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Papers by mensure kaya

The European Research Journal

Objectives: This study aimed to examine the effects of orally administered metoprolol on the freq... more Objectives: This study aimed to examine the effects of orally administered metoprolol on the frequency and severity of pain caused by rocuronium injection in patients who started to use and were currently using oral metoprolol for any reason such as ischemic heart disease, hypertension, and arrhythmias. Methods: Patients were evaluated in four groups. Group M: patients currently using metoprolol and who did not receive lidocaine before the application of rocuronium. Group ML: patients currently using metoprolol and who received lidocaine before rocuronium application. Group L: patients currently not using metoprolol and received lidocaine before rocuronium application. Group C: patients currently not using metoprolol and who did not receive lidocaine before rocuronium application. Following the induction of general anesthesia with thiopental sodium, a researcher blind to the groups observed the pain during rocuronium injection based on the following scale: (1) no reaction, (2) movem...

Lokman Hekim Health Sciences

Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has be... more Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become a standard procedure in diagnosing and staging lung cancer. Anesthesia management is one of the critical steps in the EBUS-TBNA procedures. We planned to evaluate anesthesia methods for EBUS-TBNA, which was applied for the first time in our hospital, in terms of duration of the procedure and complications. Methods: The records of patients who underwent EBUS-TBNA after ethics committee approval were reviewed retrospectively. We recorded demographic data of the patients, duration of the procedure, anesthesia methods, and complications. Results: A total of 50 patients were given anesthesia for the EBUS-TBNA. General anesthesia was performed in 5 patients and sedation in 45 patients.The duration of anesthesia was 62±17.8 min ingeneral anesthesiaand 50.2±13.1 min in sedated patients (p=0.113). Ketamine/propofol (ketofol) was used in 22 patients, and propofol/fentanyl was used in 23 patients for sedation. The amount of propofol was significantly higher in those using propofol/fentanyl than ketofol (propofol/fentanyl: 342.2±140 mg, ketofol: 166.5±49.9 mg; p=0.002).There was no significant difference in the frequency of postoperative complications. Discussion and Conclusion: The choice of anesthesia method for EBUS procedures should be adjusted according to factors associated with the operator, the patient, and the procedure itself. We think sedation can be used safely in EBUS procedures with good preliminary preparation, intraoperative management, and anesthesiologist-bronchoscopist compatibility.

The effect of orally administered metoprolol on the frequency and severity of rocuronium injection pain, 2023

ABSTRACT Objectives: This study aimed to examine the effects of orally administered metoprolol on... more ABSTRACT
Objectives: This study aimed to examine the effects of orally administered metoprolol on the frequency and severity of pain caused by rocuronium injection in patients who started to use and were currently using oral metoprolol for any reason such as ischemic heart disease, hypertension, and arrhythmias.
Methods: Patients were evaluated in four groups. Group M: patients currently using metoprolol and who did not receive lidocaine before the application of rocuronium. Group ML: patients currently using metoprolol and who received lidocaine before rocuronium application. Group L: patients currently not using metoprolol and received lidocaine before rocuronium application. Group C: patients currently not using metoprolol and who did not receive lidocaine before rocuronium application. Following the induction of general anesthesia with thiopental sodium, a researcher blind to the groups observed the pain during rocuronium injection based on the following scale: (1) no reaction, (2) movement only in the ankle, (3) movement or withdrawal only in the arm (shoulder and ankle), and (4) diffuse reaction (movement or withdrawal in more than one extremity, coughing and holding breath).
Results: Two hundred patients with 50 in each of four groups were included. The incidence of pain was statistically significantly lower in Group ML compared to Groups M and C (p = 0.001). The correlations between pain caused by rocuronium injection and duration of metoprolol usage and the time since the last dose were not statistically significant (for all, p > 0.05).
Conclusions: Oral metoprolol combined with lidocaine reduced pain and withdrawal reflex caused by rocuronium injection. No significant difference was observed between the last dose and the duration of metoprolol usage.

Objective: Postoperative sore throat (POST) is the most common discomfort after endotracheal intu... more Objective: Postoperative sore throat (POST) is the most common discomfort after endotracheal intubation. Damage to the tracheal mucosa caused by inappropriate endotracheal tube (ETT) cuff pressure has been shown as the major factor. Monitoring the ETT cuff pressure at a certain value reduces this damage. Benzydamine hydrochloride (BH) has proven to be effective on sore throat and studies have shown that it is also effective on POST. In this study, the efficacy of BH and ETT cuff pressure monitoring on POST was evaluated. Materials and methods: After ethics committee approval 210 patients in the ASA (American Society of Anesthesiologists) I-III risk group undergoing elective surgery were included in the study. Routine anesthesia monitoring, induction, and maintenance were provided. Patients were randomly divided into three groups. Thirty minutes before surgery, the posterior pharyngeal wall was sprayed with BH in group 1 and distilled water in groups 2 and 3. Intraoperatively, the first and second groups were monitored to keep the ETT cuff pressure between 22 and 26 cmH 2 O, while no intervention was performed in the third group. The incidence and severity of postoperative dysphagia, hoarseness, and POST were questioned. Results: There was no difference between demographic data, and gender was not associated with POST. There was a statistically significant difference between the first and second groups and the third group in terms of all three symptoms questioned (p<0.01). No difference was observed between the first and second groups. Side effect rates were similar. Smoking was not found to be associated with symptoms. Conclusion: The incidence and severity of POST, dysphagia, and hoarseness are reduced when the ETT cuff is inflated with a pressure of 22-26 cmH 2 O after intubation with a manometer and maintained at this pressure range throughout the operation. There was no beneficial effect of BH.

International Journal of Anesthesiology & Research, 2014

Patients were premedicated with midazolam 0.07 mg/kg im before surgery. In the operation room bef... more Patients were premedicated with midazolam 0.07 mg/kg im before surgery. In the operation room before performing spinal anesthesia, all of the patients received an infusion of 5 ml/kg NaCl % 0.9. Routine monitorization included ECG, noninvasive blood pressure, heart rate and pulsoxymeter and the basal measurements were noted. In group F, all femoral blocks were performed in the holding area or operating room before surgery. Under sterile conditions 55 mm block needle was inserted perpendicular to skin approximately 1 cm lateral to the femoral artery pulse that was marked

Amac: Total kalca protezi cerrahisinden sonra istirahatta ve hareketle artan agrinin kontrolu guc... more Amac: Total kalca protezi cerrahisinden sonra istirahatta ve hareketle artan agrinin kontrolu guc olabilmektedir. Bu calismada, hasta kontrollu lumbar pleksus analjezisinde, posterior yaklasimla psoas kompartman ve anterior yaklasimla uclu femoral sinir blokajinin analjezik etkinligi karsilastirildi. Yontem: Tek tarafli total kalca protezi planlanan ASA I-III grubunda 44 olgu calisma kapsamina alindi. Olgular psoas kompartman (grup P, n=22) ve uclu femoral sinir (grup F, n=22) blokaji icin rastgele iki gruba ayrildi. Genel anesteziden once, iki grupta da kateterler 0.5 mA veya daha az stimulus ile kuadriseps kasinda kontraksiyon goruldukten sonra yerlestirildi. Daha sonra tum olgulara adrenalinli 40 mi %0.25 bupivakain verilerek duyu blogu dagilimi kontrol edildi. Postoperatif 48 saat uygulanacak hasta kontrollu analjezi, %0.125 bupivakain ile bolus dozu 10 mi, kilitli kalma suresi 60 dk olacak sekilde planlandi. Postoperatif agri (istirahat ve fizyoterapi sirasinda), duyu blogu dag...

Propofol kısa etki süresi nedeniyle anestezi ve sedasyon için yaygın olarak kullanılan bir ilaçtı... more Propofol kısa etki süresi nedeniyle anestezi ve sedasyon için yaygın olarak kullanılan bir ilaçtır. Antikonvülzan olarak status epileptkus tedavisinde önerilmekle birlikte, epileptik hastalık ve kafa travması öyküsü olan hastalarda özellikle de düşük dozlarda kullanıldığında nöbet benzeri aktivite oluşturduğu bildirilmiştir. Sağ humerus proksimalinde basit kist nedeniyle biyopsi işlemi planlanan 27 yaşında kadın hastaya propofol 3 mg kg- 1 iv verildikten sonra bir dakika içinde hem alt hem üst ekstremitelerde tonik klonik tarzda kasılmalar gözlendi. Bu kasılmalar tiyopental uygulanarak kontrol altına alındı. Anestezi uygulamaları için çok sık kullanılan propofolün tamamen sağlıklı bireylerde ve yüksek dozda kullanıldığında da nöbet benzeri aktivite oluşturabileceğine dikkat çekmek ve tartışmak istedik.Propofol is a widely used drug because of short acting time for anesthesia and sedation. Although ıt has been suggested as a anticonvulsant in treatment of status epilepticus, it has b...

The Clinical Journal of Pain, 2021

Objectives: The primary objective of this prospective nonblinded randomized study was to investig... more Objectives: The primary objective of this prospective nonblinded randomized study was to investigate the effect of perioperative systemic lidocaine infusion on pain control after major gynecologic oncology surgery. Patient-reported outcomes, postoperative recovery parameters, and complications were secondary endpoints of the study. Materials and Methods: Seventy-five patients with American Society of Anesthesiologists I-III were divided into 3 groups based on perioperative analgesia methods—(1) opioid group: patient-controlled analgesia (PCA) with morphine; (2) lidocaine group: perioperative intravenous lidocaine infusion, plus PCA with morphine; and (3) the epidural group: PCA with bupivacaine. The Visual Analog Scale (VAS) was recorded postoperatively. In addition, nausea-vomiting, time to first oral intake, time to first ambulation, time to first flatus, and length of hospital stay were recorded. Results: VAS scores (rest) at 24 hours and VAS scores (cough) at 12 and 24 hours were significantly lower in the epidural group than in the opioid group (P<0.05). VAS scores were found to be similar between the lidocaine and epidural group. The nausea-vomiting incidence was lower in the lidocaine group than in the opioid group (P˂0.05). Compared with the other 2 groups, the first flatus time was shorter in the lidocaine group (P<0.05). Discussion: Perioperative lidocaine infusion is effective as epidural analgesia, which is often advocated as the gold-standard analgesic technique for abdominal surgery and is superior to the others in terms of time to first flatus and the incidence of nausea-vomiting.

Acta Oncologica Turcica, 2020

Literatürde hemipelvektomi anestezi yönetimi hakkında karşılaşılan çok fazla bilgi 5 bulunmamakta... more Literatürde hemipelvektomi anestezi yönetimi hakkında karşılaşılan çok fazla bilgi 5 bulunmamaktadır. Bu çalışma ile nadiren yapılan hemipelvektomi sonrası allogreftle rekonstrüksiyon anestezi yönetimine dikkat çekmek istiyoruz. YÖNTEM ve GEREÇLER: Aralık 2010-Şubat 2014 tarihleri arasında internal hemipelvektomi ve allogreftle rekonstrüksiyon cerrahisi yapılan hastalarda dosya incelemesi retrospektif olarak yapıldı. Yaş, cinsiyet, ASA, ek hastalık, uygulanan anestezi yöntemi, preoperatif ve postoperatif hemoglobin değeri, intraoperatif kanama miktarı, intraoperatif verilen mayi ve kan transfüzyon miktarı, operasyon süresi, yoğun bakım ve hastanede kalış süreleri, mortalite-morbidite oranları değerlendirildi.

Paracetamol is combined with opioids or used alone for management of post-operative pain. In this... more Paracetamol is combined with opioids or used alone for management of post-operative pain. In this study, we investigated the effect of intravenous (IV) paracetamol on morphine consumption used for post-operative pain after modified radical mastectomy. SixtyASA l-lll patients scheduled for modified radical mastectomy under general anesthesia were randomly allocated into two groups by using closed envelope system (Group P; n= 30, Group S; n= 30). Anesthesia was induced with fentanil 1-2/vg/kg, cisatracurium 0.15 mg/kg and propofol 2-2.5 mg/kg, maintained with sevoflurane 1-2%, N20 66%/Oz. Group P received paracetamol 1 g, infused in 15 minutes one hour before the end of surgery and at six hours intervals in post-operative 24 hours. Şaline infusion was given to Group S at the same time. Ali patients were connected to a patient controlled analgesia device adjusted to deliver morphine 5 mg as loading, 1 mg bolus and five minutes lock-out time. A bolus of morphine 5 mg was administered if...

Background: Continuous spinal anaesthesia has been used as a possibly safer technique than genera... more Background: Continuous spinal anaesthesia has been used as a possibly safer technique than general anesthesia alone, in high-risk patients with a more predictable effect and lesser hemodynamic and respiratory repercussions. Aim: To evaluate the consequences of continuous spinal anaesthesia and analgesia, in 52 high-risk patients undergoing major abdominal surgery. Settings and Design: Operating room and postanaesthesia care unit of an oncology hospital; a prospective study. Materials and Methods: After inserting the 22 gauge spinal catheter, plain 0.5% Bupivacaine 7.5 mg was administered through the catheter. Additional doses of Bupivacaine 2.5 mg were given, until a sensory T 4 level and total dose was noted. The postoperative analgesia involved a continuous intrathecal infusion of Sufentanil 1 mg h -1 with Bupivacaine 1 mg h -1 . Pain scores and side effects were assessed at 1, 2, 4, 6, 12, 18 and 24 h after the surgery. Results: The dose of Bupivacaine required to achieve the sen...

Turkiye Klinikleri Journal of Anesthesiology Reanimation, 2008

Objective: The effects of adding single dose sciatic nerve block to continuous femoral block was ... more Objective: The effects of adding single dose sciatic nerve block to continuous femoral block was compared with continuous femoral block for postoperative analgesia and knee rehabilitation for total knee arthroplasty. Material and Methods: Forty ASA I-III patients scheduled for unilateral total knee arthroplasty were allocated into the study. They were randomly assigned into one of two groups: Group F: Continuous femoral analgesia, Group FS: Continuous femoral analgesia + single dose sciatic nerve block. Femoral catheters were placed in both groups before spinal anesthesia. The patients in Group FS received sciatic nerve block after femoral catheterisation. The patient controlled analgesia device which was planned to continue for postoperative 48 hr and deliver %0.125 bupivacaine 0.05 ml/kg bolus, 0.1 ml/kg/hr infusion with 30 min lock out interval was connected to the femoral catheters. The pain scores at rest and during physiotherapy at postoperative 6, 12, 24 and 48 hr, additional...

Medicine Science | International Medical Journal, 2019

Despite being a routine practice, preoperative fasting was shown not to decrease the amount and a... more Despite being a routine practice, preoperative fasting was shown not to decrease the amount and acidity of gastric content. In fact, excessive hunger is associated with adverse outcomes and delayed recovery. Research demonstrating such efficacy of preoperative oral carbohydrates still remains controversial. In this study, we aimed to evaluate the effects of preoperative oral carbohydrate solution (OCS) intake on preoperative and postoperative anxiety levels of surgical patients. Sixty patients who would undergo surgical intervention with ASA I score were included to the study. Patients were randomized to receive either 400 ml OCS (Group I, n=30) or 400 ml water (Group II, n=30) each at the last night and two hours before surgery. Three groups of anxiety tests, including the State-Trait Anxiety Inventory (STAI), the Amsterdam Preoperative Anxiety and Information Scale (APAIS), and Visual Analog Scale for Anxiety (VAS-A), were performed at the night and two hours before and six hours after the operation. At t1, the mean VAS-A was significantly lower in Group I (43.2±20.9) compared to that in Group II (59.7±24.1; p=0.01). STAI at t1 was also significantly lower in Group I than that in Group II (44.7±12.6 and 51.9±13.0, respectively; p=0.032). The scores in the other time-points (t0 and t2) were found as similar. APAIS scores did not differ between the groups. Preoperative OSC intake seems to have a tendency of reducing anxiety in operated cancer patients.