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Technologie durchsetzen kann. Daher wurden im Wetlab Dummy-Tests für die Ergonomie-und Kadavertes... more Technologie durchsetzen kann. Daher wurden im Wetlab Dummy-Tests für die Ergonomie-und Kadavertests für die Simulation "realer" Operationen im Bereich der Mund-, Kiefer-und Gesichtsheilkunde durchgeführt. Es wurden verschiedene makroretentive Osteotomiemuster in Ober-und Unterkiefern durchgeführt wurden. Es konnte gezeigt werden, dass unser Prototyp Vorteile gegenüber dem Stand der heutigen Tools aufweist, z. B. weniger Knochenverlust, präzise und in Echtzeit navigierte Ausführung von vordefinierten Geometrien von frei gewählten Schnittmustern. Dank der freien Wahl an verschiedenen Schnittmustern sehen wir eine weitere Einsatzmöglichkeit des Prototyps in der Craniosynostose Chirurgie. Wir führten eine Finite Element Method Untersuchung durch, um unvollständige Osteotomien auf der Innenseite eines virtuell rekonstruierten Knochendeckels zu simulieren, um die Verformung des Knochens zu erleichtern. Mit diesen biomechanischen Analysen wurden Grundkenntnisse über das beste Verhältnis zwischen Belastung und Kraft zu erlangen, um eine beste mögliche Vergrösserung der projizierten Knochenoberfläche zu erhalten. Schlussendlich steht eine multizentrische Studie am Menschen für die klinische Einführung des Prototyps bereit, um weitere Erfahrungen und Informationen für die zukünftige Arbeit zu sammeln.
Usporedba intramuskularno primijenjenog i inhaliranog epinefrina: eksperimentalno istraživanje A ... more Usporedba intramuskularno primijenjenog i inhaliranog epinefrina: eksperimentalno istraživanje A Comparison of Intramuscular Versus Inhaled Epinephrine in Humans: A Pilot Study Sažetak Svrha: Intravenozna ili intramuskularna primjena epinefrina preporučuje se u slučaju sistemske anafilaksije. Zadatak je bio procijeniti njegovu razinu u plazmi nakon intramuskularne primjene u mišić bukcinator u odnosu prema razini nakon inhalacije. Ispitanici i postupci: U ovom eksperimentalnom istraživanju na ljudima mjerile su se koncentracije epinefrina prije intramuskularne primjene ili inhalacije te nakon njih, uz intramuskularnu injekciju fiziološke otopine te intravenoznu primjenu epinefrina kao negativnu i pozitivnu kontrolu. Rezultati: Najviše vrijednosti bile su nakon intramuskularne primjene -maksimalna razina u plazmi iznosila je 3367,2 pg/ml. Nakon inhalacije epinefrina razina je bila 151,89 pg/ml. Zaključak: U slučaju respiratornog poremećaja, ako je uzrok anafilaksija, može biti korisn...
Der Bruch einer Injektionsnadel ist in der zahnarztlichen Praxis ein eher seltenes, aber hinsicht... more Der Bruch einer Injektionsnadel ist in der zahnarztlichen Praxis ein eher seltenes, aber hinsichtlich moglicher Folgerisiken nicht zu unterschatzendes Ereignis. Beschrieben wird der Fall eines Patienten, der von seinem Hauszahnarzt zur Entfernung einer abgebrochenen Nadelspitze uberwiesen wurde. Fur diese Art von Zwischenfall werden verschiedene Ursachen diskutiert, zum Nadelbruch kommt es jedoch vielfach, weil eine fur die jeweilige Anatomie zu kurze und zu dunne Injektionsnadel verwendet wird. Ausschlaggebend fur eine minimalinvasive Entfernung der abgebrochenen Nadelspitze ist eine exakte pra- und intraoperative Lokalisierung. Im vorliegenden Fall konnte dies mittels Computertomographie und Durchleuchtung erreicht werden. Der Leser erhalt einen Uberblick uber die Verhaltensmasnahmen vor und wahrend einer Injektion sowie uber das Vorgehen bei Eintreten einer solchen Komplikation.
the Quintessence, 2011
La rotura de una aguja para inyeccion es un acontecimiento relativamente raro en la consulta dent... more La rotura de una aguja para inyeccion es un acontecimiento relativamente raro en la consulta dental, pero que no debe ser subestimado sobre todo por las posibles consecuencias. Se describe el caso de un paciente remitido por su odontologo de cabecera a nuestro centro para la extraccion de una punta de aguja fracturada. Se barajan diversas causas para este tipo de incidentes, pero en muchos casos, la rotura de la aguja se debe al uso de agujas demasiado cortas o demasiado finas para unas condiciones anatomicas determinadas. Un aspecto esencial para la extraccion minimamente invasiva de la punta fracturada es la localizacion preoperatoria e intraoperatoria exacta. En este caso, se localizo el objeto mediante una tomografia computarizada y una fluoroscopia. Se ofrece al lector una perspectiva global de las medidas que tomar antes y durante la inyeccion, asi como la forma de proceder en caso de hallarse ante una complicacion de este tipo.
Journal of dentistry for children, 2020
Neuroblastoma is a malignant embryonal tumor derived from the neural crest cells of the sympathet... more Neuroblastoma is a malignant embryonal tumor derived from the neural crest cells of the sympathetic nervous system. Curative therapy is challenging, especially because early-stage diagnosis in toddlers is difficult. Successful treatment of high-risk neuroblastoma is only achieved in approximately half of the cases and requires an immediate interdisciplinary approach. We present a 34-month-old toddler with swelling of the left side of the face of three days duration and a mandibular mass of unknown duration, which was diagnosed as a metastasis of a neuroblastoma. He also had metastases in the kidney, long bones and skull. Despite the poor prognosis in cases of disseminated skeletal involvement and N-myc amplification, the young patient remained free of recurrence during a follow-up period of 36 months after multidisciplinary treatment. The purpose of this case report is to increase awareness of the clinical features of neuroblastoma among pediatric dentists to support early-stage dia...
Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 2009
The purpose of this study was to determine the anesthetic efficacy of a intraosseous anesthesia (... more The purpose of this study was to determine the anesthetic efficacy of a intraosseous anesthesia (IOA) as an alternative to the infra alveolar nerve block (IANB) or the maxillary anesthesia. 55 subjects who underwent a tooth extraction received a primary X-tip intraosseous injection (LLC Lakewood, New Jersey, U.S.A.) of Ubistesin forte (articaini hydrochloridum 40 mg, adrenalinum 10 pg ut adrenalini hydrochloridum 1:100000, median 1.5 ml). A pulse oximeter measured the heart rate and the oxygen saturation. The results demonstrated, that the maximum heart rate was higher with the intraosseous injection (average 14.6 beats/min increase) during 1.5-2 minutes, but there was no depression of the oxygen saturation. The wound healing was uneventful. We registered five non-responders which were treated additionally with 1.3 ml of Ubistesin forte terminal anesthesia. For all patients the IOA was unpleasant similar to a "normal" anesthesia. Success of the intraosseous injection was 9...
Adresa za dopisivanje Dr. med. dent. et pract. med. M. Augello Plattenstrasse 15 8032 Zurich Svic... more Adresa za dopisivanje Dr. med. dent. et pract. med. M. Augello Plattenstrasse 15 8032 Zurich Svicarska Tel. +41 44 634 32 90 Fax +41 44 634 43 28 www.augello@gmx.ch Sažetak Svrha: Intravenozna ili intramuskularna primjena epinefrina preporucuje se u slucaju sistemske anafilaksije. Zadatak je bio procijeniti njegovu razinu u plazmi nakon intramuskularne primjene u misic bukcinator u odnosu prema razini nakon inhalacije. Ispitanici i postupci: U ovom eksperimentalnom istraživanju na ljudima mjerile su se koncentracije epinefrina prije intramuskularne primjene ili inhalacije te nakon njih, uz intramuskularnu injekciju fizioloske otopine te intravenoznu primjenu epinefrina kao negativnu i pozitivnu kontrolu. Rezultati: Najvise vrijednosti bile su nakon intramuskularne primjene maksimalna razina u plazmi iznosila je 3367,2 pg/ml. Nakon inhalacije epinefrina razina je bila 151,89 pg/ml. Zakljucak: U slucaju respiratornog poremecaja, ako je uzrok anafilaksija, može biti korisna inhalacijsk...
Journal of Clinical Medicine, 2021
Background: In order to overcome the geometrical and physical limitations of conventional rotatin... more Background: In order to overcome the geometrical and physical limitations of conventional rotating and piezosurgery instruments used to perform bone osteotomies, as well as the difficulties in translating digital planning to the operating room, a stand-alone robot-guided laser system has been developed by Advanced Osteotomy Tools, a Swiss start-up company. We present our experiences of the first-in-man use of the Cold Ablation Robot-guided Laser Osteotome (CARLO®). Methods: The CARLO® device employs a stand-alone 2.94-µm erbium-doped yttrium aluminum garnet (Er:YAG) laser mounted on a robotic arm. A 19-year-old patient provided informed consent to undergo bimaxillary orthognathic surgery. A linear Le Fort I midface osteotomy was digitally planned and transferred to the CARLO® device. The linear part of the Le Fort I osteotomy was performed autonomously by the CARLO® device under direct visual control. All pre-, intra-, and postoperative technical difficulties and safety issues were ...
International Journal of Oral and Maxillofacial Surgery, 2017
Oral Diseases, 2021
Mucormycosis (formerly synonym zygomycosis) is a rare and potentially fatal invasive fungal infec... more Mucormycosis (formerly synonym zygomycosis) is a rare and potentially fatal invasive fungal infection caused by the Mucorales order, to which the species Rhizopus spp, Mucor spp, Rhizomucor
Annals of Medicine and Surgery
Lasers in Surgery and Medicine
Journal of Craniofacial Surgery
Journal of Cranio-Maxillofacial Surgery
Lasers in Medical Science
Oral and Maxillofacial Surgery Cases
Dentistry Journal, 2016
Background: Bisphosphonate-associated osteonecrosis of the jaws (MRONJ/BP-ONJ/ BRONJ) is a common... more Background: Bisphosphonate-associated osteonecrosis of the jaws (MRONJ/BP-ONJ/ BRONJ) is a commonly seen disease. During recent decades, major advances in diagnostics have occurred. Once the clinical picture shows typical MRONJ features, imaging is necessary to determine the size of the lesion. Exposed bone is not always painful, therefore a thorough clinical examination and radiological imaging are essential when MRONJ is suspected. Methods: In this paper we will present the latest clinical update on the imaging options in regard to MRONJ: X-ray/Panoramic Radiograph, Cone Beam Computed Tomography (CBCT) and Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Nuclear Imaging, Fluorescence-Guided Bone Resection. Conclusion: Which image modality is chosen depends not only on the surgeon's/practitioner's preference but also on the available imaging modalities. A three-dimensional imaging modality is desirable, and in severe cases necessary, for extended resections and planning of reconstruction.
Quintessence Publicacion Internacional De Odontologia, 2011
Technologie durchsetzen kann. Daher wurden im Wetlab Dummy-Tests für die Ergonomie-und Kadavertes... more Technologie durchsetzen kann. Daher wurden im Wetlab Dummy-Tests für die Ergonomie-und Kadavertests für die Simulation "realer" Operationen im Bereich der Mund-, Kiefer-und Gesichtsheilkunde durchgeführt. Es wurden verschiedene makroretentive Osteotomiemuster in Ober-und Unterkiefern durchgeführt wurden. Es konnte gezeigt werden, dass unser Prototyp Vorteile gegenüber dem Stand der heutigen Tools aufweist, z. B. weniger Knochenverlust, präzise und in Echtzeit navigierte Ausführung von vordefinierten Geometrien von frei gewählten Schnittmustern. Dank der freien Wahl an verschiedenen Schnittmustern sehen wir eine weitere Einsatzmöglichkeit des Prototyps in der Craniosynostose Chirurgie. Wir führten eine Finite Element Method Untersuchung durch, um unvollständige Osteotomien auf der Innenseite eines virtuell rekonstruierten Knochendeckels zu simulieren, um die Verformung des Knochens zu erleichtern. Mit diesen biomechanischen Analysen wurden Grundkenntnisse über das beste Verhältnis zwischen Belastung und Kraft zu erlangen, um eine beste mögliche Vergrösserung der projizierten Knochenoberfläche zu erhalten. Schlussendlich steht eine multizentrische Studie am Menschen für die klinische Einführung des Prototyps bereit, um weitere Erfahrungen und Informationen für die zukünftige Arbeit zu sammeln.
Usporedba intramuskularno primijenjenog i inhaliranog epinefrina: eksperimentalno istraživanje A ... more Usporedba intramuskularno primijenjenog i inhaliranog epinefrina: eksperimentalno istraživanje A Comparison of Intramuscular Versus Inhaled Epinephrine in Humans: A Pilot Study Sažetak Svrha: Intravenozna ili intramuskularna primjena epinefrina preporučuje se u slučaju sistemske anafilaksije. Zadatak je bio procijeniti njegovu razinu u plazmi nakon intramuskularne primjene u mišić bukcinator u odnosu prema razini nakon inhalacije. Ispitanici i postupci: U ovom eksperimentalnom istraživanju na ljudima mjerile su se koncentracije epinefrina prije intramuskularne primjene ili inhalacije te nakon njih, uz intramuskularnu injekciju fiziološke otopine te intravenoznu primjenu epinefrina kao negativnu i pozitivnu kontrolu. Rezultati: Najviše vrijednosti bile su nakon intramuskularne primjene -maksimalna razina u plazmi iznosila je 3367,2 pg/ml. Nakon inhalacije epinefrina razina je bila 151,89 pg/ml. Zaključak: U slučaju respiratornog poremećaja, ako je uzrok anafilaksija, može biti korisn...
Der Bruch einer Injektionsnadel ist in der zahnarztlichen Praxis ein eher seltenes, aber hinsicht... more Der Bruch einer Injektionsnadel ist in der zahnarztlichen Praxis ein eher seltenes, aber hinsichtlich moglicher Folgerisiken nicht zu unterschatzendes Ereignis. Beschrieben wird der Fall eines Patienten, der von seinem Hauszahnarzt zur Entfernung einer abgebrochenen Nadelspitze uberwiesen wurde. Fur diese Art von Zwischenfall werden verschiedene Ursachen diskutiert, zum Nadelbruch kommt es jedoch vielfach, weil eine fur die jeweilige Anatomie zu kurze und zu dunne Injektionsnadel verwendet wird. Ausschlaggebend fur eine minimalinvasive Entfernung der abgebrochenen Nadelspitze ist eine exakte pra- und intraoperative Lokalisierung. Im vorliegenden Fall konnte dies mittels Computertomographie und Durchleuchtung erreicht werden. Der Leser erhalt einen Uberblick uber die Verhaltensmasnahmen vor und wahrend einer Injektion sowie uber das Vorgehen bei Eintreten einer solchen Komplikation.
the Quintessence, 2011
La rotura de una aguja para inyeccion es un acontecimiento relativamente raro en la consulta dent... more La rotura de una aguja para inyeccion es un acontecimiento relativamente raro en la consulta dental, pero que no debe ser subestimado sobre todo por las posibles consecuencias. Se describe el caso de un paciente remitido por su odontologo de cabecera a nuestro centro para la extraccion de una punta de aguja fracturada. Se barajan diversas causas para este tipo de incidentes, pero en muchos casos, la rotura de la aguja se debe al uso de agujas demasiado cortas o demasiado finas para unas condiciones anatomicas determinadas. Un aspecto esencial para la extraccion minimamente invasiva de la punta fracturada es la localizacion preoperatoria e intraoperatoria exacta. En este caso, se localizo el objeto mediante una tomografia computarizada y una fluoroscopia. Se ofrece al lector una perspectiva global de las medidas que tomar antes y durante la inyeccion, asi como la forma de proceder en caso de hallarse ante una complicacion de este tipo.
Journal of dentistry for children, 2020
Neuroblastoma is a malignant embryonal tumor derived from the neural crest cells of the sympathet... more Neuroblastoma is a malignant embryonal tumor derived from the neural crest cells of the sympathetic nervous system. Curative therapy is challenging, especially because early-stage diagnosis in toddlers is difficult. Successful treatment of high-risk neuroblastoma is only achieved in approximately half of the cases and requires an immediate interdisciplinary approach. We present a 34-month-old toddler with swelling of the left side of the face of three days duration and a mandibular mass of unknown duration, which was diagnosed as a metastasis of a neuroblastoma. He also had metastases in the kidney, long bones and skull. Despite the poor prognosis in cases of disseminated skeletal involvement and N-myc amplification, the young patient remained free of recurrence during a follow-up period of 36 months after multidisciplinary treatment. The purpose of this case report is to increase awareness of the clinical features of neuroblastoma among pediatric dentists to support early-stage dia...
Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 2009
The purpose of this study was to determine the anesthetic efficacy of a intraosseous anesthesia (... more The purpose of this study was to determine the anesthetic efficacy of a intraosseous anesthesia (IOA) as an alternative to the infra alveolar nerve block (IANB) or the maxillary anesthesia. 55 subjects who underwent a tooth extraction received a primary X-tip intraosseous injection (LLC Lakewood, New Jersey, U.S.A.) of Ubistesin forte (articaini hydrochloridum 40 mg, adrenalinum 10 pg ut adrenalini hydrochloridum 1:100000, median 1.5 ml). A pulse oximeter measured the heart rate and the oxygen saturation. The results demonstrated, that the maximum heart rate was higher with the intraosseous injection (average 14.6 beats/min increase) during 1.5-2 minutes, but there was no depression of the oxygen saturation. The wound healing was uneventful. We registered five non-responders which were treated additionally with 1.3 ml of Ubistesin forte terminal anesthesia. For all patients the IOA was unpleasant similar to a "normal" anesthesia. Success of the intraosseous injection was 9...
Adresa za dopisivanje Dr. med. dent. et pract. med. M. Augello Plattenstrasse 15 8032 Zurich Svic... more Adresa za dopisivanje Dr. med. dent. et pract. med. M. Augello Plattenstrasse 15 8032 Zurich Svicarska Tel. +41 44 634 32 90 Fax +41 44 634 43 28 www.augello@gmx.ch Sažetak Svrha: Intravenozna ili intramuskularna primjena epinefrina preporucuje se u slucaju sistemske anafilaksije. Zadatak je bio procijeniti njegovu razinu u plazmi nakon intramuskularne primjene u misic bukcinator u odnosu prema razini nakon inhalacije. Ispitanici i postupci: U ovom eksperimentalnom istraživanju na ljudima mjerile su se koncentracije epinefrina prije intramuskularne primjene ili inhalacije te nakon njih, uz intramuskularnu injekciju fizioloske otopine te intravenoznu primjenu epinefrina kao negativnu i pozitivnu kontrolu. Rezultati: Najvise vrijednosti bile su nakon intramuskularne primjene maksimalna razina u plazmi iznosila je 3367,2 pg/ml. Nakon inhalacije epinefrina razina je bila 151,89 pg/ml. Zakljucak: U slucaju respiratornog poremecaja, ako je uzrok anafilaksija, može biti korisna inhalacijsk...
Journal of Clinical Medicine, 2021
Background: In order to overcome the geometrical and physical limitations of conventional rotatin... more Background: In order to overcome the geometrical and physical limitations of conventional rotating and piezosurgery instruments used to perform bone osteotomies, as well as the difficulties in translating digital planning to the operating room, a stand-alone robot-guided laser system has been developed by Advanced Osteotomy Tools, a Swiss start-up company. We present our experiences of the first-in-man use of the Cold Ablation Robot-guided Laser Osteotome (CARLO®). Methods: The CARLO® device employs a stand-alone 2.94-µm erbium-doped yttrium aluminum garnet (Er:YAG) laser mounted on a robotic arm. A 19-year-old patient provided informed consent to undergo bimaxillary orthognathic surgery. A linear Le Fort I midface osteotomy was digitally planned and transferred to the CARLO® device. The linear part of the Le Fort I osteotomy was performed autonomously by the CARLO® device under direct visual control. All pre-, intra-, and postoperative technical difficulties and safety issues were ...
International Journal of Oral and Maxillofacial Surgery, 2017
Oral Diseases, 2021
Mucormycosis (formerly synonym zygomycosis) is a rare and potentially fatal invasive fungal infec... more Mucormycosis (formerly synonym zygomycosis) is a rare and potentially fatal invasive fungal infection caused by the Mucorales order, to which the species Rhizopus spp, Mucor spp, Rhizomucor
Annals of Medicine and Surgery
Lasers in Surgery and Medicine
Journal of Craniofacial Surgery
Journal of Cranio-Maxillofacial Surgery
Lasers in Medical Science
Oral and Maxillofacial Surgery Cases
Dentistry Journal, 2016
Background: Bisphosphonate-associated osteonecrosis of the jaws (MRONJ/BP-ONJ/ BRONJ) is a common... more Background: Bisphosphonate-associated osteonecrosis of the jaws (MRONJ/BP-ONJ/ BRONJ) is a commonly seen disease. During recent decades, major advances in diagnostics have occurred. Once the clinical picture shows typical MRONJ features, imaging is necessary to determine the size of the lesion. Exposed bone is not always painful, therefore a thorough clinical examination and radiological imaging are essential when MRONJ is suspected. Methods: In this paper we will present the latest clinical update on the imaging options in regard to MRONJ: X-ray/Panoramic Radiograph, Cone Beam Computed Tomography (CBCT) and Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Nuclear Imaging, Fluorescence-Guided Bone Resection. Conclusion: Which image modality is chosen depends not only on the surgeon's/practitioner's preference but also on the available imaging modalities. A three-dimensional imaging modality is desirable, and in severe cases necessary, for extended resections and planning of reconstruction.
Quintessence Publicacion Internacional De Odontologia, 2011