atul pandey - Academia.edu (original) (raw)

Papers by atul pandey

Research paper thumbnail of REM sleep deprivation of rats induces acute phase response in liver

Biochemical and biophysical research …, Jan 1, 2011

REM sleep is essential for maintenance of body physiology and its deprivation is fatal. We observ... more REM sleep is essential for maintenance of body physiology and its deprivation is fatal. We observed that the levels of ALT and AST enzymes and pro-inflammatory cytokines like IL-1β, IL-6 and IL-12 circulating in the blood of REM sleep deprived rats increased in proportion to the extent of sleep loss. But in contrast the levels of IFN-γ and a ∼200 kDa protein, identified by N-terminal sequencing to be alpha-1-inhibitor-3(A1I3), decreased significantly. Quantitative PCR analysis confirmed that REM sleep deprivation down regulates AII3 gene and up regulates IL1 β, IL6 and their respective receptors gene expression in the liver initiating its inflammation.► Concentration of A1I3, an acute phase response protein circulating in the serum decreased proportionately to the REM sleep loss. ► The level of ALT and AST in the serum increased proportionate to the extent of REM sleep loss. ► Pro-Inflammatory cytokines like IL-1β, IL-6, and IL-12 & IFN γ in the blood were found to be modulated. ► REM sleep deprivation up regulated IL-1 β, IL-1 β r, and IL-6, IL-6r genes expression in the liver.

Research paper thumbnail of An energy-efficient multi-layer MAC (ML-MAC) protocol for wireless sensor networks

AEU-International Journal of …, Jan 1, 2011

The efficient use of energy is an important performance target to prolong the lifetime of wireles... more The efficient use of energy is an important performance target to prolong the lifetime of wireless sensor networks (WSNs). As the idle listening of sensor nodes result in primary energy waste, many typical MAC protocols are designed to save power by placing the radio in the low-power sleep mode. In this paper a new energy-efficient multi-layer MAC (ML-MAC) protocol is proposed for wireless sensor networks. It is designed with two main features: low duty cycle and low number of collisions. Sensor nodes in ML-MAC have a very short listening time which would reduce the energy required to communicate with other nodes. Also, the number of collisions in cases where two or more nodes try to send at the same time is minimized in ML-MAC. This saves the energy required to re-send the corrupted packets. Simulation results show much better performance of the energy consumption compared with the existing MAC protocols.

Research paper thumbnail of Effect of Sociocultural Cleavage on Genetic Differentiation: A Study from North India

Human Biology, Jan 1, 2008

Research paper thumbnail of Lattice vibrational properties of transition metal carbides (TiC, ZrC and HfC)

Pramana, Jan 1, 2005

Lattice vibrational properties of transition metal carbides (TiC, ZrC and HfC) have been presente... more Lattice vibrational properties of transition metal carbides (TiC, ZrC and HfC) have been presented by including the effects of free-carrier doping and three-body interactions in the rigid shell model. The short-range overlap repulsion is operative up to the second neighbour ions. An excellent agreement has been obtained between theory and experiment for their phonon dispersion curves and Debye temperature variations. It is concluded that the contributions of free-carrier doping and three-body interactions are essential for the description of the lattice dynamics of these carbides.

Research paper thumbnail of Adaptive logistic controller for integrated design of distributed supply chains

Journal of Manufacturing Systems, Jan 1, 2007

Usually each manufacturing stage in a supply chain makes its own decision regarding quantity and ... more Usually each manufacturing stage in a supply chain makes its own decision regarding quantity and timing of parts it purchases from its suppliers, thereby controlling its inventory position and overall supply chain dynamics. Such decisions, although good for each individual stage, can adversely affect the overall performance of the supply chain. This can be viewed as distributed control of inventory, in which each controller is making autonomous decisions based on local objectives. Because these controllers do not have information about inventory position or order quantities at other stages, the safety stock tends to be higher, leading to higher inventories and cost. This also causes demand amplification and the bullwhip effect. This paper presents a distributed feedback control algorithm, called the Adaptive Logistics Controller (ALC), which simultaneously decides the order quantities for each stage of the supply chain to minimize the total WIP in the entire supply chain for a given demand. In this approach, simulation is used to provide the feedback to the ALC controller, leading to an iterative numerical computational approach. Computational experiments compared with the traditional centralized (Q,r)(Q,r) policy model show that the order quantities calculated by the distributed ALC are much superior in terms of total overall WIP and hence result in lesser total costs for the entire supply chain.

Research paper thumbnail of A methodology for establishing cleanup objectives in the unsaturated soil zone using sensitivity and uncertainty analysis for chemical fate and transport

Soil & Sediment Contamination, Jan 1, 1999

* The submitted manuscript has been authored by a contractor of the US Government under contract ... more * The submitted manuscript has been authored by a contractor of the US Government under contract No. DE-AC05-96OR22464. Accordingly, the US Government retains a nonexclusive, royalty-free license to publish or reproduce the published form of this ...

Research paper thumbnail of Genetic affinities between endogamous and inbreeding populations of Uttar Pradesh

BMC Genetics, Jan 1, 2007

Background: India has experienced several waves of migration since the Middle Paleolithic. It is ... more Background: India has experienced several waves of migration since the Middle Paleolithic. It is believed that the initial demic movement into India was from Africa along the southern coastal route, approximately 60,000-85,000 years before present (ybp). It has also been reported that there were two other major colonization which included eastward diffusion of Neolithic farmers (Elamo Dravidians) from Middle East sometime between 10,000 and 7,000 ybp and a southern dispersal of Indo Europeans from Central Asia 3,000 ybp. Mongol entry during the thirteenth century A.D. as well as some possible minor incursions from South China 50,000 to 60,000 ybp may have also contributed to cultural, linguistic and genetic diversity in India. Therefore, the genetic affinity and relationship of Indians with other world populations and also within India are often contested. In the present study, we have attempted to offer a fresh and immaculate interpretation on the genetic relationships of different North Indian populations with other Indian and world populations.

Research paper thumbnail of Slow Electron Cooling in Colloidal Quantum Dots

Research paper thumbnail of Boosting quantum efficiency using multi-stage parametric amplification

Optics Communications, Jan 1, 2007

We develop a numerical simulation to demonstrate increased quantum efficiency that can be achieve... more We develop a numerical simulation to demonstrate increased quantum efficiency that can be achieved by using a second stage, phase matched crystal to convert signal energy to the idler wavelength. A pair of ZnGeP2 crystals with walkoff and pump absorption were simulated leading to a tripling of the idler output energy. The output beam characteristics are close to a Gaussian beam with an M2 around 1.1.

Research paper thumbnail of YAP, signature of an African-Middle Eastern migration into northern India

Curr Sci, Jan 1, 2005

YAP, an Alu insertion polymorphism found on human Y-chromosome is present in two lineages worldwi... more YAP, an Alu insertion polymorphism found on human Y-chromosome is present in two lineages worldwide, corresponding to M145/M203/SRY4064 (haplogroup E) and M145/M203/M174 (haplogroup D) polymorphisms respectively. First lineage belonging to haplogroup D is specific to Japan and other Southeast Asian populations, while haplogroup E is confined to Sub-Saharan African, Middle Eastern and Southern European populations. In the present study, 1021 Y-chromosomes belonging to nine different populations of North India were analysed for YAP insertion and four other single nucleotide polymorphisms (SNPs) to delineate the two lineages. Out of nine populations only one, i.e. Shiya Muslims revealed presence of YAP element at a frequency of 11%. Further analysis based on four additional SNPs revealed that all the YAP+ve samples could be categorized under African/Middle East-specific haplogroup E lineage. Interestingly, Sunni Muslims who historically have the same origin, i.e. from the Middle east showed a complete lack of YAP+ve lineage similar to other castes. We hypothesize that unlike Sunnis, Shiya Muslims due to their lesser number and less admixture with other caste groups of India, still carry the ancestral YAP+ve lineage, which in all probabilities is one of the founder haplogroups. All Middle Eastern populations show the presence of this lineage in almost similar frequency. Our study shows the presence of YAP+ve lineage in North Indian populations, reflecting an African/Middle Eastern migration into North India.

Research paper thumbnail of REM sleep deprivation of rats induces acute phase response in liver

Biochemical and biophysical research …, Jan 1, 2011

REM sleep is essential for maintenance of body physiology and its deprivation is fatal. We observ... more REM sleep is essential for maintenance of body physiology and its deprivation is fatal. We observed that the levels of ALT and AST enzymes and pro-inflammatory cytokines like IL-1β, IL-6 and IL-12 circulating in the blood of REM sleep deprived rats increased in proportion to the extent of sleep loss. But in contrast the levels of IFN-γ and a ∼200 kDa protein, identified by N-terminal sequencing to be alpha-1-inhibitor-3(A1I3), decreased significantly. Quantitative PCR analysis confirmed that REM sleep deprivation down regulates AII3 gene and up regulates IL1 β, IL6 and their respective receptors gene expression in the liver initiating its inflammation.► Concentration of A1I3, an acute phase response protein circulating in the serum decreased proportionately to the REM sleep loss. ► The level of ALT and AST in the serum increased proportionate to the extent of REM sleep loss. ► Pro-Inflammatory cytokines like IL-1β, IL-6, and IL-12 & IFN γ in the blood were found to be modulated. ► REM sleep deprivation up regulated IL-1 β, IL-1 β r, and IL-6, IL-6r genes expression in the liver.

Research paper thumbnail of An energy-efficient multi-layer MAC (ML-MAC) protocol for wireless sensor networks

AEU-International Journal of …, Jan 1, 2011

The efficient use of energy is an important performance target to prolong the lifetime of wireles... more The efficient use of energy is an important performance target to prolong the lifetime of wireless sensor networks (WSNs). As the idle listening of sensor nodes result in primary energy waste, many typical MAC protocols are designed to save power by placing the radio in the low-power sleep mode. In this paper a new energy-efficient multi-layer MAC (ML-MAC) protocol is proposed for wireless sensor networks. It is designed with two main features: low duty cycle and low number of collisions. Sensor nodes in ML-MAC have a very short listening time which would reduce the energy required to communicate with other nodes. Also, the number of collisions in cases where two or more nodes try to send at the same time is minimized in ML-MAC. This saves the energy required to re-send the corrupted packets. Simulation results show much better performance of the energy consumption compared with the existing MAC protocols.

Research paper thumbnail of Effect of Sociocultural Cleavage on Genetic Differentiation: A Study from North India

Human Biology, Jan 1, 2008

Research paper thumbnail of Lattice vibrational properties of transition metal carbides (TiC, ZrC and HfC)

Pramana, Jan 1, 2005

Lattice vibrational properties of transition metal carbides (TiC, ZrC and HfC) have been presente... more Lattice vibrational properties of transition metal carbides (TiC, ZrC and HfC) have been presented by including the effects of free-carrier doping and three-body interactions in the rigid shell model. The short-range overlap repulsion is operative up to the second neighbour ions. An excellent agreement has been obtained between theory and experiment for their phonon dispersion curves and Debye temperature variations. It is concluded that the contributions of free-carrier doping and three-body interactions are essential for the description of the lattice dynamics of these carbides.

Research paper thumbnail of Adaptive logistic controller for integrated design of distributed supply chains

Journal of Manufacturing Systems, Jan 1, 2007

Usually each manufacturing stage in a supply chain makes its own decision regarding quantity and ... more Usually each manufacturing stage in a supply chain makes its own decision regarding quantity and timing of parts it purchases from its suppliers, thereby controlling its inventory position and overall supply chain dynamics. Such decisions, although good for each individual stage, can adversely affect the overall performance of the supply chain. This can be viewed as distributed control of inventory, in which each controller is making autonomous decisions based on local objectives. Because these controllers do not have information about inventory position or order quantities at other stages, the safety stock tends to be higher, leading to higher inventories and cost. This also causes demand amplification and the bullwhip effect. This paper presents a distributed feedback control algorithm, called the Adaptive Logistics Controller (ALC), which simultaneously decides the order quantities for each stage of the supply chain to minimize the total WIP in the entire supply chain for a given demand. In this approach, simulation is used to provide the feedback to the ALC controller, leading to an iterative numerical computational approach. Computational experiments compared with the traditional centralized (Q,r)(Q,r) policy model show that the order quantities calculated by the distributed ALC are much superior in terms of total overall WIP and hence result in lesser total costs for the entire supply chain.

Research paper thumbnail of A methodology for establishing cleanup objectives in the unsaturated soil zone using sensitivity and uncertainty analysis for chemical fate and transport

Soil & Sediment Contamination, Jan 1, 1999

* The submitted manuscript has been authored by a contractor of the US Government under contract ... more * The submitted manuscript has been authored by a contractor of the US Government under contract No. DE-AC05-96OR22464. Accordingly, the US Government retains a nonexclusive, royalty-free license to publish or reproduce the published form of this ...

Research paper thumbnail of Genetic affinities between endogamous and inbreeding populations of Uttar Pradesh

BMC Genetics, Jan 1, 2007

Background: India has experienced several waves of migration since the Middle Paleolithic. It is ... more Background: India has experienced several waves of migration since the Middle Paleolithic. It is believed that the initial demic movement into India was from Africa along the southern coastal route, approximately 60,000-85,000 years before present (ybp). It has also been reported that there were two other major colonization which included eastward diffusion of Neolithic farmers (Elamo Dravidians) from Middle East sometime between 10,000 and 7,000 ybp and a southern dispersal of Indo Europeans from Central Asia 3,000 ybp. Mongol entry during the thirteenth century A.D. as well as some possible minor incursions from South China 50,000 to 60,000 ybp may have also contributed to cultural, linguistic and genetic diversity in India. Therefore, the genetic affinity and relationship of Indians with other world populations and also within India are often contested. In the present study, we have attempted to offer a fresh and immaculate interpretation on the genetic relationships of different North Indian populations with other Indian and world populations.

Research paper thumbnail of Slow Electron Cooling in Colloidal Quantum Dots

Research paper thumbnail of Boosting quantum efficiency using multi-stage parametric amplification

Optics Communications, Jan 1, 2007

We develop a numerical simulation to demonstrate increased quantum efficiency that can be achieve... more We develop a numerical simulation to demonstrate increased quantum efficiency that can be achieved by using a second stage, phase matched crystal to convert signal energy to the idler wavelength. A pair of ZnGeP2 crystals with walkoff and pump absorption were simulated leading to a tripling of the idler output energy. The output beam characteristics are close to a Gaussian beam with an M2 around 1.1.

Research paper thumbnail of YAP, signature of an African-Middle Eastern migration into northern India

Curr Sci, Jan 1, 2005

YAP, an Alu insertion polymorphism found on human Y-chromosome is present in two lineages worldwi... more YAP, an Alu insertion polymorphism found on human Y-chromosome is present in two lineages worldwide, corresponding to M145/M203/SRY4064 (haplogroup E) and M145/M203/M174 (haplogroup D) polymorphisms respectively. First lineage belonging to haplogroup D is specific to Japan and other Southeast Asian populations, while haplogroup E is confined to Sub-Saharan African, Middle Eastern and Southern European populations. In the present study, 1021 Y-chromosomes belonging to nine different populations of North India were analysed for YAP insertion and four other single nucleotide polymorphisms (SNPs) to delineate the two lineages. Out of nine populations only one, i.e. Shiya Muslims revealed presence of YAP element at a frequency of 11%. Further analysis based on four additional SNPs revealed that all the YAP+ve samples could be categorized under African/Middle East-specific haplogroup E lineage. Interestingly, Sunni Muslims who historically have the same origin, i.e. from the Middle east showed a complete lack of YAP+ve lineage similar to other castes. We hypothesize that unlike Sunnis, Shiya Muslims due to their lesser number and less admixture with other caste groups of India, still carry the ancestral YAP+ve lineage, which in all probabilities is one of the founder haplogroups. All Middle Eastern populations show the presence of this lineage in almost similar frequency. Our study shows the presence of YAP+ve lineage in North Indian populations, reflecting an African/Middle Eastern migration into North India.