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Papers by priya jaswani
Journal of Evolution of Medical and Dental Sciences, 2018
BACKGROUND The most frequent hypochromic microcytic anaemias are iron deficiency anaemia and β-th... more BACKGROUND The most frequent hypochromic microcytic anaemias are iron deficiency anaemia and β-thalassemia. It is estimated that about 50% of the world's population with-Thalassemia trait are in Southeast Asia. Thalassemia traits are commonly misdiagnosed and treated as iron deficiency anaemias, in which iron is not required. It causes both economic and health burden to the patient. The excess iron has toxic effects on the body. The purpose of using indices to discriminate anaemia is to detect subjects who have a high probability of requiring appropriate follow-up and to reduce unnecessary investigative costs. Aims and Objectives-1. To study red blood cell indices and peripheral smear examination in microcytic hypochromic anaemia. 2. Estimation of HbA2 levels (Using Haemoglobin Electrophoresis/ HPLC) and Serum ferritin levels of all cases and confirmation of β-Thalassemia trait and Iron deficiency anaemia cases. 3. To evaluate the diagnostic value of various RBC indices in diagnosing β-Thalassemia trait and Iron deficiency anaemia. 4. To evaluate the Sehgal index and compare it to existing complete blood count based indices.
International Journal of Research in Medical Sciences, Aug 25, 2018
Background: Analysis of ascitic fluid and peritoneal washing cytology serves as a useful predicto... more Background: Analysis of ascitic fluid and peritoneal washing cytology serves as a useful predictor of ovarian surface involvement and peritoneal metastasis even in the absence of clinical omental spread. The aim of the current study is to correlate peritoneal cytology with various histologic features of ovarian cancers. Methods: It is a retrospective study. A total of 30 cases of ovarian neoplasms were included in the study. Results of peritoneal cytology were correlated with various histologic features of ovarian tumors including histologic type, grade, tumor size, capsular invasion, and omental metastasis, using chi-square test. A p value of <0.05 was considered as statistically significant. Results: Out of the 30 cases of ovarian tumors involved in the study, twenty-five cases were surface epithelial tumors, two sex-cord stromal tumors, one germ cell tumor, one primary ovarian lymphoma and one metastatic carcinoma. Capsular invasion was seen in 56.3 % of the cases, and omental metastasis in 46.6 % of the cases. A significant positive correlation was seen between positive peritoneal cytology and capsular invasion and omental metastasis with a p value of <0.001. Conclusions: Peritoneal fluid cytology is an indicator of peritoneal metastasis. Positive cytology also correlates with capsular invasion and histologic type in ovarian tumors. Therefore, it should always be used as an adjunctive tool in the surgical management of ovarian tumors.
Journal of Evolution of Medical and Dental Sciences, 2018
BACKGROUND The most frequent hypochromic microcytic anaemias are iron deficiency anaemia and β-th... more BACKGROUND The most frequent hypochromic microcytic anaemias are iron deficiency anaemia and β-thalassemia. It is estimated that about 50% of the world's population with-Thalassemia trait are in Southeast Asia. Thalassemia traits are commonly misdiagnosed and treated as iron deficiency anaemias, in which iron is not required. It causes both economic and health burden to the patient. The excess iron has toxic effects on the body. The purpose of using indices to discriminate anaemia is to detect subjects who have a high probability of requiring appropriate follow-up and to reduce unnecessary investigative costs. Aims and Objectives-1. To study red blood cell indices and peripheral smear examination in microcytic hypochromic anaemia. 2. Estimation of HbA2 levels (Using Haemoglobin Electrophoresis/ HPLC) and Serum ferritin levels of all cases and confirmation of β-Thalassemia trait and Iron deficiency anaemia cases. 3. To evaluate the diagnostic value of various RBC indices in diagnosing β-Thalassemia trait and Iron deficiency anaemia. 4. To evaluate the Sehgal index and compare it to existing complete blood count based indices.
International Journal of Research in Medical Sciences, Aug 25, 2018
Background: Analysis of ascitic fluid and peritoneal washing cytology serves as a useful predicto... more Background: Analysis of ascitic fluid and peritoneal washing cytology serves as a useful predictor of ovarian surface involvement and peritoneal metastasis even in the absence of clinical omental spread. The aim of the current study is to correlate peritoneal cytology with various histologic features of ovarian cancers. Methods: It is a retrospective study. A total of 30 cases of ovarian neoplasms were included in the study. Results of peritoneal cytology were correlated with various histologic features of ovarian tumors including histologic type, grade, tumor size, capsular invasion, and omental metastasis, using chi-square test. A p value of <0.05 was considered as statistically significant. Results: Out of the 30 cases of ovarian tumors involved in the study, twenty-five cases were surface epithelial tumors, two sex-cord stromal tumors, one germ cell tumor, one primary ovarian lymphoma and one metastatic carcinoma. Capsular invasion was seen in 56.3 % of the cases, and omental metastasis in 46.6 % of the cases. A significant positive correlation was seen between positive peritoneal cytology and capsular invasion and omental metastasis with a p value of <0.001. Conclusions: Peritoneal fluid cytology is an indicator of peritoneal metastasis. Positive cytology also correlates with capsular invasion and histologic type in ovarian tumors. Therefore, it should always be used as an adjunctive tool in the surgical management of ovarian tumors.