kemal serez - Academia.edu (original) (raw)
Papers by kemal serez
Pulmoner damar sistemi veya bronfliyal damar sistemine ait Arteriovenöz Malformasyonlar(AVM) hemo... more Pulmoner damar sistemi veya bronfliyal damar sistemine ait Arteriovenöz Malformasyonlar(AVM) hemoptizinin nadir fakat hat›rlanmas› gereken nedenlerinden birisidir. Afla¤›da Gö¤üs Hastal›klar› Klini¤i taraf›ndan bronfliyal a¤aca ait bir kanama saptanmamas› üzerine ileri tetkik amac›yla servisimize yat›r›lan bir hemoptizi vakas› sunulmufltur. Bu vaka vas›tas›yla hemoptizi ay›r›c› tan›s›n› tekrar gözden geçirmek ve nedeni aç›klanamayan hemoptizi vakalar›nda AVM'nin hat›rlanmas› gerekti¤ini vurgulamak istedik.
Diagnostic and Interventional Radiology, 2009
Journal of International Medical Research, 2013
Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethn... more Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethnic groups in Istanbul, Turkey. Methods: Study participants were aged !20 years. Risk factor components for metabolic syndrome were measured and its presence was determined in study participants. Results: The study included 254 Greeks, 273 West Thracians, 275 East Turkistanis and 304 Armenians. The prevalence of metabolic syndrome was significantly different between groups (Greeks, 19.3%; West Thracians, 24.9%; East Turkistanis, 15.3%; Armenians, 20.4%), and increased with age in all groups. Low levels of high-density lipoprotein cholesterol (HDL-C) were found mainly in Greeks (females, 64.5%; males, 61.6%) and West Thracians (females, 75.8%; males, 73.1%). Among East Turkistanis, HDL-C and triglyceride levels were significantly higher compared with the other ethnic groups. Hypertension was the most frequently encountered component of metabolic syndrome in East Turkistanis. Conclusions: The prevalence of metabolic syndrome varied between ethnic groups living in the same geographical location. In Turkey, metabolic syndrome is common. It is important to determine differences between ethnic groups, as this will assist in identifying those at higher risk of developing coronary heart disease.
firattipdergisi.com
Amaç: Alkolik karaciğer sirozunda (AKS) makrositoz sıklığı ve makrositoz ile prognoz arasındaki i... more Amaç: Alkolik karaciğer sirozunda (AKS) makrositoz sıklığı ve makrositoz ile prognoz arasındaki ilişkinin belirlenerek doğruluk, duyarlılık ve özgüllük değerlerinin tespiti amaçlanmıştır. Gereç ve Yöntem: AKS tanısı olan toplam 46 hasta (grup 1) ile Hepatit B ve ...
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2005
BACKGROUND Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic man... more BACKGROUND Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic manifestations. The aim of this study was to determine the prevalence of dermatologic manifestations related to chronic HCV infection in Turkey. MATERIALS AND METHODS 70 patients with chronic HCV infection and 70 healthy volunteers were investigated. They were carefully questioned and skin, mucosa, hair and nails were systematically examined. Laboratory tests for the serum levels of aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transpeptidase, bilirubine and rheumatoid factor were done in all of them. RESULTS The only symptom which was more frequent in patients with chronic HCV infection was generalized pruritus (13 cases, 18.57%). It was observed in three cases of the control group (4.28%), the difference being statistically significant (p:0.01). In the group of patients with chronic HCV infection, three patients were diagnosed as leukocytoclastic vasculitis and thre...
European journal of internal medicine, Nov 1, 2018
Non-thyroidal illness syndrome is characterized by decreased serum free T3 (FT3) level and associ... more Non-thyroidal illness syndrome is characterized by decreased serum free T3 (FT3) level and associates with long term mortality. Serum free T4 (FT4) may affect on mortality with FT3 in course of chronic illness. This study performed to evaluate the association between both decreased FT3 with elevated FT4 levels and mortality risk. This study is a retrospective cohort analysis and consisted up 1164 (571 male, 593 female) patients with a 36 months follow up period. Patients divided into four groups according to thyroid functions. Patients with euthyroidism were in Group A, elevated FT3 in group B, decreased FT3 in group C and both decreased FT3 and elevated FT4 levels in group D. The levels of thyroid hormones and all cause mortality were compared between four groups. Mortality rate was elevated between Groups A and B, A and C, A and D, B and C, B and D, C and D, (p < .001, p < .001, p < .001, p < .001, p < .001, p:0.019, respectively). A multivariate Cox proportional ha...
Background/aims: Pegylated alfa interferon is the only immunomodulatory drug licensed for hepatit... more Background/aims: Pegylated alfa interferon is the only immunomodulatory drug licensed for hepatitis B. We evaluated the safety and tolerability of peginterferon alfa-2a (40KD) in patients with chronic hepatitis B. Materials and Methods: A total of 113 chronic hepatitis B patients under peginterferon alfa-2a (40KD; 180 μg/week) treatment were included in this multicenter, open label, non-interventional study, and 66 patients completed the follow-up period. Vital signs, physical examination and laboratory findings, concomitant medications, and adverse events were recorded. A Quality of Life questionnaire (Short Form-36) was performed twice, at the beginning and at the end of the study. Results: There was no significant difference between initial and last visits in terms of physical examination findings and Short Form-36 scores. A total of 27 adverse events were reported in 15 patients (22.7%), with most of them being mild in intensity (70.4%). The rates of the adverse events were similar in the monotherapy and combination therapy groups (peginterferon alfa-2a + lamivudine, peginterferon alfa-2a + adefovir or peginterferon alfa-2a + entecavir therapy groups), at 23.7% and 14.3%, respectively. The dosage of peginterferon had to be reduced in 3 patients (4.5%) due to thrombocytopenia. Overall patient compliance to treatment was detected as 85.9%. Conclusions: Based on the lack of serious adverse events and absence of impairment in Quality of Life, peginterferon alfa-2a (40KD, 180 μg/week, subcutaneously) treatment for 48 weeks led to a high level of patient compliance and was associated with a high degree of safety and tolerability for the treatment of adult patients with chronic hepatitis B in real-life practice.
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2005
Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic manifestations... more Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic manifestations. The aim of this study was to determine the prevalence of dermatologic manifestations related to chronic HCV infection in Turkey. 70 patients with chronic HCV infection and 70 healthy volunteers were investigated. They were carefully questioned and skin, mucosa, hair and nails were systematically examined. Laboratory tests for the serum levels of aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transpeptidase, bilirubine and rheumatoid factor were done in all of them. The only symptom which was more frequent in patients with chronic HCV infection was generalized pruritus (13 cases, 18.57%). It was observed in three cases of the control group (4.28%), the difference being statistically significant (p:0.01). In the group of patients with chronic HCV infection, three patients were diagnosed as leukocytoclastic vasculitis and three as lichen planus (4.28%). Neither leuko...
Journal of International Medical Research, 2013
Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethn... more Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethnic groups in Istanbul, Turkey. Methods: Study participants were aged !20 years. Risk factor components for metabolic syndrome were measured and its presence was determined in study participants. Results: The study included 254 Greeks, 273 West Thracians, 275 East Turkistanis and 304 Armenians. The prevalence of metabolic syndrome was significantly different between groups (Greeks, 19.3%; West Thracians, 24.9%; East Turkistanis, 15.3%; Armenians, 20.4%), and increased with age in all groups. Low levels of high-density lipoprotein cholesterol (HDL-C) were found mainly in Greeks (females, 64.5%; males, 61.6%) and West Thracians (females, 75.8%; males, 73.1%). Among East Turkistanis, HDL-C and triglyceride levels were significantly higher compared with the other ethnic groups. Hypertension was the most frequently encountered component of metabolic syndrome in East Turkistanis. Conclusions: The prevalence of metabolic syndrome varied between ethnic groups living in the same geographical location. In Turkey, metabolic syndrome is common. It is important to determine differences between ethnic groups, as this will assist in identifying those at higher risk of developing coronary heart disease.
Diagnostic and Interventional Radiology, 2009
Pulmoner damar sistemi veya bronfliyal damar sistemine ait Arteriovenöz Malformasyonlar(AVM) hemo... more Pulmoner damar sistemi veya bronfliyal damar sistemine ait Arteriovenöz Malformasyonlar(AVM) hemoptizinin nadir fakat hat›rlanmas› gereken nedenlerinden birisidir. Afla¤›da Gö¤üs Hastal›klar› Klini¤i taraf›ndan bronfliyal a¤aca ait bir kanama saptanmamas› üzerine ileri tetkik amac›yla servisimize yat›r›lan bir hemoptizi vakas› sunulmufltur. Bu vaka vas›tas›yla hemoptizi ay›r›c› tan›s›n› tekrar gözden geçirmek ve nedeni aç›klanamayan hemoptizi vakalar›nda AVM'nin hat›rlanmas› gerekti¤ini vurgulamak istedik.
Diagnostic and Interventional Radiology, 2009
Journal of International Medical Research, 2013
Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethn... more Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethnic groups in Istanbul, Turkey. Methods: Study participants were aged !20 years. Risk factor components for metabolic syndrome were measured and its presence was determined in study participants. Results: The study included 254 Greeks, 273 West Thracians, 275 East Turkistanis and 304 Armenians. The prevalence of metabolic syndrome was significantly different between groups (Greeks, 19.3%; West Thracians, 24.9%; East Turkistanis, 15.3%; Armenians, 20.4%), and increased with age in all groups. Low levels of high-density lipoprotein cholesterol (HDL-C) were found mainly in Greeks (females, 64.5%; males, 61.6%) and West Thracians (females, 75.8%; males, 73.1%). Among East Turkistanis, HDL-C and triglyceride levels were significantly higher compared with the other ethnic groups. Hypertension was the most frequently encountered component of metabolic syndrome in East Turkistanis. Conclusions: The prevalence of metabolic syndrome varied between ethnic groups living in the same geographical location. In Turkey, metabolic syndrome is common. It is important to determine differences between ethnic groups, as this will assist in identifying those at higher risk of developing coronary heart disease.
firattipdergisi.com
Amaç: Alkolik karaciğer sirozunda (AKS) makrositoz sıklığı ve makrositoz ile prognoz arasındaki i... more Amaç: Alkolik karaciğer sirozunda (AKS) makrositoz sıklığı ve makrositoz ile prognoz arasındaki ilişkinin belirlenerek doğruluk, duyarlılık ve özgüllük değerlerinin tespiti amaçlanmıştır. Gereç ve Yöntem: AKS tanısı olan toplam 46 hasta (grup 1) ile Hepatit B ve ...
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2005
BACKGROUND Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic man... more BACKGROUND Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic manifestations. The aim of this study was to determine the prevalence of dermatologic manifestations related to chronic HCV infection in Turkey. MATERIALS AND METHODS 70 patients with chronic HCV infection and 70 healthy volunteers were investigated. They were carefully questioned and skin, mucosa, hair and nails were systematically examined. Laboratory tests for the serum levels of aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transpeptidase, bilirubine and rheumatoid factor were done in all of them. RESULTS The only symptom which was more frequent in patients with chronic HCV infection was generalized pruritus (13 cases, 18.57%). It was observed in three cases of the control group (4.28%), the difference being statistically significant (p:0.01). In the group of patients with chronic HCV infection, three patients were diagnosed as leukocytoclastic vasculitis and thre...
European journal of internal medicine, Nov 1, 2018
Non-thyroidal illness syndrome is characterized by decreased serum free T3 (FT3) level and associ... more Non-thyroidal illness syndrome is characterized by decreased serum free T3 (FT3) level and associates with long term mortality. Serum free T4 (FT4) may affect on mortality with FT3 in course of chronic illness. This study performed to evaluate the association between both decreased FT3 with elevated FT4 levels and mortality risk. This study is a retrospective cohort analysis and consisted up 1164 (571 male, 593 female) patients with a 36 months follow up period. Patients divided into four groups according to thyroid functions. Patients with euthyroidism were in Group A, elevated FT3 in group B, decreased FT3 in group C and both decreased FT3 and elevated FT4 levels in group D. The levels of thyroid hormones and all cause mortality were compared between four groups. Mortality rate was elevated between Groups A and B, A and C, A and D, B and C, B and D, C and D, (p < .001, p < .001, p < .001, p < .001, p < .001, p:0.019, respectively). A multivariate Cox proportional ha...
Background/aims: Pegylated alfa interferon is the only immunomodulatory drug licensed for hepatit... more Background/aims: Pegylated alfa interferon is the only immunomodulatory drug licensed for hepatitis B. We evaluated the safety and tolerability of peginterferon alfa-2a (40KD) in patients with chronic hepatitis B. Materials and Methods: A total of 113 chronic hepatitis B patients under peginterferon alfa-2a (40KD; 180 μg/week) treatment were included in this multicenter, open label, non-interventional study, and 66 patients completed the follow-up period. Vital signs, physical examination and laboratory findings, concomitant medications, and adverse events were recorded. A Quality of Life questionnaire (Short Form-36) was performed twice, at the beginning and at the end of the study. Results: There was no significant difference between initial and last visits in terms of physical examination findings and Short Form-36 scores. A total of 27 adverse events were reported in 15 patients (22.7%), with most of them being mild in intensity (70.4%). The rates of the adverse events were similar in the monotherapy and combination therapy groups (peginterferon alfa-2a + lamivudine, peginterferon alfa-2a + adefovir or peginterferon alfa-2a + entecavir therapy groups), at 23.7% and 14.3%, respectively. The dosage of peginterferon had to be reduced in 3 patients (4.5%) due to thrombocytopenia. Overall patient compliance to treatment was detected as 85.9%. Conclusions: Based on the lack of serious adverse events and absence of impairment in Quality of Life, peginterferon alfa-2a (40KD, 180 μg/week, subcutaneously) treatment for 48 weeks led to a high level of patient compliance and was associated with a high degree of safety and tolerability for the treatment of adult patients with chronic hepatitis B in real-life practice.
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2005
Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic manifestations... more Chronic hepatitis C virus (HCV) infection may be associated with many dermatologic manifestations. The aim of this study was to determine the prevalence of dermatologic manifestations related to chronic HCV infection in Turkey. 70 patients with chronic HCV infection and 70 healthy volunteers were investigated. They were carefully questioned and skin, mucosa, hair and nails were systematically examined. Laboratory tests for the serum levels of aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transpeptidase, bilirubine and rheumatoid factor were done in all of them. The only symptom which was more frequent in patients with chronic HCV infection was generalized pruritus (13 cases, 18.57%). It was observed in three cases of the control group (4.28%), the difference being statistically significant (p:0.01). In the group of patients with chronic HCV infection, three patients were diagnosed as leukocytoclastic vasculitis and three as lichen planus (4.28%). Neither leuko...
Journal of International Medical Research, 2013
Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethn... more Objective: To determine the prevalence of metabolic syndrome and its risk factors in various ethnic groups in Istanbul, Turkey. Methods: Study participants were aged !20 years. Risk factor components for metabolic syndrome were measured and its presence was determined in study participants. Results: The study included 254 Greeks, 273 West Thracians, 275 East Turkistanis and 304 Armenians. The prevalence of metabolic syndrome was significantly different between groups (Greeks, 19.3%; West Thracians, 24.9%; East Turkistanis, 15.3%; Armenians, 20.4%), and increased with age in all groups. Low levels of high-density lipoprotein cholesterol (HDL-C) were found mainly in Greeks (females, 64.5%; males, 61.6%) and West Thracians (females, 75.8%; males, 73.1%). Among East Turkistanis, HDL-C and triglyceride levels were significantly higher compared with the other ethnic groups. Hypertension was the most frequently encountered component of metabolic syndrome in East Turkistanis. Conclusions: The prevalence of metabolic syndrome varied between ethnic groups living in the same geographical location. In Turkey, metabolic syndrome is common. It is important to determine differences between ethnic groups, as this will assist in identifying those at higher risk of developing coronary heart disease.
Diagnostic and Interventional Radiology, 2009