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Papers by islam kassem

Computer Guided 3D Facial esthetics Simulation integrating 3D Facial Guided Digital Smile Design

The Egyptian Journal of Surgery, 2018

Objective The aim of the study is to evaluate the efficiency and safety of mesh repair in emergen... more Objective The aim of the study is to evaluate the efficiency and safety of mesh repair in emergent complicated midline incisional hernias as well as the impact on the early postoperative (PO) morbidity and mortality to implement the best patient management procedure. Patients and methods The study includes 60 patients with emergent midline incisional hernias. Patients were divided according to the type of closure of hernia defect into two groups, group A (30 patients) was managed with a prosthetic mesh repair and group B (30 patients) was managed by primary suture repair. We used the alternation method as an allocation process. Patients in both groups were monitored during operations and along the PO period. The data collected include the patients’ condition at presentation, coexisting disease, operative data and PO complications, length of hospital stay, surgical site infection (SSI) and recurrence rates. Results A total of 60 patients underwent operations for emergent midline inci...

Gummy smile is considered a challenging esthetic problem both in assessment and management among ... more Gummy smile is considered a challenging esthetic problem both in assessment and management among the surgeons We present a new assessment method based on photographing with different angles and conjugated with CBCT We present different modalities of management varies between Botox injection, gingival surgery or Orthognathic surgery. Guide lines were concluded in assessment and management to provide further patient safety.

Journal of Natural Products, 2008

BMC Oral Health

Objective Loss of taste (ageusia) is a symptom observed following recovery from COVID-19 infectio... more Objective Loss of taste (ageusia) is a symptom observed following recovery from COVID-19 infection. The loss of taste and smell sensation may negatively affect patients’ quality of life (QoL). The present study aimed to evaluate the effectiveness of the Diode Laser in managing loss of taste sensation in patients with post-COVID syndrome versus the placebo. Material and method The study sample was 36 patients who complained of persistent loss of taste sensation following COVID-19. The patients were randomly assigned to one of the two groups according to the received treatment: Group I (laser treatment) and Group II (light treatment), with each patient receiving a diode laser treatment or placebo from the same operator. Taste sensation was subjectively measured after treatment for four weeks. Results The results demonstrated a significant difference between both groups regarding taste restoration after one month (p = 0.041), with Group II having a significantly higher percentage of ca...

Computer Guided 3D Facial esthetics Simulation integrating 3D Facial Guided Digital Smile Design

Journal of Fungi, 2021

Background: Since the novel coronavirus disease (COVID-19) outbreak, the cases of COVID-19 co-inf... more Background: Since the novel coronavirus disease (COVID-19) outbreak, the cases of COVID-19 co-infections have been increasingly reported worldwide. Mucormycosis, an opportunistic fungal infection caused by members of the Mucorales order, had been frequently isolated in severely and critically ill COVID-19 patients. Methods: Initially, the anamnestic, clinical, and paraclinical features of seven COVID-19-associated mucormycosis (CAM) cases from Egypt were thoroughly reported. Subsequently, an extensive review of the literature was carried out to describe the characteristics of CAM cases globally, aiming to explore the potential risk factors of mortality in CAM patients. Results: Out of the seven reported patients in the case series, five (71.4%) were males, six (85.7%) had diabetes mellitus, and three (42.9%) had cardiovascular disease. All patients exhibited various forms of facial deformities under the computed tomography scanning, and two of them tested positive for Mucorales usin...

Journal of Medical Virology, 2021

Dermatologic Therapy, 2020

through the copyediting, typesetting, pagination and proofreading process which may lead to diffe... more through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/dth.14479 Letter The Manifestation of Oral Mucositis in COVID-19 Patients: A case-series Author(s) Abanoub RIAD,1 Islam KASSEM,2 Mai BADRAH,3 and Miloslav KLUGAR1 Affiliation(s) 1 Czech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic 2 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University, Port Said Street 293, 213 11 Alexandria, Egypt 3 Department of Internal Medicine, Faculty of Medicine, Alexandria University, Port Said Street 293, 213 11 Alexandria, Egypt Corresponding Author Dr Abanoub RIAD, DDS P.O.: Czech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic Email: abanoub.riad@med.muni.cz

Journal of General Internal Medicine, 2020

BACKGROUND: Understanding the impact of the COVID-19 pandemic on healthcare workers (HCW) is cruc... more BACKGROUND: Understanding the impact of the COVID-19 pandemic on healthcare workers (HCW) is crucial. OBJECTIVE: Utilizing a health system COVID-19 research registry, we assessed HCW risk for COVID-19 infection, hospitalization, and intensive care unit (ICU) admission. DESIGN: Retrospective cohort study with overlap propensity score weighting. PARTICIPANTS: Individuals tested for SARS-CoV-2 infection in a large academic healthcare system (N = 72,909) from March 8-June 9, 2020, stratified by HCW and patient-facing status. MAIN MEASURES: SARS-CoV-2 test result, hospitalization, and ICU admission for COVID-19 infection. KEY RESULTS: Of 72,909 individuals tested, 9.0% (551) of 6145 HCW tested positive for SARS-CoV-2 compared to 6.5% (4353) of 66,764 non-HCW. The HCW were younger than the non-HCW (median age 39.7 vs. 57.5, p < 0.001) with more females (proportion of males 21.5 vs. 44.9%, p < 0.001), higher reporting of COVID-19 exposure (72 vs. 17%, p < 0.001), and fewer comorbidities. However, the overlap propensity score weighted proportions were 8.9 vs. 7.7 for HCW vs. non-HCW having a positive test with weighted odds ratio (OR) 1.17, 95% confidence interval (CI) 0.99-1.38. Among those testing positive, weighted proportions for hospitalization were 7.4 vs. 15.9 for HCW vs. non-HCW with OR of 0.42 (CI 0.26-0.66) and for ICU admission: 2.2 vs. 4.5 for HCW vs. non-HCW with OR of 0.48 (CI 0.20-1.04). Those HCW identified as patient facing compared to not had increased odds of a positive SARS-CoV-2 test (OR 1.60, CI 1.08-2.39, proportions 8.6 vs. 5.5), but no statistically significant increase in hospitalization (OR 0.88, CI 0.20-3.66, proportions 10.2 vs. 11.4) and ICU admission (OR 0.34, CI 0.01-3.97, proportions 1.8 vs. 5.2). CONCLUSIONS: In a large healthcare system, HCW had similar odds for testing SARS-CoV-2 positive, but lower odds of hospitalization compared to non-HCW. Patientfacing HCW had higher odds of a positive test. These results are key to understanding HCW risk mitigation during the COVID-19 pandemic.

Oral Diseases, 2020

Dear Editor, We have read with great interest the correspondence of Rodriguez et al. (2020) which... more Dear Editor, We have read with great interest the correspondence of Rodriguez et al. (2020) which demonstrated angular cheilitis (AC) in two patients of coronavirus disease (COVID-19) (Díaz Rodríguez et al., 2020). Therefore, we aim to report according to the CARE guidelines, a series of 17 laboratory-confirmed COVID-19 patients with AC (Gagnier et al., 2013). The referenced patients sought care at our department from April to June 2020 due to pain related to either one or both oral commissures. All included patients had previously undergone a polymerase chain reaction (PCR) testing for SARS-COV-2, which confirmed their infection with a mean cycle threshold (Ct) value of 28.71 ± 5.22 (17– 34). Their mean age was 39.94 ± 13 (20–64) years old, and twelve (70.6%) of them were females. In regard to the characteristic symptoms of COVID-19, four patients (23.5%) had persistent fever, three patients (17.6%) had pharyngitis, and two patients (11.8%) had ageusia. While one patient (5.9%) had lost the mandibular first molar, one patient (5.9%) had reported bruxism previously, and two patients (11.8%) had presented signs of dental attrition. All patients complained of excessive salivation during the preceding days of their examination. Clinical examination has revealed reddish swollen patches corresponding to AC found unilaterally on the left commissure of 11 patients (64.7%), the right commissure of four patients (23.5%), and bilaterally in two patients (11.8%). The day of PCR testing was set as a reference time point for estimating the onset of AC. The mean onset of AC was 1.82 ± 0.95 (0–3) days, and the mean duration was 3.35 ± 1.77 (2–8) days. Five patients (29.4%) had generalized cheilitis in addition to AC. The pain severity was subjectively assessed by the patients using an 11-item numerical rating scale (NRS) when with “0” denoting “no pain” and “10” denoting “pain as bad as you can imagine” (Williamson & Hoggart, 2005). The mean pain severity was 5.06 ± 1.89 (2–9), and the mean pain duration was 2.41 ± 0.87 (2–5) days. The patients received symptomatic treatment, including mouthwash of Chlorhexidine Gluconate 0.3% and antifungal ointment of Nystatin to ease their pain. The statistical analysis revealed that age and gender did not have a significant association with any of the clinical or laboratory variables. The duration of pain was strongly correlated with pain severity and the duration of AC until its complete recovery (Pearson Correlation = .526, and .625; p = .030, and .007, respectively). All the investigated patients agreed to use their clinical and laboratory results for academic purposes while concealing their identifying personal data. Our findings rule out the possibility of decreased vertical dimension as a local factor for developing AC; because the majority of our patients had their first molars in occlusion and did not present signs of bruxism or dental attrition. The increased expression of angiotensin-converting enzyme II (ACE2) in salivary glands underpinned by the high positivity of salivary samples for SARS-COV-2 can cause salivary glands disorders such as acute parotitis which may affect the salivary consistency in terms of increased serous secretion and enzyme content (Riad et al., 2020). However, there is a lack of evidence on salivary consistency and flow of COVID-19 patients, the increased salivation reported by our patients might cause AC as the salivary enzymes can irritate the skin of the mouth corners leading to maceration and digestion. (Park et al., 2011). On reviewing the emerging evidence of cheilitis in relation to COVID-19, twenty-six patients were reported to have various types of cheilitis. In Moscow, Khabadze et al. (2020) demonstrated that out of 90 hospitalized COVID-19 patients with oral mucocutaneous manifestations, there were 21 patients (23.3%) presented with AC associated in some of them with facial xeroderma and petechiae of buccal mucosa (Khabadze et al., 2020). In the case-series of Rodríguez et al. (2020), a 53-year-old male patient reported burning sensation with unilateral AC complicated by persistent anosmia and dysgeusia that lasted even after the relief of AC. There was also a 78-year-old hospitalized female with AC associated with pseudomembranous candidiasis lesions on the tongue and palate (Díaz Rodríguez et al., 2020). The youngest case was reported in Italy, for a 9-year-old Down's syndrome male patient who complained of symptomatic glossitis adjacent to mild cheilitis while being SARS-COV-2 positive (Mazzotta et al., 2020). Alsibai et al. (2020) described pustular, erythematous rash on the upper trunk in association with cheilitis in a 66-year-old recently recovered female patient (Drak Alsibai et al., 2020). A rare adult patient with Kawasakilike multisystem inflammatory syndrome had cheilitis associated with left neck swelling, periorbital edema, and targetoid erythematous while being SARS-COV-2 positive (Shaigany et al., 2020). Cheilitis and…

Special Care in Dentistry, 2020

Dear Editor, Halitosis is a reflective condition for an array of systemic insults such as respira... more Dear Editor, Halitosis is a reflective condition for an array of systemic insults such as respiratory, otolaryngologic and gastrointestinal pathologies that may alter salivary characteristics and tongue dorsum susceptibility for hosting anaerobic microorganisms. The high prevalence of halitosis globally requires a multidisciplinary approach for its diagnosis, assessment and treatment to discriminate between genuine, pseudoand denied halitosis based on subjective metrics.1 As with other circulating pandemics, halitosis has been greatly challenged by the outbreak of the coronavirus disease (COVID-19), and a few confirmed cases were reported to present with halitosis while being actively infected.2 We hereby aim to report according to the CARE guidelines, the demographic, clinical and laboratory characteristics of eighteen patients with confirmed COVID-19 without any relevant medical history, who experienced new-onset halitosis during their course of infection.3 The referenced patients sought care at our department between May and August 2020 due to an offensive oral malodour that precipitated notable psychosocial distress, especially with their spouses. All patients had previously undergone polymerase chain reaction (PCR) testing for severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) for various reasons, for instance: before-travel screening (22.2%), after-travel screening (27.8%), being in contact with a positive case (22.2%), presenting with mild symptoms such as fatigue (22.2%) andmoderate symptoms (5.6%). The PCR test confirmed their infectionwith amean cycle threshold value of 25.72 ± 5.5 (15-34) (Table 1). Their mean age was 35.11 ± 13.3 (18-72) years old; 14 patients (77.8%) were females, and three patients (16.7%) were smokers. Regarding the characteristic symptoms of COVID-19, two patients (11.1%) had persistent fever, a further two patients (11.1%) had anosmia, one (5.6%) had ageusia, and one (5.6%) presented with a dry cough. Nine of the 18 patients were prescribed medications, where four (22.2%) were taking paracetamol, three (16.7%) were taking ibuprofen, one (5.6%)was taking prednisolone, and one (5.6%) was prescribed chloroquine. The Oral Health Assessment Tool was used to evaluate the oral hygiene status of the investigated patients which

Dermatologic Therapy, 2021

Dear Editor We have read with great interest the review of Iranmanesh et al. (2020) on oral manif... more Dear Editor We have read with great interest the review of Iranmanesh et al. (2020) on oral manifestations of coronavirus diseases (COVID-19) which demonstrated the emergence of aphthous-like lesions in 16 cases thus suggesting that neutrophil chemotaxis, stress, and immunosuppression could be causal pathways for this condition to appear in COVID-19 patients. As a result of this, we aim to report according to the CARE guidelines, the characteristics of 21 laboratory-confirmed COVID-19 patients with aphthous stomatitis. We have also performed an updated literature search in Ovid MEDLINE, EMBASE, Cochrane Library, Epistemonikos from inception until November 26th, 2020 with a combination of keywords (COVID-19 or SARS-CoV-2) and aphthous. A retrospective analysis of our hospital records for COVID-19 patients during the period of April-September 2020 revealed that out of 1237 patients tested positive by our screening clinic, 21 patients (1.7%) complained of intra-oral pain related to aphthous stomatitis. The patients had undertaken polymerase chain reaction (PCR) testing of SARS-COV-2 due to various purposes including pre-travel (14.3%) and post-travel (9.5%) screening, direct (9.5%) and indirect (4.8%) contact with an infected case, presenting with mild (42.9%), and moderate (19%) respiratory symptoms (Table 1). Their mean age was 31.57 ± 11.01 (16-56) years old, and 17 patients (81%) were females. While the vast majority were nonsmokers, only two patients (9.5%) were smokers. The PCR test confirmed their infection with a mean cycle threshold (Ct) value of 25.76 ± 6.21 (12-32). Regarding their characteristic symptoms of COVID-19, three patients (14.3%) had persistent fever, five patients (23.8%) had a dry cough, five patients (23.8%) had anosmia, and two patients (9.5%) had ageusia. According to the Australian classification for COVID-19, 18 patients (85.7%) experienced a mild course of the disease, whereas 3 patients (14.3%) had a moderate course. On intraoral examination, solitary ulcerative white halos with well-defined erythematous margins were observed in the buccal mucosa (33.3%), upper lip (14.3%), lower lip (14.3%), tongue (14.3%), palate (9.5%), gingiva (9.5%) and both of palate and gingiva (4.8%). The mean size of the ulcers was 2 ± 0.86 (1–4) mm, and they caused pain with a mean intensity of 5.38 ± 1.5 (3–8) which was measured by means of an 11-item numerical rating scale (NRS) when with “0” denoting “no pain” and “10” denoting “pain as bad as you can imagine”. The patients were asked whether they had experienced similar ulcerative lesions previously and based on their negative answer, the recurrent aphthous stomatitis (RAS) was ruled out. To manage their pain, 18 patients (85.7%) were prescribed chlorhexidine gluconate 0.12% (CHX) mouthwash, and 3 patients (14.3%) were prescribed paracetamol (PCM). The pain duration was reported by 19 patients with a mean of 2.68 ± 0.67 (2–4) days; however, 2 patients were missed from the follow up. It is worthy to note that prevalence of aphthous stomatitis among COVID-19 patients could have been underestimated because we had not performed an intra-oral examination for all positive COVID-19 cases in order to confirm whether they had aphthous or not; nevertheless, our records are based on subjective reporting by the patients. Inferential statistics revealed that pain duration was significantly lower in patients treated with CHX (2.50 ± 0.52 days) than patients treated with PCM (3.67 ± 0.58 days); t(17) = −3.54, P = .003. This difference could be attributed to the severity of the aphthous condition, not to the drugs themselves. In case of CHX, patients had higher mean pain intensity (5 ± 1.24 vs 7.67 ± 0.58) and ulcer size (1.83 ± 0.79 vs 2.67 ± 1.15) than in case of PCM; t(19, 19) = −3.61, −1.61; P = .002, .125, respectively. Gender and age were not associated with any of the aphthous characteristics; however, tobacco smoking was the only risk factor significantly associated with pain intensity, the onset of aphthous stomatitis, anosmia, and ageusia P = .032, 0.042, .006, and ≤.001, respectively. On reviewing the currently growing evidence on aphthous stomatitis of COVID-19 patients, we have found 22 cases reported in 8 publications (7 case reports, 1 prevalence study). Fourteen cases (63.6%) were from Americas, five (22.7%) from Europe, two (9%) from the Middle East, and one (4.5%) from Asia-Pacific (Table 2). The aphthous lesions were equally distributed across gender; however, female predominance was noticed in the prevalence study of Florida, which is similar to our series. Seventeen patients (77.3%) were below 40 years old; similarly, the majority of our series (80.1%) was below 40 years old. The onset of aphthous lesions was reported in 10 patients only; it was estimated using the latency period since COVID-19 symptoms emergence which ranged between 0 and 10 days with two patients experienced aphthous stomatitis concurrently with COVID-19 symptoms onset. The…

Journal of Medical Virology, 2020

In this paper a novel intermediate view synthesis algorithm for 3D video rendering is presented. ... more In this paper a novel intermediate view synthesis algorithm for 3D video rendering is presented. The proposal is based on the representation of the pixels to be warped as intervals of finite length. The warping, hole-filling and merging stages of the view synthesis procedure can be recast according to this notation with significant advantages from the point of view of image synthesis quality, algorithm complexity and memory requirements. A novel interpolation rule based on the definition of a foreground and a background weight associated to each warped pixel is proposed and compared with linear interpolation based on pixels distance. The experimental results show that the designed technique yields a significant gain in terms of rendered image quality, while at the same time halving the execution time with respect to the MPEG view synthesis reference software.

Oral Diseases, 2020

In connection with our earlier correspondence on the epidemiologic significance of the coronaviru... more In connection with our earlier correspondence on the epidemiologic significance of the coronavirus disease (COVID-19)-related oral manifestations, it has been evident that larger observational studies following rigorous reporting guidelines are inevitable for better understanding of the ongoing pandemic from oral disease perspective (Riad, Klugar, & Krsek, 2020). Hereby, we describe, according to the STROBE guidelines, a series of 15 confirmed COVID-19 cases with acute parotitis symptoms that were highly attributed to the direct infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Von Elm et al., 2007).

Computer Guided 3D Facial esthetics Simulation integrating 3D Facial Guided Digital Smile Design

The Egyptian Journal of Surgery, 2018

Journal of Natural Products, 2008

BMC Oral Health

Computer Guided 3D Facial esthetics Simulation integrating 3D Facial Guided Digital Smile Design

Journal of Fungi, 2021

Journal of Medical Virology, 2021

Dermatologic Therapy, 2020

Journal of General Internal Medicine, 2020

Oral Diseases, 2020

Special Care in Dentistry, 2020

Dermatologic Therapy, 2021

Journal of Medical Virology, 2020

Oral Diseases, 2020