k bhaskar - Academia.edu (original) (raw)
Papers by k bhaskar
Indian Journal of Medical and Paediatric Oncology
In this era of targeted therapy, it is important to distinguish the various subtypes of nonsmall ... more In this era of targeted therapy, it is important to distinguish the various subtypes of nonsmall cell lung carcinoma (NSCC). Diagnosis based on morphology alone is challenging in poorly differentiated carcinomas and core biopsies. Immunohistochemistry (IHC) helps in specifying the lineage for the subtype of NSCC. Till date, p63 is the most frequently used and sensitive marker for squamous cell carcinoma (SQCC). However, it is not specific and stains a subset of adenocarcinoma (ADC). Thus, a more reliable and specific marker is required for the diagnosis of SQCC.The objective of the study was to validate the diagnostic utility of p40 over p63 in differentiating pulmonary SQCC from ADC and NSCC-not otherwise specified (NOS).A total of 123 cases of NSCC were initially reviewed and subtyped blinded to the results of IHC. This was followed by a review of IHC slides which included p63, p40, thyroid transcription factor 1, Napsin-A, cytokeratin (CK) 5/6, and CK7.There were 64 ADC, 19 SQCC,...
This paper presents a new generation of Green energy being renewable can be generated in many ind... more This paper presents a new generation of Green energy being renewable can be generated in many industries where there is continuous source of vibrations. The cantilever beam is used as a source of vibration for power generation. MEMS sensor placed on the beam will convert the mechanical energy generated from the movement of the beam into electrical energy. The output of MEMS is given to the ADC for analog to digital conversion and then to microcontroller in order to monitor the value of energy generated. The obtained energy is boosted up using a DC-DC booster. The output of the DC-DC booster is stored in a storage device. The obtained energy is used to power the low power electronic devices and wireless sensor nodes in industries. The voltage control is provided by the microcontroller.
The objective of this paper is to present the experimental results of Vapour Absorption Refrigera... more The objective of this paper is to present the experimental results of Vapour Absorption Refrigeration System of 1kW capacity using R134a-DMAC as the working fluids. The system is designed using hot water as heat source for a heat input of 4 kW at various generator temperatures and tested at sink temperature of 25 o C. An average COP of 0.34 was obtained under the above test conditions. The study reveals the feasibility of using environmental friendly R134a-DMAC as working fluids in the absorption system using low potential heat sources for the Heating, Ventilation, Air Conditioning and Refrigeration applications. The hot water source can be replaced with solar panel heater to harness solar energy.
Purpose: To formulate extended-release tablets of diclofenac sodium based on ispaghula husk Metho... more Purpose: To formulate extended-release tablets of diclofenac sodium based on ispaghula husk Methods: Tablets with varying proportions of diclofenac sodium and ispaghula husk were formulated by wet granulation technique at a fixed compression force of 10 kN. The formulated tablets were evaluated for physicochemical parameters as well as by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and x-ray diffraction (XRD). Results: Content uniformity, weight variation, thickness and friability of the formulated tablets were within acceptable limits. The hardness of the tablet decreased from 5.4 to 4.2 kg/cm2 with increasing quantity of ispaghula husk in the formulation. In contrast, disintegration time increased from 12 to 70 min with increasing amount of husk. Tablets formulated with 1:0.25 and 1:0.5 drug/husk ratio failed to extend drug release whereas tablets prepared with 1:0.75 and 1:1 ratio extended release up to 5 and 6 h, respectively. FTIR, DS...
IOP Conference Series: Materials Science and Engineering, 2021
The global automotive industry is faced with the task of reducing global greenhouse gas emissions... more The global automotive industry is faced with the task of reducing global greenhouse gas emissions generated by vehicle exhaust. Heavy machinery like trucks, trailers, off-road vehicles, etc. powered by the diesel engines. These vehicles emit large quantities of NOx and smoke emissions. The simultaneous reduction of both emissions is the key challenge for the automotive industry. Burning a homogeneous charge at relatively low temperature seems to be the means to control both the emissions simultaneously. In this experimental study, the combustion, performance and emissions characteristics of a premixed charge compression Ignition Engine (PCCI) with ethanol injected in the intake manifold of the engine along with biodiesel (Palm oil methyl ester) injected directly into the combustion chamber. The experiments were carried out in a four-stroke, single cylinder vertical water cooled, constant speed diesel engine with the range of 10- 30% premixed ethanol fuel from no load to full load co...
Indian Journal of Respiratory Care, 2021
The objective of this study is to evaluate the diagnostic yield of endobronchial biopsy in variou... more The objective of this study is to evaluate the diagnostic yield of endobronchial biopsy in various neoplastic and nonneoplastic lung lesions. Patients and Methods: A total number of 204 consecutive cases of fiberoptic bronchoscopic-guided endobronchial biopsies was analyzed. The bronchial wash (BW) samples collected simultaneously during the biopsy were correlated with final histopathology diagnosis. Results: The bronchoscopic findings mainly included endobronchial mass, increased mucosal vascularity, and mucosal irregularities. Of the 184 adequate biopsy samples, 32.3% were neoplastic, 20.5% nonneoplastic, and remaining 41.3% revealed normal histology. The nonneoplastic lesions included mainly nonspecific inflammation, granulomatous inflammation followed by few cases of squamous metaplasia, one case each of tracheobronchopathia osteochondroplastica, mycobacterium spindle cell pseudotumor, and cytomegalovirus infection. Among the malignant tumors, adenocarcinoma (ADC) was the most common followed by squamous cell carcinoma (SQCC) and non-small cell carcinoma-not otherwise specified. On immunohistochemistry, Napsin-A showed better sensitivity than thyroid transcription factor-1 for ADC. P40 was found to be most sensitive and specific markers for SQCC. Neuroendocrine tumors included seven small cell carcinoma and three carcinoids. Both chromogranin and synaptophysin were found to be equally sensitive neuroendocrine markers. The bronchoscopically normal airways mostly revealed normal histology with few showing mild nonspecific inflammation. On the contrary, all except one case of neoplasm had mass lesions on bronchoscopy. Conclusion: EBB provides sufficient tissue for morphological and immunohistochemical characterization of malignant lesions. BW cytology has poor concordance with EBB in the diagnosis of malignancies with nearly 70% cases being false negative.
An attempt has been made to charge the battery with P-V module obtained from a company. Initially... more An attempt has been made to charge the battery with P-V module obtained from a company. Initially P-V characteristics have been carried out for five different solar intensities and for four different temperatures. P-V characteristics have also been done for five different Shunt resistances and three different series resistance which will form the basis of equivalent circuit of a solar panel charger used to charge the battery circuit. Three different modes of charging the battery have also been tried. Results are presented in this communication.
In this paper, we study to reduce network traffic cost for virtually any Map Reduce job by develo... more In this paper, we study to reduce network traffic cost for virtually any Map Reduce job by developing a manuscript intermediate data partition plan. In addition, we with each other consider the aggregator positioning problem, where each aggregator helps to reduce merged traffic from multiple map tasks. However, some attempts are actually made to enhance the performance of Map Reduce jobs, they ignore the network traffic created inside the shuffle phase, which plays a crucial role in performance enhancement. The Map Reduce programming model simplifies large-scale computer on commodity cluster by exploiting parallel map tasks minimizing tasks. Finally, extensive simulation results show our plans can significantly reduce network traffic cost under both offline an internet-based-based cases. Typically, a hash function enables you to partition intermediate data among reduce tasks, which, however, is not traffic-efficient because network topology and understanding size connected with each...
2020 IEEE International Power and Renewable Energy Conference, 2020
This paper gives the theoretical idea about energy recovery method from unused heat energy produc... more This paper gives the theoretical idea about energy recovery method from unused heat energy produced by internal combustion engine(IC engine) and electrical motors in hybrid electrical vehicles (HEV). This heat energy converts again into electrical energy to charge the separate battery source for auxiliary loads like headlights, indicators, air-conditioners, mobile adapters, and self-ignition of the electrical vehicle (EV). These loads consumes approximately 500watts of energy according to their utilization, this rating is around 5-15% of overall electrical vehicle’s (EV) capacity. This paper describes about the conversion of unused heat energy into electric energy by using Peltier Panel for auxiliary load applications while hybrid electrical vehicle (HEV) is running. This method increases the efficiency of electric motors at the same time increases the kilometres per charge of electrical vehicle (EV).
In today's technically advanced world, autonomous systems are gaining rapid popularity. The g... more In today's technically advanced world, autonomous systems are gaining rapid popularity. The goal of this project was to develop a ploughing vehicle usually like tractors used to plough a field and it can be controlled automatically or manually through PC. This vehicle has a combination of wireless camera integrate in such a way, so as to provide simultaneous data acquisition and data transmission to the remote user through a RF transceiver.
Complexes of oxovanadium(lV) with N,N' -ethylene-bis-(2-aminobenzamide) [EBAB], N,N ' -pr... more Complexes of oxovanadium(lV) with N,N' -ethylene-bis-(2-aminobenzamide) [EBAB], N,N ' -propylene-bis-(2ami nobenzamide) [PBAB], N.N' -(o-phenylene)-bis-(2-aminobenzamide) [PhBAB], N,N' -ethylene-bis-(3-carboxypropena mide) [EBCP], N,N' -propylene-bis-(3-carboxypropenamide) [PBCP]- and 1-(2'-hydroxyphenyl)-3-phenyl-I ,3-propanedione [HPPPD] ha ve bee n prepared and characterized by chemical analyses, molar conductivity, magnetic susceptibility meas urements. thermal studies, IR. electroni c and ESR spectra. Further, de-oxygenation react ions of these complexes with thi onyl ch lorid e yie ld vanadium(lV) complexes. The spectral data reveal that oxovanadium(lV) complexes are square py ramidal while the va nadium(lV) complexes are octahedral. The chemistry of oxocations I has been very interesting because the metal-oxygen multiple bond in them could be used as an internal molecular probe to understand more about the nature of the metal ligand bonds as the M-L...
International Journal of Drug Delivery, 2012
The main aim of pharmaceutical research is steadily shifted from the development of new chemical ... more The main aim of pharmaceutical research is steadily shifted from the development of new chemical entities to the development of novel drug delivery system of existing drug molecule to maximize their effectiveness in terms of therapeutic action, patent protection, patient compliance and reduced adverse effects. In the recent years the interest is growing to develop a drug delivery system with the use of a mucoadhesive polymer that will attach to related tissue or to the surface coating of the tissue for targeting various absorptive mucosa such as ocular, nasal, pulmonary, buccal, vaginal, etc. This system of drug delivery is called mucoadhesive drug delivery system. The buccal region of oral cavity is an attractive target for administration of drug of choice. Buccal drug delivery involves the administration of desired drug through the buccal mucosal lining of the oral cavity. Other than the common advantages of novel drug delivery systems, buccal mucosa has several specific advan...
Pneumonia is defined as an inflammation of the pulmonary parenchyma caused by an infectious agent... more Pneumonia is defined as an inflammation of the pulmonary parenchyma caused by an infectious agent. The clinical syndrome of pneumonia includes fever or hypothermia, sweats, rigors, or chills, pulmonary symptoms such as cough, sputum production, dyspnea, pleurisy, or pulmonary lesions observed on radiographic examination. Despite being the cause of significant morbidity and mortality, pneumonia is often misdiagnosed, mistreated, and underestimated. Pneumonia is a common cause of infection-related mortality and is one
Materials Today: Proceedings, 2021
Abstract Partially pre-blended compression ignition engine reduces the discharge of oxides of nit... more Abstract Partially pre-blended compression ignition engine reduces the discharge of oxides of nitrogen and soot. The aim of this research is to study the combustion and emission parameters of hybrid mode compression ignition (HBMCI) at different hybrid ratios. In this system, the percentage of fuel is introduced in the intake manifold is varied according to hybrid ratios. The remaining part of the fuel is injected straight into combustion chamber prior to the end of the compression stroke to trigger the combustion event. The pre-blended charge is burnt in the cylinder along with the fuel directly injected into the cylinder by a conventional injection system. The brake thermal efficiency at rated power output in Hybrid Mode Diesel-JOME (HBMDJ Mode) is observed from 26.8% to 21.6% and in Hybrid Mode Diesel-FOME (HBMDF Mode) is observed from 26.4% to 21.4%, when the hybrid ratio changed from 0.25 to 0.75, compared to 28.4% in diesel mode. The hybrid ratio of 0.25 is observed to be optimum in both HBMDJ and HBMDF. At this hybrid ratio, decrease in brake thermal efficiency is marginal compared to diesel mode. Significant reduction in soot emission is also found than that of diesel mode. From the above investigation, it can be seen than HBMDJ mode was better than HBMDF mode by comparing the performance, combustion and emission characteristics.
Materials Today: Proceedings, 2021
Abstract Self-Healing Materials (SHM) today plays a major role in the field of study and research... more Abstract Self-Healing Materials (SHM) today plays a major role in the field of study and research in materials. Alternatively SHM can be termed as autonomous healing materials, automatics healing materials. These are the type of materials where they can heal themselves, from any impact that causes a dislocation or irregular changes in structure. This paper discusses different types of Self-Healing Materials in depth and application of SHM in Concretes. This paper also explains various aspect of SHM like usage of the capsule, mechanical strength, thermal analysis and structures of SHM. This paper further discusses several practical applications of SHM in daily usage as composites, polymers, fiber reinforced composites, coatings, ceramics, polyurethane foam coatings and matrices.
Chemical Data Collections, 2021
Materials Today: Proceedings, 2020
Rapid depletion of fossil fuel and increased demand for petroleum products in energy and transpor... more Rapid depletion of fossil fuel and increased demand for petroleum products in energy and transportation sector motivated the researchers to find a substitution for petroleum diesel. Biodiesel is one among the alternate to this crisis. Biodiesel is a combined mixture of fatty acid alkyl esters obtained by the reaction of triglycerides of vegetable or animal origin with alcohol in the presence of a catalyst. The fatty acid profile influences the overall properties of the biodiesel. The properties of individual fatty acid depend on the occurrence of double bonds, fatty acid chain length and branching. Better understanding of the fatty acid composition and correlating the fuel properties is of utmost importance in improving the optimal performance. In the present study, feedstocks of Cymbopogon citratus, Pinus sylvestris and Syzygium cumini is analysed for its fatty acid composition study using Gas Chromatography assisted with mass spectrometry. Based on GC-MS Analysis, fifteen types of fatty acids in Cymbopogon citratus, Pinus sylvestris and Syzygium cumini oil methyl esters were analysed and defined; all these esters are amalgamations of saturated and unsaturated fatty acids. The variation in fatty acid compositions affects the properties of the esters. GC-MS synthesis showed that methyl, ethyl esters free from dirt for the three feedstocks. Few impurities like mainly mono-, di-and triglycerides were found.
Materials Today: Proceedings, 2020
Indian Journal of Medical and Paediatric Oncology
In this era of targeted therapy, it is important to distinguish the various subtypes of nonsmall ... more In this era of targeted therapy, it is important to distinguish the various subtypes of nonsmall cell lung carcinoma (NSCC). Diagnosis based on morphology alone is challenging in poorly differentiated carcinomas and core biopsies. Immunohistochemistry (IHC) helps in specifying the lineage for the subtype of NSCC. Till date, p63 is the most frequently used and sensitive marker for squamous cell carcinoma (SQCC). However, it is not specific and stains a subset of adenocarcinoma (ADC). Thus, a more reliable and specific marker is required for the diagnosis of SQCC.The objective of the study was to validate the diagnostic utility of p40 over p63 in differentiating pulmonary SQCC from ADC and NSCC-not otherwise specified (NOS).A total of 123 cases of NSCC were initially reviewed and subtyped blinded to the results of IHC. This was followed by a review of IHC slides which included p63, p40, thyroid transcription factor 1, Napsin-A, cytokeratin (CK) 5/6, and CK7.There were 64 ADC, 19 SQCC,...
This paper presents a new generation of Green energy being renewable can be generated in many ind... more This paper presents a new generation of Green energy being renewable can be generated in many industries where there is continuous source of vibrations. The cantilever beam is used as a source of vibration for power generation. MEMS sensor placed on the beam will convert the mechanical energy generated from the movement of the beam into electrical energy. The output of MEMS is given to the ADC for analog to digital conversion and then to microcontroller in order to monitor the value of energy generated. The obtained energy is boosted up using a DC-DC booster. The output of the DC-DC booster is stored in a storage device. The obtained energy is used to power the low power electronic devices and wireless sensor nodes in industries. The voltage control is provided by the microcontroller.
The objective of this paper is to present the experimental results of Vapour Absorption Refrigera... more The objective of this paper is to present the experimental results of Vapour Absorption Refrigeration System of 1kW capacity using R134a-DMAC as the working fluids. The system is designed using hot water as heat source for a heat input of 4 kW at various generator temperatures and tested at sink temperature of 25 o C. An average COP of 0.34 was obtained under the above test conditions. The study reveals the feasibility of using environmental friendly R134a-DMAC as working fluids in the absorption system using low potential heat sources for the Heating, Ventilation, Air Conditioning and Refrigeration applications. The hot water source can be replaced with solar panel heater to harness solar energy.
Purpose: To formulate extended-release tablets of diclofenac sodium based on ispaghula husk Metho... more Purpose: To formulate extended-release tablets of diclofenac sodium based on ispaghula husk Methods: Tablets with varying proportions of diclofenac sodium and ispaghula husk were formulated by wet granulation technique at a fixed compression force of 10 kN. The formulated tablets were evaluated for physicochemical parameters as well as by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and x-ray diffraction (XRD). Results: Content uniformity, weight variation, thickness and friability of the formulated tablets were within acceptable limits. The hardness of the tablet decreased from 5.4 to 4.2 kg/cm2 with increasing quantity of ispaghula husk in the formulation. In contrast, disintegration time increased from 12 to 70 min with increasing amount of husk. Tablets formulated with 1:0.25 and 1:0.5 drug/husk ratio failed to extend drug release whereas tablets prepared with 1:0.75 and 1:1 ratio extended release up to 5 and 6 h, respectively. FTIR, DS...
IOP Conference Series: Materials Science and Engineering, 2021
The global automotive industry is faced with the task of reducing global greenhouse gas emissions... more The global automotive industry is faced with the task of reducing global greenhouse gas emissions generated by vehicle exhaust. Heavy machinery like trucks, trailers, off-road vehicles, etc. powered by the diesel engines. These vehicles emit large quantities of NOx and smoke emissions. The simultaneous reduction of both emissions is the key challenge for the automotive industry. Burning a homogeneous charge at relatively low temperature seems to be the means to control both the emissions simultaneously. In this experimental study, the combustion, performance and emissions characteristics of a premixed charge compression Ignition Engine (PCCI) with ethanol injected in the intake manifold of the engine along with biodiesel (Palm oil methyl ester) injected directly into the combustion chamber. The experiments were carried out in a four-stroke, single cylinder vertical water cooled, constant speed diesel engine with the range of 10- 30% premixed ethanol fuel from no load to full load co...
Indian Journal of Respiratory Care, 2021
The objective of this study is to evaluate the diagnostic yield of endobronchial biopsy in variou... more The objective of this study is to evaluate the diagnostic yield of endobronchial biopsy in various neoplastic and nonneoplastic lung lesions. Patients and Methods: A total number of 204 consecutive cases of fiberoptic bronchoscopic-guided endobronchial biopsies was analyzed. The bronchial wash (BW) samples collected simultaneously during the biopsy were correlated with final histopathology diagnosis. Results: The bronchoscopic findings mainly included endobronchial mass, increased mucosal vascularity, and mucosal irregularities. Of the 184 adequate biopsy samples, 32.3% were neoplastic, 20.5% nonneoplastic, and remaining 41.3% revealed normal histology. The nonneoplastic lesions included mainly nonspecific inflammation, granulomatous inflammation followed by few cases of squamous metaplasia, one case each of tracheobronchopathia osteochondroplastica, mycobacterium spindle cell pseudotumor, and cytomegalovirus infection. Among the malignant tumors, adenocarcinoma (ADC) was the most common followed by squamous cell carcinoma (SQCC) and non-small cell carcinoma-not otherwise specified. On immunohistochemistry, Napsin-A showed better sensitivity than thyroid transcription factor-1 for ADC. P40 was found to be most sensitive and specific markers for SQCC. Neuroendocrine tumors included seven small cell carcinoma and three carcinoids. Both chromogranin and synaptophysin were found to be equally sensitive neuroendocrine markers. The bronchoscopically normal airways mostly revealed normal histology with few showing mild nonspecific inflammation. On the contrary, all except one case of neoplasm had mass lesions on bronchoscopy. Conclusion: EBB provides sufficient tissue for morphological and immunohistochemical characterization of malignant lesions. BW cytology has poor concordance with EBB in the diagnosis of malignancies with nearly 70% cases being false negative.
An attempt has been made to charge the battery with P-V module obtained from a company. Initially... more An attempt has been made to charge the battery with P-V module obtained from a company. Initially P-V characteristics have been carried out for five different solar intensities and for four different temperatures. P-V characteristics have also been done for five different Shunt resistances and three different series resistance which will form the basis of equivalent circuit of a solar panel charger used to charge the battery circuit. Three different modes of charging the battery have also been tried. Results are presented in this communication.
In this paper, we study to reduce network traffic cost for virtually any Map Reduce job by develo... more In this paper, we study to reduce network traffic cost for virtually any Map Reduce job by developing a manuscript intermediate data partition plan. In addition, we with each other consider the aggregator positioning problem, where each aggregator helps to reduce merged traffic from multiple map tasks. However, some attempts are actually made to enhance the performance of Map Reduce jobs, they ignore the network traffic created inside the shuffle phase, which plays a crucial role in performance enhancement. The Map Reduce programming model simplifies large-scale computer on commodity cluster by exploiting parallel map tasks minimizing tasks. Finally, extensive simulation results show our plans can significantly reduce network traffic cost under both offline an internet-based-based cases. Typically, a hash function enables you to partition intermediate data among reduce tasks, which, however, is not traffic-efficient because network topology and understanding size connected with each...
2020 IEEE International Power and Renewable Energy Conference, 2020
This paper gives the theoretical idea about energy recovery method from unused heat energy produc... more This paper gives the theoretical idea about energy recovery method from unused heat energy produced by internal combustion engine(IC engine) and electrical motors in hybrid electrical vehicles (HEV). This heat energy converts again into electrical energy to charge the separate battery source for auxiliary loads like headlights, indicators, air-conditioners, mobile adapters, and self-ignition of the electrical vehicle (EV). These loads consumes approximately 500watts of energy according to their utilization, this rating is around 5-15% of overall electrical vehicle’s (EV) capacity. This paper describes about the conversion of unused heat energy into electric energy by using Peltier Panel for auxiliary load applications while hybrid electrical vehicle (HEV) is running. This method increases the efficiency of electric motors at the same time increases the kilometres per charge of electrical vehicle (EV).
In today's technically advanced world, autonomous systems are gaining rapid popularity. The g... more In today's technically advanced world, autonomous systems are gaining rapid popularity. The goal of this project was to develop a ploughing vehicle usually like tractors used to plough a field and it can be controlled automatically or manually through PC. This vehicle has a combination of wireless camera integrate in such a way, so as to provide simultaneous data acquisition and data transmission to the remote user through a RF transceiver.
Complexes of oxovanadium(lV) with N,N' -ethylene-bis-(2-aminobenzamide) [EBAB], N,N ' -pr... more Complexes of oxovanadium(lV) with N,N' -ethylene-bis-(2-aminobenzamide) [EBAB], N,N ' -propylene-bis-(2ami nobenzamide) [PBAB], N.N' -(o-phenylene)-bis-(2-aminobenzamide) [PhBAB], N,N' -ethylene-bis-(3-carboxypropena mide) [EBCP], N,N' -propylene-bis-(3-carboxypropenamide) [PBCP]- and 1-(2'-hydroxyphenyl)-3-phenyl-I ,3-propanedione [HPPPD] ha ve bee n prepared and characterized by chemical analyses, molar conductivity, magnetic susceptibility meas urements. thermal studies, IR. electroni c and ESR spectra. Further, de-oxygenation react ions of these complexes with thi onyl ch lorid e yie ld vanadium(lV) complexes. The spectral data reveal that oxovanadium(lV) complexes are square py ramidal while the va nadium(lV) complexes are octahedral. The chemistry of oxocations I has been very interesting because the metal-oxygen multiple bond in them could be used as an internal molecular probe to understand more about the nature of the metal ligand bonds as the M-L...
International Journal of Drug Delivery, 2012
The main aim of pharmaceutical research is steadily shifted from the development of new chemical ... more The main aim of pharmaceutical research is steadily shifted from the development of new chemical entities to the development of novel drug delivery system of existing drug molecule to maximize their effectiveness in terms of therapeutic action, patent protection, patient compliance and reduced adverse effects. In the recent years the interest is growing to develop a drug delivery system with the use of a mucoadhesive polymer that will attach to related tissue or to the surface coating of the tissue for targeting various absorptive mucosa such as ocular, nasal, pulmonary, buccal, vaginal, etc. This system of drug delivery is called mucoadhesive drug delivery system. The buccal region of oral cavity is an attractive target for administration of drug of choice. Buccal drug delivery involves the administration of desired drug through the buccal mucosal lining of the oral cavity. Other than the common advantages of novel drug delivery systems, buccal mucosa has several specific advan...
Pneumonia is defined as an inflammation of the pulmonary parenchyma caused by an infectious agent... more Pneumonia is defined as an inflammation of the pulmonary parenchyma caused by an infectious agent. The clinical syndrome of pneumonia includes fever or hypothermia, sweats, rigors, or chills, pulmonary symptoms such as cough, sputum production, dyspnea, pleurisy, or pulmonary lesions observed on radiographic examination. Despite being the cause of significant morbidity and mortality, pneumonia is often misdiagnosed, mistreated, and underestimated. Pneumonia is a common cause of infection-related mortality and is one
Materials Today: Proceedings, 2021
Abstract Partially pre-blended compression ignition engine reduces the discharge of oxides of nit... more Abstract Partially pre-blended compression ignition engine reduces the discharge of oxides of nitrogen and soot. The aim of this research is to study the combustion and emission parameters of hybrid mode compression ignition (HBMCI) at different hybrid ratios. In this system, the percentage of fuel is introduced in the intake manifold is varied according to hybrid ratios. The remaining part of the fuel is injected straight into combustion chamber prior to the end of the compression stroke to trigger the combustion event. The pre-blended charge is burnt in the cylinder along with the fuel directly injected into the cylinder by a conventional injection system. The brake thermal efficiency at rated power output in Hybrid Mode Diesel-JOME (HBMDJ Mode) is observed from 26.8% to 21.6% and in Hybrid Mode Diesel-FOME (HBMDF Mode) is observed from 26.4% to 21.4%, when the hybrid ratio changed from 0.25 to 0.75, compared to 28.4% in diesel mode. The hybrid ratio of 0.25 is observed to be optimum in both HBMDJ and HBMDF. At this hybrid ratio, decrease in brake thermal efficiency is marginal compared to diesel mode. Significant reduction in soot emission is also found than that of diesel mode. From the above investigation, it can be seen than HBMDJ mode was better than HBMDF mode by comparing the performance, combustion and emission characteristics.
Materials Today: Proceedings, 2021
Abstract Self-Healing Materials (SHM) today plays a major role in the field of study and research... more Abstract Self-Healing Materials (SHM) today plays a major role in the field of study and research in materials. Alternatively SHM can be termed as autonomous healing materials, automatics healing materials. These are the type of materials where they can heal themselves, from any impact that causes a dislocation or irregular changes in structure. This paper discusses different types of Self-Healing Materials in depth and application of SHM in Concretes. This paper also explains various aspect of SHM like usage of the capsule, mechanical strength, thermal analysis and structures of SHM. This paper further discusses several practical applications of SHM in daily usage as composites, polymers, fiber reinforced composites, coatings, ceramics, polyurethane foam coatings and matrices.
Chemical Data Collections, 2021
Materials Today: Proceedings, 2020
Rapid depletion of fossil fuel and increased demand for petroleum products in energy and transpor... more Rapid depletion of fossil fuel and increased demand for petroleum products in energy and transportation sector motivated the researchers to find a substitution for petroleum diesel. Biodiesel is one among the alternate to this crisis. Biodiesel is a combined mixture of fatty acid alkyl esters obtained by the reaction of triglycerides of vegetable or animal origin with alcohol in the presence of a catalyst. The fatty acid profile influences the overall properties of the biodiesel. The properties of individual fatty acid depend on the occurrence of double bonds, fatty acid chain length and branching. Better understanding of the fatty acid composition and correlating the fuel properties is of utmost importance in improving the optimal performance. In the present study, feedstocks of Cymbopogon citratus, Pinus sylvestris and Syzygium cumini is analysed for its fatty acid composition study using Gas Chromatography assisted with mass spectrometry. Based on GC-MS Analysis, fifteen types of fatty acids in Cymbopogon citratus, Pinus sylvestris and Syzygium cumini oil methyl esters were analysed and defined; all these esters are amalgamations of saturated and unsaturated fatty acids. The variation in fatty acid compositions affects the properties of the esters. GC-MS synthesis showed that methyl, ethyl esters free from dirt for the three feedstocks. Few impurities like mainly mono-, di-and triglycerides were found.
Materials Today: Proceedings, 2020