nesrin özsoy - Academia.edu (original) (raw)

Papers by nesrin özsoy

Bu calismada periodontitisli hastalarda diseti dokusundaki notrofil lokositler incelenmistir. Biy... more Bu calismada periodontitisli hastalarda diseti dokusundaki notrofil lokositler incelenmistir. Biyopsi materyalleri yetiskin periodontitisli uc hastadan ameliyat aninda elde edilmistir. Doku biyopsilerinden hazirlanan kesitler isik ve elektron mikroskobunda incelenmistir. Iltihaplanmamis disetlerinde oral epitelin normal yapisini korudugu gozlenmistir. Bazi dejeneratif olusumlar iltihapli diseti epiteli ve bag dokusunda gorulmustur. Sulkular epitelde parakeratotik gorunus, bol miktarda rete peg yapilari, epitel alti iltihabi hucre infiltrasyonu gozlenmistir. Cep epitelinde rete peg yapilari, genislemis interseluler araliklar, interseluler koprulerin sayisinda azalma, iltihabi hucre infiltrasyonunda artis gibi bazi yapisal degisiklikler saptanmistir. Polimorfonukleer lokositler epitelin genis interseluler araliklarindaki kadar cep epiteli ve cep epiteline yakin damarlar icerisinde nadiren gozlenmistir. Epitel alti bag doku lezyonlarinda fibroblastlar, makrofajlar, mast hucreleri, lenfositler, plazma hucreleri ve az sayida polimorfonukleer lokositler gozlenmistir. Bundan baska elektron mikrograflannda plak mikroorganizmalarini fagosite eden polimorfonukleer lokositler ve doku artiklari arasinda makrofaj pseudopodlari teshis edilmistir. Abstract In this study, neutrophil leuckocytes within the gingival tissue in periodonti tis patients were examined. Biopsy materials were obtained from three adult perio dontitis patient during the operation. The sections prepared from tissue biopsies were studied by light and electron microscopy. It is observed that oral epithelium maintains it's normal structure in uninflammed gingiva. Some degenerative formations have appeared in inflamed gingival epithelium and connective tissue. Parakeratotic aspect, many rete peg formations and subepithelial inflammatory cells infiltrations were observed in the sulcular epithelium. In the pocket epithelium some structural altera tions as rete peg formations, enlargements of intercellular spaces, a decreased number of intercellular bridges and increased infiltration of inflammatory cells, have been determined. Polymorphonuclear leukocytes were rarely observed within the pocket epithelium and it's adjacent vessels, as well as, wide intercellular spaces of the epithelium. In the subepithelial connective tissue lesions, fibroblast, macrophages, mast cells, lymphocytes, plasma cells and few polymorphonuclear leukocytes were observed. Furthermore in electron micrographs, the polymorphonuclear leukocytes that phagocytized the plaque microorganisms and the pseudopodia of macrophages through tissue debris were determined.

Pharmacological Research, 2003

The effects of chronic alcohol consumption on myocardial ischemia and gas perfusion with 95% O 2-... more The effects of chronic alcohol consumption on myocardial ischemia and gas perfusion with 95% O 2-5% CO 2 were investigated in isolated rat heart. Eighteen adult male Wistar rats were used. Rats were assigned into six groups for each group to contain three rats: normal, alcoholic, normal ischemic, alcoholic ischemic, normal ischemic and 95% O 2-5% CO 2 perfused, alcoholic ischemic and 95% O 2-5% CO 2 perfused, respectively. Alcohol (7.2%, v/v) was given to rats by a modified liquid diet for 21 days. Rats were anaesthetized with ketamine (1-2 mg kg −1). Hearts were quickly isolated. Normal and alcoholic rat hearts were directly sent to the electron microscopic preparation. The other hearts were cut into small pieces and put into Krebs solution. The solution was continuously bubbled using 95% N 2-5% CO 2 20 min for ischemia. After removal of normal ischemic and alcoholic ischemic heart specimens for electron microscopic examination, the remaining hearts of the last two groups were bubbled with 95% O 2-5% CO 2 for another 20 min for the purpose of reperfusion and then were also prepared for electron microscopic examination. The hearts were investigated with a transmission electron microscope (Jeol 100 CXII TEM). Twenty-one days of chronic alcohol consumption was found to have no significant effect on myocardial ischemia determined by transmission electron microscopic examination. Our results suggest that there is no significant relationship between 21 days of alcohol consumption by a liquid diet and myocardial protection.

"Values Education", which added to Mathematics Teaching Program at the Turkish Academic Year of 2... more "Values Education", which added to Mathematics Teaching Program at the Turkish Academic Year of 2017-2018, is revised and updated as "Our Values" on January of 2018. "Our Values" based on a grown value system that aims to maintain the existence of societies preserve the unity and togetherness of societies and have the real educational success like every stage of individuals' life. The Ministry of National Education has determined the base values, which should be gained during the education of Mathematics, as justice, friendship, honesty, patience, respect, love, responsibility, patriotism and helpfulness. The aim of this study is making the students realize their own values and making them gain the helpfulness values by using creative drama activities during the education of Mathematics. In this study, "helpfulness value", which is under the topic of "Our Values" of Mathematics Teaching Program, was tried to put into practise by creative drama activities. In the study, experimental method which contains pretested and postested control group is used in order to show the behaviour difference between experimental group, which activity based creative drama method was applied, and the control group, which activity based creative drama method was not applied. This study is designed as a controlled experimental study with pretest-posttest. The group of study was consisted 106 students, which studying in 3 different provinces (Aydın, Afyon, Uşak) in the same region. Both experimental and control group was consisted by 53 students. In the study, data were collected from "helpfulness scale" which developed by Demirci (2017). As a result of the study, the helpfulness scale score of experimental group, which activity based creative drama was

The purpose of this study is to determine the effect of learning together technique of cooperativ... more The purpose of this study is to determine the effect of learning together technique of cooperative learning method on student’ mathematics achievement. The study was an experimental research in which pre-test – post-test design with control group was applied. The study was conducted in spring 2004 with 70 pupils

European Journal of Education Studies, 2018

Geometry holds an important place in the developmental process of mathematical thinking. When geo... more Geometry holds an important place in the developmental process of mathematical thinking. When geometry is the subject in mathematics lessons, it is seen by students as an unlikeable and hard to understand. It is not easy to get students who come to school with this prejudice to like the lesson and explain it. Our aim in this research is to eliminate this prejudice using right teaching methods and make mathematics a lesson attended voluntarily and with pleasure by the students. With this aim in mind, the effect of creative drama method on students’ success for the 6th grade mathematics lesson, area of triangles subject has been researched. This study has been applied on 100 students enrolled in two different state secondary schools in Aegean Region in 2017-2018 teaching term. In this study, classes are divided into two groups as control group and experimental group and a success test designed by researchers on area of triangles subject is applied to students as pretest and final test...

The purpose of this study was to investigate the relationship betvveen tenth grade students' ... more The purpose of this study was to investigate the relationship betvveen tenth grade students' learning styles and their geometric thinking levels. Participants were 79 students of tenth grade from an Anatolian high school in Balikesir. Kolb's Learning Style Inventory was used to determine their learning styles; and, a Geometric Thinking Levels Test consisting twenty-five, was administered to determine their geometric thinking levels. Results showed that students had assimilator and con-verger learning styles, and they were at level 2 (analysis) and level 3 (Informal deduction) in general, in order to determine the relation between their learning styles and geometric thinking levels, x2 test was conducted. No statistically sig-nificant relationship was found between tenth grade students' learning styles and their geometric thinking levels [x2 0.05]. These findings point out the fact that learning styles could not be considered as an effective contribu-tor to participants&#...

Bu calismada, yaratici dramanin matematik ogretiminde nasil kullanilacagi, ogrenme) nasil etkiled... more Bu calismada, yaratici dramanin matematik ogretiminde nasil kullanilacagi, ogrenme) nasil etkiledigi uzerinde durulmakta ve bir etkinlik ornegi verilmektedir. Matematik sevmeyen ve matematikten korkan, matematik kaygisi tasiyan ogrencilere yaratici dram kullanarak ogretim yapilmasi ve ogrenci uzerindeki etkilerinin neler olacagin deginilmektedir. Yaparak yasayarak ogrenme ogrencinin ogrendigi bilgilerin daha kali( olmasini saglar. Ogrenci etkin olacagindan sikilmaz ve dersler zevkli gecer. Yaratici dram ogrencinin sosyallesmesini saglar, dinlemeyi ve kendini ifade edebilme becerilerini, e onemlisi de yaraticiligini gelistirir. Bu da matematik dersi icin cok onemlidir.

European Journal of Education Studies, 2018

What our century requires is an individual, who can recognize and solve a problem, think in a cri... more What our century requires is an individual, who can recognize and solve a problem, think in a critical manner, are productive, responsible, and open to innovation, and are capable of cooperating with others. The requirements of our era are also reflected on education. Education systems change and improve accordingly; thereby new education systems are discussed. One of these education systems is STEM, which is an acronym of Science, Technology, Engineering and Mathematics. STEM is an educational approach, which integrates education with the application opportunities provided by technology and engineering that are based on the fields of science and mathematics and which includes all stages of education from pre-school to higher education. In this study, creative drama method and its applicability on STEM education process have been discussed. Problem solving, creating a problem, approaching a problem from different perspectives, and mathematical thinking skills, all of which are among...

Biotechnic & Histochemistry, 2020

ABSTRACT We investigated the distribution of connective tissue fibers in diabetic and vitamin C t... more ABSTRACT We investigated the distribution of connective tissue fibers in diabetic and vitamin C treated diabetic rat spleen. Rats were divided into three groups: group A, control; group B, diabetic; group C, vitamin C treated diabetic. Diabetes was induced by streptozotocin. Vitamin C was administered intragastrically for 21 days. Spleen tissues were examined by light microscopy after staining with Masson’s trichrome, Gomori silver impregnation and van Gieson. In group B, we found accumulation of collagen fibers in the trabeculae, in the capsule and around the central artery and splenic sinusoids. Splenic cord thickening due to fibrosis was observed. Reticular fibers accumulated principally in the white and red pulps of the spleen and focal reticular fiber thickening was observed in the dense fiber areas. Partial elastic fiber rupture was observed among the fibers of the elastic lamina of the arteries in the hilum. By contrast, the distribution of collagen fibers in group C was similar to group A. Collagen fiber accumulation was decreased in group C compared to group B. We found little reticular fiber thickening in group C and elastic fibers maintained their integrity and were better organized than in group B. Our findings suggest that appropriate doses of vitamin C may exert beneficial effects on the structure of the connective tissue fibers in the diabetic spleen.

Eğitimde Kuram ve Uygulama, 2018

Öz Makale Bilgisi Bu çalışmada sınıf öğretmenlerinin matematik dersi konularına ilişkin öz-yeterl... more Öz Makale Bilgisi Bu çalışmada sınıf öğretmenlerinin matematik dersi konularına ilişkin öz-yeterlik algılarının bazı değişkenler açısından incelenmesi amaçlanmıştır. Araştırma tarama modelinde betimsel bir çalışmadır. Çalışmanın örneklemini Artvin ve Aydın merkez ilçede çalışan 315 sınıf öğretmeni oluşturmaktadır. 2015-2016 eğitim öğretim yılında gerçekleştirilen çalışmada veri toplama aracı olarak anket uygulanmıştır. Araştırmaya katılan sınıf öğretmenlerinin matematik dersine ilişkin öz-yeterlik algılarını incelemek için elde edilen veri seti SPSS 22.0 paket programında analiz edilmiştir. Verilerin analizi kapsamında, frekans tabloları, güvenirlik ve geçerlilik analizi, Kaiser-Mayer-Olkin örneklem yeterliliği ölçütü, Bartlett sınaması, faktör analizi, bağımsız örneklem t testi, tek yönlü varyans analizi ve Tukey testinden faydalanmıştır. Araştırmada kadın sınıf öğretmenlerinin veri alanına ilişkin öz-yeterlik algı ortalaması erkek sınıf öğretmenlerine göre daha yüksek olduğu, öz-yeterlik algılarının yaşa ve mesleki kıdem süresine göre farklılık göstermediği, son iki yılda matematik içeriği etkinliğine katılan sınıf öğretmenlerinin geometri alanına ilişkin öz-yeterlik algı ortalamasının etkinliğe katılmayan sınıf öğretmenlerine göre daha yüksek olduğu, sınıf öğretmenliğinde teknoloji kullanımı etkinliğine katılan sınıf öğretmenlerinin geometri ve veri alanlarına ilişkin özyeterlik algı ortalamasının etkinliğe katılmayan sınıf öğretmenlerine göre daha yüksek olduğu, son iki yılda dersin değerlendirilmesi (ölçme) etkinliğine katılan sınıf öğretmenlerinin sayılar, geometri ve öz-yeterlik genel algı ortalaması etkinliğe katılmayan sınıf öğretmenlerine göre daha yüksek olduğu tespit edilmiştir. Elde edilen sonuçlar doğrultusunda, sınıf öğretmenlerinin üniversite yıllarında aldıkları Matematik ve Matematik Öğretimi derslerinin sayısı, içeriği ve haftalık ders sayısının artırılması önerisinde bulunulmuştur. Ayrıca sınıf öğretmenlerinin belirli aralıklarla katılacakları hizmet içi eğitim etkinliklerinin zorunlu hale getirilip, bu tür etkinliklerin içeriğinin çok dikkatli bir şekilde düzenlenip daha verimli hale getirilmesi önerisinde bulunulmuştur.

e-Journal of New World Sciences Academy, 2017

The purpose of this research is to identify the instructional methods used by special education t... more The purpose of this research is to identify the instructional methods used by special education teachers with a primary school teaching degree when teaching numbers to special education students. Qualitative case study was used as the research method. Research was conducted at a school accredited by the Ministry of Education, serving students with moderate and severe mental disability. Purposeful sampling was used. Data was collected via semi structured interviews and observations of three educators with a primary school teaching degree and were in a segregated special education classroom. Gathered data was analyzed using descriptive analysis. According to the results, when teaching the numbers unit, special education teachers with a primary school teaching degree mostly preferred direct instruction with some exceptions where they utilized graded method. Teachers did not have sufficient knowledge of instructional methods used in the special education field, therefore they often improvised with the information they were accustomed to use in a general education setting. Although teachers were able to develop individual education plans with ease, they were struggling to implement these plans efficiently in the classroom.

Journal of Education and Training Studies, 2017

The purpose of this study has been to determine the views of elementary mathematics teachers on t... more The purpose of this study has been to determine the views of elementary mathematics teachers on the applicability of modeling in mathematics courses. A case study was conducted with 17 elementary mathematics teachers working in various provinces in Turkey. An interview form consisting of open-ended questions was designed for the purpose of collecting data, which was obtained through semi-structured interviews. From the categories constituting the themes developed via the views of the teachers, four major conclusions and one minor conclusion were reached at the end of the study. Study results showed that the elementary mathematics teachers’ knowledge of the process and teaching performance had an impact on their views of the applicability of modeling.

Mathematical and Computational Applications, 2010

In this paper, a new approximate method for solving higher-order linear ordinary differential equ... more In this paper, a new approximate method for solving higher-order linear ordinary differential equations with variable coefficients under the mixed conditions is presented. The method is based on the rational Chebyshev (RC) Tau, Chebyshev and Taylor collocation methods. The solution is obtained in terms of rational Chebyshev (RC) functions. Also, illustrative examples are given to demonstrate the validity and applicability of the method.

Gazi Üniversitesi Gazi Eğitim Fakültesi Dergisi, Jun 1, 2004

In this study, it is explained why Concept Maps and Vee Diagrams, which are recent developments t... more In this study, it is explained why Concept Maps and Vee Diagrams, which are recent developments to help students produce meaningful learning and be active, are essential tools for teaching and how we can make and use Concept Maps and Vee Diagrams in mathematics education. Concept Map and Vee Diagrams, which were made for the unit of functions, are presented.

Cytotechnology, 2014

Carbon tetrachloride (CCl 4) is widely used to induce liver toxicity in in vitro/in vivo models. ... more Carbon tetrachloride (CCl 4) is widely used to induce liver toxicity in in vitro/in vivo models. Lipid peroxidation (LPO) begins with toxicity and affects cell viability. Recently, the beneficial effects of melatonin and Vitamin D on cell proliferation in human normal and cancer cells were found. This study was planned to evaluate antioxidant and cytoprotective activity of melatonin and Vitamin D in CCl 4 induced cytotoxicity in HepG2 and Hep3B hepatoma cell lines. Based on the cytotoxicity assay, melatonin and Vitamin D were evaluated for cytotoprotective potential against CCl 4 induced toxicity in HepG2 and Hep3B liver cell lines by monitoring cell viability, LPO and glutathione (GSH) level. Different dosages of CCl 4 (0.1, 0.2, 0.3 and 0.4 % v/v) were applied to HepG2 and Hep3B cells in order to determine the most toxic dosage of it in a time dependent manner. The same experiments were repeated with exogenously applied melatonin (MEL) and Vitamin D to groups treated with/without CCL 4. Cell viability was determined with MTT measurements at the 2nd, 24th and 48th h. GSH content and Malondialdehyde levels were measured from the cell lysates. As a result, both melatonin and Vitamin D administration during CCl 4 exposure protected liver cells from CCl 4 induced cell damage. Increase in LPO and decrease in GSH were found in the CCl 4 groups of both cells. Contrary to these results administration of MEL and Vitamin D on cells exhibited results similar to the control groups. Therefore, melatonin and Vitamin D might be a promising therapeutic agent in several toxic hepatic diseases.

International Journal of E-Adoption, 2011

This study examines the use of Moodle assisted online collaboration environment in a Special Teac... more This study examines the use of Moodle assisted online collaboration environment in a Special Teaching Techniques class. In this paper, the authors investigate the effect of Moodle assisted online collaboration on prospective secondary mathematics teachers’ attitudes toward the use of the Internet and evaluate the prospective teachers’ opinions regarding the process. The method of this study is one grouped pre-test post-test model. The 30 participants of secondary mathematics education without thesis program are the study group of this research. The special mathematics teaching techniques class supported lessons with the help of the Moodle environment for 9 weeks. After the process, no significant difference existed in the attitudes of the prospective mathematics teachers toward Internet usage. However, according to the interviews, the teachers said they found the process advantageous and favorable and want further implementations in other classes.

ab.org.tr

Özet: Uzaktan eğitim yıllardır uygulanmaktadır. Yıllar boyunca uzaktan eğitimin uygulanma biçimi ... more Özet: Uzaktan eğitim yıllardır uygulanmaktadır. Yıllar boyunca uzaktan eğitimin uygulanma biçimi teknolojinin gelişmesiyle birlikte farklılıklar göstermiştir. Bu farklılıklar öğrenmeyi en üst düzeye çıkarabilmek için yapılmış ve günümüzdeki haline kavuşmuştur. Bugünün ...

Cell Biochemistry and Function, 2005

The morphological changes of gingival mast cells of alloxan-induced diabetic rats were studied by... more The morphological changes of gingival mast cells of alloxan-induced diabetic rats were studied by electron microscopy. The following observations were made. The cell nucleus and cytoplasm degenerated. The electron density of the granules in the cell cytoplasm clearly decreased. Some granules had dense irregular threads and the granules were surrounded by a thin vacuole. A ghost vacuole formed in some mast cells and disorganized materials accumulated in the cytoplasm. The mast cell nuclei were generally irregular and degenerating mast cells had pyknotic nuclei. General destruction of the cell membrane and granule shedding in some samples was noted and mitochondria with atypical cristae in the cytoplasm of the mast cells were seen. We conclude that the characteristics of the ultrastructure of gingival mast cells in diabetics are distinctive and should be used as criteria for pathogenesis of gingival inflammation. Copyright # 2004 John Wiley & Sons, Ltd. key words-diabetes mellitus (alloxan-induced); Wistar albino rat; gingiva; mast cell; ultrastructure

Cell Biochemistry and Function, 2006

Patulin is a mycotoxin that is produced by species of Penicillum, Aspergillus, and Byssochylamys ... more Patulin is a mycotoxin that is produced by species of Penicillum, Aspergillus, and Byssochylamys molds that may grow on a variety of foods including fruit, grains and cheese. Patulin, at a dose of 0.1 mg kg À1 bw day À1 was administered orally to growing male rats aged 5-6 weeks for a period of 60 or 90 days. The dose of patulin used in the present study was based on estimated human exposure levels. At the end of these periods, the thymus glands of patulin-treated and control Wistar rats were removed and ultrastructural changes in capillary cells of the thymus of patulin-treated Wistar rats were determined by electron microscopy. The walls of thymus capillaries of the 60-day patulin-treated rat groups (P-60) exhibited degeneration observable in electron microscopic sections. For example, loss of cytoplasm and mitochondrial cristae of cells, swollen endothelial cells, increased thickness of the basement membrane, closed lumen of capillaries, accumulation of fibrous material at the periphery of the capillaries and nuclear anomalies were seen in these sections. Such degeneration and changes were also observed in sections of capillaries of the 90-day patulin-treated rat groups (P-90). The levels of degeneration of endothelial cell nucleus of P-90 were greater than those of P-60. This study demonstrated the ultrastructural degeneration of thymus capillary cells of patulin-treated rats. The results obtained from this study may provide a guide to research dealing with the toxic effects of patulin on tissue and organ ultrastructure.

Bu calismada periodontitisli hastalarda diseti dokusundaki notrofil lokositler incelenmistir. Biy... more Bu calismada periodontitisli hastalarda diseti dokusundaki notrofil lokositler incelenmistir. Biyopsi materyalleri yetiskin periodontitisli uc hastadan ameliyat aninda elde edilmistir. Doku biyopsilerinden hazirlanan kesitler isik ve elektron mikroskobunda incelenmistir. Iltihaplanmamis disetlerinde oral epitelin normal yapisini korudugu gozlenmistir. Bazi dejeneratif olusumlar iltihapli diseti epiteli ve bag dokusunda gorulmustur. Sulkular epitelde parakeratotik gorunus, bol miktarda rete peg yapilari, epitel alti iltihabi hucre infiltrasyonu gozlenmistir. Cep epitelinde rete peg yapilari, genislemis interseluler araliklar, interseluler koprulerin sayisinda azalma, iltihabi hucre infiltrasyonunda artis gibi bazi yapisal degisiklikler saptanmistir. Polimorfonukleer lokositler epitelin genis interseluler araliklarindaki kadar cep epiteli ve cep epiteline yakin damarlar icerisinde nadiren gozlenmistir. Epitel alti bag doku lezyonlarinda fibroblastlar, makrofajlar, mast hucreleri, lenfositler, plazma hucreleri ve az sayida polimorfonukleer lokositler gozlenmistir. Bundan baska elektron mikrograflannda plak mikroorganizmalarini fagosite eden polimorfonukleer lokositler ve doku artiklari arasinda makrofaj pseudopodlari teshis edilmistir. Abstract In this study, neutrophil leuckocytes within the gingival tissue in periodonti tis patients were examined. Biopsy materials were obtained from three adult perio dontitis patient during the operation. The sections prepared from tissue biopsies were studied by light and electron microscopy. It is observed that oral epithelium maintains it's normal structure in uninflammed gingiva. Some degenerative formations have appeared in inflamed gingival epithelium and connective tissue. Parakeratotic aspect, many rete peg formations and subepithelial inflammatory cells infiltrations were observed in the sulcular epithelium. In the pocket epithelium some structural altera tions as rete peg formations, enlargements of intercellular spaces, a decreased number of intercellular bridges and increased infiltration of inflammatory cells, have been determined. Polymorphonuclear leukocytes were rarely observed within the pocket epithelium and it's adjacent vessels, as well as, wide intercellular spaces of the epithelium. In the subepithelial connective tissue lesions, fibroblast, macrophages, mast cells, lymphocytes, plasma cells and few polymorphonuclear leukocytes were observed. Furthermore in electron micrographs, the polymorphonuclear leukocytes that phagocytized the plaque microorganisms and the pseudopodia of macrophages through tissue debris were determined.

Pharmacological Research, 2003

The effects of chronic alcohol consumption on myocardial ischemia and gas perfusion with 95% O 2-... more The effects of chronic alcohol consumption on myocardial ischemia and gas perfusion with 95% O 2-5% CO 2 were investigated in isolated rat heart. Eighteen adult male Wistar rats were used. Rats were assigned into six groups for each group to contain three rats: normal, alcoholic, normal ischemic, alcoholic ischemic, normal ischemic and 95% O 2-5% CO 2 perfused, alcoholic ischemic and 95% O 2-5% CO 2 perfused, respectively. Alcohol (7.2%, v/v) was given to rats by a modified liquid diet for 21 days. Rats were anaesthetized with ketamine (1-2 mg kg −1). Hearts were quickly isolated. Normal and alcoholic rat hearts were directly sent to the electron microscopic preparation. The other hearts were cut into small pieces and put into Krebs solution. The solution was continuously bubbled using 95% N 2-5% CO 2 20 min for ischemia. After removal of normal ischemic and alcoholic ischemic heart specimens for electron microscopic examination, the remaining hearts of the last two groups were bubbled with 95% O 2-5% CO 2 for another 20 min for the purpose of reperfusion and then were also prepared for electron microscopic examination. The hearts were investigated with a transmission electron microscope (Jeol 100 CXII TEM). Twenty-one days of chronic alcohol consumption was found to have no significant effect on myocardial ischemia determined by transmission electron microscopic examination. Our results suggest that there is no significant relationship between 21 days of alcohol consumption by a liquid diet and myocardial protection.

"Values Education", which added to Mathematics Teaching Program at the Turkish Academic Year of 2... more "Values Education", which added to Mathematics Teaching Program at the Turkish Academic Year of 2017-2018, is revised and updated as "Our Values" on January of 2018. "Our Values" based on a grown value system that aims to maintain the existence of societies preserve the unity and togetherness of societies and have the real educational success like every stage of individuals' life. The Ministry of National Education has determined the base values, which should be gained during the education of Mathematics, as justice, friendship, honesty, patience, respect, love, responsibility, patriotism and helpfulness. The aim of this study is making the students realize their own values and making them gain the helpfulness values by using creative drama activities during the education of Mathematics. In this study, "helpfulness value", which is under the topic of "Our Values" of Mathematics Teaching Program, was tried to put into practise by creative drama activities. In the study, experimental method which contains pretested and postested control group is used in order to show the behaviour difference between experimental group, which activity based creative drama method was applied, and the control group, which activity based creative drama method was not applied. This study is designed as a controlled experimental study with pretest-posttest. The group of study was consisted 106 students, which studying in 3 different provinces (Aydın, Afyon, Uşak) in the same region. Both experimental and control group was consisted by 53 students. In the study, data were collected from "helpfulness scale" which developed by Demirci (2017). As a result of the study, the helpfulness scale score of experimental group, which activity based creative drama was

The purpose of this study is to determine the effect of learning together technique of cooperativ... more The purpose of this study is to determine the effect of learning together technique of cooperative learning method on student’ mathematics achievement. The study was an experimental research in which pre-test – post-test design with control group was applied. The study was conducted in spring 2004 with 70 pupils

European Journal of Education Studies, 2018

Geometry holds an important place in the developmental process of mathematical thinking. When geo... more Geometry holds an important place in the developmental process of mathematical thinking. When geometry is the subject in mathematics lessons, it is seen by students as an unlikeable and hard to understand. It is not easy to get students who come to school with this prejudice to like the lesson and explain it. Our aim in this research is to eliminate this prejudice using right teaching methods and make mathematics a lesson attended voluntarily and with pleasure by the students. With this aim in mind, the effect of creative drama method on students’ success for the 6th grade mathematics lesson, area of triangles subject has been researched. This study has been applied on 100 students enrolled in two different state secondary schools in Aegean Region in 2017-2018 teaching term. In this study, classes are divided into two groups as control group and experimental group and a success test designed by researchers on area of triangles subject is applied to students as pretest and final test...

The purpose of this study was to investigate the relationship betvveen tenth grade students' ... more The purpose of this study was to investigate the relationship betvveen tenth grade students' learning styles and their geometric thinking levels. Participants were 79 students of tenth grade from an Anatolian high school in Balikesir. Kolb's Learning Style Inventory was used to determine their learning styles; and, a Geometric Thinking Levels Test consisting twenty-five, was administered to determine their geometric thinking levels. Results showed that students had assimilator and con-verger learning styles, and they were at level 2 (analysis) and level 3 (Informal deduction) in general, in order to determine the relation between their learning styles and geometric thinking levels, x2 test was conducted. No statistically sig-nificant relationship was found between tenth grade students' learning styles and their geometric thinking levels [x2 0.05]. These findings point out the fact that learning styles could not be considered as an effective contribu-tor to participants&#...

Bu calismada, yaratici dramanin matematik ogretiminde nasil kullanilacagi, ogrenme) nasil etkiled... more Bu calismada, yaratici dramanin matematik ogretiminde nasil kullanilacagi, ogrenme) nasil etkiledigi uzerinde durulmakta ve bir etkinlik ornegi verilmektedir. Matematik sevmeyen ve matematikten korkan, matematik kaygisi tasiyan ogrencilere yaratici dram kullanarak ogretim yapilmasi ve ogrenci uzerindeki etkilerinin neler olacagin deginilmektedir. Yaparak yasayarak ogrenme ogrencinin ogrendigi bilgilerin daha kali( olmasini saglar. Ogrenci etkin olacagindan sikilmaz ve dersler zevkli gecer. Yaratici dram ogrencinin sosyallesmesini saglar, dinlemeyi ve kendini ifade edebilme becerilerini, e onemlisi de yaraticiligini gelistirir. Bu da matematik dersi icin cok onemlidir.

European Journal of Education Studies, 2018

What our century requires is an individual, who can recognize and solve a problem, think in a cri... more What our century requires is an individual, who can recognize and solve a problem, think in a critical manner, are productive, responsible, and open to innovation, and are capable of cooperating with others. The requirements of our era are also reflected on education. Education systems change and improve accordingly; thereby new education systems are discussed. One of these education systems is STEM, which is an acronym of Science, Technology, Engineering and Mathematics. STEM is an educational approach, which integrates education with the application opportunities provided by technology and engineering that are based on the fields of science and mathematics and which includes all stages of education from pre-school to higher education. In this study, creative drama method and its applicability on STEM education process have been discussed. Problem solving, creating a problem, approaching a problem from different perspectives, and mathematical thinking skills, all of which are among...

Biotechnic & Histochemistry, 2020

ABSTRACT We investigated the distribution of connective tissue fibers in diabetic and vitamin C t... more ABSTRACT We investigated the distribution of connective tissue fibers in diabetic and vitamin C treated diabetic rat spleen. Rats were divided into three groups: group A, control; group B, diabetic; group C, vitamin C treated diabetic. Diabetes was induced by streptozotocin. Vitamin C was administered intragastrically for 21 days. Spleen tissues were examined by light microscopy after staining with Masson’s trichrome, Gomori silver impregnation and van Gieson. In group B, we found accumulation of collagen fibers in the trabeculae, in the capsule and around the central artery and splenic sinusoids. Splenic cord thickening due to fibrosis was observed. Reticular fibers accumulated principally in the white and red pulps of the spleen and focal reticular fiber thickening was observed in the dense fiber areas. Partial elastic fiber rupture was observed among the fibers of the elastic lamina of the arteries in the hilum. By contrast, the distribution of collagen fibers in group C was similar to group A. Collagen fiber accumulation was decreased in group C compared to group B. We found little reticular fiber thickening in group C and elastic fibers maintained their integrity and were better organized than in group B. Our findings suggest that appropriate doses of vitamin C may exert beneficial effects on the structure of the connective tissue fibers in the diabetic spleen.

Eğitimde Kuram ve Uygulama, 2018

Öz Makale Bilgisi Bu çalışmada sınıf öğretmenlerinin matematik dersi konularına ilişkin öz-yeterl... more Öz Makale Bilgisi Bu çalışmada sınıf öğretmenlerinin matematik dersi konularına ilişkin öz-yeterlik algılarının bazı değişkenler açısından incelenmesi amaçlanmıştır. Araştırma tarama modelinde betimsel bir çalışmadır. Çalışmanın örneklemini Artvin ve Aydın merkez ilçede çalışan 315 sınıf öğretmeni oluşturmaktadır. 2015-2016 eğitim öğretim yılında gerçekleştirilen çalışmada veri toplama aracı olarak anket uygulanmıştır. Araştırmaya katılan sınıf öğretmenlerinin matematik dersine ilişkin öz-yeterlik algılarını incelemek için elde edilen veri seti SPSS 22.0 paket programında analiz edilmiştir. Verilerin analizi kapsamında, frekans tabloları, güvenirlik ve geçerlilik analizi, Kaiser-Mayer-Olkin örneklem yeterliliği ölçütü, Bartlett sınaması, faktör analizi, bağımsız örneklem t testi, tek yönlü varyans analizi ve Tukey testinden faydalanmıştır. Araştırmada kadın sınıf öğretmenlerinin veri alanına ilişkin öz-yeterlik algı ortalaması erkek sınıf öğretmenlerine göre daha yüksek olduğu, öz-yeterlik algılarının yaşa ve mesleki kıdem süresine göre farklılık göstermediği, son iki yılda matematik içeriği etkinliğine katılan sınıf öğretmenlerinin geometri alanına ilişkin öz-yeterlik algı ortalamasının etkinliğe katılmayan sınıf öğretmenlerine göre daha yüksek olduğu, sınıf öğretmenliğinde teknoloji kullanımı etkinliğine katılan sınıf öğretmenlerinin geometri ve veri alanlarına ilişkin özyeterlik algı ortalamasının etkinliğe katılmayan sınıf öğretmenlerine göre daha yüksek olduğu, son iki yılda dersin değerlendirilmesi (ölçme) etkinliğine katılan sınıf öğretmenlerinin sayılar, geometri ve öz-yeterlik genel algı ortalaması etkinliğe katılmayan sınıf öğretmenlerine göre daha yüksek olduğu tespit edilmiştir. Elde edilen sonuçlar doğrultusunda, sınıf öğretmenlerinin üniversite yıllarında aldıkları Matematik ve Matematik Öğretimi derslerinin sayısı, içeriği ve haftalık ders sayısının artırılması önerisinde bulunulmuştur. Ayrıca sınıf öğretmenlerinin belirli aralıklarla katılacakları hizmet içi eğitim etkinliklerinin zorunlu hale getirilip, bu tür etkinliklerin içeriğinin çok dikkatli bir şekilde düzenlenip daha verimli hale getirilmesi önerisinde bulunulmuştur.

e-Journal of New World Sciences Academy, 2017

The purpose of this research is to identify the instructional methods used by special education t... more The purpose of this research is to identify the instructional methods used by special education teachers with a primary school teaching degree when teaching numbers to special education students. Qualitative case study was used as the research method. Research was conducted at a school accredited by the Ministry of Education, serving students with moderate and severe mental disability. Purposeful sampling was used. Data was collected via semi structured interviews and observations of three educators with a primary school teaching degree and were in a segregated special education classroom. Gathered data was analyzed using descriptive analysis. According to the results, when teaching the numbers unit, special education teachers with a primary school teaching degree mostly preferred direct instruction with some exceptions where they utilized graded method. Teachers did not have sufficient knowledge of instructional methods used in the special education field, therefore they often improvised with the information they were accustomed to use in a general education setting. Although teachers were able to develop individual education plans with ease, they were struggling to implement these plans efficiently in the classroom.

Journal of Education and Training Studies, 2017

The purpose of this study has been to determine the views of elementary mathematics teachers on t... more The purpose of this study has been to determine the views of elementary mathematics teachers on the applicability of modeling in mathematics courses. A case study was conducted with 17 elementary mathematics teachers working in various provinces in Turkey. An interview form consisting of open-ended questions was designed for the purpose of collecting data, which was obtained through semi-structured interviews. From the categories constituting the themes developed via the views of the teachers, four major conclusions and one minor conclusion were reached at the end of the study. Study results showed that the elementary mathematics teachers’ knowledge of the process and teaching performance had an impact on their views of the applicability of modeling.

Mathematical and Computational Applications, 2010

In this paper, a new approximate method for solving higher-order linear ordinary differential equ... more In this paper, a new approximate method for solving higher-order linear ordinary differential equations with variable coefficients under the mixed conditions is presented. The method is based on the rational Chebyshev (RC) Tau, Chebyshev and Taylor collocation methods. The solution is obtained in terms of rational Chebyshev (RC) functions. Also, illustrative examples are given to demonstrate the validity and applicability of the method.

Gazi Üniversitesi Gazi Eğitim Fakültesi Dergisi, Jun 1, 2004

In this study, it is explained why Concept Maps and Vee Diagrams, which are recent developments t... more In this study, it is explained why Concept Maps and Vee Diagrams, which are recent developments to help students produce meaningful learning and be active, are essential tools for teaching and how we can make and use Concept Maps and Vee Diagrams in mathematics education. Concept Map and Vee Diagrams, which were made for the unit of functions, are presented.

Cytotechnology, 2014

Carbon tetrachloride (CCl 4) is widely used to induce liver toxicity in in vitro/in vivo models. ... more Carbon tetrachloride (CCl 4) is widely used to induce liver toxicity in in vitro/in vivo models. Lipid peroxidation (LPO) begins with toxicity and affects cell viability. Recently, the beneficial effects of melatonin and Vitamin D on cell proliferation in human normal and cancer cells were found. This study was planned to evaluate antioxidant and cytoprotective activity of melatonin and Vitamin D in CCl 4 induced cytotoxicity in HepG2 and Hep3B hepatoma cell lines. Based on the cytotoxicity assay, melatonin and Vitamin D were evaluated for cytotoprotective potential against CCl 4 induced toxicity in HepG2 and Hep3B liver cell lines by monitoring cell viability, LPO and glutathione (GSH) level. Different dosages of CCl 4 (0.1, 0.2, 0.3 and 0.4 % v/v) were applied to HepG2 and Hep3B cells in order to determine the most toxic dosage of it in a time dependent manner. The same experiments were repeated with exogenously applied melatonin (MEL) and Vitamin D to groups treated with/without CCL 4. Cell viability was determined with MTT measurements at the 2nd, 24th and 48th h. GSH content and Malondialdehyde levels were measured from the cell lysates. As a result, both melatonin and Vitamin D administration during CCl 4 exposure protected liver cells from CCl 4 induced cell damage. Increase in LPO and decrease in GSH were found in the CCl 4 groups of both cells. Contrary to these results administration of MEL and Vitamin D on cells exhibited results similar to the control groups. Therefore, melatonin and Vitamin D might be a promising therapeutic agent in several toxic hepatic diseases.

International Journal of E-Adoption, 2011

This study examines the use of Moodle assisted online collaboration environment in a Special Teac... more This study examines the use of Moodle assisted online collaboration environment in a Special Teaching Techniques class. In this paper, the authors investigate the effect of Moodle assisted online collaboration on prospective secondary mathematics teachers’ attitudes toward the use of the Internet and evaluate the prospective teachers’ opinions regarding the process. The method of this study is one grouped pre-test post-test model. The 30 participants of secondary mathematics education without thesis program are the study group of this research. The special mathematics teaching techniques class supported lessons with the help of the Moodle environment for 9 weeks. After the process, no significant difference existed in the attitudes of the prospective mathematics teachers toward Internet usage. However, according to the interviews, the teachers said they found the process advantageous and favorable and want further implementations in other classes.

ab.org.tr

Özet: Uzaktan eğitim yıllardır uygulanmaktadır. Yıllar boyunca uzaktan eğitimin uygulanma biçimi ... more Özet: Uzaktan eğitim yıllardır uygulanmaktadır. Yıllar boyunca uzaktan eğitimin uygulanma biçimi teknolojinin gelişmesiyle birlikte farklılıklar göstermiştir. Bu farklılıklar öğrenmeyi en üst düzeye çıkarabilmek için yapılmış ve günümüzdeki haline kavuşmuştur. Bugünün ...

Cell Biochemistry and Function, 2005

The morphological changes of gingival mast cells of alloxan-induced diabetic rats were studied by... more The morphological changes of gingival mast cells of alloxan-induced diabetic rats were studied by electron microscopy. The following observations were made. The cell nucleus and cytoplasm degenerated. The electron density of the granules in the cell cytoplasm clearly decreased. Some granules had dense irregular threads and the granules were surrounded by a thin vacuole. A ghost vacuole formed in some mast cells and disorganized materials accumulated in the cytoplasm. The mast cell nuclei were generally irregular and degenerating mast cells had pyknotic nuclei. General destruction of the cell membrane and granule shedding in some samples was noted and mitochondria with atypical cristae in the cytoplasm of the mast cells were seen. We conclude that the characteristics of the ultrastructure of gingival mast cells in diabetics are distinctive and should be used as criteria for pathogenesis of gingival inflammation. Copyright # 2004 John Wiley & Sons, Ltd. key words-diabetes mellitus (alloxan-induced); Wistar albino rat; gingiva; mast cell; ultrastructure

Cell Biochemistry and Function, 2006

Patulin is a mycotoxin that is produced by species of Penicillum, Aspergillus, and Byssochylamys ... more Patulin is a mycotoxin that is produced by species of Penicillum, Aspergillus, and Byssochylamys molds that may grow on a variety of foods including fruit, grains and cheese. Patulin, at a dose of 0.1 mg kg À1 bw day À1 was administered orally to growing male rats aged 5-6 weeks for a period of 60 or 90 days. The dose of patulin used in the present study was based on estimated human exposure levels. At the end of these periods, the thymus glands of patulin-treated and control Wistar rats were removed and ultrastructural changes in capillary cells of the thymus of patulin-treated Wistar rats were determined by electron microscopy. The walls of thymus capillaries of the 60-day patulin-treated rat groups (P-60) exhibited degeneration observable in electron microscopic sections. For example, loss of cytoplasm and mitochondrial cristae of cells, swollen endothelial cells, increased thickness of the basement membrane, closed lumen of capillaries, accumulation of fibrous material at the periphery of the capillaries and nuclear anomalies were seen in these sections. Such degeneration and changes were also observed in sections of capillaries of the 90-day patulin-treated rat groups (P-90). The levels of degeneration of endothelial cell nucleus of P-90 were greater than those of P-60. This study demonstrated the ultrastructural degeneration of thymus capillary cells of patulin-treated rats. The results obtained from this study may provide a guide to research dealing with the toxic effects of patulin on tissue and organ ultrastructure.