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Papers by pritipadma panda

Arabian Journal of Chemistry, 2015

The antibacterial activity of peppermint oil and different extracts of Mentha piperita against so... more The antibacterial activity of peppermint oil and different extracts of Mentha piperita against some Gram-positive and Gram-negative bacterial strains was evaluated in the present research work by agar well diffusion method. It was found that the distilled concentrations of essential oil inhibited the growth of microorganisms and the results were comparable with those of antibiotic gentamycin. Essential oils showed a wider spectrum of activity but less strong inhibition as compared to the investigated commercial antibiotic. Minimum inhibitory concentrations (MICs) for the bacterial species ranged from 0.4% to 0.7% v/v. The oil and extracts also exhibited significant antioxidant activity and the oil showed about half potency when compared to the standard BHT. These results indicated the strong antibacterial and antioxidant activities of peppermint oil but additional investigations need to be performed in order to confirm the safety of these concentrations (MIC) for human consumption. Peppermint oil could be used as a good conservation agent by inhibiting some food borne pathogens.

International Journal of Experimental Research and Review

Vitamin A and its derivatives, also known as retinoids, when applied topically for anti-ageing be... more Vitamin A and its derivatives, also known as retinoids, when applied topically for anti-ageing benefits, typically cause erythema and dryness on the skin, which are considered significant and common side effects. Furthermore, users of topical retinoids, like everyone else, need a sunscreen that protects the skin from harmful sun exposure while simultaneously countering the erythema and dryness of the skin. Retinoids also enhance the rate of skin cell turnover and expose newly produced skin to solar exposure, increasing the risk of sun damage and hyperpigmentation. Since the skin becomes sensitive with topical retinoids, a sunscreen must possess the further benefit of elevated skin resilience, which is much needed with conventional sun protection. ‘‘EI Pro Retinol Sunscreen’’ came up with a new innovative sunscreen with UV protectants and other active ingredients that have calming and soothing properties that minimize erythema and dryness. EI launched the “EI PRO Retinol series,” whi...

Pharmacognosy Research, 2014

Background: The presence of phytochemical constitutes has been reported from species of the Compo... more Background: The presence of phytochemical constitutes has been reported from species of the Compositae (Asteraceae). Hitherto no reports exist on the phytochemical components and biological activity of Lactuca runcinata DC. Objective: The present study was designed to determine the bioactive compounds in the whole plant methanol extract of Lactuca runcinata. Materials and Methods: Phytochemical screening of the entire herb of Lactuca runcinata DC revealed the presence of some bio-active components. Gas chromatography-mass spectrometry (GC-MS) analysis of the whole plant methanol extract of Lactuca runcinata was performed on a GC-MS equipment (Thermo Scientifi c Co.) Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II. Results: The phytochemical tests showed the presence of alkaloids, cardiac glycosides, fl avonoids, phenols, phlobatannin, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, and protein/amino acids in methanolic extract of L. runcinata. The GC-MS analysis has shown the presence of different phytochemical compounds in the methanolic extract of Lactuca runcinata. A total of 21 compounds were identifi ed representing 84.49% of total methanolic extract composition. Conclusion: From the results, it is evident that Lactuca runcinata contains various phytocomponents and is recommended as a plant of phytopharmaceutical importance.

International Journal of Applied Pharmaceutics, Jul 7, 2022

Iranian Journal of Science and Technology, Transactions A: Science, 2017

In the present study, a modified Osborne fractionation method was followed to isolate albumins, g... more In the present study, a modified Osborne fractionation method was followed to isolate albumins, globulins, prolamins and glutelins successively from seeds of Lagenaria siceraria. This research work was undertaken to determine amino acid content, molecular weight distribution and antioxidant potential of isolated protein fractions of L. siceraria seed. The antioxidant activity of the protein fractions was evaluated using DPPH, ABTS, nitric oxide radical scavenging, hydrogen peroxide scavenging, lipid peroxidation, reducing power and phosphomolybdate assays. The molecular weights of these fractions were in the range of 10-260 kDa. Globulin contains highest amount of hydrophobic amino acid (138.1 mg/gm) as well as essential amino acid (165.6 mg/g) as compared to other fractions. This resulted in highest antioxidant activity with nutritional values. The percentage of inhibition of the protein fractions differs significantly from each other (p B 0.05). The results indicate that the protein fractions of L. siceraria may be helpful in the therapy of various oxidative-stress-induced diseases and development of novel nutritional food supplements.

Iranian Journal of Science and Technology, Transactions A: Science, 2018

Bauhinia racemosa Lamk. and Bauhinia tomentosa linn. (Ceasalpiniaceae) leaves are used as holisti... more Bauhinia racemosa Lamk. and Bauhinia tomentosa linn. (Ceasalpiniaceae) leaves are used as holistic medicines mainly for inflammations and various skin disorders by the tribal sovereignty in Odisha ecoregion. This research work presents a study on chemical composition and tyrosinase inhibitory property of the methanol extract of leaves of Bauhinia racemosa (MBR) and Bauhinia tomentosa (MBT) with computational approaches. GC-MS technique, in-silico approach and in vitro tyrosinase inhibitory assay models were used for analysis of skin-whitening efficacies of these plant extracts. The major chemotype of the MBR was found to be myo-Inositol 4-C-methyl-(14.50%), whereas 3-O-Methyl-D-glucose (91.89%) was present in MBT as major compound. Tyrosinase inhibition was investigated against monophenolase (L-tyrosine). IC 50 values of MBR and MBT were found to be 280 ± 0.9 and 610 ± 1.7 lg/mL, respectively. Molecular docking analysis of the binding of myo-Inositol, 4-C-methyl-and 3-O-Methyl-D-glucose with protein (PDB ID: 1wx2) showed an extensive hydrogen bond network with amino acid residues like ASN 191, ALA 202 and SER 206, THR 203, ASN 191, respectively. Both these compounds showed good binding affinities with target receptors and can be used as lead molecules for inhibition of tyrosinase. MBR and MBT might be suggested as a better source of skin-whitening agents for cosmetic and medicinal applications.

Natural product research, Jan 16, 2017

The present study is the first effort to a comprehensive evaluation of antityrosinase activity an... more The present study is the first effort to a comprehensive evaluation of antityrosinase activity and chemometric analysis of Bauhinia vahlii. The experimental results revealed that the methanol extract of Bauhinia vahlii (BVM) possesses higher polyphenolic compounds and total antioxidant activity than those reported elsewhere for other more conventionally and geographically different varieties. The BVM contain saturated fatty acids such as hexadecanoic acid (10.15%), octadecanoic acid (1.97%), oleic acid (0.61%) and cis-vaccenic acid (2.43%) along with vitamin E (12.71%), α-amyrin (9.84%), methyl salicylate (2.39%) and β-sitosterol (17.35%), which were mainly responsible for antioxidant as well as tyrosinase inhibitory activity. Tyrosinase inhibitory activity of this extract was comparable to that of Kojic acid. These findings suggested that the B. vahlii leaves could be exploited as potential source of natural antioxidant and tyrosinase inhibitory agent, as well.

Indian Journal of Natural Products and Resources

Bauhinia vahlii has been reported for several medicinal properties, such as tyrosinase inhibitory... more Bauhinia vahlii has been reported for several medicinal properties, such as tyrosinase inhibitory, immunomodulatory and free radical scavenging activities. Bauhinia tomentosa and Bauhinia racemosa also possess anti-diabetic, anticancer, antidiabetic, anti-obesity and antihyperlipidemic activities. Therefore, the correct identification of these plants is critically important. The aim was to investigate the comparative morpho-micrometric analysis of 3 species of Bauhinia belonging to the family Leguminosae (Fabaceae) by using conventional as well as scanning electron microscopy to support species identification. In B. racemosa, epidermal cells are polygonal with anticlinical walls; whereas wavy walled cells are found in B. tomentosa and B. vahlii. Anisocytic stomata are present in B. racemosa, while B. tomentosa shows the presence of paracytic stomata and anomocytic stomata in B. vahlii. Stomatal numbers and stomatal indices were found to be more in B. vahlii than B. tomentosa and B. racemosa. On the other hand, uniseriate, unicellular covering trichomes are found in B. racemosa and B. tomentosa but B. vahlii contains only uniseriate, multicellular covering trichomes. Based on these micromorphological features, a diagnostic key was developed for identification of the particular species which helps a lot in pharmaceutical botany, taxonomy and horticulture, in terms of species identification.

This review is aimed at the integration of traditional ethno-medicinal knowledge and modern scien... more This review is aimed at the integration of traditional ethno-medicinal knowledge and modern scientific findings about Bauhinia racemosa in order to have understanding of its important therapeutic potential. It may attract the attention of natural product researchers throughout the world to focus on the unexplored potential of Bauhinia racemosa. More than 200 species of flowering plants are available under the genus Bauhinia, of which racemosa is one, which is known as ‘Sonpatta Tree’ as it is being considered to be as valuable as gold for its medicinal values. It is a small, crooked, bushy, deciduous tree with drooping branches and can grow in poor and very harsh climatic conditions. The tree is staggeringly beautiful when in bloom and it blooms for several months with flowers found in shades of magenta, lavender, purplish blue or even white. Almost each and every part of the plant possesses medicinal values. The bark and leaves of B. racemosa are sweetish and acrid, refrigerant, as...