) (raw)

Papers by irmadita citrashanty

Qanun medika : jurnal kedokteran Fakultas Kedokteran FKUM Surabaya, Jan 30, 2023

Bali Medical Journal, Apr 21, 2022

Intisari Sains Medis, Dec 7, 2022

Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya

Basal cell carcinoma (BCC) is the most common skin cancer, usually occurring in the sun-exposed a... more Basal cell carcinoma (BCC) is the most common skin cancer, usually occurring in the sun-exposed area, such as the head and neck, but also seen in less common areas like the upper or lower extremities. The initial treatment of BCC lesions is completing tumor removal. One of the standard therapy for BCC is wide surgical excision, as it is highly efficacious. A 76-year-old female patient complained of a wounded blackish lump on the left upper extremity for about 2 years. It started small, then grew bigger. Complained of itchiness, but no pain. The lump easily bled when accidentally touched. Dermatology examination identified a hyperpigmented nodule about 1.5 cm, with a clear border, irregular raised edges, slightly rough surface, and erosion. A dermoscopy examination showed short-fine telangiectasia, blue-grey ovoid nests, and ulceration. The patient was diagnosed with suspected BCC and underwent biopsy, also wide excision surgery. Histopathology showed pigmented BCC. One month later, ...

2022 International Conference on Healthcare Engineering (ICHE)

Bali Medical Journal

Background: Psoriasis is a complex, chronic disease with increasing global incidence. Studies on ... more Background: Psoriasis is a complex, chronic disease with increasing global incidence. Studies on the effectiveness of psoriasis therapy in Indonesia are limited. This study aimed to evaluate the patient’s clinical improvement with moderate-to-severe psoriasis vulgaris using the Psoriasis Area and Severity Index with ≥75% score reduction (PASI75). Methods: This is a retrospective study involving patients diagnosed with psoriasis vulgaris who visited the Dermatology and Venereology Outpatient Clinic in Dr. Soetomo General Hospital between January 2016 and December 2018. The electronic medical record obtained data on demographic characteristics, the number of visits, psoriasis at initial (PASI) score before and after treatment, type and dose of treatment, and comorbidities. Data were analyzed using SPSS version 23 for Windows. Results: Overall, 54 patients with psoriasis vulgaris were included. Almost all subjects were adults (≥18 years old) and presented with severe PASI (PASI score &...

Berkala Ilmu Kesehatan Kulit dan Kelamin, Nov 30, 2022

Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya

Basal cell carcinoma (BCC) is a non-keratinization cell-derived neoplasm. Surgical excision is t... more Basal cell carcinoma (BCC) is a non-keratinization cell-derived neoplasm. Surgical excision is the most common way to remove a tumor. The excision depends on the tumor type, size, and location. This paper reported a 44- years-old woman presented with the chief complaint of a single bump that bleeds easily in the facial region that began one year ago. Dermatology examination revealed hyperpigmented plaque with an ulcer in central, solitary, oval, 2 cm x 1 cm in size, covered with blackish crust on top. A Dermoscopy examination showed blue dots and globules, arborizing vessels, and ulceration. Histopathology examination findings were in concordance with BCC. The patient was treated with elliptical surgical excision. The lesion was successfully removed and showed good results with minimal scarring. BCC occurs in 75% of all skin cancers. Elliptical surgical excision on the left cheek was performed after considering the location anatomy, defect size, age, and general condition patient a...

Bali Medical Journal

Background: Clavus and callus are common hyperkeratotic lesions that can be very painful and affe... more Background: Clavus and callus are common hyperkeratotic lesions that can be very painful and affect the quality of life. The clinicians are faced with various factors affecting the resolution of the lesion, and no treatment has been considered ideal. Surgical has been preferable to conservative treatment but is still more likely to increase patients' desirability due to great discomfort. This study aims to evaluate the factors contributing to the resolution of callus and clavus. Methods: Retrospective analysis was done on 25 medical records of patients who met the inclusion criteria. Factors contributing to the lesion resolution were identified and analyzed using the SPSS version 17 program. Result: Among 25 (33.7%) patients recruited for the study, 13 were (52%) male and 12 (48%) female. The most common types of lesions were clavus (20 [80%]). In both cases, the distribution of lesion locations was mostly found in the lower extremities (20 [80%]). Excision was performed in 21 c...

Intisari Sains Medis

Background: Sebaceous gland hyperplasia is a benign skin disorder in the form of macules or papul... more Background: Sebaceous gland hyperplasia is a benign skin disorder in the form of macules or papules which are generally < 1 mm in size, skin color or yellowish at the mouth of the pilosebaceous gland follicle.1 This disorder can cause cosmetic morbidity and psychosocial impacts for patients. There are various treatment modalities for sebaceous gland hyperplasia associated with the risk of pain, depigmentation, bleeding during the procedure, scarring, and recurrence. CO2 laser is one of the therapeutic approaches that are considered effective and safe. Case: A female patient came with the chief complaint of lumpy skin-colored lumps on the back of the ear to the left neck that had increased in number and had not been painful since about 4 years ago. Histopathological examination was performed on the lump showing hyperplasia of the sebaceous glands. The patient was treated with 2 CO2 Laser sessions with an even skin surface result. Observations made within 9 months after the procedu...

Lembaga Penyakit Tropis Universitas Airlangga, 2015

Proceedings of the 23rd Regional Conference of Dermatology, 2018

Latar belakang Mikosis superfisialis adalah infeksi jamur superfisial yang disebabkan oleh koloni... more Latar belakang Mikosis superfisialis adalah infeksi jamur superfisial yang disebabkan oleh kolonisasi jamur atau ragi. Indonesia merupakan negara tropis yang masih banyak didapatkan kasus tersebut. Tujuan Untuk mengevaluasi gambaran pasien serta penegakan diagnosis mikosis superfisialis yang meliputi jumlah kasus baru, distribusi menurut jenis kelamin, umur, jenis penyakit, pemeriksaan laboratorium dengan KOH 20% + tinta Parker, serta pemeriksaan kultur. Metode Penelitian ini dilakukan secara retrospektif pada pasien mikosis superfisialis di Divisi Mikologi Unit Rawat Jalan (URJ) Kulit dan Kelamin RSUD Dr. Soetomo Surabaya tahun 2008-2010. Dilakukan pencatatan data dari laporan tahunan/catatan medik mengenai jumlah pasien, umur, jenis kelamin, domisili, diagnosis dan pemeriksaan penunjang meliputi KOH 20% dan kultur. Hasil Dalam kurun waktu tahun 2008–2010, dermatofitosis merupakan jenis mikosis superfisialis yang terbanyak diderita, yaitu berturut-turut 59,5% (2008), 56,3% (2009) d...

Latar Belakang Beberapa studi mengemukakan bahwa peningkatan tumor necrosis factor–alpha (TNF-α) ... more Latar Belakang Beberapa studi mengemukakan bahwa peningkatan tumor necrosis factor–alpha (TNF-α) sebanding dengan derajat keparahan Eritema Nodosum Leprosum (ENL), sehingga sitokin ini dianggap sebagai seromarker. Sekresi adrenocorticotropin hormone (ACTH) meningkat akibat pelepasan sitokin proinflamasi, kemudian ACTH akan merangsang pelepasan glukokortikoid adrenal sebagai umpan balik. Apabila rangsangan sitokin ini berlangsung kronis, korteks adrenal akan mengalami kelelahan yang berakibat menurunnya serum kortisol. Pemberian kortikosteroid eksogen jangka panjang diduga menyebabkan terjadinya penurunan kortisol. Tujuan Mengevaluasi profil TNF-α dan kortisol serum pada pasien ENL yang diterapi kortikosteroid berdasarkan riwayat lamanya ENL. Metode Dua puluh satu subjek dilakukan pemeriksaan fisik, anamnesis riwayat ENL, dan pengambilan sampel darah jam 08.00-09.00 untuk melihat kadar TNF-α dan kortisol serum. Hasil Dari 21 sampel didapatkan rerata TNF-α serum sebesar 4,51 ± 1,7 ρg/...

Acta Dermatovenerologica Alpina Pannonica et Adriatica

Berkala Ilmu Kesehatan Kulit dan Kelamin

Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, prof... more Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, profile of cutaneous tumors in our institution has not been studied. Purpose: To evaluate profile of cutaneous tumors in Dermatology and Venerology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya, Indonesia. Methods: This is a descriptive retrospective study. Inclusion criteria was new cutaneous tumor patients. Exclusion criteria was incomplete data. Medical record and photograph database from 2019-2020 were assessed for demography, clinical features, histopathological examination and final diagnosis. Results: There were 379 (5,5%) cutaneous tumors among 6896 new patients at Dermatology and Venereology Outpatient Clinic. Overall, there were more female patients (53.7%) and age group of 0-45 years old (70.4%). Cutaneous tumors more commonly presented as papular (50.4%), multiple (56.5%), nonpigmented (58.3%), asymptomatic lesions (62.5%), with time from onset 0-24 months (66.2%) an...

Clinical Cases in Dermatology, 2022

Clinical Cases in Dermatology, 2022

Clinical Cases in Dermatology, 2022

International Journal of Health Sciences (IJHS), Jul 28, 2022

Current treatment guidelines include fluconazole as the main therapeutic option for treating oral... more Current treatment guidelines include fluconazole as the main therapeutic option for treating oral candidiasis infection in HIV/AIDS patients, but resistance increases. Several in vitro studies have shown that clove leaf essential oil with the main content of eugenol can be an alternative therapy for oral candidiasis that is resistant to fluconazole. This study was conducted to determine the zone of inhibition of clove leaf essential oil and fluconazole against Candida isolates species that cause oral candidiasis in HIV/AIDS patients. This study showed that the average fluconazole disk 25 μg/mL inhibition zone in 20 isolates of Candida albicans species was larger than non-albicans Candida species. The zone of inhibition of clove leaf essential oil was significantly lower than that of fluconazole (p < 0.05), except at a concentration of 15% against non-albicans Candida isolates. Clove leaf essential oil has an antifungal effect that can inhibit the growth of Candida species, so it can be considered an alternative antifungal therapy. Clove leaf essential oil concentration of 15% showed no significant difference in antifungal activity with the standard drug fluconazole in isolates of non-albicans Candida species.

Qanun medika : jurnal kedokteran Fakultas Kedokteran FKUM Surabaya, Jan 30, 2023

Bali Medical Journal, Apr 21, 2022

Intisari Sains Medis, Dec 7, 2022

Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya

Basal cell carcinoma (BCC) is the most common skin cancer, usually occurring in the sun-exposed a... more Basal cell carcinoma (BCC) is the most common skin cancer, usually occurring in the sun-exposed area, such as the head and neck, but also seen in less common areas like the upper or lower extremities. The initial treatment of BCC lesions is completing tumor removal. One of the standard therapy for BCC is wide surgical excision, as it is highly efficacious. A 76-year-old female patient complained of a wounded blackish lump on the left upper extremity for about 2 years. It started small, then grew bigger. Complained of itchiness, but no pain. The lump easily bled when accidentally touched. Dermatology examination identified a hyperpigmented nodule about 1.5 cm, with a clear border, irregular raised edges, slightly rough surface, and erosion. A dermoscopy examination showed short-fine telangiectasia, blue-grey ovoid nests, and ulceration. The patient was diagnosed with suspected BCC and underwent biopsy, also wide excision surgery. Histopathology showed pigmented BCC. One month later, ...

2022 International Conference on Healthcare Engineering (ICHE)

Bali Medical Journal

Background: Psoriasis is a complex, chronic disease with increasing global incidence. Studies on ... more Background: Psoriasis is a complex, chronic disease with increasing global incidence. Studies on the effectiveness of psoriasis therapy in Indonesia are limited. This study aimed to evaluate the patient’s clinical improvement with moderate-to-severe psoriasis vulgaris using the Psoriasis Area and Severity Index with ≥75% score reduction (PASI75). Methods: This is a retrospective study involving patients diagnosed with psoriasis vulgaris who visited the Dermatology and Venereology Outpatient Clinic in Dr. Soetomo General Hospital between January 2016 and December 2018. The electronic medical record obtained data on demographic characteristics, the number of visits, psoriasis at initial (PASI) score before and after treatment, type and dose of treatment, and comorbidities. Data were analyzed using SPSS version 23 for Windows. Results: Overall, 54 patients with psoriasis vulgaris were included. Almost all subjects were adults (≥18 years old) and presented with severe PASI (PASI score &...

Berkala Ilmu Kesehatan Kulit dan Kelamin, Nov 30, 2022

Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya

Basal cell carcinoma (BCC) is a non-keratinization cell-derived neoplasm. Surgical excision is t... more Basal cell carcinoma (BCC) is a non-keratinization cell-derived neoplasm. Surgical excision is the most common way to remove a tumor. The excision depends on the tumor type, size, and location. This paper reported a 44- years-old woman presented with the chief complaint of a single bump that bleeds easily in the facial region that began one year ago. Dermatology examination revealed hyperpigmented plaque with an ulcer in central, solitary, oval, 2 cm x 1 cm in size, covered with blackish crust on top. A Dermoscopy examination showed blue dots and globules, arborizing vessels, and ulceration. Histopathology examination findings were in concordance with BCC. The patient was treated with elliptical surgical excision. The lesion was successfully removed and showed good results with minimal scarring. BCC occurs in 75% of all skin cancers. Elliptical surgical excision on the left cheek was performed after considering the location anatomy, defect size, age, and general condition patient a...

Bali Medical Journal

Background: Clavus and callus are common hyperkeratotic lesions that can be very painful and affe... more Background: Clavus and callus are common hyperkeratotic lesions that can be very painful and affect the quality of life. The clinicians are faced with various factors affecting the resolution of the lesion, and no treatment has been considered ideal. Surgical has been preferable to conservative treatment but is still more likely to increase patients' desirability due to great discomfort. This study aims to evaluate the factors contributing to the resolution of callus and clavus. Methods: Retrospective analysis was done on 25 medical records of patients who met the inclusion criteria. Factors contributing to the lesion resolution were identified and analyzed using the SPSS version 17 program. Result: Among 25 (33.7%) patients recruited for the study, 13 were (52%) male and 12 (48%) female. The most common types of lesions were clavus (20 [80%]). In both cases, the distribution of lesion locations was mostly found in the lower extremities (20 [80%]). Excision was performed in 21 c...

Intisari Sains Medis

Background: Sebaceous gland hyperplasia is a benign skin disorder in the form of macules or papul... more Background: Sebaceous gland hyperplasia is a benign skin disorder in the form of macules or papules which are generally < 1 mm in size, skin color or yellowish at the mouth of the pilosebaceous gland follicle.1 This disorder can cause cosmetic morbidity and psychosocial impacts for patients. There are various treatment modalities for sebaceous gland hyperplasia associated with the risk of pain, depigmentation, bleeding during the procedure, scarring, and recurrence. CO2 laser is one of the therapeutic approaches that are considered effective and safe. Case: A female patient came with the chief complaint of lumpy skin-colored lumps on the back of the ear to the left neck that had increased in number and had not been painful since about 4 years ago. Histopathological examination was performed on the lump showing hyperplasia of the sebaceous glands. The patient was treated with 2 CO2 Laser sessions with an even skin surface result. Observations made within 9 months after the procedu...

Lembaga Penyakit Tropis Universitas Airlangga, 2015

Proceedings of the 23rd Regional Conference of Dermatology, 2018

Latar belakang Mikosis superfisialis adalah infeksi jamur superfisial yang disebabkan oleh koloni... more Latar belakang Mikosis superfisialis adalah infeksi jamur superfisial yang disebabkan oleh kolonisasi jamur atau ragi. Indonesia merupakan negara tropis yang masih banyak didapatkan kasus tersebut. Tujuan Untuk mengevaluasi gambaran pasien serta penegakan diagnosis mikosis superfisialis yang meliputi jumlah kasus baru, distribusi menurut jenis kelamin, umur, jenis penyakit, pemeriksaan laboratorium dengan KOH 20% + tinta Parker, serta pemeriksaan kultur. Metode Penelitian ini dilakukan secara retrospektif pada pasien mikosis superfisialis di Divisi Mikologi Unit Rawat Jalan (URJ) Kulit dan Kelamin RSUD Dr. Soetomo Surabaya tahun 2008-2010. Dilakukan pencatatan data dari laporan tahunan/catatan medik mengenai jumlah pasien, umur, jenis kelamin, domisili, diagnosis dan pemeriksaan penunjang meliputi KOH 20% dan kultur. Hasil Dalam kurun waktu tahun 2008–2010, dermatofitosis merupakan jenis mikosis superfisialis yang terbanyak diderita, yaitu berturut-turut 59,5% (2008), 56,3% (2009) d...

Latar Belakang Beberapa studi mengemukakan bahwa peningkatan tumor necrosis factor–alpha (TNF-α) ... more Latar Belakang Beberapa studi mengemukakan bahwa peningkatan tumor necrosis factor–alpha (TNF-α) sebanding dengan derajat keparahan Eritema Nodosum Leprosum (ENL), sehingga sitokin ini dianggap sebagai seromarker. Sekresi adrenocorticotropin hormone (ACTH) meningkat akibat pelepasan sitokin proinflamasi, kemudian ACTH akan merangsang pelepasan glukokortikoid adrenal sebagai umpan balik. Apabila rangsangan sitokin ini berlangsung kronis, korteks adrenal akan mengalami kelelahan yang berakibat menurunnya serum kortisol. Pemberian kortikosteroid eksogen jangka panjang diduga menyebabkan terjadinya penurunan kortisol. Tujuan Mengevaluasi profil TNF-α dan kortisol serum pada pasien ENL yang diterapi kortikosteroid berdasarkan riwayat lamanya ENL. Metode Dua puluh satu subjek dilakukan pemeriksaan fisik, anamnesis riwayat ENL, dan pengambilan sampel darah jam 08.00-09.00 untuk melihat kadar TNF-α dan kortisol serum. Hasil Dari 21 sampel didapatkan rerata TNF-α serum sebesar 4,51 ± 1,7 ρg/...

Acta Dermatovenerologica Alpina Pannonica et Adriatica

Berkala Ilmu Kesehatan Kulit dan Kelamin

Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, prof... more Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, profile of cutaneous tumors in our institution has not been studied. Purpose: To evaluate profile of cutaneous tumors in Dermatology and Venerology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya, Indonesia. Methods: This is a descriptive retrospective study. Inclusion criteria was new cutaneous tumor patients. Exclusion criteria was incomplete data. Medical record and photograph database from 2019-2020 were assessed for demography, clinical features, histopathological examination and final diagnosis. Results: There were 379 (5,5%) cutaneous tumors among 6896 new patients at Dermatology and Venereology Outpatient Clinic. Overall, there were more female patients (53.7%) and age group of 0-45 years old (70.4%). Cutaneous tumors more commonly presented as papular (50.4%), multiple (56.5%), nonpigmented (58.3%), asymptomatic lesions (62.5%), with time from onset 0-24 months (66.2%) an...

Clinical Cases in Dermatology, 2022

Clinical Cases in Dermatology, 2022

Clinical Cases in Dermatology, 2022

International Journal of Health Sciences (IJHS), Jul 28, 2022

Current treatment guidelines include fluconazole as the main therapeutic option for treating oral... more Current treatment guidelines include fluconazole as the main therapeutic option for treating oral candidiasis infection in HIV/AIDS patients, but resistance increases. Several in vitro studies have shown that clove leaf essential oil with the main content of eugenol can be an alternative therapy for oral candidiasis that is resistant to fluconazole. This study was conducted to determine the zone of inhibition of clove leaf essential oil and fluconazole against Candida isolates species that cause oral candidiasis in HIV/AIDS patients. This study showed that the average fluconazole disk 25 μg/mL inhibition zone in 20 isolates of Candida albicans species was larger than non-albicans Candida species. The zone of inhibition of clove leaf essential oil was significantly lower than that of fluconazole (p < 0.05), except at a concentration of 15% against non-albicans Candida isolates. Clove leaf essential oil has an antifungal effect that can inhibit the growth of Candida species, so it can be considered an alternative antifungal therapy. Clove leaf essential oil concentration of 15% showed no significant difference in antifungal activity with the standard drug fluconazole in isolates of non-albicans Candida species.