jake bell - Academia.edu (original) (raw)
Papers by jake bell
This paper describes two recently developed templates for displaying geospatially-indexed estimat... more This paper describes two recently developed templates for displaying geospatially-indexed estimates: linked micromap (LM) plots and conditioned choropleth (CC) maps. Two common goals in developing these templates were to integrate more statistical information in a display than a traditional choropleth map and to provide for more rapid assessment of statistical and spatial patterns than would be provided by a table. The particular layout and integration of information makes these templates distinct from previous graphical templates.
Computing in Science and Engineering, 2002
Linked micromap (LM) plots offer a new template for displaying spatially indexed statistical summ... more Linked micromap (LM) plots offer a new template for displaying spatially indexed statistical summaries. One can use LM plots to visualize complex data in many areas. This paper introduces web-based interactive LM plots, a statistical data visualization system that integrates geographical data manipulation, visualization, interactive statistical graphics, and web-based Java technologies. The system effectively presents the complex and large-volume sample
This paper describes two recently developed templates for displaying geospatially-indexed estimat... more This paper describes two recently developed templates for displaying geospatially-indexed estimates: linked micromap (LM) plots and conditioned choropleth (CC) maps. Two common goals in developing these templates were to integrate more statistical information in a display than a traditional choropleth map and to provide for more rapid assessment of statistical and spatial patterns than would be provided by a table. The particular layout and integration of information makes these templates distinct from previous graphical templates.
We report on recent progress in the control of optical modes toward the improvement of commercial... more We report on recent progress in the control of optical modes toward the improvement of commercial high-performance diode laser modules. Control of the transverse mode has allowed scaling of the optical mode volume, increasing the peak output power of diode laser emitters by a factor of two. Commercially-available single emitter diodes operating at 885 nm now exhibit >25 W peak (12 W rated) at >60% conversion efficiency. In microchannel-cooled bar format, these lasers operate >120 W at 62% conversion efficiency. Designs of similar performance operating at 976 nm have shown >37,000 equivalent device hours with no failures. Advances in the control of lateral modes have enabled unprecedented brightness scaling in a fiber-coupled package format. Leveraging scalable arrays of single emitters, the conductively-cooled nLIGHT Pearl TM package now delivers >80 W peak (50 W rated) at >53% conversion efficiency measured from a 200-μm core fiber output and >45 W peak (35 W rated) at >52% conversion efficiency measured from a 100-μm fiber output. nLIGHT has also expanded its product portfolio to include wavelength locking by means of external volume Bragg gratings. By controlling the longitudinal modes of the laser, this technique is demonstrated to produce a narrow, temperature-stabilized spectrum, with minimal performance degradation relative to similar free-running lasers.
Hepatology, 1989
Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and c... more Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and chronic obliterative arteriopathy. A quantitative histometric analysis was performed to document the extent of bile duct loss, the size of the “vanished” ducts and the extent of chronic obliterative arteriopathy and to determine whether there was any relationship between chronic obliterative arteriopathy and bile duct loss. All failed liver allograft specimens with chronic rejection were reviewed and categorized according to the degree of chronic obliterative arteriopathy, assessed by the degree of luminal narrowing of hilar hepatic artery branches. Histometric analysis of the grafts revealed: (i) there was a loss of small portal arterioles (<35 μm); (ii) bile ducts which should accompany arteries <35, 35 to 54 or 55 to 74 μm in diameter were missing, with the greatest decrease occurring among the smallest ducts; (iii) bile duct loss was seen in the absence of significant large vessel chronic obliterative arteriopathy, and (iv) the severity of arteriole and bile duct loss, as well as the size of the vanished ducts, was directly proportional to the degree of chronic obliterative arteriopathy. Furthermore, the size of the “vanished” bile ducts in liver allografts appeared to differ from the size of ducts destroyed in primary biliary cirrhosis. These studies offer indirect, but suggestive proof that two mechanisms are operative in the bile duct loss seen in chronic rejection: direct lymphocytotoxicity and ischemic damage.
Applied Physics Letters, 2009
Inspired by the natural design of bacterial flagella, we report artificial bacterial flagella ͑AB... more Inspired by the natural design of bacterial flagella, we report artificial bacterial flagella ͑ABF͒ that have a comparable shape and size to their organic counterparts and can swim in a controllable fashion using weak applied magnetic fields. The helical swimmer consists of a helical tail resembling the dimensions of a natural flagellum and a thin soft-magnetic "head" on one end. The swimming locomotion of ABF is precisely controlled by three orthogonal electromagnetic coil pairs. Microsphere manipulation is performed, and the thrust force generated by an ABF is analyzed. ABF swimmers represent the first demonstration of microscopic artificial swimmers that use helical propulsion. Self-propelled devices such as these are of interest in fundamental research and for biomedical applications.
School Pride: "Playing a contributing role in maintaining and improving all aspects of a school's... more School Pride: "Playing a contributing role in maintaining and improving all aspects of a school's environment, programs and activities." We have been holding many discussions with our middle school students over the past couple of months regarding school pride. Through these discussions, we are attempting to educate our students on what school pride is and what it looks like. School pride can extend itself from having great spirit, voice and support at a sporting event, to picking up a gum wrapper in the school hallway. Obviously, school pride encompasses many, many things. However, one thing we do know at Wahoo Middle School is that it is a priority. We have been challenging our students, and will continue to challenge them regarding school pride. We have high expectations for our students and the care and pride they have within our school building. We expect that our students keep their locker areas, classroom areas, and lunch room areas clean and neat. In addition, it is our expectation that our students show school pride and respect by following our guidelines regarding school dress. These are just two examples of topics being discussed within our school building. As a parent, please encourage your child to take great care and pride in their school. Together, we can insure that the Wahoo Middle School is truly a GREAT place to learn!!!
Digestive Diseases and Sciences, 1990
The effect of ranitidine administration upon the hepatotoxic effect produced by a multidose aceta... more The effect of ranitidine administration upon the hepatotoxic effect produced by a multidose acetaminophen administration regimen was examined. Seventy-two dogs received three subcutaneous injections of acetaminophen (750, 200, 200 mg/kg body wt) in DMSO (600 mg/ml) at time zero, 9 hr later, and 24 hr after the first dose. Ten control animals (group I) were not given ranitidine, the remaining 62 dogs received an intramus-cular injection of ranitidine 30 min before each acetaminophen dose. Three different doses of ranitidine were used (mg/kg body wt): 50 mg, group II (33 dogs); 75 mg, group III (14 dogs); 120 mg, group IV (15 dogs). Ranitidine reduced the expected acetaminophen-induced hepatoxicity in a dose-response manner. Moreover, a significant correlation was found between the ranitidine dose and the survival rate, as evidenced by transaminase levels in the serum and histology of the liver. This model of fulminant hepatic failure induced by acetaminophen and its modulation with ranitidine provides clinical investigators with a research tool that will be useful in the future investigation of putative medical and surgical therapies being investigated for use in the clinical management of fulminant hepatic failure. Because of the size of the animal used in this model, frequent and serial analyses of blood and liver were available for study to determine the effect of therapy within a given animal as opposed to within groups of animals.
This paper describes two recently developed templates for displaying geospatially-indexed estimat... more This paper describes two recently developed templates for displaying geospatially-indexed estimates: linked micromap (LM) plots and conditioned choropleth (CC) maps. Two common goals in developing these templates were to integrate more statistical information in a display than a traditional choropleth map and to provide for more rapid assessment of statistical and spatial patterns than would be provided by a table. The particular layout and integration of information makes these templates distinct from previous graphical templates.
Computing in Science and Engineering, 2002
Linked micromap (LM) plots offer a new template for displaying spatially indexed statistical summ... more Linked micromap (LM) plots offer a new template for displaying spatially indexed statistical summaries. One can use LM plots to visualize complex data in many areas. This paper introduces web-based interactive LM plots, a statistical data visualization system that integrates geographical data manipulation, visualization, interactive statistical graphics, and web-based Java technologies. The system effectively presents the complex and large-volume sample
This paper describes two recently developed templates for displaying geospatially-indexed estimat... more This paper describes two recently developed templates for displaying geospatially-indexed estimates: linked micromap (LM) plots and conditioned choropleth (CC) maps. Two common goals in developing these templates were to integrate more statistical information in a display than a traditional choropleth map and to provide for more rapid assessment of statistical and spatial patterns than would be provided by a table. The particular layout and integration of information makes these templates distinct from previous graphical templates.
We report on recent progress in the control of optical modes toward the improvement of commercial... more We report on recent progress in the control of optical modes toward the improvement of commercial high-performance diode laser modules. Control of the transverse mode has allowed scaling of the optical mode volume, increasing the peak output power of diode laser emitters by a factor of two. Commercially-available single emitter diodes operating at 885 nm now exhibit >25 W peak (12 W rated) at >60% conversion efficiency. In microchannel-cooled bar format, these lasers operate >120 W at 62% conversion efficiency. Designs of similar performance operating at 976 nm have shown >37,000 equivalent device hours with no failures. Advances in the control of lateral modes have enabled unprecedented brightness scaling in a fiber-coupled package format. Leveraging scalable arrays of single emitters, the conductively-cooled nLIGHT Pearl TM package now delivers >80 W peak (50 W rated) at >53% conversion efficiency measured from a 200-μm core fiber output and >45 W peak (35 W rated) at >52% conversion efficiency measured from a 100-μm fiber output. nLIGHT has also expanded its product portfolio to include wavelength locking by means of external volume Bragg gratings. By controlling the longitudinal modes of the laser, this technique is demonstrated to produce a narrow, temperature-stabilized spectrum, with minimal performance degradation relative to similar free-running lasers.
Hepatology, 1989
Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and c... more Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and chronic obliterative arteriopathy. A quantitative histometric analysis was performed to document the extent of bile duct loss, the size of the “vanished” ducts and the extent of chronic obliterative arteriopathy and to determine whether there was any relationship between chronic obliterative arteriopathy and bile duct loss. All failed liver allograft specimens with chronic rejection were reviewed and categorized according to the degree of chronic obliterative arteriopathy, assessed by the degree of luminal narrowing of hilar hepatic artery branches. Histometric analysis of the grafts revealed: (i) there was a loss of small portal arterioles (<35 μm); (ii) bile ducts which should accompany arteries <35, 35 to 54 or 55 to 74 μm in diameter were missing, with the greatest decrease occurring among the smallest ducts; (iii) bile duct loss was seen in the absence of significant large vessel chronic obliterative arteriopathy, and (iv) the severity of arteriole and bile duct loss, as well as the size of the vanished ducts, was directly proportional to the degree of chronic obliterative arteriopathy. Furthermore, the size of the “vanished” bile ducts in liver allografts appeared to differ from the size of ducts destroyed in primary biliary cirrhosis. These studies offer indirect, but suggestive proof that two mechanisms are operative in the bile duct loss seen in chronic rejection: direct lymphocytotoxicity and ischemic damage.
Applied Physics Letters, 2009
Inspired by the natural design of bacterial flagella, we report artificial bacterial flagella ͑AB... more Inspired by the natural design of bacterial flagella, we report artificial bacterial flagella ͑ABF͒ that have a comparable shape and size to their organic counterparts and can swim in a controllable fashion using weak applied magnetic fields. The helical swimmer consists of a helical tail resembling the dimensions of a natural flagellum and a thin soft-magnetic "head" on one end. The swimming locomotion of ABF is precisely controlled by three orthogonal electromagnetic coil pairs. Microsphere manipulation is performed, and the thrust force generated by an ABF is analyzed. ABF swimmers represent the first demonstration of microscopic artificial swimmers that use helical propulsion. Self-propelled devices such as these are of interest in fundamental research and for biomedical applications.
School Pride: "Playing a contributing role in maintaining and improving all aspects of a school's... more School Pride: "Playing a contributing role in maintaining and improving all aspects of a school's environment, programs and activities." We have been holding many discussions with our middle school students over the past couple of months regarding school pride. Through these discussions, we are attempting to educate our students on what school pride is and what it looks like. School pride can extend itself from having great spirit, voice and support at a sporting event, to picking up a gum wrapper in the school hallway. Obviously, school pride encompasses many, many things. However, one thing we do know at Wahoo Middle School is that it is a priority. We have been challenging our students, and will continue to challenge them regarding school pride. We have high expectations for our students and the care and pride they have within our school building. We expect that our students keep their locker areas, classroom areas, and lunch room areas clean and neat. In addition, it is our expectation that our students show school pride and respect by following our guidelines regarding school dress. These are just two examples of topics being discussed within our school building. As a parent, please encourage your child to take great care and pride in their school. Together, we can insure that the Wahoo Middle School is truly a GREAT place to learn!!!
Digestive Diseases and Sciences, 1990
The effect of ranitidine administration upon the hepatotoxic effect produced by a multidose aceta... more The effect of ranitidine administration upon the hepatotoxic effect produced by a multidose acetaminophen administration regimen was examined. Seventy-two dogs received three subcutaneous injections of acetaminophen (750, 200, 200 mg/kg body wt) in DMSO (600 mg/ml) at time zero, 9 hr later, and 24 hr after the first dose. Ten control animals (group I) were not given ranitidine, the remaining 62 dogs received an intramus-cular injection of ranitidine 30 min before each acetaminophen dose. Three different doses of ranitidine were used (mg/kg body wt): 50 mg, group II (33 dogs); 75 mg, group III (14 dogs); 120 mg, group IV (15 dogs). Ranitidine reduced the expected acetaminophen-induced hepatoxicity in a dose-response manner. Moreover, a significant correlation was found between the ranitidine dose and the survival rate, as evidenced by transaminase levels in the serum and histology of the liver. This model of fulminant hepatic failure induced by acetaminophen and its modulation with ranitidine provides clinical investigators with a research tool that will be useful in the future investigation of putative medical and surgical therapies being investigated for use in the clinical management of fulminant hepatic failure. Because of the size of the animal used in this model, frequent and serial analyses of blood and liver were available for study to determine the effect of therapy within a given animal as opposed to within groups of animals.