mr mohamed eid - Academia.edu (original) (raw)

Papers by mr mohamed eid

This is a revision of (he past seven years experience in activation calculations for dismantling.... more This is a revision of (he past seven years experience in activation calculations for dismantling. It aims at evaluating lhc experience and at making better understanding to help in decision making during the following phases. Five gas cooled reactors are shutdown and arc waiting for the EDF (Electricite Dc France) dismantling decision. The sixth (BUGYl) will be shutdown by 1994 and will be wailing a dismantling decision as well.

Matrix Science Pharma, 2020

Vitamin D is a group of fat-soluble vitamins responsible for intestinal absorption of calcium and... more Vitamin D is a group of fat-soluble vitamins responsible for intestinal absorption of calcium and phosphate. Vitamin D deficiency (VDD) has reached an epidemic in both developed and developing countries. Literature review showed that population knowledge, attitude, and practice concerning Vitamin D were poor. Prescribing doctors and pharmacist are an important source of health information. Hence, their knowledge and practices about Vitamin D is essential for their roles and needs to be highlighted. Objectives: The aim of this study is to assess knowledge, attitude, and practice regarding Vitamin D among community pharmacists and prescribing doctors in Khartoum City, Sudan, 2020. Materials and Methods: An observational cross-sectional study was carried out from February to April 2020 among 94 community pharmacists and 106 prescribing doctors using a validated electronic delivery self-administered questionnaire in Khartoum locality. Results: About 32.7% and 41.9% from prescribing doctors and pharmacists had poor general knowledge, respectively, regarding VDD, while the significant trend was found regarding the level of knowledge and year of experience (P = 0.022) of all health professionals (pharmacists and doctors). About 39.3% and 44.1% from prescribing doctors and pharmacists, respectively, had poor nutrition knowledge score toward Vitamin D with a significant trend regarding nutrition knowledge score and different gender groups (P = 0.02) of all health professionals in the study. About 49.5% and 47.5% from prescribing doctors and pharmacists, respectively, had poor attitude scores toward Vitamin D with a significant trend regarding nutrition knowledge score and attitude score (P = 0.037) of all health professionals. Conclusion and Recommendations: This survey identified a gap in the general knowledge, nutritional knowledge, and attitude among health-care professionals (prescribing doctors and pharmacists).

Egyptian Journal of Radiology and Nuclear Medicine, 2020

Background Inverted papilloma (IP) is an uncommon sino-nasal neoplasm with potentially distinctiv... more Background Inverted papilloma (IP) is an uncommon sino-nasal neoplasm with potentially distinctive MRI and CT features. The MR “striated” imaging pattern has been reported as a valuable MR imaging feature of IP. The purpose of this study was to validate the usefulness of this sign using detailed criteria of the sign itself. Results All imaging findings were described for 16 patients in descriptive pattern. The nasal involvement showed highest prevalence followed by the maxillary sinus. The bony changes include remodeling and defects (n = 6), remodeling only (n = 4), and None (n = 6). Changes were severe 1/10, moderate in 3/10, and mild 5/10. Focal hyperostosis was seen in six. A striated pattern was “diffuse” in all 16 (100%) of the IPs; it followed a certain direction in all 16 patients: divergent (n = 6), convoluted (n = 2), and parallel (n = 8). Divergent growth from focal hyperostosis was seen (n = 4). Visibility of the sign was superior in T2 images (n = 11), superior in enhanc...

Journal of Molecular Liquids, 2019

Mitigation the activity of α-amylase and α-glucosidase is scientifically spotlighted to potential... more Mitigation the activity of α-amylase and α-glucosidase is scientifically spotlighted to potentially decrease the glucose absorption and scavenge category 2-diabetes mellitus in the humans. For the first time, we elucidated the underlying mechanism of the inhibitory activity of 3 structurally different phytosterols (PS) on α-amylase and α-glucosidase using multispectral and molecular docking approaches. It was found that stigmasterol, βsitosterol, and γ-oryzanol integratedly (competitive and uncompetitive) inhibited both of α-amylase and αglucosidase. The spectrofluorometric results demonstrated that a static interaction of PS with both enzymes happened, leading to the changes in Z-average size, UV-vis spectrum, and secondary structures of these amylolytic enzymes. Moreover, each PS noncovalently interacted with several residues close to the active sites of both enzymes via H-bonding and π-π forces, causing indirectly inhibition to their catalytic activity. However, γoryzanol was highly inhibited both enzymes than the other PS since its structure in which contained ferulic acid esterified with sterol, which could be used as nutraceutical ingredients.

Stereotactic and functional neurosurgery, Jan 18, 2018

The optimum target in surgery for Parkinson's disease (PD) is still controversial, especially... more The optimum target in surgery for Parkinson's disease (PD) is still controversial, especially in patients with tremor-dominant PD. We aim to compare results in tremor-dominant patients undergoing pallidotomy vs. those undergoing simultaneous posteroventral pallidotomy (PVP) and ventral intermediate nucleus (VIM) thalamotomy. Twenty-four patients with tremor-dominant PD were included in this study. Twelve patients received unilateral PVP contralateral to the most affected side. The other 12 patients received simultaneous unilateral PVP and VIM thalamotomy contralateral to the most affected side. Assessment of results in both groups was achieved using both UPDRS "off" motor scores and UPDRS rest tremor subscores. The mean UPDRS off motor score improved in the pallidotomy group from 61.3 preoperatively to 36.8 at 12 months. In the combined group, it improved from 59.6 to 35.2 at 12 months, with no statistically significant difference between both groups. On the other hand...

Studies in Systems, Decision and Control, 2016

The ultimate target of Modelling and Simulation (M&S) activities in the field of CIP is to provid... more The ultimate target of Modelling and Simulation (M&S) activities in the field of CIP is to provide Models, Methodologies and tools to help in the analysis of different crisis' scenarios and, subsequently, in crisis management decision making. A CIs' disruptions scenario is simply a sequence of random events following a well-defined chronological order. Generally, each identified scenario produces a set of consequences which is a function of: the initiating event, the concerned CIs and the geo-organizational context of the disrupted CIs. Formal sciences represent the reality of our surrounding world. But formal sciences are imperfect and what we call "reality" is the projection of the inaccessible "Reality" on our world. This projection is the only reality we are talking about in formal sciences. Subsequently, formal sciences construct objects in which small parts of the sensible reality are grasped and formalized. These objects can be called "models". We are limiting our interest here to formal sciences and engineering activities that cover both conceptual and phenomenological modelling processes. Models are first validated before being admitted in the construction of a global model of the sensible reality. Regarding our focus on crisis scenarios modelling, simulation and analysis (MS&A), engineers' ambition is to simulate not only independent isolated phenomenon but also interacting multi-physic multi-scale phenomenon. M. Eid (&) Commissariat à l'énergie atomique et aux énergies alternatives,

European Archives of Oto-Rhino-Laryngology, 2016

56 patients affected by T2 glottic carcinoma were treated in two institutes using transoral laser... more 56 patients affected by T2 glottic carcinoma were treated in two institutes using transoral laser microsurgery (TLM) in 40 cases and vertical hemilaryngectomy in 16 cases between September 2012 and September 2015. In the TLM group, different subtypes of type V cordectomy were used according to the extent of tumor. In the vertical hemilaryngectomy group, classical operation was used in most of the cases and the resection was extended in few cases. Analysis of post-operative swallowing function was done using videofluoroscopy (VFS), functional endoscopic evaluation of swallowing, and subjectively using MD Anderson dysphagia inventory. Objective evaluation of swallowing has been made by obtaining different measures from VFS (pharyngeal transit time, pharyngeal constriction ratio, and hyoid displacement for example). Analysis also included the need and duration of tracheostomy and nasogastric tube, ICU admission, and hospitalization time. Statistical analysis was performed with the Mann-Whitney U and Pearson Chi-square tests. Comparison of incidence of aspiration and swallowing outcome showed significantly better results in the laser group than in the vertical group (p < 0.001). The duration of ICU, tracheostomy, nasogastric tube, and hospital stay was also significantly shorter in the laser group (p < 0.001). This study shows that TLM had significantly better overall postoperative outcome than vertical hemilaryngectomy. It was associated with significantly shorter hospital stay and less need for tracheostomy, nasogastric tube, and ICU admission). Measures obtained from VFS are useful for detection and follow-up of postoperative aspiration, because it is a definitive technique for anatomical and physiological study of swallowing.

The Egyptian Journal of Radiology and Nuclear Medicine, 2014

Background: Subtraction imaging is a technique whereby an unenhanced T1-weighted sequence is digi... more Background: Subtraction imaging is a technique whereby an unenhanced T1-weighted sequence is digitally subtracted from the identical sequence performed after gadolinium administration. Aim of the work: This study will highlight the role of subtraction imaging for non-vascular MRI applications. Subjects and methods: The study included 40 patients presenting with lesions in different parts of the body, that are initially hyperintense on T1W sequences. We used post-processing software (Osirix) to digitally subtract the pre-enhancement from the post enhancement sequences. Results: Based on subtraction imaging findings 5 patients were diagnosed with intraocular melanomas, two patients were diagnosed with hemorrhagic cysts in the masseter muscle , two patients were diagnosed with hemorrhagic cysts in the parotid gland, two patients were diagnosed with dysplastic hepatic nodules, 5 patients were diagnosed with post-ablation necrosis following hepatocellular carcinoma (HCC) treatment, two patients showed recurrent HCC after chemoembolisation, 3 patients showed chemoembolised HCC without recurrence, 4 patients showed intraluminal gall bladder sludge, 4 patients showed hemorrhagic renal cysts, one patient showed solid papillary neoplasm of the pancreas, 6 patients showed chocolate ovarian cysts, two patient showed ovarian cystadenoma and two patients showed ovarian cystadenocarcinoma. Conclusion: Subtraction MRI is very helpful tool in non-vascular MRI applications.

The Egyptian Journal of Radiology and Nuclear Medicine, 2014

Introduction: Differentiating a benign from a malignant adnexal mass would provide a basis for op... more Introduction: Differentiating a benign from a malignant adnexal mass would provide a basis for optimal preoperative planning and may also reduce the number of unnecessary laparotomies patients undergoing treatment for benign disease. MRI provides additional information on the composition of soft-tissue masses using differences in MR relaxation properties seen in various types of tissue. More recently developed MRI sequences, like diffusion weighted, susceptibility weighted, and dynamic contrast enhancement sequences provided additional capacities for adnexal lesion tissue characterization. Aim of the work: The aim of this work was to study the role of MRI including the novel sequences, namely dynamic contrast enhanced MRI (DCE-MRI), diffusion weighted images (DWI) and susceptibility weighted images (SWI) in the characterization of ovarian masses. Patients and methods: This study included 25 patients having indeterminate adnexal masses at ultrasound. They were subjected to pelvic MRI, including T1, T2, T1 fat sat sequences, as well as the DWI, SWI, and DCE sequences. Final diagnosis was reached through histopathological data, or therapeutic response. Results: All endometriomas showed blooming on SWI. All malignant lesions showed restricted diffusion and type III DCE curves. Conclusion: MRI, especially the more recent sequences (DWI, SWI and DCE) allows accurate characterization of ovarian lesions.

The Egyptian Journal of Radiology and Nuclear Medicine, 2012

Living donor liver transplantation is increasingly being used to help compensate for the increasi... more Living donor liver transplantation is increasingly being used to help compensate for the increasing shortage of cadaveric liver grafts. However, the extreme variability of the hepatic vascular and biliary systems can impede this surgical procedure. The aim of the study is to demonstrate the role of MR cholangiopancreatography (MRCP) in the evaluation of anatomical biliary variants in potential living donors for liver transplantation. Methods: The study included 20 liver donors in pre-operative assessment before liver transplantation. MR cholangiopancreatography (MRCP) was performed for all donors. Results: The study included 20 donors (16 men and 4 women) ranging in age from 29 to 52 years. 16 (80%) donors demonstrate normal biliary branching anatomy. One donor has trifurcation biliary branching pattern (5%). Two donors have their right posterior ducts draining into the left hepatic duct (10%). One donor has low insertion of the right posterior duct into the main duct (5%). Conclusion: MR cholangiopancreatography (MRCP) provides important information in evaluation of potential living donors for liver transplantation.

The Egyptian Journal of Radiology and Nuclear Medicine, 2012

Background: GISTs are considered the commonest mesenchymal neoplasms of the GIT originating from ... more Background: GISTs are considered the commonest mesenchymal neoplasms of the GIT originating from the gastrointestinal tract, mesentery, omentum, or retroperitoneum. They arise within the gut musculosa having exophytic growth pattern. They characteristically have hemorrhage, necrosis, or cyst formation that appears as focal areas of low attenuation on computed tomographic images. With multidetector CT (MDCT) capabilities, the exact origin of the GIST can be easily confirmed to differentiate it from other mesenchymal origin tumors. Materials and methods: Retrospective search for GIST cases in the digital archives of our institute, during a 15 months duration (April 2010 to July 2011). Workstation reviewing of their imaging features. Results: This study included 24 pathologically proved GISTs (12 gastric, 8 small intestinal, two colonic, one mesenteric and one anorectal) demonstrating the radiologic features of GISTs depending on tumor size and organ of origin. Conclusion: MDCT with its multiplanar capabilities and isotropic z-axis resolution allows the radiologist to examine the detailed relation of the mass to the surrounding bowel wall, vessels and other structures. It also helps to map the vascular pedicle in cases of hypervascular GIST's, which may be crucial for trans-catheter embolization in cases presenting with acute gastrointestinal bleeding.

Strategies in Trauma and Limb Reconstruction, 2010

Sixteen patients underwent minimally invasive subtalar arthrodesis through a mini-invasive approa... more Sixteen patients underwent minimally invasive subtalar arthrodesis through a mini-invasive approach with posterior iliac graft between 2004 and 2006. No hardware was used to transfix the arthrodesis and partial weight bearing was allowed immediately. The primary indication for surgery was the squeal of fracture os calcis in terms of subtalar joint arthritis, loss of heel height, malalignment of the hindfoot, and pain with weight bearing. There were 12 male and 4 female patients with a mean age of 30 (range 17-52). Patients were followed up for a period of 40.8 months (range 36-48 months). The mean interval from injury to fusion was 2 (?0.6) years ranging from 6 months to 6 years post fracture. The average clinical rating scale based on the American Orthopaedic Foot and Ankle Society (AOFAS) improved from 36 preoperatively to 78 at the latest follow-up (P \ 0.05). Union rate was 94%. Radiographic evaluation revealed a mean increase in calcaneal inclination of 6.25 ? 8.3°(P \ 0.07) and a mean increase in the lateral talocalcaneal angle of 7.42 ? 10.2°(P \ 0.08). Complications were graft nonunion in 1 patient and transient tendoachilles tendinitis in another. This technique can be used to decrease the morbidity associated with the late complications of os calcis fractures by aligning the hindfoot, restoring the heel height and correcting calcaneal and talar inclination. It offers the advantage of early weight bearing while avoiding hardware complications.

European Journal of Orthopaedic Surgery & Traumatology, 2014

Purpose Patients with generalized hyperlaxity with frank recurrent anterior shoulder dislocation ... more Purpose Patients with generalized hyperlaxity with frank recurrent anterior shoulder dislocation had high failure rate after conservative and soft tissue stabilization procedures. Our hypothesis is that a Latarjet procedure can provide an alternative successful approach to manage such cases. Methods This prospective study was conducted on 13 patients with multiple recurrences of anterior shoulder dislocation. The mean age was 24.4 years. They all had generalized ligamentous laxity according to Beighton's scale with a mean score of six points. Hill-Sach's lesion was \20 % of the head diameter with no glenoid defect; otherwise, the case was not included in the study. The modification of Burkhart and de Beer ''congruent-arc Latarjet procedure'' was performed for all patients through a limited deltopectoral approach. Results Re-dislocation occurred in one case only over the follow-up period. It occurred once after a violent act. Their preoperative mean Rowe score was 47.5 points preoperatively and increased to 91.07 postoperatively. This improvement was statistically highly significant (p value\0.001). The mean range of postoperative external rotation was 69.29°. Conclusion Latarjet procedure provides a higher success rate in such patients with multiple recurrences regarding both shoulder stability and function compared to capsulolabral repair procedures. Level of evidence IV.

Alexandria Journal of Medicine, 2013

The study aims not only to determine the value of preoperative MRI of perianal fistula but also t... more The study aims not only to determine the value of preoperative MRI of perianal fistula but also to detect MRI fallacious results, if any. Also, it aims to suggest how we can limit such false positive MRI results that may lead to unnecessary surgery. Patients and methods: This was a prospective comparative study, included 100 patients. Fifty of them (group A) were operated following the guidance of preoperative MRI, while the other 50 patients (group B) directly operated without MRI. The study protocol was approved by the ethics committee in Al-Mana General Hospital.

International Journal of Pediatric Otorhinolaryngology, 2012

Pediatric traumatic cerebrospinal fluid (CSF) leak is a challenging problem in diagnosis and mana... more Pediatric traumatic cerebrospinal fluid (CSF) leak is a challenging problem in diagnosis and management. Posttraumatic leaks frequently present by intermittent rhinorrhea or by recurrent attacks of meningitis, which can be the only presenting symptom. The objective of this study is to present our experience in management of pediatric traumatic ethmoidal roof CSF leaks using a multilayer repair technique via an endoscopic approach. Ten pediatric patients (aged 4-14 years, six males and four females) presenting with posttraumatic ethmoidal roof CSF rhinorrhea were operated upon between January 2007 and December 2010, using an endoscopic endonasal multilayer repair technique. Preoperative radiological evaluation included both multidetector computed tomography (MDCT) with ultra-thin 1mm cuts, and magnetic resonance imaging (MRI) high resolution coronal T2-weighted sequence. Intraoperatively, the GE InstaTrak™ 3500 electromagnetic navigation system was used in all cases. Postoperative follow-up was done clinically by regular endoscopic examinations and radiologically by MRI assessment using the same preoperative protocol. Clinically all patients presented with unilateral intermittent watery rhinorrhea with periods ranging from 5 to 24 months before operation. Seven cases had a history of recurrent meningitis. Defects were confined to ethmoidal roof in all 10 cases (right side in seven and left side in three), and ranged in size from 2 to 7 mm(2) (mean 3.9 ± 1.5 mm(2)). Two cases had more than one defect on the same side. All defects were identified preoperatively using our radiological protocol. One case was associated with a meningocele with no brain herniation and another case was associated with a small meningoencephalocele. Mean postoperative hospitalization was 6 days (range 4-8 days). None of our patients developed any intra or postoperative complications or required revision surgery with a 100% success rate after a mean follow-up duration of 29.4 ± 14.4 months (range 12-52 months). Pediatric posttraumatic CSF leaks involving the ethmoidal roof can be successfully managed via the endonasal endoscopic route using a multilayer repair technique, thus limiting complications associated with external approaches. Preoperative imaging including MDCT and high resolution MRI is of paramount importance for detecting the defect site and for planning surgery.

Probabilistic Safety Assessment and Management, 2004

Monte-Carlo Simulation (MCS) can have different uses in supporting structure reliability investig... more Monte-Carlo Simulation (MCS) can have different uses in supporting structure reliability investigations and assessments. In this paper we focus our interest on the use of MCS as a numerical tool to support the fitting of the experimental data related to toughness experiments.

This is a revision of (he past seven years experience in activation calculations for dismantling.... more This is a revision of (he past seven years experience in activation calculations for dismantling. It aims at evaluating lhc experience and at making better understanding to help in decision making during the following phases. Five gas cooled reactors are shutdown and arc waiting for the EDF (Electricite Dc France) dismantling decision. The sixth (BUGYl) will be shutdown by 1994 and will be wailing a dismantling decision as well.

Matrix Science Pharma, 2020

Vitamin D is a group of fat-soluble vitamins responsible for intestinal absorption of calcium and... more Vitamin D is a group of fat-soluble vitamins responsible for intestinal absorption of calcium and phosphate. Vitamin D deficiency (VDD) has reached an epidemic in both developed and developing countries. Literature review showed that population knowledge, attitude, and practice concerning Vitamin D were poor. Prescribing doctors and pharmacist are an important source of health information. Hence, their knowledge and practices about Vitamin D is essential for their roles and needs to be highlighted. Objectives: The aim of this study is to assess knowledge, attitude, and practice regarding Vitamin D among community pharmacists and prescribing doctors in Khartoum City, Sudan, 2020. Materials and Methods: An observational cross-sectional study was carried out from February to April 2020 among 94 community pharmacists and 106 prescribing doctors using a validated electronic delivery self-administered questionnaire in Khartoum locality. Results: About 32.7% and 41.9% from prescribing doctors and pharmacists had poor general knowledge, respectively, regarding VDD, while the significant trend was found regarding the level of knowledge and year of experience (P = 0.022) of all health professionals (pharmacists and doctors). About 39.3% and 44.1% from prescribing doctors and pharmacists, respectively, had poor nutrition knowledge score toward Vitamin D with a significant trend regarding nutrition knowledge score and different gender groups (P = 0.02) of all health professionals in the study. About 49.5% and 47.5% from prescribing doctors and pharmacists, respectively, had poor attitude scores toward Vitamin D with a significant trend regarding nutrition knowledge score and attitude score (P = 0.037) of all health professionals. Conclusion and Recommendations: This survey identified a gap in the general knowledge, nutritional knowledge, and attitude among health-care professionals (prescribing doctors and pharmacists).

Egyptian Journal of Radiology and Nuclear Medicine, 2020

Background Inverted papilloma (IP) is an uncommon sino-nasal neoplasm with potentially distinctiv... more Background Inverted papilloma (IP) is an uncommon sino-nasal neoplasm with potentially distinctive MRI and CT features. The MR “striated” imaging pattern has been reported as a valuable MR imaging feature of IP. The purpose of this study was to validate the usefulness of this sign using detailed criteria of the sign itself. Results All imaging findings were described for 16 patients in descriptive pattern. The nasal involvement showed highest prevalence followed by the maxillary sinus. The bony changes include remodeling and defects (n = 6), remodeling only (n = 4), and None (n = 6). Changes were severe 1/10, moderate in 3/10, and mild 5/10. Focal hyperostosis was seen in six. A striated pattern was “diffuse” in all 16 (100%) of the IPs; it followed a certain direction in all 16 patients: divergent (n = 6), convoluted (n = 2), and parallel (n = 8). Divergent growth from focal hyperostosis was seen (n = 4). Visibility of the sign was superior in T2 images (n = 11), superior in enhanc...

Journal of Molecular Liquids, 2019

Mitigation the activity of α-amylase and α-glucosidase is scientifically spotlighted to potential... more Mitigation the activity of α-amylase and α-glucosidase is scientifically spotlighted to potentially decrease the glucose absorption and scavenge category 2-diabetes mellitus in the humans. For the first time, we elucidated the underlying mechanism of the inhibitory activity of 3 structurally different phytosterols (PS) on α-amylase and α-glucosidase using multispectral and molecular docking approaches. It was found that stigmasterol, βsitosterol, and γ-oryzanol integratedly (competitive and uncompetitive) inhibited both of α-amylase and αglucosidase. The spectrofluorometric results demonstrated that a static interaction of PS with both enzymes happened, leading to the changes in Z-average size, UV-vis spectrum, and secondary structures of these amylolytic enzymes. Moreover, each PS noncovalently interacted with several residues close to the active sites of both enzymes via H-bonding and π-π forces, causing indirectly inhibition to their catalytic activity. However, γoryzanol was highly inhibited both enzymes than the other PS since its structure in which contained ferulic acid esterified with sterol, which could be used as nutraceutical ingredients.

Stereotactic and functional neurosurgery, Jan 18, 2018

The optimum target in surgery for Parkinson's disease (PD) is still controversial, especially... more The optimum target in surgery for Parkinson's disease (PD) is still controversial, especially in patients with tremor-dominant PD. We aim to compare results in tremor-dominant patients undergoing pallidotomy vs. those undergoing simultaneous posteroventral pallidotomy (PVP) and ventral intermediate nucleus (VIM) thalamotomy. Twenty-four patients with tremor-dominant PD were included in this study. Twelve patients received unilateral PVP contralateral to the most affected side. The other 12 patients received simultaneous unilateral PVP and VIM thalamotomy contralateral to the most affected side. Assessment of results in both groups was achieved using both UPDRS "off" motor scores and UPDRS rest tremor subscores. The mean UPDRS off motor score improved in the pallidotomy group from 61.3 preoperatively to 36.8 at 12 months. In the combined group, it improved from 59.6 to 35.2 at 12 months, with no statistically significant difference between both groups. On the other hand...

Studies in Systems, Decision and Control, 2016

The ultimate target of Modelling and Simulation (M&S) activities in the field of CIP is to provid... more The ultimate target of Modelling and Simulation (M&S) activities in the field of CIP is to provide Models, Methodologies and tools to help in the analysis of different crisis' scenarios and, subsequently, in crisis management decision making. A CIs' disruptions scenario is simply a sequence of random events following a well-defined chronological order. Generally, each identified scenario produces a set of consequences which is a function of: the initiating event, the concerned CIs and the geo-organizational context of the disrupted CIs. Formal sciences represent the reality of our surrounding world. But formal sciences are imperfect and what we call "reality" is the projection of the inaccessible "Reality" on our world. This projection is the only reality we are talking about in formal sciences. Subsequently, formal sciences construct objects in which small parts of the sensible reality are grasped and formalized. These objects can be called "models". We are limiting our interest here to formal sciences and engineering activities that cover both conceptual and phenomenological modelling processes. Models are first validated before being admitted in the construction of a global model of the sensible reality. Regarding our focus on crisis scenarios modelling, simulation and analysis (MS&A), engineers' ambition is to simulate not only independent isolated phenomenon but also interacting multi-physic multi-scale phenomenon. M. Eid (&) Commissariat à l'énergie atomique et aux énergies alternatives,

European Archives of Oto-Rhino-Laryngology, 2016

56 patients affected by T2 glottic carcinoma were treated in two institutes using transoral laser... more 56 patients affected by T2 glottic carcinoma were treated in two institutes using transoral laser microsurgery (TLM) in 40 cases and vertical hemilaryngectomy in 16 cases between September 2012 and September 2015. In the TLM group, different subtypes of type V cordectomy were used according to the extent of tumor. In the vertical hemilaryngectomy group, classical operation was used in most of the cases and the resection was extended in few cases. Analysis of post-operative swallowing function was done using videofluoroscopy (VFS), functional endoscopic evaluation of swallowing, and subjectively using MD Anderson dysphagia inventory. Objective evaluation of swallowing has been made by obtaining different measures from VFS (pharyngeal transit time, pharyngeal constriction ratio, and hyoid displacement for example). Analysis also included the need and duration of tracheostomy and nasogastric tube, ICU admission, and hospitalization time. Statistical analysis was performed with the Mann-Whitney U and Pearson Chi-square tests. Comparison of incidence of aspiration and swallowing outcome showed significantly better results in the laser group than in the vertical group (p < 0.001). The duration of ICU, tracheostomy, nasogastric tube, and hospital stay was also significantly shorter in the laser group (p < 0.001). This study shows that TLM had significantly better overall postoperative outcome than vertical hemilaryngectomy. It was associated with significantly shorter hospital stay and less need for tracheostomy, nasogastric tube, and ICU admission). Measures obtained from VFS are useful for detection and follow-up of postoperative aspiration, because it is a definitive technique for anatomical and physiological study of swallowing.

The Egyptian Journal of Radiology and Nuclear Medicine, 2014

Background: Subtraction imaging is a technique whereby an unenhanced T1-weighted sequence is digi... more Background: Subtraction imaging is a technique whereby an unenhanced T1-weighted sequence is digitally subtracted from the identical sequence performed after gadolinium administration. Aim of the work: This study will highlight the role of subtraction imaging for non-vascular MRI applications. Subjects and methods: The study included 40 patients presenting with lesions in different parts of the body, that are initially hyperintense on T1W sequences. We used post-processing software (Osirix) to digitally subtract the pre-enhancement from the post enhancement sequences. Results: Based on subtraction imaging findings 5 patients were diagnosed with intraocular melanomas, two patients were diagnosed with hemorrhagic cysts in the masseter muscle , two patients were diagnosed with hemorrhagic cysts in the parotid gland, two patients were diagnosed with dysplastic hepatic nodules, 5 patients were diagnosed with post-ablation necrosis following hepatocellular carcinoma (HCC) treatment, two patients showed recurrent HCC after chemoembolisation, 3 patients showed chemoembolised HCC without recurrence, 4 patients showed intraluminal gall bladder sludge, 4 patients showed hemorrhagic renal cysts, one patient showed solid papillary neoplasm of the pancreas, 6 patients showed chocolate ovarian cysts, two patient showed ovarian cystadenoma and two patients showed ovarian cystadenocarcinoma. Conclusion: Subtraction MRI is very helpful tool in non-vascular MRI applications.

The Egyptian Journal of Radiology and Nuclear Medicine, 2014

Introduction: Differentiating a benign from a malignant adnexal mass would provide a basis for op... more Introduction: Differentiating a benign from a malignant adnexal mass would provide a basis for optimal preoperative planning and may also reduce the number of unnecessary laparotomies patients undergoing treatment for benign disease. MRI provides additional information on the composition of soft-tissue masses using differences in MR relaxation properties seen in various types of tissue. More recently developed MRI sequences, like diffusion weighted, susceptibility weighted, and dynamic contrast enhancement sequences provided additional capacities for adnexal lesion tissue characterization. Aim of the work: The aim of this work was to study the role of MRI including the novel sequences, namely dynamic contrast enhanced MRI (DCE-MRI), diffusion weighted images (DWI) and susceptibility weighted images (SWI) in the characterization of ovarian masses. Patients and methods: This study included 25 patients having indeterminate adnexal masses at ultrasound. They were subjected to pelvic MRI, including T1, T2, T1 fat sat sequences, as well as the DWI, SWI, and DCE sequences. Final diagnosis was reached through histopathological data, or therapeutic response. Results: All endometriomas showed blooming on SWI. All malignant lesions showed restricted diffusion and type III DCE curves. Conclusion: MRI, especially the more recent sequences (DWI, SWI and DCE) allows accurate characterization of ovarian lesions.

The Egyptian Journal of Radiology and Nuclear Medicine, 2012

Living donor liver transplantation is increasingly being used to help compensate for the increasi... more Living donor liver transplantation is increasingly being used to help compensate for the increasing shortage of cadaveric liver grafts. However, the extreme variability of the hepatic vascular and biliary systems can impede this surgical procedure. The aim of the study is to demonstrate the role of MR cholangiopancreatography (MRCP) in the evaluation of anatomical biliary variants in potential living donors for liver transplantation. Methods: The study included 20 liver donors in pre-operative assessment before liver transplantation. MR cholangiopancreatography (MRCP) was performed for all donors. Results: The study included 20 donors (16 men and 4 women) ranging in age from 29 to 52 years. 16 (80%) donors demonstrate normal biliary branching anatomy. One donor has trifurcation biliary branching pattern (5%). Two donors have their right posterior ducts draining into the left hepatic duct (10%). One donor has low insertion of the right posterior duct into the main duct (5%). Conclusion: MR cholangiopancreatography (MRCP) provides important information in evaluation of potential living donors for liver transplantation.

The Egyptian Journal of Radiology and Nuclear Medicine, 2012

Background: GISTs are considered the commonest mesenchymal neoplasms of the GIT originating from ... more Background: GISTs are considered the commonest mesenchymal neoplasms of the GIT originating from the gastrointestinal tract, mesentery, omentum, or retroperitoneum. They arise within the gut musculosa having exophytic growth pattern. They characteristically have hemorrhage, necrosis, or cyst formation that appears as focal areas of low attenuation on computed tomographic images. With multidetector CT (MDCT) capabilities, the exact origin of the GIST can be easily confirmed to differentiate it from other mesenchymal origin tumors. Materials and methods: Retrospective search for GIST cases in the digital archives of our institute, during a 15 months duration (April 2010 to July 2011). Workstation reviewing of their imaging features. Results: This study included 24 pathologically proved GISTs (12 gastric, 8 small intestinal, two colonic, one mesenteric and one anorectal) demonstrating the radiologic features of GISTs depending on tumor size and organ of origin. Conclusion: MDCT with its multiplanar capabilities and isotropic z-axis resolution allows the radiologist to examine the detailed relation of the mass to the surrounding bowel wall, vessels and other structures. It also helps to map the vascular pedicle in cases of hypervascular GIST's, which may be crucial for trans-catheter embolization in cases presenting with acute gastrointestinal bleeding.

Strategies in Trauma and Limb Reconstruction, 2010

Sixteen patients underwent minimally invasive subtalar arthrodesis through a mini-invasive approa... more Sixteen patients underwent minimally invasive subtalar arthrodesis through a mini-invasive approach with posterior iliac graft between 2004 and 2006. No hardware was used to transfix the arthrodesis and partial weight bearing was allowed immediately. The primary indication for surgery was the squeal of fracture os calcis in terms of subtalar joint arthritis, loss of heel height, malalignment of the hindfoot, and pain with weight bearing. There were 12 male and 4 female patients with a mean age of 30 (range 17-52). Patients were followed up for a period of 40.8 months (range 36-48 months). The mean interval from injury to fusion was 2 (?0.6) years ranging from 6 months to 6 years post fracture. The average clinical rating scale based on the American Orthopaedic Foot and Ankle Society (AOFAS) improved from 36 preoperatively to 78 at the latest follow-up (P \ 0.05). Union rate was 94%. Radiographic evaluation revealed a mean increase in calcaneal inclination of 6.25 ? 8.3°(P \ 0.07) and a mean increase in the lateral talocalcaneal angle of 7.42 ? 10.2°(P \ 0.08). Complications were graft nonunion in 1 patient and transient tendoachilles tendinitis in another. This technique can be used to decrease the morbidity associated with the late complications of os calcis fractures by aligning the hindfoot, restoring the heel height and correcting calcaneal and talar inclination. It offers the advantage of early weight bearing while avoiding hardware complications.

European Journal of Orthopaedic Surgery & Traumatology, 2014

Purpose Patients with generalized hyperlaxity with frank recurrent anterior shoulder dislocation ... more Purpose Patients with generalized hyperlaxity with frank recurrent anterior shoulder dislocation had high failure rate after conservative and soft tissue stabilization procedures. Our hypothesis is that a Latarjet procedure can provide an alternative successful approach to manage such cases. Methods This prospective study was conducted on 13 patients with multiple recurrences of anterior shoulder dislocation. The mean age was 24.4 years. They all had generalized ligamentous laxity according to Beighton's scale with a mean score of six points. Hill-Sach's lesion was \20 % of the head diameter with no glenoid defect; otherwise, the case was not included in the study. The modification of Burkhart and de Beer ''congruent-arc Latarjet procedure'' was performed for all patients through a limited deltopectoral approach. Results Re-dislocation occurred in one case only over the follow-up period. It occurred once after a violent act. Their preoperative mean Rowe score was 47.5 points preoperatively and increased to 91.07 postoperatively. This improvement was statistically highly significant (p value\0.001). The mean range of postoperative external rotation was 69.29°. Conclusion Latarjet procedure provides a higher success rate in such patients with multiple recurrences regarding both shoulder stability and function compared to capsulolabral repair procedures. Level of evidence IV.

Alexandria Journal of Medicine, 2013

The study aims not only to determine the value of preoperative MRI of perianal fistula but also t... more The study aims not only to determine the value of preoperative MRI of perianal fistula but also to detect MRI fallacious results, if any. Also, it aims to suggest how we can limit such false positive MRI results that may lead to unnecessary surgery. Patients and methods: This was a prospective comparative study, included 100 patients. Fifty of them (group A) were operated following the guidance of preoperative MRI, while the other 50 patients (group B) directly operated without MRI. The study protocol was approved by the ethics committee in Al-Mana General Hospital.

International Journal of Pediatric Otorhinolaryngology, 2012

Pediatric traumatic cerebrospinal fluid (CSF) leak is a challenging problem in diagnosis and mana... more Pediatric traumatic cerebrospinal fluid (CSF) leak is a challenging problem in diagnosis and management. Posttraumatic leaks frequently present by intermittent rhinorrhea or by recurrent attacks of meningitis, which can be the only presenting symptom. The objective of this study is to present our experience in management of pediatric traumatic ethmoidal roof CSF leaks using a multilayer repair technique via an endoscopic approach. Ten pediatric patients (aged 4-14 years, six males and four females) presenting with posttraumatic ethmoidal roof CSF rhinorrhea were operated upon between January 2007 and December 2010, using an endoscopic endonasal multilayer repair technique. Preoperative radiological evaluation included both multidetector computed tomography (MDCT) with ultra-thin 1mm cuts, and magnetic resonance imaging (MRI) high resolution coronal T2-weighted sequence. Intraoperatively, the GE InstaTrak™ 3500 electromagnetic navigation system was used in all cases. Postoperative follow-up was done clinically by regular endoscopic examinations and radiologically by MRI assessment using the same preoperative protocol. Clinically all patients presented with unilateral intermittent watery rhinorrhea with periods ranging from 5 to 24 months before operation. Seven cases had a history of recurrent meningitis. Defects were confined to ethmoidal roof in all 10 cases (right side in seven and left side in three), and ranged in size from 2 to 7 mm(2) (mean 3.9 ± 1.5 mm(2)). Two cases had more than one defect on the same side. All defects were identified preoperatively using our radiological protocol. One case was associated with a meningocele with no brain herniation and another case was associated with a small meningoencephalocele. Mean postoperative hospitalization was 6 days (range 4-8 days). None of our patients developed any intra or postoperative complications or required revision surgery with a 100% success rate after a mean follow-up duration of 29.4 ± 14.4 months (range 12-52 months). Pediatric posttraumatic CSF leaks involving the ethmoidal roof can be successfully managed via the endonasal endoscopic route using a multilayer repair technique, thus limiting complications associated with external approaches. Preoperative imaging including MDCT and high resolution MRI is of paramount importance for detecting the defect site and for planning surgery.

Probabilistic Safety Assessment and Management, 2004

Monte-Carlo Simulation (MCS) can have different uses in supporting structure reliability investig... more Monte-Carlo Simulation (MCS) can have different uses in supporting structure reliability investigations and assessments. In this paper we focus our interest on the use of MCS as a numerical tool to support the fitting of the experimental data related to toughness experiments.