muhsin jamil abdulwahid - Academia.edu (original) (raw)

Papers by muhsin jamil abdulwahid

Current research in nutrition and food science, Apr 25, 2023

PolyTechnic, Nov 16, 2023

BioMed Target Journal, Dec 29, 2023

Most of the world's population relies on medicinal plants as their main source of healthcare.... more Most of the world's population relies on medicinal plants as their main source of healthcare. Therefore, it is crucial to ascertain the amount of heavy metals accumulated in medicinal plants. In this study, elements (Ca, P, Mg, Na, K, S, Fe, Cu, Zn, Se, Cd, V, Cr, Ni, Ag, Be, Sr, Ba, Al, Pb, Bi, Rb, B, As, and Sb) found in Celtis tournefortii Lam and Prosopis farcta that were gathered from the Mazne sub-district of Kurdistan in Iraq were identified. Using inductively coupled plasma mass spectrometry (ICP-MS) and inductively coupled plasma optical emission spectrometry (ICP-OES), concentrations of 25 elements in the leaves, fruit (Celtis tournefortii Lam), pod, and seed (Prosopis farcta) were identified. An exploratory study of samples was conducted using principal component analysis (PCA) and hierarchical cluster analysis (HCA). For Cd, Cr, Ni, Pb, and As. The elements quantified by ppm are: Ca (3403–81948), Mg (1573–7578 ), Na (108–291), K (6481–23212), Fe (184–623), Cu (8–16),...

Cellular and Molecular Biology, Apr 20, 2020

Diabetic foot infection is considered to be one of the most important medical, economic, and soci... more Diabetic foot infection is considered to be one of the most important medical, economic, and social problems and a major cause of morbidity and mortality. Proteus mirabilis is a common etiologic agent of diabetic foot infections. This study aimed to determine the prevalence of beta-lactamase genes in P. mirabilis recovered from patients with diabetic foot wounds in Erbil, Iraq. Eighteen P. mirabilis isolated from 84 patients with diabetic foot ulcers were first phenotypically examined for the existence of extended-spectrum beta-lactamases by combined disc method and double-disc synergy method that all isolates showed positive results by both methods. The results were confirmed genetically by PCR to detect beta-lactamase-encoding genes (bla TEM , bla SHV , bla CTX-M , bla OXA , and bla DHA). The results revealed that all isolates contained extended-spectrum beta-lactamase and that 80% of the P. mirabilis isolates contained bla DHA , 60% had bla TEM , 53.3% had bla OXA , and 26.7% had bla CTX-M , whereas no isolates harbored bla SHV. The coexistence of two or more beta-lactamase genes in one isolate was observed. The existence of four genes (bla TEM + bla CTX-M + bla OXA + bla DHA) in the same isolate was documented in two isolates. In conclusion, this is the first study that reports a high prevalence of bla DHA and the coexistence of four resistance genes in the same organism in P. mirabilis isolated from diabetic foot patients in Iraq.

BioMed Target Journal

Infertility is a disorder of the reproductive system characterized by a couple's inability to... more Infertility is a disorder of the reproductive system characterized by a couple's inability to conceive after at least one year of regular, unprotected sexual activity. Approximately 15% of couples worldwide struggle with infertility. Male infertility accounts for 20–30% of all infertility cases and is defined as the inability of a male to achieve conception in a healthy, fertile female. Azoospermia factor (AZF) genes are located on the long arm of the human Y chromosome and are involved in spermatogenesis. Microdeletions in the AZF region are now recognized as the second most prevalent genetic cause of spermatogenetic failure and male infertility. This study aims to diagnose AZF deletions in 289 males with infertile azoospermia and 50 males with fertile sperm using two PCR techniques, real-time PCR and gel-based PCR, and compare the results of both techniques. In diagnosing AZF deletions, the results of both real-time PCR and gel-based PCR are identical. Generally AZF deletion f...

Baghdad Science Journal, Dec 1, 2022

Infertility is a disease of the reproductive system defined by the failure to achieve a clinical ... more Infertility is a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse. Worldwide, infertility affects approximately 15% of all couples trying to conceive. Male infertility is responsible for about 50% of the infertility cases. Chromosomal abnormalities and Y-chromosome microdeletions are the most common genetic causes of male infertility. Klinefelter syndrome (KS) is the most prevalent factor of the chromosomal abnormality in the infertile male. Azoospermia Factor (AZF) microdeletions located on the Y chromosome are one of the recurrent genetic cause of male infertility. This study aims to investigate the prevalence of chromosomal anomalies and AZF microdeletions in 296 infertile Kurdish men in Erbil province, 289 patients diagnosed as azoospermia (97.6%) and 7 patients as severe oligozoospermia (2.4%) and 50 healthy men as control group. Twenty nine patients (9.8%) had various chromosomal abnormalities. The most common chromosomal abnormalities were found in sex chromosomes (93.1%; 29/27), among these abnormalities 20 patients (69%) had Klinefelter syndrome 47,XXY karyotype, 4 patients (13.8%) had 45X0/46, Xder(Y), 2 patients (6.9%) had XXY t(11;22)(q25;q13) and 1 patients (3.4%) had Mosaic Turner syndrome 46XY/45X0. The autosomal chromosomal abnormalities (6.9%; 2/29) detected in 2 patients 45, XY, rob (13;14) (q10;q10). Y chromosome microdeletions were found in 10 of 289 patients with azoospermia (3.5%), three of them (30%) had microdeletions in the AZFc region, 3 of them (30%) had microdeletions in the AZFb region, also other 3 patients had microdeletions in the b and c of AZF (AZF b,c) region, and the final one patient (10%) had microdeletions in the all a, b and c (AZF a,b,c) region. Combined Y chromosome microdeletions and chromosomal abnormalities were detected in 3 patients.

Journal of Pharmacy & Pharmacognosy Research

Context: The current study, the first of its type, focuses on the ethnobotanical uses of 97 medic... more Context: The current study, the first of its type, focuses on the ethnobotanical uses of 97 medicinal plant species by the inhabitants in the Soran area, Kurdistan region of Iraq. Aims: To evaluate local knowledge of medicinal plants and provision of preliminary data on the user-benefit of the accessible plant species in the area. Methods: Between October 2021 and May 2022, key informant interviews were conducted as part of an ethnobotanical survey. Information about a particular study through face-to-face interviews with 171 participants (98 males and 73 females) were collected. For the therapeutic plants considered in the study, quantitative indices such as use value (UV), family use value (FUV), the relative frequency of citation (RFC), fidelity level (FL), and informant consensus factor (ICF) were applied in addition to detailed notes on each plant species. Results: The survey discovered 97 plant species and 41 plant families. Leaves were the plant portion that was used the most...

Hypertension is a multifactorial and polygenic disorder where several susceptible genes interact ... more Hypertension is a multifactorial and polygenic disorder where several susceptible genes interact with the environmental factors. Endothelial nitric oxide synthase (eNOS) produces nitric oxide (NO) which is involved in many physiologic regulatory functions. Variable number of tandem repeats in intron 4 of endothelial nitricoxide synthase gene are reported to be associated with blood pressure regulation. In the present study, we examined possible association between the 27 base pair (bp) repeat polymorphism in intron 4 of the eNOS3 gene and hypertension in a Kurdish population from Erbil city. Fifty eight patients with hypertension and 42 apparently healthy controls were included in the study. Genotyping was performed by polymerase chain reaction (PCR). The genotype frequencies for eNOS4b/b, eNOS4a/b and eNOS4a/a were 55%, 23.8% and 21.2% in control group, and 70.7%, 24.2% and 5.1% in hypertensive group, respectively. The eNOS bb genotype (70.7%vs 55%) was found to be significantly as...

Science Journal of University of Zakho, 2017

A peptic ulcer is one of the more severe diseases and most classic treatment protocol produce adv... more A peptic ulcer is one of the more severe diseases and most classic treatment protocol produce adverse drug reactions. Therefore, this study aimed to examine the therapeutic effects of two natural extracts, namely Pomegranate and Ginger, on indomethacin-induced gastric ulcer in rats. Animals were divided into five groups; 1. Normal control group, 2. An ulcer control group Indomethacin (0.3 mg /rats), 3. Omeprazole (3 mg /rats), a4. Pomegranate (40 mg /rats), 5. Ginger (20 mg /rats). The ulcers were induced made from groups 2 - 5 by oral administration of Indomethacin. Rats subjected to indomethacin administration showed significant ulceration in the glandular area of their stomachs compared to normal control rats. In addition, significant elevations S.GPT, S.GOT, S. creatinine and S. Urea (P< 0.05) were observed. Alternatively, pretreatment with pomegranate and ginger significantly corrected macroscopic and biochemical parameters. These results demonstrate that administration of ...