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Papers by lasanthi weerasooriya
Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Me... more Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Medical Association, June 2012 Colombo, Sri Lanka
Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Me... more Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Medical Association, June 2012 Colombo, Sri Lanka
The Journal of Pediatrics, 2013
Asian Journal of Pediatric Nephrology, 2021
Henoch–Schönlein purpura (HSP) nephritis (HSPN) and immunoglobulin A (IgA) nephropathy (IgAN) are... more Henoch–Schönlein purpura (HSP) nephritis (HSPN) and immunoglobulin A (IgA) nephropathy (IgAN) are related conditions that may be encountered sequentially in the same patient, are described in twins, and have common biological and pathological basis. The clinical features as well as the spectrum of severity at presentation vary significantly among patients. Here, we report a girl who first presented with acute glomerulonephritis and biopsy evidence of acute diffuse proliferative IgA nephritis with crescents, and 5 years later, she developed HSP and proteinuria. Such delayed appearance of cutaneous manifestations after initial renal involvement is unusual, though reported previously. This presentation stresses the importance of long-term follow-up of patients with HSPN and primary IgAN.
Asian Journal of Pediatric Nephrology, 2021
Background Introduction Childhood nephrotic syndrome follows a relapsing and remitting course. Co... more Background Introduction Childhood nephrotic syndrome follows a relapsing and remitting course. Corticosteroids are the mainstay of treatment and can be administered as a single early morning dose or as split doses. Usually, in the treatment of relapses, corticosteroids are administered daily until remission is achieved, followed by alternate day therapy. Early attainment of remission results in reduced morbidity and a reduced steroid burden. Objectives To compare the time duration to attain remission using a single dose versus a split dose regime of prednisolone in the treatment of relapses of childhood nephrotic syndrome. Methods Children between 1 and 14 years of age admitted to a tertiary care paediatric nephrology unit from August 2019 to February 2020 with a relapse of nephrotic syndrome were randomised to two groups. Patients in Group A received oral prednisolone at 60 mg/m2 as a single morning dose while those in Group B received the same total dose as two divided doses(2/3 m...
Sri Lanka Journal of Child Health
Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Me... more Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Medical Association, June 2012 Colombo, Sri Lanka
Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Me... more Poster Presentation Abstract (PP 16), 125th Anniversary Scientific Medical Congress, Sri Lanka Medical Association, June 2012 Colombo, Sri Lanka
The Journal of Pediatrics, 2013
Asian Journal of Pediatric Nephrology, 2021
Henoch–Schönlein purpura (HSP) nephritis (HSPN) and immunoglobulin A (IgA) nephropathy (IgAN) are... more Henoch–Schönlein purpura (HSP) nephritis (HSPN) and immunoglobulin A (IgA) nephropathy (IgAN) are related conditions that may be encountered sequentially in the same patient, are described in twins, and have common biological and pathological basis. The clinical features as well as the spectrum of severity at presentation vary significantly among patients. Here, we report a girl who first presented with acute glomerulonephritis and biopsy evidence of acute diffuse proliferative IgA nephritis with crescents, and 5 years later, she developed HSP and proteinuria. Such delayed appearance of cutaneous manifestations after initial renal involvement is unusual, though reported previously. This presentation stresses the importance of long-term follow-up of patients with HSPN and primary IgAN.
Asian Journal of Pediatric Nephrology, 2021
Background Introduction Childhood nephrotic syndrome follows a relapsing and remitting course. Co... more Background Introduction Childhood nephrotic syndrome follows a relapsing and remitting course. Corticosteroids are the mainstay of treatment and can be administered as a single early morning dose or as split doses. Usually, in the treatment of relapses, corticosteroids are administered daily until remission is achieved, followed by alternate day therapy. Early attainment of remission results in reduced morbidity and a reduced steroid burden. Objectives To compare the time duration to attain remission using a single dose versus a split dose regime of prednisolone in the treatment of relapses of childhood nephrotic syndrome. Methods Children between 1 and 14 years of age admitted to a tertiary care paediatric nephrology unit from August 2019 to February 2020 with a relapse of nephrotic syndrome were randomised to two groups. Patients in Group A received oral prednisolone at 60 mg/m2 as a single morning dose while those in Group B received the same total dose as two divided doses(2/3 m...
Sri Lanka Journal of Child Health