mohamad abou chakra - Academia.edu (original) (raw)
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University of California, San Francisco
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
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Papers by mohamad abou chakra
Intractable & Rare Diseases Research, 2020
Peyronie's disease (PD) is a connective tissue disorder of the penis characterized by fibrosis an... more Peyronie's disease (PD) is a connective tissue disorder of the penis characterized by fibrosis and plaque formation within the tunica albuginea. PD is characterized by painful penile curvature that impairs sexual intercourse. Stem cell therapy is one of the recent non-invasive treatment options for patients with PD and it has promising results. Stem cells are undifferentiated cells that are capable of self-renewal and differentiation, promoting the repair of tissues via their immunomodulatory and anti-inflammatory action. Adipose-derived stem cells (ADSC) are used most widely due to their abundant tissue source and ease of isolation. Multiple studies have indicated the efficacy of stem cell therapy as a potential treatment for fibrotic diseases. Clearly, ADSCs may represent a way to treat and prevent PD in both rat and human models. Further clinical studies are needed to confirm the efficacy of stem cell therapy for PD in humans.
High-rise buildings are growing rapidly in number around the world. They are becoming important l... more High-rise buildings are growing rapidly in number around the world. They are becoming important landmarks that mark out certain geographical areas. The fires of high-rise building have many characters not found in traditional low-rise buildings, like the variety of blazing factors, ways of fire spreading, and difficulty of evacuation. Hence, the protection features of conventional fire methods are not sufficient in designing towers. The paper, at first, summarizes the characteristics of high-rise buildings and fires, the unique features of Tall Buildings and the special life safety requirements for the high-rise buildings. Consequently, the topic of fire and life safety codes implementation during the design and construction phases should be brought to the forefront into the building design process, in order to improve the skills of architectural engineers concerning the integration of safety and fire protection methods. Then, case studies have been selected from PETRONAS tower Mala...
Intractable & Rare Diseases Research, 2020
Peyronie's disease (PD) is a connective tissue disorder of the penis characterized by fibrosis an... more Peyronie's disease (PD) is a connective tissue disorder of the penis characterized by fibrosis and plaque formation within the tunica albuginea. PD is characterized by painful penile curvature that impairs sexual intercourse. Stem cell therapy is one of the recent non-invasive treatment options for patients with PD and it has promising results. Stem cells are undifferentiated cells that are capable of self-renewal and differentiation, promoting the repair of tissues via their immunomodulatory and anti-inflammatory action. Adipose-derived stem cells (ADSC) are used most widely due to their abundant tissue source and ease of isolation. Multiple studies have indicated the efficacy of stem cell therapy as a potential treatment for fibrotic diseases. Clearly, ADSCs may represent a way to treat and prevent PD in both rat and human models. Further clinical studies are needed to confirm the efficacy of stem cell therapy for PD in humans.
High-rise buildings are growing rapidly in number around the world. They are becoming important l... more High-rise buildings are growing rapidly in number around the world. They are becoming important landmarks that mark out certain geographical areas. The fires of high-rise building have many characters not found in traditional low-rise buildings, like the variety of blazing factors, ways of fire spreading, and difficulty of evacuation. Hence, the protection features of conventional fire methods are not sufficient in designing towers. The paper, at first, summarizes the characteristics of high-rise buildings and fires, the unique features of Tall Buildings and the special life safety requirements for the high-rise buildings. Consequently, the topic of fire and life safety codes implementation during the design and construction phases should be brought to the forefront into the building design process, in order to improve the skills of architectural engineers concerning the integration of safety and fire protection methods. Then, case studies have been selected from PETRONAS tower Mala...