mohammed algaradah - Academia.edu (original) (raw)

Papers by mohammed algaradah

Journal of Alloys and Compounds

American Journal of Analytical Chemistry, 2021

In recent days, the applications of silica-based nanoparticles have gained much attention. The pr... more In recent days, the applications of silica-based nanoparticles have gained much attention. The preparation of mesoporous silicas is usually achieved via the modified Stöber method, the reaction attained by the hydrolysis and condensation of silica precursors present within a medium containing template, solvent, deionized water (DI-W) and base. Therefore, the current study aimed to prepare and characterize mesoporous silicas by using tetramethoxysilane (TMOS) as silica precursor and ethylene glycol (Et-G) as solvent. The study was based on the template dodecyltrimethylammonium bromide (C 12 TMABr) and sodium hydroxide used as an alkaline agent. Mesoporous silicas were prepared in various batches based on TMOS molar concentration, ionized water, NaOH, and other solvents. The characterization of mesoporous silicas was achieved based on their specific surface area, pore size distribution and morphology using different instruments: Brunauer, Emmett & Teller (BET), scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), and thermalgravimetric analysis (TGA). The study revealed that shape, average particle sizes "35 to 550 nm", average pore radius "1.62-4.5 nm" and surface area "350-1204 m 2 •g −1 " of obtained mesoporous silica particles were altered based on precursor concentration and other factors. Therefore, it is important to get the most suitable concentration of all chemicals in the preparation of mesoporous silicas to control the particle characteristics to use them upon their further applications. This is the baseline study that provides details regarding prepared silica particles with controlled characteristics, and more studies related to its applications are still in process. How to cite this paper: Algaradah, M.M.

An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Egyptian Journal of Chemistry

ACS Applied Materials & Interfaces

Journal of the American Chemical Society, Jan 27, 2016

Porous metal-organic frameworks (MOFs) have been studied in the context of a wide variety of appl... more Porous metal-organic frameworks (MOFs) have been studied in the context of a wide variety of applications, particularly in relation to molecular storage and separation sciences. Recently, we reported a green, renewable framework material composed of γ-cyclodextrin (γ-CD) and alkali metal salts - namely CD-MOF. This porous material has been shown to facilitate the separation of mixtures of alkylaromatic compounds, including the BTEX (benzene, toluene ethylbenzene and the regioisomers of xylene) mixture, into their pure components, in both the liquid and gas phases, in an energy-efficient manner which could have implications for the petrochemical industry. Here, we report the ability of CD-MOF to separate a wide variety of mixtures, including ethylbenzene from styrene, haloaromatics, terpinenes, pinenes and other chiral compounds. CD-MOF retains saturated compounds to a greater extent than their unsaturated analogs. Also, the location of a double bond within a molecule influences its ...

Materials Research Bulletin, 2016

Barium and bismuth titanate thin films and well-ordered inverse opal films are produced by dip co... more Barium and bismuth titanate thin films and well-ordered inverse opal films are produced by dip coating from sols containing titanium alkoxides with acetic acid, acetylacetone, methoxyethanol and water. The inverse opal preparations used crosslinked polystyrene opal templates. Heat treatment in air produced tetragonal BaTiO 3 or mixtures of the hexagonal and tetragonal phases, or phase pure Bi 2 Ti 2 O 7. Good quality films were obtained with a thickness of 5 mm from a single dipping, and the thickness could be increased by dipping multiple times. Inverse opals were well ordered and exhibited opalescence and photonic stop band effects. 2015 Published by Elsevier Ltd.

Phosphorus Sulfur and Silicon and the Related Elements

... DOI: 10.1080/10426500490262513 HZ Alkhathlan a , MA Al-Jaradah a , KA Al-Farhan a & A... more ... DOI: 10.1080/10426500490262513 HZ Alkhathlan a , MA Al-Jaradah a , KA Al-Farhan a & AA Mousa a pages 373-388. Available online: 11 Aug 2010. ...

Advanced Materials, 2015

Shape-persistent molecular triangles comprising three electron-deficient, electronically coupled ... more Shape-persistent molecular triangles comprising three electron-deficient, electronically coupled naphthalenediimide units provide a unique scaffold for stable electrochemical redox reactions and fast ion diffusion in the solid state. On page 2907, J. F. Stoddart and co-workers demonstrate the high rate performance of these lightweight active materials for advancing the state of rechargeable organic lithium-ion batteries. Image credits: Aleksandr Bosoy and Dr. Paul R. McGonigal.

Journal of the American Chemical Society, Jan 25, 2015

Metal-organic frameworks (MOFs) are known to facilitate energy-efficient separations of important... more Metal-organic frameworks (MOFs) are known to facilitate energy-efficient separations of important industrial chemical feedstocks. Here, we report how a class of green MOFs - namely CD-MOFs - exhibits high shape-selectivity towards aromatic hydrocarbons. CD-MOFs, which consist of an extended porous network of γ-cyclodextrins (γ-CDs) and alkali metal cations, can separate a wide range of benzenoid compounds as a result of their relative orientation and packing within the transverse channels, formed from linking (γ-CD)6 body-centered cuboids in three dimensions. Adsorption isotherms and liquid-phase chromatographic measurements indicate a retention order of ortho- > meta- > para-xylene. The persistence of this regioselectivity is also observed during the liquid-phase chromatography of the ethyltoluene and cymene regioisomers. In addition, molecular shape-sorting within CD-MOFs facilitates the separation of the industrially relevant BTEX (Benzene, Toluene, Ethylbenzene and the Xyl...

Nanoscale, Jan 30, 2015

Gating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) ... more Gating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) has been achieved. This hybrid nanocarrier releases doxorubicin (DOX) under acidic conditions or in the presence of porcine liver esterase. The DOX loaded poly(β-amino ester)-capped MSNs reduce cell viability when tested on MDA-MB-231 human breast cancer cells.

Advanced materials (Deerfield Beach, Fla.), Jan 27, 2015

Molecular triangles containing naphthalenediimide redox-active units have been employed as promis... more Molecular triangles containing naphthalenediimide redox-active units have been employed as promising active materials for organic lithium-ion batteries. In addition to exceptional low-rate performance, a capacity of 71.1 mAh g(-1) is maintained at 10 C after 300 cycles. The performance of these organic compounds exists in contrast to a control naphthalenediimide monomer, which lacks the same shape-persistent structure.

ACS Nano, 2015

Polyaromatic compounds are well-known to intercalate DNA. Numerous anticancer chemotherapeutics h... more Polyaromatic compounds are well-known to intercalate DNA. Numerous anticancer chemotherapeutics have been developed upon the basis of this recognition motif. The compounds have been designed such that they interfere with the role of the topoisomerases, which control the topology of DNA during the cell-division cycle. Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report in vitro cell studies for a library of these dications. These investigations reveal that a number of 2,9-diazaperopyrenium dications show similar activities as doxorubicin toward a variety of cancer cell lines. Additionally, we report the solid-state structures of these dications, and we relate their tendency to aggregate in solution to their toxicity profiles. The addition of bulky substituents to these polyaromatic dications decreases their tendency to aggregate in solution. The derivative substituted with 2,6-diisopropylphenyl groups proved to be the most cytotoxic against the majority of the cell lines tested. In the solid state, the 2,6-diisopropylphenyl-functionalized derivative does not undergo π 3 3 3 π stacking, while in aqueous solution, dynamic light scattering reveals that this derivative forms very small (50À100 nm) aggregates, in contrast with the larger ones formed by dications with less bulky substituents. Alteration of the aromaticitiy in the terminal heterocycles of selected dications reveals a drastic change in the toxicity of these polyaromatic species toward specific cell lines.

... A dual functionality diol/C18-nanoscavenger was used to collect four estrogenic compounds, po... more ... A dual functionality diol/C18-nanoscavenger was used to collect four estrogenic compounds, polynuclear aromatic hydrocarbons and tributyltin from water. The recovery of extracted analytes by nanoscavengers exhibited good results. Item Type: Thesis (Doctoral). ...

Organic Letters, 2015

A versatile surface-functionalization strategy applicable to mesoporous silica nanoparticles, whi... more A versatile surface-functionalization strategy applicable to mesoporous silica nanoparticles, which could potentially serve as drug delivery vehicles, is described that makes use of alkoxyamine tethers on the surface of the nanoparticles. A wide variety of carbonyl compounds can be attached readily to these tethers under the mild conditions of oxime ether formation, simply by incubating the chemically modified mesoporous silica nanoparticles with aldehydes or ketones in water.