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Research paper thumbnail of PERANCANGAN SISTEM INFORMASI PENGELOLAHAN RETRIBUSI PASAR BERBASIS WEB PADA DINAS KOPERASI PERINDUSTRIAN DAN PERDAGANGAN BONDOWOSO

Research paper thumbnail of PERANCANGAN SISTEM INFORMASI PENGELOLAHAN RETRIBUSI PASAR BERBASIS WEB PADA DINAS KOPERASI PERINDUSTRIAN DAN PERDAGANGAN BONDOWOSO

Academi.edu, 2024

Retribusi Pasar merupakan salah satu sumber Pendapatan Asli Daerah (PAD), yang harus dikelolah de... more Retribusi Pasar merupakan salah satu sumber Pendapatan Asli Daerah (PAD), yang harus dikelolah dengan baik sehingga memberikan kontribusi yang maksimal kepada daerah. baik itu pasar yang dimiliki oleh pemerintah daerah, pasar tradisional maupun pasar semi modern harus dikelolah degan tata kelolah yang baik (good governance and good arrangement) sehingga pengelolahan pasar menjadi lebih efektif. Pengelolah pasar merupakan kegiatan yang cukup kompleks, banyak hal yang harus dikelolah salah satunya adalah pengelolahan retribusi pasar. Retribusi pasar merupakan pungutan biyaya atas penggunaan fasilitas pasar berupa plataran, los, kios dan tokoh. yang dikelolah oleh daerah tau DISKOPRINDAG Bondowoso serta khusus di sediakan untuk pedagang. retribusi pasar termasuk kepada retribusi daerah. dengan perhatian yang lebih dan pengelolahan yang baik tidak menutup kemungkinana retribusi pasar dapat menyumbang Pendapatan Asli Daerah (PAD) yang cukup besar.

Research paper thumbnail of Laila nur yasmin

Research paper thumbnail of Spectral dynamic causal modelling of resting-state fMRI: an exploratory study relating effective brain connectivity in the default mode network to genetics

Statistical Applications in Genetics and Molecular Biology, Jun 1, 2020

We conduct an imaging genetics study to explore how effective brain connectivity in the default m... more We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of longitudinal resting-state functional magnetic resonance imaging (rs-fMRI) and genetic data obtained from a sample of 111 subjects with a total of 319 rs-fMRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. A Dynamic Causal Model (DCM) is fit to the rs-fMRI scans to estimate effective brain connectivity within the DMN and related to a set of single nucleotide polymorphisms (SNPs) contained in an empirical disease-constrained set which is obtained out-of-sample from 663 ADNI subjects having only genome-wide data. We relate longitudinal effective brain connectivity estimated using spectral DCM to SNPs using both linear mixed effect (LME) models as well as function-onscalar regression (FSR). In both cases we implement a parametric bootstrap for testing SNP coefficients and make comparisons with p-values obtained from asymptotic null distributions. In both networks at an initial q-value threshold of 0.1 no effects are found. We report on exploratory patterns of associations with relatively high ranks that exhibit stability to the differing assumptions made by both FSR and LME.

Research paper thumbnail of Spectral Dynamic Causal Modelling of Resting-State fMRI: Relating Effective Brain Connectivity in the Default Mode Network to Genetics

arXiv (Cornell University), Jan 28, 2019

We conduct an imaging genetics study to explore how effective brain connectivity in the default m... more We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of longitudinal resting-state functional magnetic resonance imaging (rs-fMRI) and genetic data obtained from a sample of 111 subjects with a total of 319 rs-fMRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. A Dynamic Causal Model (DCM) is fit to the rs-fMRI scans to estimate effective brain connectivity within the DMN and related to a set of single nucleotide polymorphisms (SNPs) contained in an empirical disease-constrained set which is obtained out-of-sample from 663 ADNI subjects having only genome-wide data. We examine longitudinal data in both a 4-region and an 6-region network and relate longitudinal effective brain connectivity networks estimated using spectral DCM to SNPs using both linear mixed effect (LME) models as well as function-on-scalar regression (FSR). In the former case we implement a parametric bootstrap for testing SNP coefficients and make comparisons with p-values obtained from the chi-squared null distribution. We also implement a parametric bootstrap approach for testing regression functions in FSR and we make comparisons between p-values obtained from the parametric bootstrap to p-values obtained using the F-distribution with degreesof-freedom based on Satterthwaite's approximation.

Research paper thumbnail of Ultrasound-Guided Drainage of Breast Abscess

Scholars journal of applied medical sciences, Dec 12, 2022

Original Research Article Objective: To assess the efficacy of ultrasound-guided drainage of brea... more Original Research Article Objective: To assess the efficacy of ultrasound-guided drainage of breast abscesses with special attention to the risk of recurrence and the need for surgical treatment, to avoid postoperative morbidity, to reduce the hospital stay and cost of treatment, to determine the need for termination of breast feeding. Methods: 100 patients with breast were selected conveniently among those who were admitted in Dinajpur Medical College hospital or visited to surgery OPD with breast abscess. They were evaluated by short history, clinical examination and ultrasonogram. After counseling and taking consent they were treated with ultrasound-guided drainage, by needle or pigtail catheter under local anaesthesia. Follow-up punctures were performed at 2 or 3 day intervals until the clinical condition and ultrasound findings had improved. All patients were treated with oral antibiotics. Mammography was performed to search for underlying cancer. Results: Among the 100 cases included in the study, ninety-seven 97% patients with puerperal abscesses and 81% with non-puerperal abscesses recovered after the first round of ultrasound-guided drainage. One patient in each group had recurrence in loco but recovered after further ultrasound-guided drainage. Seven patients, 6 with nonpuerperal and 01 with puerperal abscesses, underwent surgical excision of the abscess cavity or fistulas. Breastfeeding continued and 23 patients were treated as outpatients. The median number of follow up examinations in the ultrasounddepartment was four (range 1-10) for the group of patients with puerperal abscess and three (range 1-7) in the group of patients with non-puerperal abscess. The corresponding figure for the median number of punctures was for both groups one (range 1-6 and 1-4). There were no reports of newly diagnosed breast cancer in the 1-year follow-up period. Conclusion: Treatment of breast abscess with US-guided Percutaneous aspiration or Pigtail catheter drainage both in puerperal and non-puerperal breast abscess has a high rate of success, no need to stop breast feeding, avoids postoperative morbidity, less hospital stay as well as cost of treatment.

Research paper thumbnail of Therapeutic Options in the Treatment of Clozapine-Induced Adverse Effects

Journal of Pharmacy Technology, 2004

Objective:To review the therapeutic options in the management of clozapine-induced adverse effect... more Objective:To review the therapeutic options in the management of clozapine-induced adverse effects.Data Sources:A MEDLINE search (from 1966 to present) was conducted, and English-language studies and review articles were retrieved to review the adverse effects of clozapine and their management.Study Selection and Data Extraction:All studies evaluating clozapine's adverse effects, such as agranulocytosis, seizures, neuroleptic malignant syndrome, hypersalivation, weight gain, sedation, fatigue, orthostatic hypotension, eosinophilia, delirium, new-onset diabetes, constipation, nausea, tachycardia, myocarditis, and pancreatitis, and their management were included.Data Synthesis:Clozapine, an atypical antipsychotic that has been proven effective and comparable, as well as superior, to conventional antipsychotics in treatment-resistant schizophrenia, is also being used in the treatment of a wide variety of other psychiatric conditions, including suicidal ideation, tardive dyskinesia,...

Research paper thumbnail of PERANCANGAN SISTEM INFORMASI PENGELOLAHAN RETRIBUSI PASAR BERBASIS WEB PADA DINAS KOPERASI PERINDUSTRIAN DAN PERDAGANGAN BONDOWOSO

Research paper thumbnail of PERANCANGAN SISTEM INFORMASI PENGELOLAHAN RETRIBUSI PASAR BERBASIS WEB PADA DINAS KOPERASI PERINDUSTRIAN DAN PERDAGANGAN BONDOWOSO

Academi.edu, 2024

Retribusi Pasar merupakan salah satu sumber Pendapatan Asli Daerah (PAD), yang harus dikelolah de... more Retribusi Pasar merupakan salah satu sumber Pendapatan Asli Daerah (PAD), yang harus dikelolah dengan baik sehingga memberikan kontribusi yang maksimal kepada daerah. baik itu pasar yang dimiliki oleh pemerintah daerah, pasar tradisional maupun pasar semi modern harus dikelolah degan tata kelolah yang baik (good governance and good arrangement) sehingga pengelolahan pasar menjadi lebih efektif. Pengelolah pasar merupakan kegiatan yang cukup kompleks, banyak hal yang harus dikelolah salah satunya adalah pengelolahan retribusi pasar. Retribusi pasar merupakan pungutan biyaya atas penggunaan fasilitas pasar berupa plataran, los, kios dan tokoh. yang dikelolah oleh daerah tau DISKOPRINDAG Bondowoso serta khusus di sediakan untuk pedagang. retribusi pasar termasuk kepada retribusi daerah. dengan perhatian yang lebih dan pengelolahan yang baik tidak menutup kemungkinana retribusi pasar dapat menyumbang Pendapatan Asli Daerah (PAD) yang cukup besar.

Research paper thumbnail of Laila nur yasmin

Research paper thumbnail of Spectral dynamic causal modelling of resting-state fMRI: an exploratory study relating effective brain connectivity in the default mode network to genetics

Statistical Applications in Genetics and Molecular Biology, Jun 1, 2020

We conduct an imaging genetics study to explore how effective brain connectivity in the default m... more We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of longitudinal resting-state functional magnetic resonance imaging (rs-fMRI) and genetic data obtained from a sample of 111 subjects with a total of 319 rs-fMRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. A Dynamic Causal Model (DCM) is fit to the rs-fMRI scans to estimate effective brain connectivity within the DMN and related to a set of single nucleotide polymorphisms (SNPs) contained in an empirical disease-constrained set which is obtained out-of-sample from 663 ADNI subjects having only genome-wide data. We relate longitudinal effective brain connectivity estimated using spectral DCM to SNPs using both linear mixed effect (LME) models as well as function-onscalar regression (FSR). In both cases we implement a parametric bootstrap for testing SNP coefficients and make comparisons with p-values obtained from asymptotic null distributions. In both networks at an initial q-value threshold of 0.1 no effects are found. We report on exploratory patterns of associations with relatively high ranks that exhibit stability to the differing assumptions made by both FSR and LME.

Research paper thumbnail of Spectral Dynamic Causal Modelling of Resting-State fMRI: Relating Effective Brain Connectivity in the Default Mode Network to Genetics

arXiv (Cornell University), Jan 28, 2019

We conduct an imaging genetics study to explore how effective brain connectivity in the default m... more We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of longitudinal resting-state functional magnetic resonance imaging (rs-fMRI) and genetic data obtained from a sample of 111 subjects with a total of 319 rs-fMRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. A Dynamic Causal Model (DCM) is fit to the rs-fMRI scans to estimate effective brain connectivity within the DMN and related to a set of single nucleotide polymorphisms (SNPs) contained in an empirical disease-constrained set which is obtained out-of-sample from 663 ADNI subjects having only genome-wide data. We examine longitudinal data in both a 4-region and an 6-region network and relate longitudinal effective brain connectivity networks estimated using spectral DCM to SNPs using both linear mixed effect (LME) models as well as function-on-scalar regression (FSR). In the former case we implement a parametric bootstrap for testing SNP coefficients and make comparisons with p-values obtained from the chi-squared null distribution. We also implement a parametric bootstrap approach for testing regression functions in FSR and we make comparisons between p-values obtained from the parametric bootstrap to p-values obtained using the F-distribution with degreesof-freedom based on Satterthwaite's approximation.

Research paper thumbnail of Ultrasound-Guided Drainage of Breast Abscess

Scholars journal of applied medical sciences, Dec 12, 2022

Original Research Article Objective: To assess the efficacy of ultrasound-guided drainage of brea... more Original Research Article Objective: To assess the efficacy of ultrasound-guided drainage of breast abscesses with special attention to the risk of recurrence and the need for surgical treatment, to avoid postoperative morbidity, to reduce the hospital stay and cost of treatment, to determine the need for termination of breast feeding. Methods: 100 patients with breast were selected conveniently among those who were admitted in Dinajpur Medical College hospital or visited to surgery OPD with breast abscess. They were evaluated by short history, clinical examination and ultrasonogram. After counseling and taking consent they were treated with ultrasound-guided drainage, by needle or pigtail catheter under local anaesthesia. Follow-up punctures were performed at 2 or 3 day intervals until the clinical condition and ultrasound findings had improved. All patients were treated with oral antibiotics. Mammography was performed to search for underlying cancer. Results: Among the 100 cases included in the study, ninety-seven 97% patients with puerperal abscesses and 81% with non-puerperal abscesses recovered after the first round of ultrasound-guided drainage. One patient in each group had recurrence in loco but recovered after further ultrasound-guided drainage. Seven patients, 6 with nonpuerperal and 01 with puerperal abscesses, underwent surgical excision of the abscess cavity or fistulas. Breastfeeding continued and 23 patients were treated as outpatients. The median number of follow up examinations in the ultrasounddepartment was four (range 1-10) for the group of patients with puerperal abscess and three (range 1-7) in the group of patients with non-puerperal abscess. The corresponding figure for the median number of punctures was for both groups one (range 1-6 and 1-4). There were no reports of newly diagnosed breast cancer in the 1-year follow-up period. Conclusion: Treatment of breast abscess with US-guided Percutaneous aspiration or Pigtail catheter drainage both in puerperal and non-puerperal breast abscess has a high rate of success, no need to stop breast feeding, avoids postoperative morbidity, less hospital stay as well as cost of treatment.

Research paper thumbnail of Therapeutic Options in the Treatment of Clozapine-Induced Adverse Effects

Journal of Pharmacy Technology, 2004

Objective:To review the therapeutic options in the management of clozapine-induced adverse effect... more Objective:To review the therapeutic options in the management of clozapine-induced adverse effects.Data Sources:A MEDLINE search (from 1966 to present) was conducted, and English-language studies and review articles were retrieved to review the adverse effects of clozapine and their management.Study Selection and Data Extraction:All studies evaluating clozapine's adverse effects, such as agranulocytosis, seizures, neuroleptic malignant syndrome, hypersalivation, weight gain, sedation, fatigue, orthostatic hypotension, eosinophilia, delirium, new-onset diabetes, constipation, nausea, tachycardia, myocarditis, and pancreatitis, and their management were included.Data Synthesis:Clozapine, an atypical antipsychotic that has been proven effective and comparable, as well as superior, to conventional antipsychotics in treatment-resistant schizophrenia, is also being used in the treatment of a wide variety of other psychiatric conditions, including suicidal ideation, tardive dyskinesia,...