marta eusebio - Academia.edu (original) (raw)

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Papers by marta eusebio

Research paper thumbnail of Olmesartan-Induced Enteropathy: An Unusual Cause of Villous Atrophy

GE Portuguese Journal of Gastroenterology, 2016

We report a case of a 63-year-old-man presenting with chronic diarrhea and weight loss while on o... more We report a case of a 63-year-old-man presenting with chronic diarrhea and weight loss while on olmesartan treatment for hypertension. Investigation showed multiple nutritional deficiencies associated with diffuse intestinal villous atrophy. Serologies for celiac disease were negative and other causes of villous atrophy were excluded. Olmesartan as a precipitant agent was suspected and withdrawn. Clinical improvement occurred in days with no need for other therapeutic measures. Follow-up at three months showed clinical remission and almost complete recovery of intestinal atrophy. Olmesartan is an angiotensin receptor blocker commonly prescribed for the management of hypertension. Spruelike enteropathy associated with this drug is a recently described entity with few cases reported. It presents with chronic diarrhea and intestinal villous atrophy and should be included in its differential diagnosis. This case intends to alert clinicians for the possibility of this event in a patient on treatment with this drug.

Research paper thumbnail of Intraluminal Duodenal (“Windsock”) Diverticulum: A Rare Cause of Gastrointestinal Bleeding

GE Portuguese Journal of Gastroenterology, 2016

Research paper thumbnail of Risk factors for severity and recurrence of colonic diverticular bleeding

Revista Española de Enfermedades Digestivas, 2016

Research paper thumbnail of Azatioprina na doença inflamatória intestinal: fatores preditivos da resposta sustentada a longo prazo

GE Jornal Português de Gastrenterologia, 2014

Research paper thumbnail of Olmesartan-Induced Enteropathy: An Unusual Cause of Villous Atrophy

GE Portuguese Journal of Gastroenterology, 2016

We report a case of a 63-year-old-man presenting with chronic diarrhea and weight loss while on o... more We report a case of a 63-year-old-man presenting with chronic diarrhea and weight loss while on olmesartan treatment for hypertension. Investigation showed multiple nutritional deficiencies associated with diffuse intestinal villous atrophy. Serologies for celiac disease were negative and other causes of villous atrophy were excluded. Olmesartan as a precipitant agent was suspected and withdrawn. Clinical improvement occurred in days with no need for other therapeutic measures. Follow-up at three months showed clinical remission and almost complete recovery of intestinal atrophy. Olmesartan is an angiotensin receptor blocker commonly prescribed for the management of hypertension. Spruelike enteropathy associated with this drug is a recently described entity with few cases reported. It presents with chronic diarrhea and intestinal villous atrophy and should be included in its differential diagnosis. This case intends to alert clinicians for the possibility of this event in a patient on treatment with this drug.

Research paper thumbnail of Intraluminal Duodenal (“Windsock”) Diverticulum: A Rare Cause of Gastrointestinal Bleeding

GE Portuguese Journal of Gastroenterology, 2016

Research paper thumbnail of Risk factors for severity and recurrence of colonic diverticular bleeding

Revista Española de Enfermedades Digestivas, 2016

Research paper thumbnail of Azatioprina na doença inflamatória intestinal: fatores preditivos da resposta sustentada a longo prazo

GE Jornal Português de Gastrenterologia, 2014

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