muhammad asif - Academia.edu (original) (raw)

Papers by muhammad asif

Asian Pacific Journal of Cancer Prevention Apjcp, 2010

The rationale of this study is to analyze the demographic distribution and clearance of excision ... more The rationale of this study is to analyze the demographic distribution and clearance of excision margin in basal cell carcinoma among patients diagnosed at AFIP Rawalpindi. Records of a total of 235 cases diagnosed from January 2005 to December 2007 were retrieved from our tumour registry. The following variables were recorded for each patient: age, gender, site of biopsy, type of biopsy (incisional vs excisional) and status of clearance of surgical margins. The data was analyzed using SPSS version 17.0. Among the total of 235 cases, 125 (53.2%) were males and 110 (46.8%) were females (1.2:1). The ages ranged from 32 to 90 years with mean age of 60.0 + 11.7, with a general age-dependent increase. The nose was the most frequent site (28.9%), followed by the eye, including the orbit (24.7%), and the cheek (20.4%). Among the type of biopsies, 140 (59.6%) were excisional and 95 (40.4%) were incisional. With the former, the excision margins were reported as clear in 82 (34.9%) cases and involved in 55 (23.4%) cases. Basal cell carcinoma (BCC) appears to be on the rise in our part of world. Careful clinical assessment, and complete excision with the help of frozen sections can avoid recurrence.

In this paper, a simple active contour based visual tracking algorithm is presented for outdoor A... more In this paper, a simple active contour based visual tracking algorithm is presented for outdoor AGV application which is currently under development at the USM robotic research group (URRG) lab. The presented algorithm is computationally low cost and able to track road boundaries in an image sequence and can easily be implemented on available low cost hardware. The proposed algorithm

Value Health, 2011

OBJECTIVES: Non-adherence to insulin therapy in patients with type 2 diabetes presents a serious ... more OBJECTIVES: Non-adherence to insulin therapy in patients with type 2 diabetes presents a serious challenge. Potential explanations for non adherence may include aversion to insulin self-injection and fear of hypoglycemic events. In clinical trails, insulin analogs have shown to reduce the risk of hypoglycemic events versus human insulins, and a recent review suggests that insulin delivered via a pen device may result in greater adherence versus vial and syringe. This study was conducted to compare the adherence rates of patients initiating basal insulin therapy with insulin detemir (IDet) FlexPen® versus those initiating basal insulin therapy with NPH via vial and syringe. METHODS: Data were gathered from a large US national payer retrospective claims database, and included only patients with type 2 diabetes that initiated basal insulin therapy with either IDet FlexPen® or NPH in vials. Patients with claims for any other type of insulin, other than the index insulin formulations during the 12-month observation period were excluded. Patients were defined as being adherent to therapy if they had a medication possession ration (MPR) of at least 0.80 in the 12-month follow up period. RESULTS: The IDet FlexPen® cohort (nϭ1082) and the NPH vial cohort (nϭ794) were of similar age (54.06 vs. 53.13, pϭ0.134); however, the IDet FlexPen® cohort had a lower proportion of female patients (44% vs. 55%, pϽ0.001) and fewer patients without a history of pre-index OADs (9% vs 45%, pϽ0.001), than the NPH vial cohort. After controlling for important confounders, patients initiating insulin therapy with IDet FlexPen® were 39% more likely to achieve an MPR of 0.80 or greater versus patients initiating insulin therapy with NPH vial (95% CI: 1.04-1.85). CONCLUSIONS: These results suggest that adherence may be improved for patients initiating basal insulin therapy with IDet in the FlexPen® versus NPH in a vial.

Value Health, 2011

To determine the status, practices and perception of self-medication among general population of ... more To determine the status, practices and perception of self-medication among general population of Quetta city, Pakistan. METHODS: Convenience sample was taken from respondents that were patrons of community pharmacies. A questionnaire about status, knowledge and perception against self medication was constructed, content validated and used for data collection. Pharmacists were hired for data collection and analyses were done by SPSS 15. RESULTS: A total of 840 patrons were approached and 784 responded (93.33%). 621 (79.20%) were males and 163 (20.79%) were females. Most respondents (74.25%) admitted to practice of self medication. Males were found to self medicate more (84.36%) than females (15.63%). Practices of self medication were found more in age group of 35-44 (32.27%). Body weakness/sexual problems (21.80%) were the major conditions for which self medication was performed. Multivitamins/sexual performance enhancer (22.36%), NSAIDS (17.65%) and antibiotics (15.32%) were commonly used drugs. Information related to the medicines was taken from people with past exposure (25.90%), chemist/pharmacist (20.50%) and family member (18.75%). Most patients (18.55%) described high physician expenses as the cause of their self medication. A total of 15.67% of the respondents revealed that they trust chemists and pharmacists more due to their past experiences. A total of 66.65% of population perceived that self medication helps them save money while 61.25% believed that self medication is harmless. CONCLUSIONS: Educational campaigns to educate the population about the rational use of medications are needed. The healthcare professionals must pay special attention on this issue. In addition, sale of medicines without prescriptions should be strictly prohibited and monitored by regulatory authorities.

ABSTRACT Pakistan has distinct domestic pigeon breeds which have been bred for centuries. This st... more ABSTRACT Pakistan has distinct domestic pigeon breeds which have been bred for centuries. This study aimed to identify novel Single Nucleotide Polymorphisms (SNPs) in Cytochrome b (Cytb) gene of a unique Pakistani domestic pigeon named as Sherazi for its molecular classification. The full-length Cytb gene of the Pakistani domestic pigeon (n=25) was sequenced. Five novel SNPs sites were identified in the Cytb gene of the Pakistani domestic pigeon after comparing with those of Rock Pigeon (Columbia livia). The phylogenetic analysis, using the Cytb gene sequences of Pakistani domestic pigeon and all the available Columbiformes, revealed that C. livia is the ancestor of the Pakistani domestic pigeon albeit the Pakistani domestic pigeon differs phenotypically from it. The novel SNPs in Cytb gene of the Sherazi pigeon can serve as a genetic marker for identification, phylogentic analysis and evolutionary characterization of pigeon species. This is the first report of SNP identification of Cytb gene of the Pakistani domestic pigeon and its molecular classification

Arch Appl Mech, 1990

The stability of miscible fluid displacement through porous media has been investigated when conc... more The stability of miscible fluid displacement through porous media has been investigated when concentration induced density and viscosity gradients are present. The dependence of Rayleigh's number on the horizontal planform of cellular motion is established and it is shown that the l~ayleigh and wave numbers interact in a nonlinear fashion and henee have to be treated as two independent parameters in the analysis of stability process.

We adopted the technique of response surface methodology (RSM) for maximum alkaline protease prod... more We adopted the technique of response surface methodology (RSM) for maximum alkaline protease production by Bacillus subtilis during the fermentation process. In RSM, Central Composite Design (CCD) was chosen involving 2 5 full factorial half fractions which were based on 32 independent experiments using various combinations of five nutrient sources at one time. The nutrients provided in the medium were, glucose as carbon source, peptone as nitrogen source, potassium iodine as K source, sodium phosphate as P source, while zinc sulfate and magnesium sulfate were included for provision of micronutrients. The data collected was analyzed through computer-based statistics software SPSS 16. The multiple linear regression model equation was articulated by the coefficient of the determination R 2 and statistical significance of the variables were checked by p value (<0.05).

Microsatellites are the target sequences of choice for a wide range of applications in genomics f... more Microsatellites are the target sequences of choice for a wide range of applications in genomics for genotyping, genome mapping, QTL analysis and assessment of genetic diversity. We have effectively employed MetaPhor agarose gel electrophoresis (MAGE) for genotyping with microsatellite markers. Separation of SSRs on MetaPhor agarose gels appeared to be easier and economical. By employing MAGE, we were successful to clearly separate SSR alleles with a size difference of five bp. MAGE is a reliable and appropriate approach for identification of small length polymorphisms while screening large number of samples, therefore it is a valuable tool for the researchers involved in DNA fingerprinting work with microsatellite markers.

Cereal Foods World, 2010

Abstract The impact of four thermal processing methods oil rice bran stabilization, oil extractio... more Abstract The impact of four thermal processing methods oil rice bran stabilization, oil extraction, and nutrient destruction was compared. All of the processing equipments, except the pellet mill, had a positive effect oil rice bran stabilization. Maximum Oil (204 g/kg) was ...

The aim of the study was to determine the concentration of copper in serum of human blood by usin... more The aim of the study was to determine the concentration of copper in serum of human blood by using flame atomic absorption spectroscopy (FAAS). As far as the global environmental health issues are concerned, there are many factors that are directly or indirectly affect human health and society and the deficiency or toxicity of different metals in human blood is one of them. Some trace metals such as copper, zinc, iron and manganese are essential for maintaining good human health whereas, different heavy metals like mercury, molybdenum and lead can affect human health badly. Copper is one of the metals that have coordination with zinc and iron to maintain their absorption, storage, and metabolism, also strengthen skin and blood vessels . The exposure of copper in environment is commonly due to welding, plumbing and such areas where copper fumes are mostly inhaled [1] that caused copper concentration increased in human blood which may leads to common diseases like anemia, liver damage, anxiety, allergies. In this study we analyzed the effects of copper on human health, by determining its concentration in human blood serum which was done on the flame atomic absorption spectroscopy (FAAS) that give the amount of copper present in serum as results. The 45 blood samples were collected from welders, plumbers and flood victims (15 each), so that we were able to know any related cause of disease or risk due to improper concentration of copper.

Ieee International Conference on Image Processing 2005, Oct 14, 2005

SIPL, Department of Mechatronics, Gwangju Institute of Science and Technology (GIST), 1 Oryong-do... more SIPL, Department of Mechatronics, Gwangju Institute of Science and Technology (GIST), 1 Oryong-dong, Buk-gu, Gwangju 500-712, Korea. (e-mail: asif@lge.com, aamir@gist.ac.kr, tschoi@gist.ac.kr) ... 1 The author is with the Digital TV Laboratory, LG Electronics Co. ...

Journal Chemical Society of Pakistan, Apr 13, 2005

2014 13th International Conference on Control Automation Robotics Vision, Dec 1, 2014

Multiple Sclerosis, Jun 1, 2007

Journal Chemical Society of Pakistan, Aug 22, 2008

2014 14th International Conference on Computational Science and Its Applications, Jun 1, 2014

Asian Pacific Journal of Cancer Prevention Apjcp, 2010

The rationale of this study is to analyze the demographic distribution and clearance of excision ... more The rationale of this study is to analyze the demographic distribution and clearance of excision margin in basal cell carcinoma among patients diagnosed at AFIP Rawalpindi. Records of a total of 235 cases diagnosed from January 2005 to December 2007 were retrieved from our tumour registry. The following variables were recorded for each patient: age, gender, site of biopsy, type of biopsy (incisional vs excisional) and status of clearance of surgical margins. The data was analyzed using SPSS version 17.0. Among the total of 235 cases, 125 (53.2%) were males and 110 (46.8%) were females (1.2:1). The ages ranged from 32 to 90 years with mean age of 60.0 + 11.7, with a general age-dependent increase. The nose was the most frequent site (28.9%), followed by the eye, including the orbit (24.7%), and the cheek (20.4%). Among the type of biopsies, 140 (59.6%) were excisional and 95 (40.4%) were incisional. With the former, the excision margins were reported as clear in 82 (34.9%) cases and involved in 55 (23.4%) cases. Basal cell carcinoma (BCC) appears to be on the rise in our part of world. Careful clinical assessment, and complete excision with the help of frozen sections can avoid recurrence.

In this paper, a simple active contour based visual tracking algorithm is presented for outdoor A... more In this paper, a simple active contour based visual tracking algorithm is presented for outdoor AGV application which is currently under development at the USM robotic research group (URRG) lab. The presented algorithm is computationally low cost and able to track road boundaries in an image sequence and can easily be implemented on available low cost hardware. The proposed algorithm

Value Health, 2011

OBJECTIVES: Non-adherence to insulin therapy in patients with type 2 diabetes presents a serious ... more OBJECTIVES: Non-adherence to insulin therapy in patients with type 2 diabetes presents a serious challenge. Potential explanations for non adherence may include aversion to insulin self-injection and fear of hypoglycemic events. In clinical trails, insulin analogs have shown to reduce the risk of hypoglycemic events versus human insulins, and a recent review suggests that insulin delivered via a pen device may result in greater adherence versus vial and syringe. This study was conducted to compare the adherence rates of patients initiating basal insulin therapy with insulin detemir (IDet) FlexPen® versus those initiating basal insulin therapy with NPH via vial and syringe. METHODS: Data were gathered from a large US national payer retrospective claims database, and included only patients with type 2 diabetes that initiated basal insulin therapy with either IDet FlexPen® or NPH in vials. Patients with claims for any other type of insulin, other than the index insulin formulations during the 12-month observation period were excluded. Patients were defined as being adherent to therapy if they had a medication possession ration (MPR) of at least 0.80 in the 12-month follow up period. RESULTS: The IDet FlexPen® cohort (nϭ1082) and the NPH vial cohort (nϭ794) were of similar age (54.06 vs. 53.13, pϭ0.134); however, the IDet FlexPen® cohort had a lower proportion of female patients (44% vs. 55%, pϽ0.001) and fewer patients without a history of pre-index OADs (9% vs 45%, pϽ0.001), than the NPH vial cohort. After controlling for important confounders, patients initiating insulin therapy with IDet FlexPen® were 39% more likely to achieve an MPR of 0.80 or greater versus patients initiating insulin therapy with NPH vial (95% CI: 1.04-1.85). CONCLUSIONS: These results suggest that adherence may be improved for patients initiating basal insulin therapy with IDet in the FlexPen® versus NPH in a vial.

Value Health, 2011

To determine the status, practices and perception of self-medication among general population of ... more To determine the status, practices and perception of self-medication among general population of Quetta city, Pakistan. METHODS: Convenience sample was taken from respondents that were patrons of community pharmacies. A questionnaire about status, knowledge and perception against self medication was constructed, content validated and used for data collection. Pharmacists were hired for data collection and analyses were done by SPSS 15. RESULTS: A total of 840 patrons were approached and 784 responded (93.33%). 621 (79.20%) were males and 163 (20.79%) were females. Most respondents (74.25%) admitted to practice of self medication. Males were found to self medicate more (84.36%) than females (15.63%). Practices of self medication were found more in age group of 35-44 (32.27%). Body weakness/sexual problems (21.80%) were the major conditions for which self medication was performed. Multivitamins/sexual performance enhancer (22.36%), NSAIDS (17.65%) and antibiotics (15.32%) were commonly used drugs. Information related to the medicines was taken from people with past exposure (25.90%), chemist/pharmacist (20.50%) and family member (18.75%). Most patients (18.55%) described high physician expenses as the cause of their self medication. A total of 15.67% of the respondents revealed that they trust chemists and pharmacists more due to their past experiences. A total of 66.65% of population perceived that self medication helps them save money while 61.25% believed that self medication is harmless. CONCLUSIONS: Educational campaigns to educate the population about the rational use of medications are needed. The healthcare professionals must pay special attention on this issue. In addition, sale of medicines without prescriptions should be strictly prohibited and monitored by regulatory authorities.

ABSTRACT Pakistan has distinct domestic pigeon breeds which have been bred for centuries. This st... more ABSTRACT Pakistan has distinct domestic pigeon breeds which have been bred for centuries. This study aimed to identify novel Single Nucleotide Polymorphisms (SNPs) in Cytochrome b (Cytb) gene of a unique Pakistani domestic pigeon named as Sherazi for its molecular classification. The full-length Cytb gene of the Pakistani domestic pigeon (n=25) was sequenced. Five novel SNPs sites were identified in the Cytb gene of the Pakistani domestic pigeon after comparing with those of Rock Pigeon (Columbia livia). The phylogenetic analysis, using the Cytb gene sequences of Pakistani domestic pigeon and all the available Columbiformes, revealed that C. livia is the ancestor of the Pakistani domestic pigeon albeit the Pakistani domestic pigeon differs phenotypically from it. The novel SNPs in Cytb gene of the Sherazi pigeon can serve as a genetic marker for identification, phylogentic analysis and evolutionary characterization of pigeon species. This is the first report of SNP identification of Cytb gene of the Pakistani domestic pigeon and its molecular classification

Arch Appl Mech, 1990

The stability of miscible fluid displacement through porous media has been investigated when conc... more The stability of miscible fluid displacement through porous media has been investigated when concentration induced density and viscosity gradients are present. The dependence of Rayleigh's number on the horizontal planform of cellular motion is established and it is shown that the l~ayleigh and wave numbers interact in a nonlinear fashion and henee have to be treated as two independent parameters in the analysis of stability process.

We adopted the technique of response surface methodology (RSM) for maximum alkaline protease prod... more We adopted the technique of response surface methodology (RSM) for maximum alkaline protease production by Bacillus subtilis during the fermentation process. In RSM, Central Composite Design (CCD) was chosen involving 2 5 full factorial half fractions which were based on 32 independent experiments using various combinations of five nutrient sources at one time. The nutrients provided in the medium were, glucose as carbon source, peptone as nitrogen source, potassium iodine as K source, sodium phosphate as P source, while zinc sulfate and magnesium sulfate were included for provision of micronutrients. The data collected was analyzed through computer-based statistics software SPSS 16. The multiple linear regression model equation was articulated by the coefficient of the determination R 2 and statistical significance of the variables were checked by p value (<0.05).

Microsatellites are the target sequences of choice for a wide range of applications in genomics f... more Microsatellites are the target sequences of choice for a wide range of applications in genomics for genotyping, genome mapping, QTL analysis and assessment of genetic diversity. We have effectively employed MetaPhor agarose gel electrophoresis (MAGE) for genotyping with microsatellite markers. Separation of SSRs on MetaPhor agarose gels appeared to be easier and economical. By employing MAGE, we were successful to clearly separate SSR alleles with a size difference of five bp. MAGE is a reliable and appropriate approach for identification of small length polymorphisms while screening large number of samples, therefore it is a valuable tool for the researchers involved in DNA fingerprinting work with microsatellite markers.

Cereal Foods World, 2010

Abstract The impact of four thermal processing methods oil rice bran stabilization, oil extractio... more Abstract The impact of four thermal processing methods oil rice bran stabilization, oil extraction, and nutrient destruction was compared. All of the processing equipments, except the pellet mill, had a positive effect oil rice bran stabilization. Maximum Oil (204 g/kg) was ...

The aim of the study was to determine the concentration of copper in serum of human blood by usin... more The aim of the study was to determine the concentration of copper in serum of human blood by using flame atomic absorption spectroscopy (FAAS). As far as the global environmental health issues are concerned, there are many factors that are directly or indirectly affect human health and society and the deficiency or toxicity of different metals in human blood is one of them. Some trace metals such as copper, zinc, iron and manganese are essential for maintaining good human health whereas, different heavy metals like mercury, molybdenum and lead can affect human health badly. Copper is one of the metals that have coordination with zinc and iron to maintain their absorption, storage, and metabolism, also strengthen skin and blood vessels . The exposure of copper in environment is commonly due to welding, plumbing and such areas where copper fumes are mostly inhaled [1] that caused copper concentration increased in human blood which may leads to common diseases like anemia, liver damage, anxiety, allergies. In this study we analyzed the effects of copper on human health, by determining its concentration in human blood serum which was done on the flame atomic absorption spectroscopy (FAAS) that give the amount of copper present in serum as results. The 45 blood samples were collected from welders, plumbers and flood victims (15 each), so that we were able to know any related cause of disease or risk due to improper concentration of copper.

Ieee International Conference on Image Processing 2005, Oct 14, 2005

SIPL, Department of Mechatronics, Gwangju Institute of Science and Technology (GIST), 1 Oryong-do... more SIPL, Department of Mechatronics, Gwangju Institute of Science and Technology (GIST), 1 Oryong-dong, Buk-gu, Gwangju 500-712, Korea. (e-mail: asif@lge.com, aamir@gist.ac.kr, tschoi@gist.ac.kr) ... 1 The author is with the Digital TV Laboratory, LG Electronics Co. ...

Journal Chemical Society of Pakistan, Apr 13, 2005

2014 13th International Conference on Control Automation Robotics Vision, Dec 1, 2014

Multiple Sclerosis, Jun 1, 2007

Journal Chemical Society of Pakistan, Aug 22, 2008

2014 14th International Conference on Computational Science and Its Applications, Jun 1, 2014