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National Centre For Biological Sciences, Bangalore, India
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Papers by poo patel
Journal of Cell Biology, 1985
The application of DC electric fields to cells has a long and contentious history. The interpreta... more The application of DC electric fields to cells has a long and contentious history. The interpretation of the response of cells to such fields was hampered by lack of adequate recording technique, contamination of cultures by electrode products, uncertainty about the magnitude of fields, and sometimes by the complexity of the biological system under study. Nevertheless, when Jaffe and Nuccitelli (12) reviewed the literature in 1977, they found eight reliable reports of the response of plant cells to applied fields and four of animal cells. Since then, several laboratories have applied electrical fields to isolated cells in culture and recorded the responses on film or video tape so that responses could be characterized carefully and the threshold field strengths established. In these later studies, the size and direction of the fields are known unambiguously and possible artifacts such as electrode products, nutrient gradients, flow effects, and temperature changes are controlled.
Journal of Cell Biology, 1985
The application of DC electric fields to cells has a long and contentious history. The interpreta... more The application of DC electric fields to cells has a long and contentious history. The interpretation of the response of cells to such fields was hampered by lack of adequate recording technique, contamination of cultures by electrode products, uncertainty about the magnitude of fields, and sometimes by the complexity of the biological system under study. Nevertheless, when Jaffe and Nuccitelli (12) reviewed the literature in 1977, they found eight reliable reports of the response of plant cells to applied fields and four of animal cells. Since then, several laboratories have applied electrical fields to isolated cells in culture and recorded the responses on film or video tape so that responses could be characterized carefully and the threshold field strengths established. In these later studies, the size and direction of the fields are known unambiguously and possible artifacts such as electrode products, nutrient gradients, flow effects, and temperature changes are controlled.