kim kim - Academia.edu (original) (raw)

Papers by kim kim

Journal of Instrumentation, 2008

Nuclear Physics A, 2009

* Large backgrounds, quality uncertain as yet.

Nuclear Fusion, 2001

The extensive design effort for KSTAR has been focused on two major aspects of the KSTAR project ... more The extensive design effort for KSTAR has been focused on two major aspects of the KSTAR project mission -steady-state-operation capability and advanced tokamak physics. The steady state aspect of the mission is reflected in the choice of superconducting magnets, provision of actively cooled in-vessel components, and long pulse current drive and heating systems. The advanced tokamak aspect of the mission is incorporated in the design features associated with flexible plasma shaping, double null divertor and passive stabilizers, internal control coils and a comprehensive set of diagnostics. Substantial progress in engineering has been made on superconducting magnets, the vacuum vessel, plasma facing components and power supplies. The new KSTAR experimental facility with cryogenic system and deionized water cooling and main power systems has been designed, and the construction work is under way for completion in 2004.

A detailed study is presented of the expected performance of the ATLAS detector. The reconstructi... more A detailed study is presented of the expected performance of the ATLAS detector. The reconstruction of tracks, leptons, photons, missing energy and jets is investigated, together with the performance of b-tagging and the trigger. The physics potential for a variety of interesting physics processes, within the Standard Model and beyond, is examined. The study comprises a series of notes based on simulations of the detector and physics processes, with particular emphasis given to the data expected from the first years of operation of the LHC at CERN.

Nature, 2007

AMP-activated protein kinase (AMPK, also known as SNF1A) has been primarily studied as a metaboli... more AMP-activated protein kinase (AMPK, also known as SNF1A) has been primarily studied as a metabolic regulator that is activated in response to energy deprivation 1 . Although there is relatively ample information on the biochemical characteristics of AMPK, not enough data exist on the in vivo function of the kinase. Here, using the Drosophila model system, we generated the first animal model with no AMPK activity and discovered physiological functions of the kinase. Surprisingly, AMPK-null mutants were lethal with severe abnormalities in cell polarity and mitosis, similar to those of lkb1-null mutants. Constitutive activation of AMPK restored many of the phenotypes of lkb1-null mutants, suggesting that AMPK mediates the polarity-and mitosis-controlling functions of the LKB1 serine/threonine kinase. Interestingly, the regulatory site of non-muscle myosin regulatory light chain (MRLC; also known as MLC2) 2,3 was directly phosphorylated by AMPK. Moreover, the phosphomimetic mutant of MRLC 3 rescued the AMPKnull defects in cell polarity and mitosis, suggesting MRLC is a critical downstream target of AMPK. Furthermore, the activation of AMPK by energy deprivation was sufficient to cause dramatic changes in cell shape, inducing complete polarization and brush border formation in the human LS174T cell line, through the phosphorylation of MRLC. Taken together, our results demonstrate that AMPK has highly conserved roles across metazoan species not only in the control of metabolism, but also in the regulation of cellular structures.

IEEE Transactions on Microwave Theory and Techniques, 2008

A saturated Doherty amplifier based on class-F amplifiers is analyzed in terms of its load modula... more A saturated Doherty amplifier based on class-F amplifiers is analyzed in terms of its load modulation behavior, efficiency, and linearity. Simulations included the amplitude ratio and phase difference between the fundamental and third harmonic voltages, the current/voltage waveforms, load lines, and the third-order intermodulation amplitudes/phases of the carrier and peaking amplifiers. The saturated Doherty power amplifier was implemented using two Eudyna EGN010MK GaN HEMTs with a 10-W peak envelope power. For a 2.14-GHz forward-link wideband code-division multiple-access signal, the Doherty amplifier delivers an excellent efficiency of 52.4% with an acceptable linearity of 28.3 dBc at an average output power of 36 dBm. Moreover, the amplifier can provide the high linearity performance of 50 dBc using the digital feedback predistortion technique.

Concurrent Engineering: Research and Applications, 1998

... proposes an approach to these requirements that uses an Internet based client/server ... Firs... more ... proposes an approach to these requirements that uses an Internet based client/server ... First the overall ar-chitecture of the CyberView distributed Concurrent Engi-neering ... Two essential elements of CyberView are concerned with storage, visualization, and communication of 3D ...

The paper discusses a multi-agent system for robot-soccer. The system consists of a supervisory c... more The paper discusses a multi-agent system for robot-soccer. The system consists of a supervisory controller, and controllers for attack, defense and goalie robots. Real time vector field based path planning, Petri-net theory and Q-learning technique are used in the design. Robot-soccer system has a dynamic environment. A soccer robot has to take an appropriate decision based on environment situation. The supervisor assigns the role of each robot. Experimental study verifies applicability and efficiency of the developed controller scheme.

Physical Review Letters, 2003

The K2K experiment observes indications of neutrino oscillation: a reduction of numu\nu_\munumu flux to... more The K2K experiment observes indications of neutrino oscillation: a reduction of numu\nu_\munumu flux together with a distortion of the energy spectrum. Fifty-six beam neutrino events are observed in Super-Kamiokande (SK), 250 km from the neutrino production point, with an expectation of 80.1+6.2−5.480.1^{+6.2}_{-5.4}80.1+6.2−5.4. Twenty-nine one ring mu\mumu-like events are used to reconstruct the neutrino energy spectrum, which is better matched to the expected spectrum with neutrino oscillation than without. The probability that the observed flux at SK is explained by statistical fluctuation without neutrino oscillation is less than 1%.

Etri Journal, 1996

This paper derives the symbol error probability for quadrature amplitude modulation(QAM) with L-f... more This paper derives the symbol error probability for quadrature amplitude modulation(QAM) with L-fold space diversity in Rayleigh fading channels. Two combining techniques, maximal ratio combin-ing(MRC) and selection combining(SC), are con-sidered. The formula for MRC ...

Genome Research, 2009

We present the first Korean individual genome sequence (SJK) and analysis results. The diploid ge... more We present the first Korean individual genome sequence (SJK) and analysis results. The diploid genome of a Korean male was sequenced to 28.95-fold redundancy using the Illumina paired-end sequencing method. SJK covered 99.9% of the NCBI human reference genome. We identified 420,083 novel single nucleotide polymorphisms (SNPs) that are not in the dbSNP database. Despite a close similarity, significant differences were observed between the Chinese genome (YH), the only other Asian genome available, and SJK: (1) 39.87% (1,371,239 out of 3,439,107) SNPs were SJK-specific (49.51% against Venter's, 46.94% against Watson's, and 44.17% against the Yoruba genomes); (2) 99.5% (22,495 out of 22,605) of short indels (< 4 bp) discovered on the same loci had the same size and type as YH; and (3) 11.3% (331 out of 2920) deletion structural variants were SJK-specific. Even after attempting to map unmapped reads of SJK to unanchored NCBI scaffolds, HGSV, and available personal genomes, there were still 5.77% SJK reads that could not be mapped. All these findings indicate that the overall genetic differences among individuals from closely related ethnic groups may be significant. Hence, constructing reference genomes for minor socio-ethnic groups will be useful for massive individual genome sequencing.

Autoimmune chronic pancreatitis (AIP) is increasingly being recognized worldwidely, as knowledge ... more Autoimmune chronic pancreatitis (AIP) is increasingly being recognized worldwidely, as knowledge of this entity builds up. Above all, AIP is a very attractive disease to clinicians in terms of its dramatic response to the oral steroid therapy in contrast to ordinary chronic pancreatitis. Although many characteristic fi ndings of AIP have been described, definite diagnostic criteria have not been fully established. In the year 2002, the Japan Pancreas Society published the diagnostic criteria of AIP and many clinicians around the world use these criteria for the diagnosis of AIP. The diagnostic criteria proposed by the Japan Pancreas Society, however, are not completely satisfactory and some groups use their own criteria in reporting AIP. This review discusses several potential limitations of current diagnostic criteria for this increasingly recognized condition. The manuscript is organized to emphasize the need for convening a consensus to develop improved diagnostic criteria.