kimberly taylor - Academia.edu (original) (raw)
Papers by kimberly taylor
Journal of Legal, Ethical and Regulatory Issues, 2016
INTRODUCTIONThe recreational marijuana industry exists in an environment of legislative uncertain... more INTRODUCTIONThe recreational marijuana industry exists in an environment of legislative uncertainty resulting from states legalizing recreational marijuana while it is still considered illegal at the federal level. For the recreational marijuana industry, legalization did not occur until 2012 when Colorado first legalized it and has since been followed by three other states and Washington D.C. The dichotomy between state and federal laws has created interesting accounting and financial effects; including how financial institutions, CPAs, and the individual marijuana businesses themselves are affected by the inconsistencies in the laws from an accounting and finance perspective.From a financial institution standpoint, one of the most important aspects that is influenced by the differing state and federal laws includes providing services to marijuana-related businesses while still adhering to federal banking regulations. Banks are subject to a number of federal regulations that they m...
Journal of Computing Sciences in Colleges, 2007
It is well documented that the number of undergraduate students majoring in computer science at U... more It is well documented that the number of undergraduate students majoring in computer science at United States colleges and universities has declined in recent years [3, 7]. This situation is of gre...
Pediatric Transplantation
Immunosuppressive prophylaxis is usually given to decrease the development of acute graft versus ... more Immunosuppressive prophylaxis is usually given to decrease the development of acute graft versus host disease (GvHD) after allogeneic hematopoietic stem cell transplantation (HSCT). Belatacept is a Cytotoxic T‐lymphocyte‐associated protein 4, blocking agent, an immunosuppressive agent used for organ rejection prevention in adult renal transplant recipients.
Texas A&M Journal of Property Law
At the time of this Article, at least twelve large wildfires are burn- ing in California across m... more At the time of this Article, at least twelve large wildfires are burn- ing in California across more than 1,000 square miles, having damaged or destroyed over 2,000 structures, according to the California Department of Forestry and Fire Protection (CAL FIRE). At least eight people have lost their lives. The Kilauea volcano continues to erupt in Hawaii, having destroyed 600 homes. The 2018 hurricane season is in full swing, and while there have been no catastrophic events to date, residents in Houston, Florida, Puerto Rico, and elsewhere are still recovering from the devastating winds and rains wrought by Har- vey, Maria, and Irma last year. Those hurricanes are estimated to have caused more than $200 billion in damages, making the 2017 hurricane season the costliest in U.S. history. Around the world, natural disasters such as deadly heat waves, flooding, mudslides, hurricanes, and tornadoes will cause untold losses as temperatures across the globe are rising. After the smoke clears,...
Health Marketing Quarterly
Abstract Breast cancer related promotions, advertising, and pink ribbons are now ubiquitous in Oc... more Abstract Breast cancer related promotions, advertising, and pink ribbons are now ubiquitous in October, yet comparatively little is known about how this advertising impacts breast cancer survivors specifically. The present research uses an embodied knowledge perspective to explore the impact of cancer advertising on female breast cancer survivors. Five focus groups were conducted with 42 participants, and the discussions were analyzed to find common themes. The survivors expressed a desire for cancer advertising to be representative, informative (particularly regarding detection and treatment options), hopeful, and transparent about the organization’s motivation and support. Implications and recommendations are also discussed.
Biology of Blood and Marrow Transplantation
Stroke, Mar 30, 2018
Human amnion epithelial cells (hAECs) are nonimmunogenic, nontumorigenic, anti-inflammatory cells... more Human amnion epithelial cells (hAECs) are nonimmunogenic, nontumorigenic, anti-inflammatory cells normally discarded with placental tissue. We reasoned that their profile of biological features, wide availability, and the lack of ethical barriers to their use could make these cells useful as a therapy in ischemic stroke. We tested the efficacy of acute (1.5 hours) or delayed (1-3 days) poststroke intravenous injection of hAECs in 4 established animal models of cerebral ischemia. Animals included young (7-14 weeks) and aged mice (20-22 months) of both sexes, as well as adult marmosets of either sex. We found that hAECs administered 1.5 hours after stroke in mice migrated to the ischemic brain via a CXC chemokine receptor type 4-dependent mechanism and reduced brain inflammation, infarct development, and functional deficits. Furthermore, if hAECs administration was delayed until 1 or 3 days poststroke, long-term functional recovery was still augmented in young and aged mice of both se...
Annals of Pharmacotherapy
Background: Tacrolimus, commonly used for graft versus host disease prophylaxis is usually admini... more Background: Tacrolimus, commonly used for graft versus host disease prophylaxis is usually administered via a dedicated central venous line (CVL) and trough levels drawn from the unexposed lumen. Being an oil-based medication, it may be adsorbed to the inner lumen of the CVL and result in falsely high levels drawn from an inadvertently exposed lumen. There is no treatment for decontamination of such CVLs, and natural decay occurs over months before the CVL can be used to draw reliable trough levels. Objective: The primary objective of the study was to estimate the effectiveness of 70% ethanol locks for decontaminating CVLs exposed to tacrolimus. Methods: We studied the efficacy of 70% ethanol lock in decontaminating CVLs exposed to tacrolimus in patients during transplant. Trough tacrolimus levels were drawn from the exposed and unexposed (control) lumens at 8:00 am, followed by a 2-mL 70% ethanol lock instilled for a 2-hour dwell into the exposed (intervention) lumen. Trough tacrol...
Scientific reports, Mar 13, 2017
Interactions of high-frequency radio waves (RF) with biological tissues are currently being inves... more Interactions of high-frequency radio waves (RF) with biological tissues are currently being investigated as a therapeutic platform for non-invasive cancer hyperthermia therapy. RF delivers thermal energy into tissues, which increases intra-tumoral drug perfusion and blood-flow. Herein, we describe an optical-based method to optimize the short-term treatment schedules of drug and hyperthermia administration in a 4T1 breast cancer model via RF, with the aim of maximizing drug localization and homogenous distribution within the tumor microenvironment. This method, based on the analysis of fluorescent dyes localized into the tumor, is more time, cost and resource efficient, when compared to current analytical methods for tumor-targeting drug analysis such as HPLC and LC-MS. Alexa-Albumin 647 nm fluorphore was chosen as a surrogate for nab-paclitaxel based on its similar molecular weight and albumin driven pharmacokinetics. We found that RF hyperthermia induced a 30-40% increase in Alexa...
Arthritis & rheumatology (Hoboken, N.J.), Jun 11, 2017
Sjögren's Syndrome (SS) is a systemic autoimmune disease affecting primarily the lacrimal and... more Sjögren's Syndrome (SS) is a systemic autoimmune disease affecting primarily the lacrimal and salivary glands. The Sjögren's International Collaborative Clinical Alliance (SICCA) is an international multisite observational study whose participants have been genotyped on the Omni 2.5M platform and undergone deep phenotyping using common protocol-directed methods, providing a unique opportunity to examine the genetic etiology of SS across ancestry and disease subsets. We perform GWAS analyses utilizing dbGaP controls on all subjects (1405 cases, 1622 SICCA controls, 3125 external controls), European (similarly 585, 966, 2580), and Asian (similarly 460, 224, 901) with ancestry adjustments via principal component analyses. We also investigate whether subphenotype distributions differ by ethnicity and if this contributes to heterogeneity of genetic associations. We see significant associations in established regions of the MHC, IRF5, and STAT4 (p=3e-42, p=3e-14, p=9e-10, respecti...
Human vaccines & immunotherapeutics, Apr 23, 2016
We conducted a randomized, double-blind, placebo-controlled dose-escalation study in healthy adul... more We conducted a randomized, double-blind, placebo-controlled dose-escalation study in healthy adults to evaluate the safety and immunogenicity of recombinant Staphylococcus aureus candidate vaccine antigens, recombinant α-toxoid (rAT) and a sub-unit of Panton-Valentine leukocidin (rLukS-PV). 176 subjects were enrolled and randomized within 1 of 11 treatment cohorts: monovalent rAT or rLukS-PV dosages of 10, 25, 50, and 100 μg; bivalent rAT:rLukS dosages of 10:10, 25:25, and 50:50 μg; and alum or saline placebo. All subjects were assessed at Days 0, 7, 14, 28, and 84. Subjects in the 50:50 μg bivalent cohort received a second injection on Day 84 and were assessed on Days 98 and 112. Incidence and severity of reactogenicity and adverse events (AEs) were compared. Geometric mean serum concentrations (GMC) and neutralizing activity of anti-rAT and anti-rLukS-PV IgG were assessed. Reactogenicity incidence was significantly higher in vaccine than placebo recipients (77% versus 55%, respect...
Surgical laparoscopy, endoscopy & percutaneous techniques, Jan 19, 2016
Minimally invasive approaches to adrenal surgery were adopted in an attempt to reduce surgical mo... more Minimally invasive approaches to adrenal surgery were adopted in an attempt to reduce surgical morbidity. Despite the widespread use, few studies objectively evaluate health-related quality of life (HRQOL) in patients undergoing laparoscopic adrenalectomy (LA). We assessed patients' health status and recovery after LA with the use of validated questionnaires. Patients seen in urology clinic for evaluation of adrenal surgery were enlisted in our prospective, patient-reported, HRQOL study assessing postoperative recovery. HRQOL was measured using Convalescence And Recovery Evaluation (CARE) and Short Form-12 questionnaires administered before surgery and at 2, 4, 8, 12 weeks and annually after surgery. All operations were performed using a laparoscopic transperitoneal approach by a single fellowship-trained surgeon. A total of 30 patients who met study inclusion criteria from July 2009 to November 2014 were included in our evaluation. Mean patient age was 53 years. Tumor size rang...
Star Tribune, Jun 30, 1999
Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society Engineering in Medicine and Biology, Nov 23, 2002
An engineered approach which uses the collective wisdom of the Clinical Engineering profession ha... more An engineered approach which uses the collective wisdom of the Clinical Engineering profession has been applied at the grass-roots level successfully in the Northwest Territories of Canada. The success of this approach has allowed this technology management model to be expanded to provide leadership and support at the policy/bureaucratic level of the Department of Health and Social Services.
Star Tribune, Oct 22, 1997
Journal of Advertising Research, 2003
... KIMBERLY A. TAYLOR Florida International University kimberly.taylor@fiu.edu ... Agencies may ... more ... KIMBERLY A. TAYLOR Florida International University kimberly.taylor@fiu.edu ... Agencies may take their role for granted and become complacent, thus mak-ing themselves less valuable as a strategic partner (Grayson and Ambler, 1999). ...
Journal of Pediatric Oncology Nursing, 2000
care settings. The assumption underlying this priority is that a direct relationship exists betwe... more care settings. The assumption underlying this priority is that a direct relationship exists between positive nursing care outcomes for patients and a supportive work environment for nurses. In a series of five studies, we have tested all or select components of the StressResponse Sequence model (SRS) to determine the strength of the relationships between role-related stress, coping, and work consequences. The combined study findings indicated that the SRS model needed to be
Journal of Legal, Ethical and Regulatory Issues, 2016
INTRODUCTIONThe recreational marijuana industry exists in an environment of legislative uncertain... more INTRODUCTIONThe recreational marijuana industry exists in an environment of legislative uncertainty resulting from states legalizing recreational marijuana while it is still considered illegal at the federal level. For the recreational marijuana industry, legalization did not occur until 2012 when Colorado first legalized it and has since been followed by three other states and Washington D.C. The dichotomy between state and federal laws has created interesting accounting and financial effects; including how financial institutions, CPAs, and the individual marijuana businesses themselves are affected by the inconsistencies in the laws from an accounting and finance perspective.From a financial institution standpoint, one of the most important aspects that is influenced by the differing state and federal laws includes providing services to marijuana-related businesses while still adhering to federal banking regulations. Banks are subject to a number of federal regulations that they m...
Journal of Computing Sciences in Colleges, 2007
It is well documented that the number of undergraduate students majoring in computer science at U... more It is well documented that the number of undergraduate students majoring in computer science at United States colleges and universities has declined in recent years [3, 7]. This situation is of gre...
Pediatric Transplantation
Immunosuppressive prophylaxis is usually given to decrease the development of acute graft versus ... more Immunosuppressive prophylaxis is usually given to decrease the development of acute graft versus host disease (GvHD) after allogeneic hematopoietic stem cell transplantation (HSCT). Belatacept is a Cytotoxic T‐lymphocyte‐associated protein 4, blocking agent, an immunosuppressive agent used for organ rejection prevention in adult renal transplant recipients.
Texas A&M Journal of Property Law
At the time of this Article, at least twelve large wildfires are burn- ing in California across m... more At the time of this Article, at least twelve large wildfires are burn- ing in California across more than 1,000 square miles, having damaged or destroyed over 2,000 structures, according to the California Department of Forestry and Fire Protection (CAL FIRE). At least eight people have lost their lives. The Kilauea volcano continues to erupt in Hawaii, having destroyed 600 homes. The 2018 hurricane season is in full swing, and while there have been no catastrophic events to date, residents in Houston, Florida, Puerto Rico, and elsewhere are still recovering from the devastating winds and rains wrought by Har- vey, Maria, and Irma last year. Those hurricanes are estimated to have caused more than $200 billion in damages, making the 2017 hurricane season the costliest in U.S. history. Around the world, natural disasters such as deadly heat waves, flooding, mudslides, hurricanes, and tornadoes will cause untold losses as temperatures across the globe are rising. After the smoke clears,...
Health Marketing Quarterly
Abstract Breast cancer related promotions, advertising, and pink ribbons are now ubiquitous in Oc... more Abstract Breast cancer related promotions, advertising, and pink ribbons are now ubiquitous in October, yet comparatively little is known about how this advertising impacts breast cancer survivors specifically. The present research uses an embodied knowledge perspective to explore the impact of cancer advertising on female breast cancer survivors. Five focus groups were conducted with 42 participants, and the discussions were analyzed to find common themes. The survivors expressed a desire for cancer advertising to be representative, informative (particularly regarding detection and treatment options), hopeful, and transparent about the organization’s motivation and support. Implications and recommendations are also discussed.
Biology of Blood and Marrow Transplantation
Stroke, Mar 30, 2018
Human amnion epithelial cells (hAECs) are nonimmunogenic, nontumorigenic, anti-inflammatory cells... more Human amnion epithelial cells (hAECs) are nonimmunogenic, nontumorigenic, anti-inflammatory cells normally discarded with placental tissue. We reasoned that their profile of biological features, wide availability, and the lack of ethical barriers to their use could make these cells useful as a therapy in ischemic stroke. We tested the efficacy of acute (1.5 hours) or delayed (1-3 days) poststroke intravenous injection of hAECs in 4 established animal models of cerebral ischemia. Animals included young (7-14 weeks) and aged mice (20-22 months) of both sexes, as well as adult marmosets of either sex. We found that hAECs administered 1.5 hours after stroke in mice migrated to the ischemic brain via a CXC chemokine receptor type 4-dependent mechanism and reduced brain inflammation, infarct development, and functional deficits. Furthermore, if hAECs administration was delayed until 1 or 3 days poststroke, long-term functional recovery was still augmented in young and aged mice of both se...
Annals of Pharmacotherapy
Background: Tacrolimus, commonly used for graft versus host disease prophylaxis is usually admini... more Background: Tacrolimus, commonly used for graft versus host disease prophylaxis is usually administered via a dedicated central venous line (CVL) and trough levels drawn from the unexposed lumen. Being an oil-based medication, it may be adsorbed to the inner lumen of the CVL and result in falsely high levels drawn from an inadvertently exposed lumen. There is no treatment for decontamination of such CVLs, and natural decay occurs over months before the CVL can be used to draw reliable trough levels. Objective: The primary objective of the study was to estimate the effectiveness of 70% ethanol locks for decontaminating CVLs exposed to tacrolimus. Methods: We studied the efficacy of 70% ethanol lock in decontaminating CVLs exposed to tacrolimus in patients during transplant. Trough tacrolimus levels were drawn from the exposed and unexposed (control) lumens at 8:00 am, followed by a 2-mL 70% ethanol lock instilled for a 2-hour dwell into the exposed (intervention) lumen. Trough tacrol...
Scientific reports, Mar 13, 2017
Interactions of high-frequency radio waves (RF) with biological tissues are currently being inves... more Interactions of high-frequency radio waves (RF) with biological tissues are currently being investigated as a therapeutic platform for non-invasive cancer hyperthermia therapy. RF delivers thermal energy into tissues, which increases intra-tumoral drug perfusion and blood-flow. Herein, we describe an optical-based method to optimize the short-term treatment schedules of drug and hyperthermia administration in a 4T1 breast cancer model via RF, with the aim of maximizing drug localization and homogenous distribution within the tumor microenvironment. This method, based on the analysis of fluorescent dyes localized into the tumor, is more time, cost and resource efficient, when compared to current analytical methods for tumor-targeting drug analysis such as HPLC and LC-MS. Alexa-Albumin 647 nm fluorphore was chosen as a surrogate for nab-paclitaxel based on its similar molecular weight and albumin driven pharmacokinetics. We found that RF hyperthermia induced a 30-40% increase in Alexa...
Arthritis & rheumatology (Hoboken, N.J.), Jun 11, 2017
Sjögren's Syndrome (SS) is a systemic autoimmune disease affecting primarily the lacrimal and... more Sjögren's Syndrome (SS) is a systemic autoimmune disease affecting primarily the lacrimal and salivary glands. The Sjögren's International Collaborative Clinical Alliance (SICCA) is an international multisite observational study whose participants have been genotyped on the Omni 2.5M platform and undergone deep phenotyping using common protocol-directed methods, providing a unique opportunity to examine the genetic etiology of SS across ancestry and disease subsets. We perform GWAS analyses utilizing dbGaP controls on all subjects (1405 cases, 1622 SICCA controls, 3125 external controls), European (similarly 585, 966, 2580), and Asian (similarly 460, 224, 901) with ancestry adjustments via principal component analyses. We also investigate whether subphenotype distributions differ by ethnicity and if this contributes to heterogeneity of genetic associations. We see significant associations in established regions of the MHC, IRF5, and STAT4 (p=3e-42, p=3e-14, p=9e-10, respecti...
Human vaccines & immunotherapeutics, Apr 23, 2016
We conducted a randomized, double-blind, placebo-controlled dose-escalation study in healthy adul... more We conducted a randomized, double-blind, placebo-controlled dose-escalation study in healthy adults to evaluate the safety and immunogenicity of recombinant Staphylococcus aureus candidate vaccine antigens, recombinant α-toxoid (rAT) and a sub-unit of Panton-Valentine leukocidin (rLukS-PV). 176 subjects were enrolled and randomized within 1 of 11 treatment cohorts: monovalent rAT or rLukS-PV dosages of 10, 25, 50, and 100 μg; bivalent rAT:rLukS dosages of 10:10, 25:25, and 50:50 μg; and alum or saline placebo. All subjects were assessed at Days 0, 7, 14, 28, and 84. Subjects in the 50:50 μg bivalent cohort received a second injection on Day 84 and were assessed on Days 98 and 112. Incidence and severity of reactogenicity and adverse events (AEs) were compared. Geometric mean serum concentrations (GMC) and neutralizing activity of anti-rAT and anti-rLukS-PV IgG were assessed. Reactogenicity incidence was significantly higher in vaccine than placebo recipients (77% versus 55%, respect...
Surgical laparoscopy, endoscopy & percutaneous techniques, Jan 19, 2016
Minimally invasive approaches to adrenal surgery were adopted in an attempt to reduce surgical mo... more Minimally invasive approaches to adrenal surgery were adopted in an attempt to reduce surgical morbidity. Despite the widespread use, few studies objectively evaluate health-related quality of life (HRQOL) in patients undergoing laparoscopic adrenalectomy (LA). We assessed patients' health status and recovery after LA with the use of validated questionnaires. Patients seen in urology clinic for evaluation of adrenal surgery were enlisted in our prospective, patient-reported, HRQOL study assessing postoperative recovery. HRQOL was measured using Convalescence And Recovery Evaluation (CARE) and Short Form-12 questionnaires administered before surgery and at 2, 4, 8, 12 weeks and annually after surgery. All operations were performed using a laparoscopic transperitoneal approach by a single fellowship-trained surgeon. A total of 30 patients who met study inclusion criteria from July 2009 to November 2014 were included in our evaluation. Mean patient age was 53 years. Tumor size rang...
Star Tribune, Jun 30, 1999
Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society Engineering in Medicine and Biology, Nov 23, 2002
An engineered approach which uses the collective wisdom of the Clinical Engineering profession ha... more An engineered approach which uses the collective wisdom of the Clinical Engineering profession has been applied at the grass-roots level successfully in the Northwest Territories of Canada. The success of this approach has allowed this technology management model to be expanded to provide leadership and support at the policy/bureaucratic level of the Department of Health and Social Services.
Star Tribune, Oct 22, 1997
Journal of Advertising Research, 2003
... KIMBERLY A. TAYLOR Florida International University kimberly.taylor@fiu.edu ... Agencies may ... more ... KIMBERLY A. TAYLOR Florida International University kimberly.taylor@fiu.edu ... Agencies may take their role for granted and become complacent, thus mak-ing themselves less valuable as a strategic partner (Grayson and Ambler, 1999). ...
Journal of Pediatric Oncology Nursing, 2000
care settings. The assumption underlying this priority is that a direct relationship exists betwe... more care settings. The assumption underlying this priority is that a direct relationship exists between positive nursing care outcomes for patients and a supportive work environment for nurses. In a series of five studies, we have tested all or select components of the StressResponse Sequence model (SRS) to determine the strength of the relationships between role-related stress, coping, and work consequences. The combined study findings indicated that the SRS model needed to be