leila azimian - Academia.edu (original) (raw)

Papers by leila azimian

Research paper thumbnail of Continuous cultivation of <scp><i>Debaryomyces hansenii</i></scp> (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Continuous cultivation of Debaryomyces hansenii (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Water and Environment Journal, Feb 26, 2023

Desalter effluent (DE) is typically discharged into a petroleum wastewater treatment plant, but i... more Desalter effluent (DE) is typically discharged into a petroleum wastewater treatment plant, but its high salt concentration deteriorates the biological treatment. This study used various dilution rates to investigate the treatment of a synthetic DE containing dodecane under saline conditions using a halotolerant yeast, Debaryomyces hansenii, to determine the optimum substrate concentration for use in continuous stirred‐tank reactors (CSTRs). A literature review indicated that this study was the first to examine the biological treatment of DE using D. hansenii in a CSTR system. At a low dodecane substrate concentration, DE did not inhibit D. hansenii growth, and the experimental data approached the Monod model, with μmax and Ks selected as 0.08 h−1 and 1575 mg L−1, respectively. The optimum removal of chemical oxygen demand (95.7% and 85%) was obtained at dilution rates of 0.007 and 0.026 d−1. Using D. hansenii in a CSTR system appeared to be a sustainable approach for the biological treatment of DE. Scale‐up of these laboratory findings to the industrial scale is required to confirm that petroleum DE can be treated using equalization and filtration tanks as a continuous bioreactor. Adjusting the dilution rate can provide sufficient time for biodegradation and hydrocarbon removal from high salt DE by halotolerant yeasts like D. hansenii.

Research paper thumbnail of Response surface methodology ( <scp>RMS</scp> ) modelling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Response surface methodology ( RMS ) modelling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Canadian Journal of Chemical Engineering, Jan 26, 2023

Research paper thumbnail of Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Research paper thumbnail of Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Cell Biochemistry and Function, Feb 13, 2023

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Authorea (Authorea), May 26, 2022

Research paper thumbnail of Investigation of growth kinetics of<i>Debaryomyces hansenii</i>(LAF‐3 10 U) in petroleum refinery desalter effluent

Investigation of growth kinetics ofDebaryomyces hansenii(LAF‐3 10 U) in petroleum refinery desalter effluent

Canadian Journal of Chemical Engineering, Nov 2, 2018

Desalter effluent is a difficult to treat wastewater stream emerging from petroleum refining oper... more Desalter effluent is a difficult to treat wastewater stream emerging from petroleum refining operations. In this study, an osmotolerant and halotolerant yeast, Debaryomyces hansenii, was investigated for the first time for its use in removing phenol from simulated and actual desalter effluent. D. hansenii was able to degrade phenols at substrate COD concentrations ranging from 300–1200 mg L−1, whereas the substrate inhibition was noted as COD increased from 2000–4000 mg L−1. Three kinetic models (Andrews, Aiba, and Edward) were applied as unstructured mathematical models to simulate substrate inhibition kinetics with respect to phenol COD. Among all models, the Edward model best simulated the yeast growth on phenol. Using the Edward model, the model parameters were μmax 0.21 h−1, KS 633.95 mg · L−1, and KI 1263.61 mg · L−1, respectively. The results in this study confirmed that D. hansenii has a high tolerance toward phenols and other organic compounds and salt found in desalter effluent. This yeast is therefore suggested to serve as an appropriate system from biological treatment of phenolic wastes in difficult to treat effluents such as desalter effluent.

Research paper thumbnail of Bioremediation of Refinery Desalter Effluent using Debaryomyces hansenii and Parachlorella kessleri

Crude oil desalting operations produce an effluent stream which is challenging to treat due to it... more Crude oil desalting operations produce an effluent stream which is challenging to treat due to its salt, heavy metal and hydrocarbon content. Consequently, desalter effluent (DE) is usually diluted into other effluent streams and sent to conventional wastewater treatment plants which may lead to upsets the plant operation.

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Cell Biochemistry and Function

Research paper thumbnail of Response surface methodology ( <scp>RMS</scp> ) modelling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Response surface methodology ( RMS ) modelling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Canadian Journal of Chemical Engineering, Dec 8, 2022

Research paper thumbnail of Continuous cultivation of Debaryomyces hansenii (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Continuous cultivation of Debaryomyces hansenii (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Water and Environment Journal

Research paper thumbnail of Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Research paper thumbnail of Author response for "Response surface methodology ( RMS ) modeling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Author response for "Response surface methodology ( RMS ) modeling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Research paper thumbnail of Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Research paper thumbnail of Bioremediation of Refinery Desalter Effluent using Debaryomyces hansenii and Parachlorella kessleri

Bioremediation of Refinery Desalter Effluent using Debaryomyces hansenii and Parachlorella kessleri

Research paper thumbnail of Synthesis, physical characterization, antibacterial activity and thermodynamic studies of five coodrdinate cobalt(III) Schiff base complexes

Bulletin of the Chemical Society of Ethiopia, 2016

Some five-coordinated cobalt(III) complexes were synthesized and characterized using elemental an... more Some five-coordinated cobalt(III) complexes were synthesized and characterized using elemental analysis, 1 H NMR and IR spectra. The formation constants and the thermodynamic parameters were measured spectrophotometrically for the 1:1 adduct formation of [Co(Chel)(PBu3)]ClO4.H2O where Chel = cd3OMesalen, cd4OMesalen, cd5OMesalen: methyl-2-{[1-methyl-2-(2-hydroxy-3-, 4-, 5-methoxyphenyl)methylidynenitrilo]ethyl}amino-1-cyclopentene-dithiocarboxylate, as acceptors, with some linear and cyclic amines as donors, in different solvents at constant ionic strength (I = 0.1 M NaClO4), and at various temperatures (T = 283-313 K). The results revealed that the formation constants of the Co(III) Schiff base complexes toward a given amines donor are as follow: [Co(cd4OMesalMeen)(PBu3)] + > [Co(cd3OMesalMeen)(PBu3)] + > [Co(cd5OMesalMeen)(PBu3)] +. The trend of the formation constants of the donors (amines) toward a given cobalt(III) complex is as follow: Im > 4-MeIm > BzIm and n-butylamine > sec-butylamine > tert-butylamine. Also the effect of the solvents on the formation constants of a given cobalt(III) Schiff base complex toward a given donor are as follow: CH3CN > DMF > EtOH. The ligands and their cobalt complexes have been screened for their antibacterial activities. All the free Schiff base ligands exhibit higher antibacterial activity than the cobalt(III) complexes.

Research paper thumbnail of Investigation of growth kinetics of Debaryomyces hansenii (LAF-3 10 U) in petroleum refinery desalter effluent

Investigation of growth kinetics of Debaryomyces hansenii (LAF-3 10 U) in petroleum refinery desalter effluent

The Canadian Journal of Chemical Engineering, Nov 2, 2018

Research paper thumbnail of Continuous cultivation of <scp><i>Debaryomyces hansenii</i></scp> (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Continuous cultivation of Debaryomyces hansenii (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Water and Environment Journal, Feb 26, 2023

Desalter effluent (DE) is typically discharged into a petroleum wastewater treatment plant, but i... more Desalter effluent (DE) is typically discharged into a petroleum wastewater treatment plant, but its high salt concentration deteriorates the biological treatment. This study used various dilution rates to investigate the treatment of a synthetic DE containing dodecane under saline conditions using a halotolerant yeast, Debaryomyces hansenii, to determine the optimum substrate concentration for use in continuous stirred‐tank reactors (CSTRs). A literature review indicated that this study was the first to examine the biological treatment of DE using D. hansenii in a CSTR system. At a low dodecane substrate concentration, DE did not inhibit D. hansenii growth, and the experimental data approached the Monod model, with μmax and Ks selected as 0.08 h−1 and 1575 mg L−1, respectively. The optimum removal of chemical oxygen demand (95.7% and 85%) was obtained at dilution rates of 0.007 and 0.026 d−1. Using D. hansenii in a CSTR system appeared to be a sustainable approach for the biological treatment of DE. Scale‐up of these laboratory findings to the industrial scale is required to confirm that petroleum DE can be treated using equalization and filtration tanks as a continuous bioreactor. Adjusting the dilution rate can provide sufficient time for biodegradation and hydrocarbon removal from high salt DE by halotolerant yeasts like D. hansenii.

Research paper thumbnail of Response surface methodology ( <scp>RMS</scp> ) modelling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Response surface methodology ( RMS ) modelling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Canadian Journal of Chemical Engineering, Jan 26, 2023

Research paper thumbnail of Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Research paper thumbnail of Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Cell Biochemistry and Function, Feb 13, 2023

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Authorea (Authorea), May 26, 2022

Research paper thumbnail of Investigation of growth kinetics of<i>Debaryomyces hansenii</i>(LAF‐3 10 U) in petroleum refinery desalter effluent

Investigation of growth kinetics ofDebaryomyces hansenii(LAF‐3 10 U) in petroleum refinery desalter effluent

Canadian Journal of Chemical Engineering, Nov 2, 2018

Desalter effluent is a difficult to treat wastewater stream emerging from petroleum refining oper... more Desalter effluent is a difficult to treat wastewater stream emerging from petroleum refining operations. In this study, an osmotolerant and halotolerant yeast, Debaryomyces hansenii, was investigated for the first time for its use in removing phenol from simulated and actual desalter effluent. D. hansenii was able to degrade phenols at substrate COD concentrations ranging from 300–1200 mg L−1, whereas the substrate inhibition was noted as COD increased from 2000–4000 mg L−1. Three kinetic models (Andrews, Aiba, and Edward) were applied as unstructured mathematical models to simulate substrate inhibition kinetics with respect to phenol COD. Among all models, the Edward model best simulated the yeast growth on phenol. Using the Edward model, the model parameters were μmax 0.21 h−1, KS 633.95 mg · L−1, and KI 1263.61 mg · L−1, respectively. The results in this study confirmed that D. hansenii has a high tolerance toward phenols and other organic compounds and salt found in desalter effluent. This yeast is therefore suggested to serve as an appropriate system from biological treatment of phenolic wastes in difficult to treat effluents such as desalter effluent.

Research paper thumbnail of Bioremediation of Refinery Desalter Effluent using Debaryomyces hansenii and Parachlorella kessleri

Crude oil desalting operations produce an effluent stream which is challenging to treat due to it... more Crude oil desalting operations produce an effluent stream which is challenging to treat due to its salt, heavy metal and hydrocarbon content. Consequently, desalter effluent (DE) is usually diluted into other effluent streams and sent to conventional wastewater treatment plants which may lead to upsets the plant operation.

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy

Cell Biochemistry and Function

Research paper thumbnail of Response surface methodology ( <scp>RMS</scp> ) modelling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Response surface methodology ( RMS ) modelling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Canadian Journal of Chemical Engineering, Dec 8, 2022

Research paper thumbnail of Continuous cultivation of Debaryomyces hansenii (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Continuous cultivation of Debaryomyces hansenii (LAF‐3 10 U) on dodecane in synthetic desalter effluent at varying dilution rates on dodecane

Water and Environment Journal

Research paper thumbnail of Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Author response for "Response surface methodology ( <scp>RMS</scp> ) modeling to improve <i>n</i> ‐dodecane degradation using <i>Debaryomyces hansenii</i> <scp>LAF</scp> ‐3 in a simulated desalter effluent

Research paper thumbnail of Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for type 2 diabetes therapy Corresponding author: Lidan You. Professor at the University of Toronto in the Department of Mechanical Engineering & Institute of Biomedical Engineering

Research paper thumbnail of Author response for "Response surface methodology ( RMS ) modeling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Author response for "Response surface methodology ( RMS ) modeling to improve n ‐dodecane degradation using Debaryomyces hansenii LAF ‐3 in a simulated desalter effluent

Research paper thumbnail of Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Investigation of Hydrocarbon Utilization By Debaryomyces Hansenii (LAF-3 10 u) in Desalter Effluent

Research paper thumbnail of Bioremediation of Refinery Desalter Effluent using Debaryomyces hansenii and Parachlorella kessleri

Bioremediation of Refinery Desalter Effluent using Debaryomyces hansenii and Parachlorella kessleri

Research paper thumbnail of Synthesis, physical characterization, antibacterial activity and thermodynamic studies of five coodrdinate cobalt(III) Schiff base complexes

Bulletin of the Chemical Society of Ethiopia, 2016

Some five-coordinated cobalt(III) complexes were synthesized and characterized using elemental an... more Some five-coordinated cobalt(III) complexes were synthesized and characterized using elemental analysis, 1 H NMR and IR spectra. The formation constants and the thermodynamic parameters were measured spectrophotometrically for the 1:1 adduct formation of [Co(Chel)(PBu3)]ClO4.H2O where Chel = cd3OMesalen, cd4OMesalen, cd5OMesalen: methyl-2-{[1-methyl-2-(2-hydroxy-3-, 4-, 5-methoxyphenyl)methylidynenitrilo]ethyl}amino-1-cyclopentene-dithiocarboxylate, as acceptors, with some linear and cyclic amines as donors, in different solvents at constant ionic strength (I = 0.1 M NaClO4), and at various temperatures (T = 283-313 K). The results revealed that the formation constants of the Co(III) Schiff base complexes toward a given amines donor are as follow: [Co(cd4OMesalMeen)(PBu3)] + > [Co(cd3OMesalMeen)(PBu3)] + > [Co(cd5OMesalMeen)(PBu3)] +. The trend of the formation constants of the donors (amines) toward a given cobalt(III) complex is as follow: Im > 4-MeIm > BzIm and n-butylamine > sec-butylamine > tert-butylamine. Also the effect of the solvents on the formation constants of a given cobalt(III) Schiff base complex toward a given donor are as follow: CH3CN > DMF > EtOH. The ligands and their cobalt complexes have been screened for their antibacterial activities. All the free Schiff base ligands exhibit higher antibacterial activity than the cobalt(III) complexes.

Research paper thumbnail of Investigation of growth kinetics of Debaryomyces hansenii (LAF-3 10 U) in petroleum refinery desalter effluent

Investigation of growth kinetics of Debaryomyces hansenii (LAF-3 10 U) in petroleum refinery desalter effluent

The Canadian Journal of Chemical Engineering, Nov 2, 2018