mohammed mahmoud - Academia.edu (original) (raw)
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Vardhman mahavir medical college & safdarjung hospital, new delhi
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Papers by mohammed mahmoud
Journal of the Egyptian National Cancer Institute, Jan 24, 2017
Proper surgery with adequate safety margin and adjuvant radiotherapy is the main line of treatmen... more Proper surgery with adequate safety margin and adjuvant radiotherapy is the main line of treatment of extremity and trunk soft tissue sarcoma (STS). In spite of improved management, the long term follow up is still not satisfactory. To evaluate long term outcome of STS of extremities and trunk regarding adequacy of resection, recurrence and survival. This prospective study included 25 patients with STS involving extremity and trunk. All patients were treated with wide radical excision and had adjuvant irradiation and followed up for a median of 26months. The mean age was 40.0±15.3years. They were 16 males and 9 females. Eight patients (32%) had positive or close surgical margins. The median overall survival (OS) was 26.5months. In univariate analysis, lower limb tumors, stage III and grade 3 were significantly associated with worse overall survival (OS) (p=0.007, 0.02, and 0.020, respectively) and disease free survival (DFS) (p=0.005, 0.001, and 0.001, respectively). On multivariate...
Journal of the Egyptian National Cancer Institute, Jan 24, 2017
Proper surgery with adequate safety margin and adjuvant radiotherapy is the main line of treatmen... more Proper surgery with adequate safety margin and adjuvant radiotherapy is the main line of treatment of extremity and trunk soft tissue sarcoma (STS). In spite of improved management, the long term follow up is still not satisfactory. To evaluate long term outcome of STS of extremities and trunk regarding adequacy of resection, recurrence and survival. This prospective study included 25 patients with STS involving extremity and trunk. All patients were treated with wide radical excision and had adjuvant irradiation and followed up for a median of 26months. The mean age was 40.0±15.3years. They were 16 males and 9 females. Eight patients (32%) had positive or close surgical margins. The median overall survival (OS) was 26.5months. In univariate analysis, lower limb tumors, stage III and grade 3 were significantly associated with worse overall survival (OS) (p=0.007, 0.02, and 0.020, respectively) and disease free survival (DFS) (p=0.005, 0.001, and 0.001, respectively). On multivariate...