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Papers by jorge luis henriquez galvez
Motivation. The main goal of the present work is selecting new cytostatic lead compounds through ... more Motivation. The main goal of the present work is selecting new cytostatic lead compounds through molecular topology. This is particularly interesting since the finding of new therapeutic alternatives for cancer continues to be a very difficult task as demonstrated by the low number of lead drugs approved by the international agencies in the later years in this field. Method. Molecular
Combinatorial Chemistry &# 38; …, 2006
Abstract: Virtual filtering and screening of combinatorial libraries have recently gained attenti... more Abstract: Virtual filtering and screening of combinatorial libraries have recently gained attention as methods complementing the high-throughput screening and combinatorial chemistry. These chemoinformatic techniques rely heavily on quantitative structure-activity relationship ...
Motivation. The main goal of the present work is selecting new cytostatic lead compounds through ... more Motivation. The main goal of the present work is selecting new cytostatic lead compounds through molecular topology. This is particularly interesting since the finding of new therapeutic alternatives for cancer continues to be a very difficult task as demonstrated by the low number of lead drugs approved by the international agencies in the later years in this field. Method. Molecular
Combinatorial Chemistry &# 38; …, 2006
Abstract: Virtual filtering and screening of combinatorial libraries have recently gained attenti... more Abstract: Virtual filtering and screening of combinatorial libraries have recently gained attention as methods complementing the high-throughput screening and combinatorial chemistry. These chemoinformatic techniques rely heavily on quantitative structure-activity relationship ...